SI0981527T1 - Salt of naphthyridine carboxylic acid derivative - Google Patents

Salt of naphthyridine carboxylic acid derivative

Info

Publication number: SI0981527T1
Authority: SI; Slovenia
Prior art keywords: salt; carboxylic acid; acid derivative; naphthyridine carboxylic; naphthyridine
Prior art date: 1997-03-21

Application number

SI9830418T

Other languages

English (en)

Slovenian (sl)

Inventor

Ae Ri Kim

Jin Hwa Lee

Ki Sook Park

Jong Ryoo Choi

Tae Hee Lee

Jay Hyok Chang

Do Hyun Nam

Hoon Choi

Original Assignee

Lg Life Sciences Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-21

Filing date

1998-03-20

Publication date

2003-10-31

1998-03-20 Application filed by Lg Life Sciences Ltd. filed Critical Lg Life Sciences Ltd.

2003-10-31 Publication of SI0981527T1 publication Critical patent/SI0981527T1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SI9830418T 1997-03-21 1998-03-20 Salt of naphthyridine carboxylic acid derivative SI0981527T1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
KR19970009840		1997-03-21
PCT/KR1998/000051 WO1998042705A1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative
EP98908300A EP0981527B1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative

Publications (1)

Publication Number	Publication Date
SI0981527T1 true SI0981527T1 (en)	2003-10-31

Family

ID=19500439

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SI9830595T SI1179533T1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative
SI9830418T SI0981527T1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SI9830595T SI1179533T1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative

Country Status (39)

Country	Link
US (9)	US7700617B2 (xx)
EP (2)	EP1179533B1 (xx)
JP (3)	JP3759962B2 (xx)
KR (1)	KR100266499B1 (xx)
CN (1)	CN1131229C (xx)
AP (1)	AP1331A (xx)
AR (1)	AR012125A1 (xx)
AT (2)	ATE257836T1 (xx)
AU (1)	AU726634B2 (xx)
BG (1)	BG63972B1 (xx)
BR (1)	BR9808290A (xx)
CA (1)	CA2283671C (xx)
CZ (2)	CZ288673B6 (xx)
DE (2)	DE69814378T2 (xx)
DK (2)	DK1179533T3 (xx)
DZ (1)	DZ2448A1 (xx)
EA (1)	EA001674B1 (xx)
ES (2)	ES2213669T3 (xx)
HK (1)	HK1026698A1 (xx)
HU (2)	HU227536B1 (xx)
ID (1)	ID22681A (xx)
IL (2)	IL131812A0 (xx)
IN (1)	IN188178B (xx)
IS (2)	IS2093B (xx)
MA (1)	MA24500A1 (xx)
MY (1)	MY137653A (xx)
NO (1)	NO312515B1 (xx)
NZ (1)	NZ337748A (xx)
OA (1)	OA11161A (xx)
PE (1)	PE67999A1 (xx)
PL (1)	PL191815B1 (xx)
PT (2)	PT1179533E (xx)
SA (1)	SA98181055B1 (xx)
SI (2)	SI1179533T1 (xx)
SK (1)	SK284107B6 (xx)
TR (1)	TR199902313T2 (xx)
UA (1)	UA56218C2 (xx)
WO (1)	WO1998042705A1 (xx)
ZA (1)	ZA982335B (xx)

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GB9820405D0 (en) *	1998-09-18	1998-11-11	Smithkline Beecham Plc	Process
CN1352552A (zh) *	1999-03-19	2002-06-05	克诺尔股份有限公司	关于骨关节炎的治疗
US6331550B1 (en)	1999-06-29	2001-12-18	Smithkline Beecham Corporation	Methods of use of quinolone compounds against anaerobic pathogenic bacteria
US6262071B1 (en)	1999-06-29	2001-07-17	Smithkline Beecham Corporation	Methods of use of antimicrobial compounds against pathogenic amycoplasma bacteria
CA2282066C (en)	1999-06-29	2010-09-07	Smithkline Beecham Corporation	Methods of use of quinolone compounds against atypical upper respiratory pathogenic bacteria
US6803376B1 (en)	1999-06-29	2004-10-12	Smithkline Beecham Corporation	Method of use of quinolone compounds against pneumococcal and haemophilus bacteria
GB9920919D0 (en)	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel compound
GB9920917D0 (en) *	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel process
JP2001097891A (ja) *	1999-09-24	2001-04-10	Smithkline Beecham Corp	呼吸器系病原菌に対するフルオロキノロン化合物の使用法
EP1242079A4 (en) *	1999-09-22	2003-01-22	Smithkline Beecham	Methods of anti-bacterial use of fluoroquinolonic compounds
JP2001097864A (ja) *	1999-09-24	2001-04-10	Smithkline Beecham Corp	呼吸管および尿路病原性細菌に対するフルオロキノリン化合物の使用方法
JP2001097863A (ja) *	1999-09-24	2001-04-10	Smithkline Beecham Corp	嫌気性病原菌に対するフルオロキノロン化合物の使用法
GR1003520B (el) *	1999-09-22	2001-01-22	Smithkline Beecham Plc	Μεθοδος χρησης ενωσεων φλουοροκινολονης εναντια σε νοσοκομειακα αρνητικα κατα gramμ παθογενων βακτηριδιων
GR1003521B (el) *	1999-09-23	2001-01-22	Smithkline Beecham Plc	Μεθοδοι χρησεως ενωσεων φλουοροκινολονης εναντια κατα gram θετικων παθογονων βακτηριδιων
KR20010091379A (ko) *	2000-03-15	2001-10-23	성재갑	7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
US7199242B2 (en)	2001-08-02	2007-04-03	Lg Life Sciences Limited	Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one and/or 4-aminomethylene-pyrrolidin-3-alkoxyimino derivatives and/or gemifloxacin or a salt thereof
DE60222298T2 (de) *	2001-11-30	2008-01-03	Lg Life Sciences Ltd.	Verfahren zur behandlung von bakteriellen infektionen mit gemifloxacin oder einem seiner salze und einem beta-lactam-antibiotikum
KR100517638B1 (ko) *	2002-04-08	2005-09-28	주식회사 엘지생명과학	게미플록사신 산염의 새로운 제조방법
AR043880A1 (es) *	2003-04-22	2005-08-17	Solvay Pharm Gmbh	Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas
EP1891037A1 (en) *	2005-06-15	2008-02-27	Hetero Drugs Limited	Gemifloxacin process and polymorphs
JP5384119B2 (ja) *	2006-03-07	2014-01-08	ウォックハートリミテッド	ベンゾキノリジン−２−カルボン酸のプロドラッグ
WO2010001408A2 (en) *	2008-06-06	2010-01-07	Matrix Laboratories Ltd.	Novel polymorphic forms of gemifloxacin mesylate
WO2010146594A1 (en) *	2009-06-16	2010-12-23	Hetero Research Foundation	Novel polymorphs of gemifloxacin mesylate
EP2491921A1 (en) *	2011-02-25	2012-08-29	Deva Holding Anonim Sirketi	Conservation of anhydrous form of gemifloxacin
AU2013226361B2 (en) *	2012-02-27	2017-09-21	Bristol-Myers Squibb Company	N- (5S, 6S, 9R) - 5 -amino- 6 - (2, 3 - difluorophenyl) -6, 7, 8, 9 - tetrahydro - 5H - cyclohepta [b] pyridin-9 -yl- 4 - (2 - oxo-2, 3 - dihydro - 1H- imidazo [4, 5 -b] pyridin - 1 - yl) piperidine - 1 - carboxylate, hemisulfate salt
CZ2016104A3 (cs) *	2016-02-24	2017-09-06	Zentiva, K.S.	Krystalické modifikace solí methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}fenyl)amino](fenyl)methyliden}-2-oxo-2,3-dihydro-1H-indol-6-karboxylátu a způsoby jejich přípravy

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AR223983A1 (es)	1978-08-25	1981-10-15	Dainippon Pharmaceutical Co	Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
HU188181B (en)	1981-06-11	1986-03-28	Warner-Lambert Co,Us	Process for producing salts of naphtiridine and quinoline compounds of antimicrobial activity
IN162769B (xx)	1984-11-13	1988-07-09	Kyorin Seiyaku Kk
NZ222047A (en)	1986-10-08	1991-01-29	Bristol Myers Co	Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (ja)	1987-10-13	1989-04-18	Shionogi & Co Ltd	オキシムまたはヒドロキシアミン誘導体系抗菌剤
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KR100286874B1 (ko) *	1998-03-04	2001-04-16	성재갑	보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
GB9820405D0 (en)	1998-09-18	1998-11-11	Smithkline Beecham Plc	Process

