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EA200970779A1 - Новое сульфированное соединение сахара и его применение в качестве лекарственного средства - Google Patents

Новое сульфированное соединение сахара и его применение в качестве лекарственного средства

Info

Publication number
EA200970779A1
EA200970779A1 EA200970779A EA200970779A EA200970779A1 EA 200970779 A1 EA200970779 A1 EA 200970779A1 EA 200970779 A EA200970779 A EA 200970779A EA 200970779 A EA200970779 A EA 200970779A EA 200970779 A1 EA200970779 A1 EA 200970779A1
Authority
EA
Eurasian Patent Office
Prior art keywords
sugar
medicine
connection
application
sulphated
Prior art date
Application number
EA200970779A
Other languages
English (en)
Other versions
EA016931B1 (ru
Inventor
Кейсуке Охта
Масахико Миура
Кенго Сакагути
Фумио Сугавара
Нориюки Сато
Хироеки Сахара
Нобуаки Такахаси
Йоко Мори
Такаюки Ямазаки
Казуйоси Масаки
Хироси Мурата
Original Assignee
Тойо Суйсан Кайся, Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Тойо Суйсан Кайся, Лтд. filed Critical Тойо Суйсан Кайся, Лтд.
Publication of EA200970779A1 publication Critical patent/EA200970779A1/ru
Publication of EA016931B1 publication Critical patent/EA016931B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Предложено сульфохиновозилацилпропанидольное соединение, представленное общей формулой (I):(где Rпредставляет собой ацильный остаток жирной кислоты и М представляет собой атом водорода или ион металла) или его фармацевтически приемлемые соли.
EA200970779A 2007-07-20 2008-07-18 Новое сульфированное соединение сахара и его применение в качестве лекарственного средства EA016931B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007190120 2007-07-20
PCT/JP2008/063056 WO2009014101A1 (ja) 2007-07-20 2008-07-18 新規なスルホン酸化糖誘導体およびその医薬としての使用

Publications (2)

Publication Number Publication Date
EA200970779A1 true EA200970779A1 (ru) 2010-04-30
EA016931B1 EA016931B1 (ru) 2012-08-30

Family

ID=40281352

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200970779A EA016931B1 (ru) 2007-07-20 2008-07-18 Новое сульфированное соединение сахара и его применение в качестве лекарственного средства

Country Status (10)

Country Link
US (2) US7973145B2 (ru)
EP (1) EP2130834A4 (ru)
JP (1) JP4435861B2 (ru)
KR (1) KR101136601B1 (ru)
CN (1) CN101641365B (ru)
AU (1) AU2008278337B2 (ru)
BR (1) BRPI0809936A2 (ru)
CA (1) CA2679915C (ru)
EA (1) EA016931B1 (ru)
WO (1) WO2009014101A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9950194B2 (en) 2014-09-09 2018-04-24 Mevion Medical Systems, Inc. Patient positioning system
CN106380400B (zh) * 2016-02-04 2018-12-11 浙江省中医药研究院 一种萜品烯醇类化合物及其制备方法和应用
JP6621158B1 (ja) * 2019-03-05 2019-12-18 株式会社エム・ティー・スリー 放射線増感剤
JP6903273B1 (ja) 2020-09-25 2021-07-14 株式会社エム・ティー・スリー 化合物又はその塩、及び放射性増感剤
CN117860899A (zh) * 2022-10-11 2024-04-12 M.T.3株式会社 化合物或其药学上可接受的盐制备用于治疗癌症的药物组合物的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0486536T3 (da) * 1989-08-15 1995-04-10 Us Health Antivirale midler midler indeholdende sulfoquinovosylglycerolderivater og analoger deraf
JP4454051B2 (ja) * 1997-01-24 2010-04-21 東洋水産株式会社 新規な糖脂質、その製造方法及びその用途
JP3851461B2 (ja) 1998-09-04 2006-11-29 東洋水産株式会社 ピラノシドおよびその製造方法
JP4224429B2 (ja) * 1998-09-04 2009-02-12 東洋水産株式会社 スルホキノボシルアシルグリセロール
US6518410B2 (en) * 1999-02-26 2003-02-11 Toyo Suisan Kaisha, Ltd. Sulfoquinovosylacylglycerol derivative, and use thereof as medicaments
JP3771445B2 (ja) * 1999-02-26 2006-04-26 東洋水産株式会社 スルホピラノシルアシルグリセロール誘導体を含有する制癌剤
AU765950B2 (en) * 1999-03-11 2003-10-02 Toyo Suisan Kaisha, Ltd. Novel immunosuppressants
JP4913289B2 (ja) * 2001-05-23 2012-04-11 備前化成株式会社 カスパーゼ阻害剤
JP4281377B2 (ja) 2003-02-26 2009-06-17 東レ株式会社 液晶性ポリエステルおよびその組成物
CA2567306C (en) * 2004-06-24 2011-06-07 Toyo Suisan Kaisha, Ltd. Radiosensitizer

Also Published As

Publication number Publication date
CN101641365B (zh) 2013-01-16
CA2679915A1 (en) 2009-01-29
BRPI0809936A2 (pt) 2014-10-07
EP2130834A4 (en) 2012-09-05
KR20090122451A (ko) 2009-11-30
US20100298246A1 (en) 2010-11-25
AU2008278337A1 (en) 2009-01-29
CA2679915C (en) 2012-10-30
JPWO2009014101A1 (ja) 2010-10-07
AU2008278337B2 (en) 2011-09-29
US20090209475A1 (en) 2009-08-20
JP4435861B2 (ja) 2010-03-24
KR101136601B1 (ko) 2012-04-23
WO2009014101A1 (ja) 2009-01-29
EA016931B1 (ru) 2012-08-30
CN101641365A (zh) 2010-02-03
EP2130834A1 (en) 2009-12-09
US7973145B2 (en) 2011-07-05

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU