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EA200200189A1 - Применение ингибиторов интерлейкина 18 - Google Patents

Применение ингибиторов интерлейкина 18

Info

Publication number
EA200200189A1
EA200200189A1 EA200200189A EA200200189A EA200200189A1 EA 200200189 A1 EA200200189 A1 EA 200200189A1 EA 200200189 A EA200200189 A EA 200200189A EA 200200189 A EA200200189 A EA 200200189A EA 200200189 A1 EA200200189 A1 EA 200200189A1
Authority
EA
Eurasian Patent Office
Prior art keywords
application
interleukin inhibitors
inhibitors
interleukin
published
Prior art date
Application number
EA200200189A
Other languages
English (en)
Other versions
EA005419B1 (ru
Inventor
Чарльз Динарелло
Original Assignee
Йеда Рисерч Энд Дивелопмент Ко. Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Йеда Рисерч Энд Дивелопмент Ко. Лтд. filed Critical Йеда Рисерч Энд Дивелопмент Ко. Лтд.
Publication of EA200200189A1 publication Critical patent/EA200200189A1/ru
Publication of EA005419B1 publication Critical patent/EA005419B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Раскрыто применение ингибиторов ИЛ-18 при метастазах опухолей.Отчет о международном поиске был опубликован 2001.05.10.
EA200200189A 1999-07-22 2000-07-17 Применение ингибиторов интерлейкина-18 для приготовления лекарственного средства для подавления метастазов опухолей EA005419B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13104799A IL131047A0 (en) 1999-07-22 1999-07-22 Use of il-18 inhibitors
PCT/IL2000/000419 WO2001007480A2 (en) 1999-07-22 2000-07-17 Use of interleukin-18 inhibitors to inhibit tumor metastasis

Publications (2)

Publication Number Publication Date
EA200200189A1 true EA200200189A1 (ru) 2002-12-26
EA005419B1 EA005419B1 (ru) 2005-02-24

Family

ID=11073044

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200189A EA005419B1 (ru) 1999-07-22 2000-07-17 Применение ингибиторов интерлейкина-18 для приготовления лекарственного средства для подавления метастазов опухолей

Country Status (31)

Country Link
US (1) US7741276B2 (ru)
EP (1) EP1206274B1 (ru)
JP (1) JP4827352B2 (ru)
KR (1) KR100682219B1 (ru)
CN (1) CN1173736C (ru)
AR (1) AR024907A1 (ru)
AT (1) ATE363288T1 (ru)
AU (1) AU782478B2 (ru)
BG (1) BG65800B1 (ru)
BR (1) BR0012675A (ru)
CA (1) CA2380216C (ru)
CY (1) CY1107932T1 (ru)
CZ (1) CZ302114B6 (ru)
DE (2) DE1206274T1 (ru)
DK (1) DK1206274T3 (ru)
EA (1) EA005419B1 (ru)
EE (1) EE04838B1 (ru)
ES (1) ES2186596T3 (ru)
HK (1) HK1048248B (ru)
HU (1) HU228780B1 (ru)
IL (2) IL131047A0 (ru)
MX (1) MXPA02000838A (ru)
NO (1) NO329827B1 (ru)
NZ (1) NZ516535A (ru)
PL (1) PL202477B1 (ru)
PT (1) PT1206274E (ru)
SK (1) SK287522B6 (ru)
TR (1) TR200200169T2 (ru)
UA (1) UA73745C2 (ru)
WO (1) WO2001007480A2 (ru)
ZA (1) ZA200200390B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001236807A1 (en) 2000-02-10 2001-08-20 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
US6894155B2 (en) 2000-10-11 2005-05-17 Viron Therapeutics Nucleic acid molecules and polypeptides for immune modulation
US7718368B2 (en) 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
MXPA05003869A (es) * 2002-10-08 2005-06-22 Ares Trading Sa El uso de citocina capaz de enlazarse a la proteina de union a interleucina-18, y de inhibir la actividad de una segunda citocina.
US7968684B2 (en) * 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
SI2267024T1 (sl) 2005-06-03 2012-09-28 Ares Trading Sa Proizvodnja rekombinantnega IL-18 vezavnega proteina
ES2375831T3 (es) 2005-06-10 2012-03-06 Ares Trading S.A. Procedimiento para la purificación de prote�?nas de unión a il-18.
CL2008002153A1 (es) 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
US9812033B2 (en) * 2013-03-06 2017-11-07 Venkatesh R. Chari Tactile graphic display
WO2023178192A1 (en) 2022-03-15 2023-09-21 Compugen Ltd. Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0662003B1 (en) * 1992-09-02 2003-01-29 Isis Pharmaceuticals, Inc. Oligonucleotide modulation of cell adhesion
US7141393B2 (en) * 1996-12-26 2006-11-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18-receptor proteins
IL131815A0 (en) * 1997-03-18 2001-03-19 Basf Ag Methods and compositions for modulating responsiveness to corticosteroids
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use

Also Published As

Publication number Publication date
AR024907A1 (es) 2002-10-30
NZ516535A (en) 2004-04-30
EP1206274A2 (en) 2002-05-22
CA2380216A1 (en) 2001-02-01
TR200200169T2 (tr) 2002-06-21
WO2001007480A3 (en) 2001-05-10
CZ2002195A3 (cs) 2002-06-12
EE200200032A (et) 2003-02-17
EE04838B1 (et) 2007-06-15
KR20020027493A (ko) 2002-04-13
DK1206274T3 (da) 2007-08-13
KR100682219B1 (ko) 2007-02-12
IL147675A (en) 2009-05-04
HU228780B1 (en) 2013-05-28
US7741276B2 (en) 2010-06-22
NO20020153D0 (no) 2002-01-11
IL131047A0 (en) 2001-01-28
HK1048248A1 (en) 2003-03-28
BR0012675A (pt) 2002-04-09
ZA200200390B (en) 2003-04-30
CZ302114B6 (cs) 2010-10-20
DE60035049D1 (de) 2007-07-12
NO329827B1 (no) 2011-01-03
ES2186596T1 (es) 2003-05-16
ATE363288T1 (de) 2007-06-15
CN1173736C (zh) 2004-11-03
HUP0202107A3 (en) 2005-01-28
DE1206274T1 (de) 2002-11-14
PL202477B1 (pl) 2009-06-30
SK882002A3 (en) 2002-07-02
AU782478B2 (en) 2005-08-04
HUP0202107A2 (en) 2002-10-28
WO2001007480A2 (en) 2001-02-01
MXPA02000838A (es) 2002-07-30
BRPI0012675B8 (ru) 2021-05-25
CN1364086A (zh) 2002-08-14
CA2380216C (en) 2012-01-31
AU5843200A (en) 2001-02-13
BG106311A (en) 2002-08-30
NO20020153L (no) 2002-03-11
EA005419B1 (ru) 2005-02-24
SK287522B6 (sk) 2011-01-04
US20080003216A1 (en) 2008-01-03
EP1206274B1 (en) 2007-05-30
ES2186596T3 (es) 2007-11-16
CY1107932T1 (el) 2013-09-04
HK1048248B (zh) 2005-04-22
JP2003505472A (ja) 2003-02-12
PL353732A1 (en) 2003-12-01
PT1206274E (pt) 2007-07-06
BG65800B1 (bg) 2009-12-31
JP4827352B2 (ja) 2011-11-30
BRPI0012675B1 (pt) 2001-02-01
DE60035049T2 (de) 2007-09-27
UA73745C2 (en) 2005-09-15

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MK4A Patent expired

Designated state(s): RU