EA199901049A2 - Спироимидазолиновые соединения, способ их получения и фармацевтическая композиция, содержащая их - Google Patents
Спироимидазолиновые соединения, способ их получения и фармацевтическая композиция, содержащая ихInfo
- Publication number
- EA199901049A2 EA199901049A2 EA199901049A EA199901049A EA199901049A2 EA 199901049 A2 EA199901049 A2 EA 199901049A2 EA 199901049 A EA199901049 A EA 199901049A EA 199901049 A EA199901049 A EA 199901049A EA 199901049 A2 EA199901049 A2 EA 199901049A2
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- preparation
- spiro
- pharmaceutical composition
- composition containing
- imidazoline compounds
- Prior art date
Links
- -1 Spiro imidazoline compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002636 imidazolinyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Изобретение относится к новым спироимидазолиновым соединениям формулы (I)в которой A представляет необязательно замещенное бензольное кольцо, B представляет имидазолиновое кольцо формулы (Ia) или (Ib)к способу их получения и лекарственным средствам.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9816000A FR2787450B1 (fr) | 1998-12-18 | 1998-12-18 | Nouveaux derives spiroimidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EA199901049A3 EA199901049A3 (ru) | 2000-08-28 |
| EA199901049A2 true EA199901049A2 (ru) | 2000-08-28 |
| EA002979B1 EA002979B1 (ru) | 2002-12-26 |
Family
ID=9534134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA199901049A EA002979B1 (ru) | 1998-12-18 | 1999-12-17 | Спироимидазолиновые соединения, способ их получения и фармацевтическая композиция, содержащая их |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6172097B1 (ru) |
| EP (1) | EP1010694B1 (ru) |
| JP (1) | JP3457241B2 (ru) |
| KR (1) | KR100472522B1 (ru) |
| CN (1) | CN1149201C (ru) |
| AT (1) | ATE246680T1 (ru) |
| AU (1) | AU760373B2 (ru) |
| BR (1) | BR9905904A (ru) |
| CA (1) | CA2292920C (ru) |
| DE (1) | DE69910156T2 (ru) |
| DK (1) | DK1010694T3 (ru) |
| EA (1) | EA002979B1 (ru) |
| ES (1) | ES2205741T3 (ru) |
| FR (1) | FR2787450B1 (ru) |
| HK (1) | HK1029117A1 (ru) |
| HU (1) | HU225820B1 (ru) |
| NO (1) | NO314402B1 (ru) |
| NZ (1) | NZ501890A (ru) |
| PL (1) | PL202368B1 (ru) |
| PT (1) | PT1010694E (ru) |
| SI (1) | SI1010694T1 (ru) |
| ZA (1) | ZA997735B (ru) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6638981B2 (en) | 2001-08-17 | 2003-10-28 | Epicept Corporation | Topical compositions and methods for treating pain |
| EP2254420A4 (en) | 2008-02-20 | 2012-02-15 | Targia Pharmaceuticals | CNS PHARMACEUTICALS AND METHOD FOR THEIR USE |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6294185B1 (en) * | 1993-03-12 | 2001-09-25 | Auburn University | Monomeric and polymeric cyclic amine and N-halamine compounds |
| FR2707981B1 (fr) * | 1993-07-20 | 1995-09-01 | Adir | Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2707982B1 (fr) * | 1993-07-20 | 1995-09-01 | Adir | Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2709306B1 (fr) * | 1993-07-20 | 1995-10-20 | Adir | Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
-
1998
- 1998-12-18 FR FR9816000A patent/FR2787450B1/fr not_active Expired - Fee Related
-
1999
- 1999-12-16 JP JP35716799A patent/JP3457241B2/ja not_active Expired - Fee Related
- 1999-12-17 US US09/465,619 patent/US6172097B1/en not_active Expired - Fee Related
- 1999-12-17 PT PT99403189T patent/PT1010694E/pt unknown
- 1999-12-17 DE DE69910156T patent/DE69910156T2/de not_active Expired - Lifetime
- 1999-12-17 BR BR9905904-5A patent/BR9905904A/pt not_active Application Discontinuation
- 1999-12-17 ZA ZA9907735A patent/ZA997735B/xx unknown
- 1999-12-17 PL PL337265A patent/PL202368B1/pl not_active IP Right Cessation
- 1999-12-17 EA EA199901049A patent/EA002979B1/ru not_active IP Right Cessation
- 1999-12-17 SI SI9930368T patent/SI1010694T1/xx unknown
- 1999-12-17 NO NO19996285A patent/NO314402B1/no not_active IP Right Cessation
