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DK3843759T3 - Anvendelse af tumorinfiltrerende lymfocytter til behandling af patienter med nsclc, der er refraktære over for anti-pd-1-antistof - Google Patents

Anvendelse af tumorinfiltrerende lymfocytter til behandling af patienter med nsclc, der er refraktære over for anti-pd-1-antistof Download PDF

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Publication number
DK3843759T3
DK3843759T3 DK19856433.8T DK19856433T DK3843759T3 DK 3843759 T3 DK3843759 T3 DK 3843759T3 DK 19856433 T DK19856433 T DK 19856433T DK 3843759 T3 DK3843759 T3 DK 3843759T3
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Prior art keywords
lymphocytes
antibodies
tumor
filtering
treatment
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DK19856433.8T
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English (en)
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DK3843759T5 (da
Inventor
Maria Fardis
Arvind Natarajan
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Iovance Biotherapeutics Inc
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0635—B lymphocytes
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
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    • A61K39/464499—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12N2501/20—Cytokines; Chemokines
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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DK19856433.8T 2018-08-31 2019-09-03 Anvendelse af tumorinfiltrerende lymfocytter til behandling af patienter med nsclc, der er refraktære over for anti-pd-1-antistof DK3843759T5 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862725976P 2018-08-31 2018-08-31
US201862726919P 2018-09-04 2018-09-04
PCT/US2019/049384 WO2020096682A2 (en) 2018-08-31 2019-09-03 Treatment of nsclc patients refractory for anti-pd-1 antibody

Publications (2)

Publication Number Publication Date
DK3843759T3 true DK3843759T3 (da) 2024-05-21
DK3843759T5 DK3843759T5 (da) 2024-08-19

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Application Number Title Priority Date Filing Date
DK19856433.8T DK3843759T5 (da) 2018-08-31 2019-09-03 Anvendelse af tumorinfiltrerende lymfocytter til behandling af patienter med nsclc, der er refraktære over for anti-pd-1-antistof

Country Status (19)

Country Link
US (2) US20220118012A1 (da)
EP (2) EP3843759B8 (da)
JP (1) JP2021535128A (da)
KR (1) KR20210053922A (da)
CN (1) CN112955160A (da)
AU (1) AU2019377771A1 (da)
BR (1) BR112021003491A2 (da)
CA (1) CA3111210A1 (da)
DK (1) DK3843759T5 (da)
ES (1) ES2982415T3 (da)
FI (1) FI3843759T3 (da)
HU (1) HUE066849T2 (da)
IL (1) IL281022A (da)
MX (1) MX2021002241A (da)
PL (1) PL3843759T3 (da)
PT (1) PT3843759T (da)
SG (1) SG11202101792TA (da)
TW (1) TW202031273A (da)
WO (1) WO2020096682A2 (da)

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CA3164986A1 (en) 2019-12-20 2021-06-24 Instil Bio (Uk) Limited Devices and methods for isolating tumor infiltrating lymphocytes and uses thereof
JP2024501452A (ja) * 2020-12-11 2024-01-12 アイオバンス バイオセラピューティクス，インコーポレイテッド Ｂｒａｆ阻害剤及び／またはｍｅｋ阻害剤と併用した腫瘍浸潤リンパ球治療によるがん患者の治療

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EP3843759B1 (en) 2024-02-14
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US20240307450A1 (en) 2024-09-19
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US20220118012A1 (en) 2022-04-21
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