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DZ2448A1 - Sel du dérivé d'acide de naphthyridine carboxylique. - Google Patents

Sel du dérivé d'acide de naphthyridine carboxylique.

Info

Publication number
DZ2448A1
DZ2448A1 DZ980058A DZ980058A DZ2448A1 DZ 2448 A1 DZ2448 A1 DZ 2448A1 DZ 980058 A DZ980058 A DZ 980058A DZ 980058 A DZ980058 A DZ 980058A DZ 2448 A1 DZ2448 A1 DZ 2448A1
Authority
DZ
Algeria
Prior art keywords
salt
carboxylic acid
acid derivative
naphthyridine carboxylic
naphthyridine
Prior art date
Application number
DZ980058A
Other languages
English (en)
French (fr)
Inventor
Ae Ri Kim
Jin Hwa Lee
Ki Sook Park
Jong Ryoo Choi
Tae Hee Lee
Jay Hyok Chang
Do Hyun Nam
Hoon Choi
Original Assignee
Lg Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Chemicals Ltd filed Critical Lg Chemicals Ltd
Application granted granted Critical
Publication of DZ2448A1 publication Critical patent/DZ2448A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DZ980058A 1997-03-21 1998-03-18 Sel du dérivé d'acide de naphthyridine carboxylique. DZ2448A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR19970009840 1997-03-21

Publications (1)

Publication Number Publication Date
DZ2448A1 true DZ2448A1 (fr) 2003-01-11

Family

ID=19500439

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ980058A DZ2448A1 (fr) 1997-03-21 1998-03-18 Sel du dérivé d'acide de naphthyridine carboxylique.

Country Status (39)

Country Link
US (9) US7700617B2 (hu)
EP (2) EP1179533B1 (hu)
JP (3) JP3759962B2 (hu)
KR (1) KR100266499B1 (hu)
CN (1) CN1131229C (hu)
AP (1) AP1331A (hu)
AR (1) AR012125A1 (hu)
AT (2) ATE239724T1 (hu)
AU (1) AU726634B2 (hu)
BG (1) BG63972B1 (hu)
BR (1) BR9808290A (hu)
CA (1) CA2283671C (hu)
CZ (2) CZ288673B6 (hu)
DE (2) DE69821147T2 (hu)
DK (2) DK1179533T3 (hu)
DZ (1) DZ2448A1 (hu)
EA (1) EA001674B1 (hu)
ES (2) ES2213669T3 (hu)
HK (1) HK1026698A1 (hu)
HU (2) HU227536B1 (hu)
ID (1) ID22681A (hu)
IL (2) IL131812A0 (hu)
IN (1) IN188178B (hu)
IS (2) IS2093B (hu)
MA (1) MA24500A1 (hu)
MY (1) MY137653A (hu)
NO (1) NO312515B1 (hu)
NZ (1) NZ337748A (hu)
OA (1) OA11161A (hu)
PE (1) PE67999A1 (hu)
PL (1) PL191815B1 (hu)
PT (2) PT981527E (hu)
SA (1) SA98181055B1 (hu)
SI (2) SI0981527T1 (hu)
SK (1) SK284107B6 (hu)
TR (1) TR199902313T2 (hu)
UA (1) UA56218C2 (hu)
WO (1) WO1998042705A1 (hu)
ZA (1) ZA982335B (hu)

Families Citing this family (26)

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GB9820405D0 (en) * 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
KR20020038567A (ko) * 1999-03-19 2002-05-23 독터. 호르스트 하스칼, 잉에 린스 골관절염의 치료방법
US6262071B1 (en) 1999-06-29 2001-07-17 Smithkline Beecham Corporation Methods of use of antimicrobial compounds against pathogenic amycoplasma bacteria
US6331550B1 (en) 1999-06-29 2001-12-18 Smithkline Beecham Corporation Methods of use of quinolone compounds against anaerobic pathogenic bacteria
US6803376B1 (en) 1999-06-29 2004-10-12 Smithkline Beecham Corporation Method of use of quinolone compounds against pneumococcal and haemophilus bacteria
CA2282066C (en) 1999-06-29 2010-09-07 Smithkline Beecham Corporation Methods of use of quinolone compounds against atypical upper respiratory pathogenic bacteria
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
GB9920919D0 (en) * 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
JP2001097864A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 呼吸管および尿路病原性細菌に対するフルオロキノリン化合物の使用方法
WO2001021176A1 (en) * 1999-09-22 2001-03-29 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against bacteria
JP2001097891A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 呼吸器系病原菌に対するフルオロキノロン化合物の使用法
JP2001097863A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 嫌気性病原菌に対するフルオロキノロン化合物の使用法
GR1003520B (el) * 1999-09-22 2001-01-22 Smithkline Beecham Plc Μεθοδος χρησης ενωσεων φλουοροκινολονης εναντια σε νοσοκομειακα αρνητικα κατα gramμ παθογενων βακτηριδιων
GR1003521B (el) * 1999-09-23 2001-01-22 Smithkline Beecham Plc Μεθοδοι χρησεως ενωσεων φλουοροκινολονης εναντια κατα gram θετικων παθογονων βακτηριδιων
KR20010091379A (ko) * 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
ATE410225T1 (de) 2001-08-02 2008-10-15 Lg Life Sciences Ltd Verfahren zur herstellung von amino-geschützten 4-aminomethylene-pyrrolidin-3-on-derivaten, gemifloxacin und deren salze
DK1458391T3 (da) * 2001-11-30 2008-01-07 Lg Life Sciences Ltd Fremgangsmåde til at behandle bakterielle infektioner ved anvendelse af gemifloxacin eller et salt deraf og et beta-lactamantibiotikum
KR100517638B1 (ko) 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
AR043880A1 (es) * 2003-04-22 2005-08-17 Solvay Pharm Gmbh Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas
EP1891037A1 (en) * 2005-06-15 2008-02-27 Hetero Drugs Limited Gemifloxacin process and polymorphs
JP5384119B2 (ja) * 2006-03-07 2014-01-08 ウォックハート リミテッド ベンゾキノリジン−2−カルボン酸のプロドラッグ
WO2010001408A2 (en) * 2008-06-06 2010-01-07 Matrix Laboratories Ltd. Novel polymorphic forms of gemifloxacin mesylate
WO2010146594A1 (en) * 2009-06-16 2010-12-23 Hetero Research Foundation Novel polymorphs of gemifloxacin mesylate
EP2491921A1 (en) 2011-02-25 2012-08-29 Deva Holding Anonim Sirketi Conservation of anhydrous form of gemifloxacin
SG11201404834XA (en) * 2012-02-27 2014-09-26 Bristol Myers Squibb Co N- (5s, 6s, 9r) - 5 -amino- 6 - (2, 3 - difluorophenyl) -6, 7, 8, 9 - tetrahydro - 5h - cyclohepta [b] pyridin-9 -yl- 4 - (2 - oxo-2, 3 - dihydro - 1h- imidazo [4, 5 -b] pyridin - 1 - yl) piperidine - 1 - carboxylate, hemisulfate salt
CZ2016104A3 (cs) * 2016-02-24 2017-09-06 Zentiva, K.S. Krystalické modifikace solí methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}fenyl)amino](fenyl)methyliden}-2-oxo-2,3-dihydro-1H-indol-6-karboxylátu a způsoby jejich přípravy

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AR223983A1 (es) 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
HU188181B (en) 1981-06-11 1986-03-28 Warner-Lambert Co,Us Process for producing salts of naphtiridine and quinoline compounds of antimicrobial activity
IN162769B (hu) 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
NZ222047A (en) 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (ja) 1987-10-13 1989-04-18 Shionogi & Co Ltd オキシムまたはヒドロキシアミン誘導体系抗菌剤
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
US4931446A (en) 1988-03-23 1990-06-05 Abbott Laboratories Antimicrobial for in-vitro diagnostic kits
CA1336090C (en) 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
US5286723A (en) 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
PL166381B1 (pl) 1989-08-16 1995-05-31 Pfizer Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
EP0541086A1 (en) 1991-11-08 1993-05-12 Kaken Pharmaceutical Co., Ltd. Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7
WO1993025545A1 (en) 1992-06-09 1993-12-23 Korea Research Institute Of Chemical Technology Novel quinoline derivatives and processes for preparing the same
DK0688772T3 (da) * 1994-06-16 1999-11-01 Lg Chemical Ltd Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling
US5776944A (en) 1994-06-16 1998-07-07 Lg Chemical Ltd. 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
WO1996012704A1 (fr) 1994-10-20 1996-05-02 Wakunaga Seiyaku Kabushiki Kaisha Nouveau derive de pyridone-carboxylate, ou sel de celui-ci, et antibacterien le contenant comme principe actif
WO1996023775A1 (fr) 1995-01-30 1996-08-08 Wakunaga Seiyaku Kabushiki Kaisha Nouveaux derives d'acide pyridonecarboxylique ou de ses sels et agent antibacterien contenant ces derives en tant qu'ingredient actif
JP3145715B2 (ja) 1995-06-06 2001-03-12 ファイザー・インコーポレーテッド 無水7−([1α,5α,6α]−6−アミノ−3−アザビシクロ[3.1.0]ヘキサ−3−イル)−6−フルオロ−1−(2,4−ジフルオロフェニル)−1,4−ジヒドロ−4−オキソ−1,8−ナフチリディン−3−カルボン酸メタンスルホン酸塩の新規な結晶形態
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KR100286874B1 (ko) 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process

Also Published As

Publication number Publication date
HUP0000728A2 (hu) 2000-09-28
SA98181055B1 (ar) 2006-10-11
SK123699A3 (en) 2000-08-14
CZ288715B6 (cs) 2001-08-15
JP4781614B2 (ja) 2011-09-28
WO1998042705A1 (en) 1998-10-01
US20150291585A1 (en) 2015-10-15
AU6636698A (en) 1998-10-20
DE69821147T2 (de) 2004-11-11
EP1179533A2 (en) 2002-02-13
AU726634B2 (en) 2000-11-16
NO312515B1 (no) 2002-05-21
JP2009051851A (ja) 2009-03-12
ATE257836T1 (de) 2004-01-15
US20170253588A1 (en) 2017-09-07
HU225412B1 (en) 2006-11-28
SI1179533T1 (en) 2004-04-30
ES2213669T3 (es) 2004-09-01
MY137653A (en) 2009-02-27
HUP0600401A3 (en) 2010-05-28
US20100240694A1 (en) 2010-09-23
EP1179533B1 (en) 2004-01-14
BG103750A (en) 2000-06-30
NZ337748A (en) 2001-03-30
HU0600401D0 (en) 2006-07-28
DK0981527T3 (da) 2003-09-01
ES2198697T3 (es) 2004-02-01
US20160264569A1 (en) 2016-09-15
KR100266499B1 (ko) 2000-12-01
ZA982335B (en) 1999-11-23
KR19980080504A (ko) 1998-11-25
JP3759962B2 (ja) 2006-03-29
DK1179533T3 (da) 2004-05-03
IL131812A0 (en) 2001-03-19
CA2283671A1 (en) 1998-10-01
DE69814378T2 (de) 2004-02-26
UA56218C2 (uk) 2003-05-15
US20110312987A1 (en) 2011-12-22
JP2000510484A (ja) 2000-08-15
HK1026698A1 (en) 2000-12-22
HU227536B1 (en) 2011-08-29
IS7952A (is) 2005-07-21
EA199900855A1 (ru) 2000-04-24
IN188178B (hu) 2002-08-31
CN1251101A (zh) 2000-04-19
DE69821147D1 (de) 2004-02-19
CZ288673B6 (cs) 2001-08-15
AR012125A1 (es) 2000-09-27
CN1131229C (zh) 2003-12-17
IS2095B (is) 2006-04-12
US20130065917A1 (en) 2013-03-14
SK284107B6 (sk) 2004-09-08
DE69814378D1 (de) 2003-06-12
NO994595D0 (no) 1999-09-21
PE67999A1 (es) 1999-09-30
CZ328299A3 (cs) 2000-02-16
US20140187576A1 (en) 2014-07-03
SI0981527T1 (en) 2003-10-31
EP0981527B1 (en) 2003-05-07
EP1179533A3 (en) 2002-03-20
US7700617B2 (en) 2010-04-20
HUP0000728A3 (en) 2002-12-28
PL191815B1 (pl) 2006-07-31
ATE239724T1 (de) 2003-05-15
JP2004002413A (ja) 2004-01-08
AP1331A (en) 2004-11-26
US20090182006A1 (en) 2009-07-16
EP0981527A1 (en) 2000-03-01
US20080039488A1 (en) 2008-02-14
CA2283671C (en) 2003-09-16
NO994595L (no) 1999-09-21
IS5181A (is) 1999-09-14
PT981527E (pt) 2003-09-30
BR9808290A (pt) 2000-05-16
IS2093B (is) 2006-04-12
IL131812A (en) 2006-04-10
TR199902313T2 (xx) 1999-12-21
PL335812A1 (en) 2000-05-22
EA001674B1 (ru) 2001-06-25
AP9901649A0 (en) 1999-09-30
BG63972B1 (bg) 2003-08-29
ID22681A (id) 1999-12-09
MA24500A1 (fr) 1998-10-01
PT1179533E (pt) 2004-05-31
OA11161A (en) 2003-04-25

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