- 1999-12-17 CA CA002292920A patent/CA2292920C/fr not_active Expired - Fee Related
- 1999-12-17 ES ES99403189T patent/ES2205741T3/es not_active Expired - Lifetime
- 1999-12-17 HU HU9904629A patent/HU225820B1/hu not_active IP Right Cessation
- 1999-12-17 AU AU65291/99A patent/AU760373B2/en not_active Ceased
- 1999-12-17 CN CNB991278305A patent/CN1149201C/zh not_active Expired - Fee Related
- 1999-12-17 EP EP99403189A patent/EP1010694B1/fr not_active Expired - Lifetime
- 1999-12-17 AT AT99403189T patent/ATE246680T1/de not_active IP Right Cessation
- 1999-12-17 DK DK99403189T patent/DK1010694T3/da active
- 1999-12-17 NZ NZ501890A patent/NZ501890A/xx not_active IP Right Cessation
- 1999-12-18 KR KR10-1999-0058931A patent/KR100472522B1/ko not_active IP Right Cessation
-
2000
- 2000-12-28 HK HK00108451A patent/HK1029117A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA199800290A1 (ru) | (метилсульфонил) фенил-2-(5н)-фураноны в качестве ингибиторов циклооксигеназы-2 | |
| YU56995A (sh) | Soli derivata indola | |
| ES2154167A1 (es) | Aminoderivados ciclicos antagonistas del receptor ccr-3. | |
| UY26511A1 (es) | Bases de mannich indólicas, procedimientos para su preparación, medicamentos que contienen estos compuestos y su uso para la preparación de medicamentos | |
| CY1105387T1 (el) | Υποκατεστημενα παραγωγα 2-διαλκυλαμινοαλκυλοδιφαινθλιου | |
| AR019365A1 (es) | Compuesto de 1-piperidin-3-fenil-butil-naftamida, proceso para prepararlo, composicion farmaceutica y uso para fabricar un medicamento util para eltratamiento de una enfermedad por antagonistas de taquicininas neuropeptidicas endogenas | |
| TR200101412T2 (tr) | Yeni bileşikler. | |
| ECSP034531A (es) | Derivados sustituidos de c-ciclohexilmetilamina | |
| EA200000431A3 (ru) | Новые замещенные димерные соединения, способ их получения и фармацевтические композиции, содержащие их | |
| EA200100090A2 (ru) | Новые пиперидин-4-сульфонамидные производные, способ их получения и содержащие их фармацевтические композиции | |
| EA200300044A1 (ru) | Новые замещенные фталиды, способ их получения и содержащие их фармацевтические композиции | |
| DZ1468A1 (fr) | Composés nouveaux. | |
| NO963331L (no) | 5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister | |
| BR0114380A (pt) | Derivados-1-aminobutan-3-ol-substituìdos | |
| NO980688D0 (no) | Sammenföyde isoquinoliner som dopamin-reseptor-ligander | |
| EA199901049A2 (ru) | Спироимидазолиновые соединения, способ их получения и фармацевтическая композиция, содержащая их | |
| BR9610175A (pt) | Composto processo de preparação do composto composição farmacêutica e utilização do composto | |
| EA199700223A1 (ru) | Бициклические антагонисты тахикининов, их получение и применение в фармацевтической композиции | |
| EA200000530A1 (ru) | НОВЫЕ 19-НОРСТЕРОИДЫ, ЗАМЕЩЕННЫЕ В ПОЛОЖЕНИИ 11β, СПОСОБ И ПРОМЕЖУТОЧНЫЕ ПРОДУКТЫ ДЛЯ ИХ ПОЛУЧЕНИЯ, ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННЫХ СРЕДСТВ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ | |
| IT1210926B (it) | Derivati della 1-metil-5-nitro-imidazolina e composizioni terapeutiche che li comprendono come principio attivo. | |
| AR027058A1 (es) | Bases pirrolicas sustituidas de mannich, procedimiento para su preparacion, medicamentos que contienen compuestos y uso de estos compuestos para lapreparacion de medicamentos | |
| BR0014145A (pt) | Compostos de benzimidazol substituìdo por alcóxi, preparações farmacêuticas contendo o mesmo, e métodos de uso do mesmo | |
| BR9913601A (pt) | Composto, uso do mesmo, composição farmacêutica, e, processo para a preparação de compostos | |
| EA200000261A3 (ru) | Новые замещенные димерные соединения, способ их получения и содержащияся их фармацевтическая композиция | |
| UY26509A1 (es) | Bases pirrolicas sustituidas de mannich, procedimiento para su preparación, medicamentos que contienen estos compuestos, y uso del compuesto para la preparación de medicamentos. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |