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DOP2017000055A - Tratamientos médicos a base de anamorelina - Google Patents

Tratamientos médicos a base de anamorelina

Info

Publication number
DOP2017000055A
DOP2017000055A DO2017000055A DO2017000055A DOP2017000055A DO P2017000055 A DOP2017000055 A DO P2017000055A DO 2017000055 A DO2017000055 A DO 2017000055A DO 2017000055 A DO2017000055 A DO 2017000055A DO P2017000055 A DOP2017000055 A DO P2017000055A
Authority
DO
Dominican Republic
Prior art keywords
anamorelin
anamoreline
medical treatments
based medical
cancer
Prior art date
Application number
DO2017000055A
Other languages
English (en)
Inventor
Mann William
Friend John
Polvino William
Allen Suzan
Lu Ming
Duus Elizabeth
Giorgino Ruben
Baroni Enrico
Original Assignee
Helsinn Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55436476&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2017000055(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Helsinn Healthcare Sa filed Critical Helsinn Healthcare Sa
Publication of DOP2017000055A publication Critical patent/DOP2017000055A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Se describen procedimientos para la fabricación de medicamentos útiles para el tratamiento de afecciones relacionadas con el cáncer usando anamorelina. La modalidad principal se relaciona con la afección única de pacientes que la definen mediante el tratamiento de la caquexia en un paciente humano con cáncer, que comprende el uso de una cantidad terapéuticamente efectiva de anamorelina durante un período terapéuticamente efectivo, y la sorprendente capacidad observada de la anamorelina de aumentar la masa corporal magra de esta población.
DO2017000055A 2014-09-04 2017-03-03 Tratamientos médicos a base de anamorelina DOP2017000055A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462045976P 2014-09-04 2014-09-04

Publications (1)

Publication Number Publication Date
DOP2017000055A true DOP2017000055A (es) 2017-08-15

Family

ID=55436476

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2017000055A DOP2017000055A (es) 2014-09-04 2017-03-03 Tratamientos médicos a base de anamorelina

Country Status (44)

Country Link
US (5) US9675600B2 (es)
EP (2) EP3590338A3 (es)
JP (3) JP6356907B2 (es)
KR (3) KR102234319B1 (es)
CN (5) CN109172575A (es)
AP (1) AP2017009772A0 (es)
AR (1) AR103118A1 (es)
AU (1) AU2015312231B2 (es)
BR (1) BR112017003552A2 (es)
CA (1) CA2959158A1 (es)
CL (1) CL2017000494A1 (es)
CO (1) CO2017003263A2 (es)
CR (1) CR20170121A (es)
CY (1) CY1122746T1 (es)
DK (1) DK3188599T3 (es)
DO (1) DOP2017000055A (es)
EA (1) EA035578B1 (es)
EC (1) ECSP17019893A (es)
ES (1) ES2761777T3 (es)
GE (1) GEP20186939B (es)
HR (1) HRP20192345T1 (es)
HU (1) HUE046894T2 (es)
IL (1) IL250692B (es)
JO (1) JO3541B1 (es)
LT (1) LT3188599T (es)
MA (1) MA40607B1 (es)
MD (1) MD4710C1 (es)
ME (1) ME03597B (es)
MX (1) MX361741B (es)
MY (1) MY187167A (es)
NI (1) NI201700024A (es)
PE (1) PE20171109A1 (es)
PH (1) PH12017500392A1 (es)
PL (1) PL3188599T3 (es)
PT (1) PT3188599T (es)
RS (1) RS59751B1 (es)
SG (1) SG11201701567UA (es)
SI (1) SI3188599T1 (es)
SV (1) SV2017005400A (es)
TN (1) TN2017000040A1 (es)
TW (1) TWI639429B (es)
UA (1) UA120765C2 (es)
UY (1) UY36286A (es)
WO (1) WO2016036598A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014159609A1 (en) 2013-03-14 2014-10-02 Allergen Research Corporation Peanut formulations and uses thereof
CN109172575A (zh) 2014-09-04 2019-01-11 赫尔森保健股份公司 基于阿拉莫林的药物治疗
AU2020276213A1 (en) 2019-05-10 2021-10-28 Société des Produits Nestlé S.A. Methods for improving the quality of life of a patient with a peanut allergy
WO2021038519A1 (en) 2019-08-30 2021-03-04 Helsinn Healthcare Sa Methods of manufacturing anamorelin tablets having improved stability
JPWO2021079978A1 (es) 2019-10-24 2021-04-29
WO2023042158A1 (en) * 2021-09-17 2023-03-23 Helsinn Healthcare Sa Methods of determining and providing clinically meaningful improvements on patient reported outcomes in anorexia / cachexia patients

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303620B1 (en) 1998-05-11 2001-10-16 Novo Nordisk A/S Compounds with growth hormone releasing properties
ECSP993021A (es) 1999-06-16 1999-08-12 Combinaciones terapeuticas para la fragilidad musculoesqueletica
ECSP993020A (es) 1999-06-16 1999-08-12 Terapia de combinacion para la fragilidad musculoesqueletica
US20010020012A1 (en) 2000-02-01 2001-09-06 Andersen Maibritt Bansholm Use of compounds for the regulation of food intake
WO2005014032A2 (en) * 2003-08-06 2005-02-17 Gastrotech Pharma A/S Use of secretagogues like ghrelin in cancer cachexia and for stimulating appetite
CN1863550A (zh) * 2003-08-06 2006-11-15 加斯特罗泰克药物公司 促分泌素样生长素释放肽在癌症恶病质中以及在刺激食欲方面的应用
KR20070010151A (ko) 2004-03-30 2007-01-22 사파이어 세라퓨틱스, 인크. 성장 호르몬 분비촉진제를 이용하여 c-반응성 단백질을감소시키는 방법
MXPA06015003A (es) * 2004-06-29 2007-08-07 Sapphire Therapeutics Inc Formas cristalinas de 1,2,2-trimetilhidrazida de acido (3r)-1-(2-metilalanil-d-triptofil)-3-(fenilmetil)-3- piperidincarboxilico.
AU2008216789A1 (en) * 2007-02-13 2008-08-21 Helsinn Therapeutics (U.S.), Inc. Method of treating cell proliferative disorders using growth hormone secretagogues
TWI429436B (zh) 2007-04-10 2014-03-11 Helsinn Therapeutics Us Inc 使用生長激素促泌素治療或預防嘔吐之方法
JO3353B1 (ar) * 2012-04-20 2019-03-13 Ono Pharmaceutical Co شكل صلب معزول من أحادي هيدروكلوريد أناموريلين بنسبة مولارية منخفضة من الكلوريد: أناموريلين ومحتوى منخفض من مذيب عضوي متبقي
US20150099709A1 (en) * 2012-05-25 2015-04-09 Raqualia Pharma Inc. Ghrelin receptor agonists for the treatment of achlorhydria
CN109172575A (zh) 2014-09-04 2019-01-11 赫尔森保健股份公司 基于阿拉莫林的药物治疗

Also Published As

Publication number Publication date
MX2017002825A (es) 2017-09-28
CN107205389A (zh) 2017-09-26
US9675600B2 (en) 2017-06-13
US20240024303A1 (en) 2024-01-25
KR20170047372A (ko) 2017-05-04
BR112017003552A2 (pt) 2017-12-05
KR20180085047A (ko) 2018-07-25
UY36286A (es) 2016-02-29
AU2015312231B2 (en) 2017-10-19
WO2016036598A1 (en) 2016-03-10
SI3188599T1 (sl) 2020-02-28
US20210093627A1 (en) 2021-04-01
NZ729673A (en) 2023-09-29
ECSP17019893A (es) 2017-05-31
PL3188599T3 (pl) 2020-06-01
EP3590338A2 (en) 2020-01-08
PE20171109A1 (es) 2017-08-07
MD4710C1 (ro) 2021-04-30
EP3188599A1 (en) 2017-07-12
AP2017009772A0 (en) 2017-02-28
KR101881264B1 (ko) 2018-07-23
HRP20192345T1 (hr) 2020-03-20
TN2017000040A1 (en) 2018-07-04
US20170296526A1 (en) 2017-10-19
MX361741B (es) 2018-12-14
CN109172575A (zh) 2019-01-11
US11723902B2 (en) 2023-08-15
EP3188599B1 (en) 2019-10-02
IL250692B (en) 2019-05-30
PT3188599T (pt) 2020-01-15
US10894041B2 (en) 2021-01-19
PH12017500392B1 (en) 2017-07-17
LT3188599T (lt) 2019-12-10
US20160067236A1 (en) 2016-03-10
CY1122746T1 (el) 2021-03-12
ME03597B (me) 2020-07-20
MD20170025A2 (ro) 2017-07-31
CN107375285A (zh) 2017-11-24
IL250692A0 (en) 2017-04-30
CL2017000494A1 (es) 2017-09-15
KR102307275B1 (ko) 2021-09-30
SV2017005400A (es) 2017-04-20
ES2761777T3 (es) 2020-05-21
CR20170121A (es) 2017-07-17
NI201700024A (es) 2017-07-18
RS59751B1 (sr) 2020-02-28
MY187167A (en) 2021-09-07
JP6923486B2 (ja) 2021-08-18
EP3188599A4 (en) 2017-10-11
KR102234319B1 (ko) 2021-04-01
MD4710B1 (ro) 2020-09-30
CO2017003263A2 (es) 2017-07-28
JP2018154655A (ja) 2018-10-04
CN113577074A (zh) 2021-11-02
JP2021080281A (ja) 2021-05-27
JP7044918B2 (ja) 2022-03-30
JP6356907B2 (ja) 2018-07-11
AU2015312231A1 (en) 2017-03-23
KR20210035923A (ko) 2021-04-01
MA40607B1 (fr) 2019-11-29
CN113577073A (zh) 2021-11-02
AR103118A1 (es) 2017-04-19
DK3188599T3 (da) 2019-11-25
EA201790352A1 (ru) 2017-07-31
JP2017526695A (ja) 2017-09-14
US10278964B2 (en) 2019-05-07
TW201613587A (en) 2016-04-16
CA2959158A1 (en) 2016-03-10
EP3590338A3 (en) 2020-03-18
EA035578B1 (ru) 2020-07-09
GEP20186939B (en) 2018-12-25
UA120765C2 (uk) 2020-02-10
HUE046894T2 (hu) 2020-04-28
SG11201701567UA (en) 2017-03-30
TWI639429B (zh) 2018-11-01
US20190175574A1 (en) 2019-06-13
JO3541B1 (ar) 2020-07-05
PH12017500392A1 (en) 2017-07-17

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