1998
- 1998-03-17 MA MA25001A patent/MA24500A1/fr unknown
- 1998-03-18 DZ DZ980058A patent/DZ2448A1/xx active
- 1998-03-19 ZA ZA9802335A patent/ZA982335B/xx unknown
- 1998-03-20 IL IL13181298A patent/IL131812A0/xx active IP Right Grant
- 1998-03-20 SK SK1236-99A patent/SK284107B6/sk not_active IP Right Cessation
- 1998-03-20 EP EP01203507A patent/EP1179533B1/en not_active Expired - Lifetime
- 1998-03-20 DK DK01203507T patent/DK1179533T3/da active
- 1998-03-20 SI SI9830595T patent/SI1179533T1/ unknown
- 1998-03-20 EA EA199900855A patent/EA001674B1/ru not_active IP Right Cessation
- 1998-03-20 ID IDW991044A patent/ID22681A/id unknown
- 1998-03-20 CN CN98803576A patent/CN1131229C/zh not_active Expired - Lifetime
- 1998-03-20 AU AU66366/98A patent/AU726634B2/en not_active Expired
- 1998-03-20 CZ CZ19993282A patent/CZ288673B6/cs not_active IP Right Cessation
- 1998-03-20 PE PE1998000202A patent/PE67999A1/es not_active Application Discontinuation
- 1998-03-20 AT AT01203507T patent/ATE257836T1/de active
- 1998-03-20 NZ NZ337748A patent/NZ337748A/xx not_active IP Right Cessation
- 1998-03-20 JP JP54550098A patent/JP3759962B2/ja not_active Expired - Lifetime
- 1998-03-20 AT AT98908300T patent/ATE239724T1/de active
- 1998-03-20 CA CA002283671A patent/CA2283671C/en not_active Expired - Lifetime
- 1998-03-20 TR TR1999/02313T patent/TR199902313T2/xx unknown
- 1998-03-20 HU HU0600401A patent/HU227536B1/hu unknown
- 1998-03-20 KR KR1019980009717A patent/KR100266499B1/ko active IP Right Grant
- 1998-03-20 PT PT01203507T patent/PT1179533E/pt unknown
- 1998-03-20 UA UA99095186A patent/UA56218C2/uk unknown
- 1998-03-20 SI SI9830418T patent/SI0981527T1/xx unknown
- 1998-03-20 PL PL335812A patent/PL191815B1/pl unknown
- 1998-03-20 PT PT98908300T patent/PT981527E/pt unknown
- 1998-03-20 IL IL131812A patent/IL131812A/en not_active IP Right Cessation
- 1998-03-20 DE DE69814378T patent/DE69814378T2/de not_active Expired - Lifetime
- 1998-03-20 WO PCT/KR1998/000051 patent/WO1998042705A1/en active IP Right Grant
- 1998-03-20 DE DE69821147T patent/DE69821147T2/de not_active Expired - Lifetime
- 1998-03-20 AP APAP/P/1999/001649A patent/AP1331A/en active
- 1998-03-20 ES ES01203507T patent/ES2213669T3/es not_active Expired - Lifetime
- 1998-03-20 ES ES98908300T patent/ES2198697T3/es not_active Expired - Lifetime
- 1998-03-20 DK DK98908300T patent/DK0981527T3/da active
- 1998-03-20 BR BR9808290-6A patent/BR9808290A/pt not_active Application Discontinuation
- 1998-03-20 EP EP98908300A patent/EP0981527B1/en not_active Expired - Lifetime
- 1998-03-20 HU HU0000728A patent/HU225412B1/hu unknown
- 1998-03-20 AR ARP980101268A patent/AR012125A1/es active IP Right Grant
- 1998-03-21 MY MYPI98001236A patent/MY137653A/en unknown
- 1998-03-23 IN IN727DE1998 patent/IN188178B/en unknown
- 1998-03-25 SA SA98181055A patent/SA98181055B1/ar unknown
1999
- 1999-09-14 IS IS5181A patent/IS2093B/is unknown
- 1999-09-20 OA OA9900213A patent/OA11161A/fr unknown
- 1999-09-21 BG BG103750A patent/BG63972B1/bg unknown
- 1999-09-21 NO NO19994595A patent/NO312515B1/no not_active IP Right Cessation
2000
- 2000-08-30 HK HK00105435A patent/HK1026698A1/xx not_active IP Right Cessation
- 2000-10-03 CZ CZ20003641A patent/CZ288715B6/cs not_active IP Right Cessation
2003
- 2003-05-07 JP JP2003128650A patent/JP4781614B2/ja not_active Expired - Lifetime
2005
- 2005-07-21 IS IS7952A patent/IS2095B/is unknown
2006
- 2006-12-07 US US11/635,069 patent/US7700617B2/en not_active Expired - Fee Related
2008
- 2008-10-14 JP JP2008265345A patent/JP2009051851A/ja not_active Withdrawn
2009
- 2009-01-09 US US12/318,845 patent/US20090182006A1/en not_active Abandoned
2010
- 2010-06-02 US US12/791,957 patent/US20100240694A1/en not_active Abandoned
2011
- 2011-04-11 US US13/083,685 patent/US20110312987A1/en not_active Abandoned
2012
- 2012-06-26 US US13/533,383 patent/US20130065917A1/en not_active Abandoned
2013
- 2013-10-25 US US14/063,117 patent/US20140187576A1/en not_active Abandoned
2015
- 2015-02-13 US US14/621,689 patent/US20150291585A1/en not_active Abandoned
2016
- 2016-01-15 US US14/996,765 patent/US20160264569A1/en not_active Abandoned
2017
- 2017-01-20 US US15/411,030 patent/US20170253588A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CZ328299A3 (cs)	2000-02-16
NO994595D0 (no)	1999-09-21
CN1131229C (zh)	2003-12-17
US20150291585A1 (en)	2015-10-15
ATE257836T1 (de)	2004-01-15
CZ288673B6 (cs)	2001-08-15
IN188178B (xx)	2002-08-31
CA2283671C (en)	2003-09-16
IS2095B (is)	2006-04-12
SK284107B6 (sk)	2004-09-08
NZ337748A (en)	2001-03-30
MA24500A1 (fr)	1998-10-01
NO312515B1 (no)	2002-05-21
AP1331A (en)	2004-11-26
PL335812A1 (en)	2000-05-22
PT981527E (pt)	2003-09-30
TR199902313T2 (xx)	1999-12-21
ZA982335B (en)	1999-11-23
PL191815B1 (pl)	2006-07-31
SI1179533T1 (en)	2004-04-30
MY137653A (en)	2009-02-27
UA56218C2 (uk)	2003-05-15
JP2009051851A (ja)	2009-03-12
JP2004002413A (ja)	2004-01-08
EA001674B1 (ru)	2001-06-25
IS2093B (is)	2006-04-12
DE69814378T2 (de)	2004-02-26
JP3759962B2 (ja)	2006-03-29
US20140187576A1 (en)	2014-07-03
EA199900855A1 (ru)	2000-04-24
AR012125A1 (es)	2000-09-27
OA11161A (en)	2003-04-25
US20090182006A1 (en)	2009-07-16
HK1026698A1 (en)	2000-12-22
DE69814378D1 (de)	2003-06-12
DK1179533T3 (da)	2004-05-03
AU726634B2 (en)	2000-11-16
HUP0600401A3 (en)	2010-05-28
DE69821147T2 (de)	2004-11-11
EP1179533A2 (en)	2002-02-13
EP0981527A1 (en)	2000-03-01
JP2000510484A (ja)	2000-08-15
PE67999A1 (es)	1999-09-30
IL131812A0 (en)	2001-03-19
CZ288715B6 (cs)	2001-08-15
US20130065917A1 (en)	2013-03-14
KR100266499B1 (ko)	2000-12-01
US20160264569A1 (en)	2016-09-15
AP9901649A0 (en)	1999-09-30
BG63972B1 (bg)	2003-08-29
ES2213669T3 (es)	2004-09-01
CA2283671A1 (en)	1998-10-01
DZ2448A1 (fr)	2003-01-11
DE69821147D1 (de)	2004-02-19
KR19980080504A (ko)	1998-11-25
JP4781614B2 (ja)	2011-09-28
NO994595L (no)	1999-09-21
DK0981527T3 (da)	2003-09-01
ID22681A (id)	1999-12-09
IS5181A (is)	1999-09-14
BR9808290A (pt)	2000-05-16
US20170253588A1 (en)	2017-09-07
AU6636698A (en)	1998-10-20
US7700617B2 (en)	2010-04-20
SA98181055B1 (ar)	2006-10-11
ATE239724T1 (de)	2003-05-15
IL131812A (en)	2006-04-10
CN1251101A (zh)	2000-04-19
HUP0000728A3 (en)	2002-12-28
HU225412B1 (en)	2006-11-28
ES2198697T3 (es)	2004-02-01
EP1179533B1 (en)	2004-01-14
BG103750A (en)	2000-06-30
EP1179533A3 (en)	2002-03-20
EP0981527B1 (en)	2003-05-07
HU0600401D0 (en)	2006-07-28
SK123699A3 (en)	2000-08-14
HU227536B1 (en)	2011-08-29
US20110312987A1 (en)	2011-12-22
WO1998042705A1 (en)	1998-10-01
US20080039488A1 (en)	2008-02-14
IS7952A (is)	2005-07-21
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US20100240694A1 (en)	2010-09-23
PT1179533E (pt)	2004-05-31

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