DK552476A - GLUCOSAMINE DERIVATIVES AND PROCEDURES - Google Patents

GLUCOSAMINE DERIVATIVES AND PROCEDURES

Info

Publication number: DK552476A
Authority: DK; Denmark
Prior art keywords: procedures; glucosamine derivatives; glucosamine; derivatives
Prior art date: 1975-12-10

Application number

DK552476A

Other languages

Danish (da)

Other versions

DK154654B (en

DK154654C (en

Inventor

G Baschang

A Hartmann

J Stanek

A Sele

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-12-10

Filing date

1976-12-09

Publication date

1977-06-11

1976-12-09 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1977-06-11 Publication of DK552476A publication Critical patent/DK552476A/en

1988-12-05 Publication of DK154654B publication Critical patent/DK154654B/en

1989-05-08 Application granted granted Critical

1989-05-08 Publication of DK154654C publication Critical patent/DK154654C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Crystallography & Structural Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK552476A 1975-12-10 1976-12-09 METHOD OF ANALOGUE FOR THE PREPARATION OF IMMUNO MODULATING 2-OE2-ACYLAMINO-2-DESOXY- (D) -GLUCOSYL-3-OAA-ALKANCARBOXYL ACID Peptide DERIVATIVES OR PHARMACEUTICAL ACCEPTABLE ACCEPTABLE ACCEPTABLE DK154654C (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH1604275A CH613709A5 (en)	1975-12-10	1975-12-10	Process for the preparation of glucosamine derivatives
CH1604275		1975-12-10

Publications (3)

Publication Number	Publication Date
DK552476A true DK552476A (en)	1977-06-11
DK154654B DK154654B (en)	1988-12-05
DK154654C DK154654C (en)	1989-05-08

Family

ID=4414012

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK552476A DK154654C (en)	1975-12-10	1976-12-09	METHOD OF ANALOGUE FOR THE PREPARATION OF IMMUNO MODULATING 2-OE2-ACYLAMINO-2-DESOXY- (D) -GLUCOSYL-3-OAA-ALKANCARBOXYL ACID Peptide DERIVATIVES OR PHARMACEUTICAL ACCEPTABLE ACCEPTABLE ACCEPTABLE

Country Status (30)

Country	Link
JP (1)	JPS5273820A (en)
AR (2)	AR224091A1 (en)
AT (1)	AT365607B (en)
AU (1)	AU508764B2 (en)
BE (1)	BE849214A (en)
CA (1)	CA1262400A (en)
CH (2)	CH613709A5 (en)
CS (4)	CS205027B2 (en)
DD (1)	DD129781A5 (en)
DE (1)	DE2655500A1 (en)
DK (1)	DK154654C (en)
ES (2)	ES454118A1 (en)
FI (1)	FI64164C (en)
FR (1)	FR2361902A1 (en)
GB (1)	GB1570625A (en)
GR (1)	GR61647B (en)
HK (1)	HK32883A (en)
HU (1)	HU177970B (en)
IE (1)	IE44190B1 (en)
IL (1)	IL51076A (en)
MY (1)	MY8400123A (en)
NL (1)	NL7613666A (en)
NO (1)	NO144850C (en)
NZ (1)	NZ182837A (en)
PL (4)	PL110353B1 (en)
PT (1)	PT65946B (en)
SE (1)	SE445923B (en)
SG (1)	SG11083G (en)
SU (3)	SU660589A3 (en)
ZA (1)	ZA767333B (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4186194A (en) *	1973-10-23	1980-01-29	Agence Nationale De Valorisation De La Recherche (Anvar)	Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) *	1974-10-22	1983-01-25	Agence Nationale De Valorisation	Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
GB1571133A (en) *	1976-04-26	1980-07-09	Syntex Inc	Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof
EP0002677B1 (en)	1977-12-02	1982-10-13	Takeda Chemical Industries, Ltd.	Glucosamine-peptide derivatives and their pharmaceutical compositions
CA1138436A (en) *	1978-02-24	1982-12-28	Gerhard Baschang	Process for the manufacture of novel antigens
US4397844A (en) *	1978-02-24	1983-08-09	Ciba-Geigy Corporation	Antigen derivatives and processes for their preparation
FR2420545A1 (en) *	1978-03-20	1979-10-19	Anvar	NEW ESTERS OF N-ACETYL-MURAMYL-AMINOACYL-GLUTAMIC ACID OR SUBSTITUTION DERIVATIVES THEREOF WITH ANTI-INFECTIOUS PROPERTIES AND / OR IMMUNOLOGICAL ADJUVANTS
FR2442241A2 (en) *	1978-03-20	1980-06-20	Anvar	NOVEL ESTER COMPOUNDS OF MURAMYL-PEPTIDE, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, IN PARTICULAR IN THE FORM OF LIPOSOMES
FR2428050A1 (en) *	1978-06-05	1980-01-04	Anvar	OLIGOMERS OF MURAMYL-PEPTIDE COMPOUNDS AND DRUGS CONTAINING THEM
FR2428051A1 (en) *	1978-06-05	1980-01-04	Anvar	NOVEL MURAMYL-PEPTIDE COMPOUNDS AND MEDICAMENTS CONTAINING THEM
FR2446292A1 (en) *	1979-01-12	1980-08-08	Anvar	MURAMYL-PEPTIDES FIXED ON PEPTIDE POLYMERS AND MEDICAMENTS CONTAINING THEM
US4256735A (en) *	1979-01-29	1981-03-17	Merck & Co., Inc.	Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (en)	1979-02-20	1980-09-19	Anvar	NOVEL MURAMYL-PEPTIDES SUBSTITUTED ON PEPTIDE NITROGEN AND MEDICAMENTS CONTAINING THEM
JPS55111499A (en) *	1979-02-21	1980-08-28	Takeda Chem Ind Ltd	Glucosamine derivative and its preparation
JPS5618996A (en) *	1979-06-21	1981-02-23	Dai Ichi Seiyaku Co Ltd	Muramyldipeptide derivative
FI75578C (en)	1979-07-25	1988-07-11	Ciba Geigy Ag	Analogous procedure for the preparation of pharmacologically acting lipophilic a phosphatidylmuramyl peptides.
JPS5649396A (en) *	1979-09-28	1981-05-02	Dai Ichi Seiyaku Co Ltd	Novel muramyldipeptide derivative
DE3070457D1 (en) *	1979-10-02	1985-05-15	Ciba Geigy Ag	Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production
FI803077A (en)	1979-10-12	1981-04-13	Ciba Geigy Ag	FOERFARANDE FOER FRAMSTAELLNING AV MYRAMYLPEPTIDER
US4409209A (en) *	1979-10-12	1983-10-11	Ciba-Geigy Corporation	Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4406889A (en) *	1980-02-15	1983-09-27	Ciba-Geigy Corporation	Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) *	1980-04-17	1983-01-11	Merck & Co., Inc.	Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4310514A (en)	1980-05-05	1982-01-12	Merck & Co., Inc.	Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (en) *	1981-01-19	1982-07-28	Ciba-Geigy Ag	Active antibiotic compositions, process for their manufacture and process for the antibiotic activity of antibiotics
GR78246B (en) *	1981-01-23	1984-09-26	Ciba Geigy Ag
JPS6042398A (en) *	1983-08-18	1985-03-06	Toshiyuki Hamaoka	Muramyldipeptide active ester derivative
EP0541486A1 (en) *	1991-11-07	1993-05-12	Ciba-Geigy Ag	Polycyclic conjugates
WO2006118327A1 (en) *	2005-04-27	2006-11-09	Oxygenix Co Ltd	Cationic amino acid type lipid
US10610564B2 (en)	2015-02-26	2020-04-07	Stc.Unm	IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
US10927147B2 (en)	2015-12-10	2021-02-23	Bharat Biotech International Limited	Muramyl peptide derivative compound, synthesis and uses thereof
US12134664B2 (en)	2015-12-10	2024-11-05	Bharat Biotech International Ltd.	Muramyl peptide derivatives
EP3389643B1 (en) *	2015-12-15	2023-05-03	Bharat Biotech International Limited	Novel muramyl peptide derivative compound, synthesis and uses thereof
EP3672939A1 (en)	2017-08-21	2020-07-01	Celgene Corporation	Processes for preparation of (s)-tert-butyl 4,5-diamino-5-oxopentanoate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4186194A (en) *	1973-10-23	1980-01-29	Agence Nationale De Valorisation De La Recherche (Anvar)	Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

1975
- 1975-12-10 CH CH1604275A patent/CH613709A5/en not_active IP Right Cessation
1976
- 1976-12-08 GB GB51228/76A patent/GB1570625A/en not_active Expired
- 1976-12-08 CA CA000267474A patent/CA1262400A/en not_active Expired
- 1976-12-08 GR GR52361A patent/GR61647B/en unknown
- 1976-12-08 NL NL7613666A patent/NL7613666A/en not_active Application Discontinuation
- 1976-12-08 DE DE19762655500 patent/DE2655500A1/en active Granted
- 1976-12-08 SU SU762428152A patent/SU660589A3/en active
- 1976-12-09 FI FI763541A patent/FI64164C/en not_active IP Right Cessation
- 1976-12-09 CS CS768063A patent/CS205027B2/en unknown
- 1976-12-09 IL IL51076A patent/IL51076A/en unknown
- 1976-12-09 FR FR7637091A patent/FR2361902A1/en active Granted
- 1976-12-09 DK DK552476A patent/DK154654C/en not_active IP Right Cessation
- 1976-12-09 NO NO764191A patent/NO144850C/en unknown
- 1976-12-09 CS CS768063A patent/CS205026B2/en unknown
- 1976-12-09 AT AT0909276A patent/AT365607B/en not_active IP Right Cessation
- 1976-12-09 CS CS768063A patent/CS205025B2/en unknown
- 1976-12-09 DD DD7600196215A patent/DD129781A5/en unknown
- 1976-12-09 IE IE2689/76A patent/IE44190B1/en not_active IP Right Cessation
- 1976-12-09 ZA ZA767333A patent/ZA767333B/en unknown
- 1976-12-09 NZ NZ182837A patent/NZ182837A/en unknown
- 1976-12-09 SE SE7613851A patent/SE445923B/en not_active IP Right Cessation
- 1976-12-09 BE BE173091A patent/BE849214A/en not_active IP Right Cessation
- 1976-12-09 PT PT65946A patent/PT65946B/en unknown
- 1976-12-09 AU AU20422/76A patent/AU508764B2/en not_active Expired
- 1976-12-09 CS CS768063A patent/CS205028B2/en unknown
- 1976-12-09 HU HU76CI1702A patent/HU177970B/en unknown
- 1976-12-10 PL PL1976194291A patent/PL110353B1/en not_active IP Right Cessation
- 1976-12-10 ES ES454118A patent/ES454118A1/en not_active Expired
- 1976-12-10 JP JP51147903A patent/JPS5273820A/en active Granted
- 1976-12-10 PL PL1976210828A patent/PL110794B1/en unknown
- 1976-12-10 PL PL1976210827A patent/PL110787B1/en unknown
- 1976-12-10 AR AR265799A patent/AR224091A1/en active
- 1976-12-10 PL PL1976210826A patent/PL112672B1/en unknown
1977
- 1977-09-08 SU SU772518658A patent/SU1060118A3/en active
- 1977-09-08 SU SU772521659A patent/SU747430A3/en active
- 1977-09-30 AR AR269405A patent/AR220686A1/en active
- 1977-12-28 ES ES465514A patent/ES465514A1/en not_active Expired
1978
- 1978-08-24 CH CH898378A patent/CH614718A5/en not_active IP Right Cessation
1983
- 1983-03-14 SG SG110/83A patent/SG11083G/en unknown
- 1983-08-25 HK HK328/83A patent/HK32883A/en unknown
1984
- 1984-12-30 MY MY123/84A patent/MY8400123A/en unknown

Also Published As

Publication number	Publication date
DK154654B (en)	1988-12-05
PL194291A1 (en)	1978-10-23
PT65946B (en)	1978-06-14
HK32883A (en)	1983-09-02
BE849214A (en)	1977-06-09
SG11083G (en)	1983-09-16
FI763541A (en)	1977-06-11
ATA909276A (en)	1981-06-15
IE44190L (en)	1977-06-10
DE2655500A1 (en)	1977-06-23
FR2361902B1 (en)	1980-11-07
JPS5273820A (en)	1977-06-21
ES465514A1 (en)	1978-09-16
CS205026B2 (en)	1981-04-30
PL112672B1 (en)	1980-10-31
CA1262400A (en)	1989-10-17
NO144850C (en)	1981-11-25
PT65946A (en)	1977-01-01
NO144850B (en)	1981-08-17
CS205028B2 (en)	1981-04-30
PL110794B1 (en)	1980-07-31
FR2361902A1 (en)	1978-03-17
SU660589A3 (en)	1979-04-30
JPS638118B2 (en)	1988-02-19
CH613709A5 (en)	1979-10-15
PL110353B1 (en)	1980-07-31
DE2655500C2 (en)	1988-12-22
IE44190B1 (en)	1981-09-09
AR224091A1 (en)	1981-10-30
AR220686A1 (en)	1980-11-28
ZA767333B (en)	1977-11-30
CH614718A5 (en)	1979-12-14
HU177970B (en)	1982-02-28
DK154654C (en)	1989-05-08
FI64164C (en)	1983-10-10
NO764191L (en)	1977-06-13
IL51076A (en)	1980-09-16
CS205027B2 (en)	1981-04-30
PL110787B1 (en)	1980-07-31
SE7613851L (en)	1977-06-11
CS205025B2 (en)	1981-04-30
AU2042276A (en)	1978-06-15
FI64164B (en)	1983-06-30
NL7613666A (en)	1977-06-14
MY8400123A (en)	1984-12-31
ES454118A1 (en)	1978-03-01
SU747430A3 (en)	1980-07-23
NZ182837A (en)	1978-07-28
GB1570625A (en)	1980-07-02
GR61647B (en)	1978-12-05
AT365607B (en)	1982-02-10
DD129781A5 (en)	1978-02-08
IL51076A0 (en)	1977-02-28
SE445923B (en)	1986-07-28
AU508764B2 (en)	1980-04-03
SU1060118A3 (en)	1983-12-07

Publication	Publication Date	Title
DK552476A (en)	1977-06-11	GLUCOSAMINE DERIVATIVES AND PROCEDURES
DK92676A (en)	1976-12-25	GRAIN-BREAKING ANTI-MATERIALS AND THEIR USE
DK495476A (en)	1977-05-07	PHENOLETHERS AND PROCEDURES FOR THEIR PREPARATION
DK270377A (en)	1978-03-09	CEPHALOSPORINE DERIVATIVES AND PROCEDURES
DK426076A (en)	1977-03-27	ANTHRAcycling glycosides
SE7606951L (en)	1976-12-19	IMIDYL-BENZENENDI AND TRICARBONIC ACID DERIVATIVES
DK557876A (en)	1977-06-13	POLYHALOGENSTEROIDS AND PROCEDURES FOR THEIR PREPARATION
DK229476A (en)	1976-11-27	PROSTAND DERIVATIVES AND PROCEDURES FOR THE MANUFACTURE OF IT
DK116576A (en)	1976-09-19	SALICYLANILIDE DERIVATIVES
DK355776A (en)	1977-02-08	4-CHROMANONES AND METHODS FOR THEIR MANUFACTURE
NO773892L (en)	1978-05-18	ANTHRACYCLE DERIVATIVES AND MANUFACTURING PROCEDURES
DK264475A (en)	1975-12-13	MACROMOLECULARS ADENINE DERIVATIVES AND PREPARATIONS
AT338440B (en)	1977-08-25	DUMMY
DK281377A (en)	1977-12-26	IODED ISOPHTHALAMIC ACID DERIVATIVES AND PROCEDURES
FR2318863A1 (en)	1977-02-18	BESTATINE AND ITS DERIVATIVES
DK355378A (en)	1979-02-13	4-HYDROXY-2-BENZIMIDAZONE DERIVATIVES AND PROCEDURES
DK427876A (en)	1977-03-24	N-SUBSTITUTED ARYLACETAMIDES AND PROCEDURES FOR THE PREPARATION
DK557776A (en)	1977-06-12	BENZYL ALCOHOL DERIVATIVES AND MANUFACTURING PROCEDURES
DK247575A (en)	1975-12-05	OXACYCLOHEXANE DERIVATIVES AND PROCEDURE
DK526976A (en)	1977-05-29	PICOLIC ACID DERIVATIVES AND MANUFACTURING PROCEDURES
DK341576A (en)	1977-01-31	HOMOPHTHALIMIDES AND PROCEDURES FOR THEIR PREPARATION
DK221476A (en)	1976-11-21	ANTIBIOTICS AND PROCEDURES FOR MANUFACTURE THEREOF
NO144253C (en)	1981-07-22	PROCEDURE AND SYSTEM FOR SEISMIC INVESTIGATIONS
DK306776A (en)	1977-01-09	2-BENZOPYRANE DERIVATIVES AND MANUFACTURING PROCEDURE
DK582775A (en)	1976-06-21	CEPHALOSPORINE DERIVATIVES AND PROCEDURES

Legal Events

Date	Code	Title	Description
1994-08-22	PBP	Patent lapsed