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DK3650458T5 - Platforme til screening af kemisk kodede, rumligt adresserede biblioteker - Google Patents

Platforme til screening af kemisk kodede, rumligt adresserede biblioteker Download PDF

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Publication number
DK3650458T5
DK3650458T5 DK19196007.9T DK19196007T DK3650458T5 DK 3650458 T5 DK3650458 T5 DK 3650458T5 DK 19196007 T DK19196007 T DK 19196007T DK 3650458 T5 DK3650458 T5 DK 3650458T5
Authority
DK
Denmark
Prior art keywords
screening
platform
spatially addressed
chemically encoded
libraries
Prior art date
Application number
DK19196007.9T
Other languages
English (en)
Other versions
DK3650458T3 (da
Inventor
Jacob Berlin
Gregory COPELAND
Kathleen Elison
Hurik Muradyan
Original Assignee
Hope City
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56789474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3650458(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hope City filed Critical Hope City
Publication of DK3650458T3 publication Critical patent/DK3650458T3/da
Application granted granted Critical
Publication of DK3650458T5 publication Critical patent/DK3650458T5/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C40B50/16Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1065Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Structural Engineering (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DK19196007.9T 2015-02-24 2016-02-24 Platforme til screening af kemisk kodede, rumligt adresserede biblioteker DK3650458T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562120262P 2015-02-24 2015-02-24
EP16756316.2A EP3262059B1 (en) 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms

Publications (2)

Publication Number Publication Date
DK3650458T3 DK3650458T3 (da) 2023-09-04
DK3650458T5 true DK3650458T5 (da) 2024-08-26

Family

ID=56789474

Family Applications (3)

Application Number Title Priority Date Filing Date
DK19196007.9T DK3650458T5 (da) 2015-02-24 2016-02-24 Platforme til screening af kemisk kodede, rumligt adresserede biblioteker
DK19196019.4T DK3650459T5 (da) 2015-02-24 2016-02-24 Kemisk kodede, rumligt adresserede bibliotekscreeningsplatforme
DK16756316.2T DK3262059T3 (da) 2015-02-24 2016-02-24 Platforme til screening af kemisk kodede, rumligt adresserede biblioteker

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK19196019.4T DK3650459T5 (da) 2015-02-24 2016-02-24 Kemisk kodede, rumligt adresserede bibliotekscreeningsplatforme
DK16756316.2T DK3262059T3 (da) 2015-02-24 2016-02-24 Platforme til screening af kemisk kodede, rumligt adresserede biblioteker

Country Status (18)

Country Link
US (6) US10760181B2 (da)
EP (4) EP3650459B1 (da)
JP (2) JP6872501B2 (da)
AU (2) AU2016222755B2 (da)
CA (1) CA2976946C (da)
CY (1) CY1124954T1 (da)
DK (3) DK3650458T5 (da)
ES (3) ES2954467T3 (da)
FI (2) FI3650459T3 (da)
HR (3) HRP20230928T1 (da)
HU (3) HUE058813T2 (da)
LT (3) LT3650459T (da)
NZ (1) NZ734644A (da)
PL (3) PL3650459T3 (da)
PT (3) PT3262059T (da)
RS (3) RS62847B1 (da)
SI (3) SI3262059T1 (da)
WO (1) WO2016138184A1 (da)

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EP3650459B1 (en) 2015-02-24 2023-09-06 City of Hope Chemically encoded spatially addressed library screening platforms
EP3284851B1 (en) * 2015-04-14 2020-12-23 Hitgen Inc. Method for solid-phase synthesis of dna-encoded chemical library
US20190264199A1 (en) * 2016-11-08 2019-08-29 Nanna Therapeutics Limited Tagless encoded chemical library
US11084037B2 (en) 2017-09-25 2021-08-10 Plexium, Inc. Oligonucleotide encoded chemical libraries
WO2019089851A1 (en) 2017-10-31 2019-05-09 Encodia, Inc. Methods and kits using nucleic acid encoding and/or label
EP4041310A4 (en) 2019-10-10 2024-05-15 1859, Inc. METHODS AND SYSTEMS FOR MICROFLUIDIC SCREENING
WO2022170034A1 (en) * 2021-02-05 2022-08-11 Affinergy, Llc Rapid assay for apol1 g0 protein
TW202337974A (zh) * 2021-08-27 2023-10-01 國立大學法人神戶大學 用於於基材上產率良好地形成空孔之技術之核殼模板分子、粒子

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US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
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AU703472B2 (en) * 1993-11-02 1999-03-25 Affymax Technologies N.V. Synthesizing and screening molecular diversity
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Also Published As

Publication number Publication date
EP3650459A1 (en) 2020-05-13
HUE064689T2 (hu) 2024-04-28
PT3650458T (pt) 2023-08-31
US11015266B2 (en) 2021-05-25
FI3650458T3 (fi) 2023-08-21
EP3650458B1 (en) 2023-08-09
ES2965764T3 (es) 2024-04-16
CY1124954T1 (el) 2023-01-05
US20190390367A1 (en) 2019-12-26
US20220341059A1 (en) 2022-10-27
PL3262059T3 (pl) 2022-02-21
SI3650459T1 (sl) 2024-04-30
CA2976946A1 (en) 2016-09-01
HRP20220093T1 (hr) 2022-04-15
EP4276059A3 (en) 2024-05-01
ES2954467T3 (es) 2023-11-22
EP3262059A1 (en) 2018-01-03
HUE058813T2 (hu) 2022-09-28
DK3650458T3 (da) 2023-09-04
US20200378032A1 (en) 2020-12-03
LT3262059T (lt) 2022-02-25
NZ734644A (en) 2023-02-24
CA2976946C (en) 2023-09-19
US10760181B2 (en) 2020-09-01
JP2021106607A (ja) 2021-07-29
AU2016222755B2 (en) 2021-02-18
AU2021200399B2 (en) 2023-04-20
SI3262059T1 (sl) 2022-04-29
DK3650459T3 (da) 2023-12-11
RS64567B1 (sr) 2023-10-31
PL3650458T3 (pl) 2023-11-06
US11015265B2 (en) 2021-05-25
EP3262059B1 (en) 2022-01-05
PT3262059T (pt) 2022-01-27
SI3650458T1 (sl) 2023-11-30
LT3650459T (lt) 2023-12-27
AU2021200399A1 (en) 2021-03-18
EP3650458A1 (en) 2020-05-13
JP2018505700A (ja) 2018-03-01
US10767278B2 (en) 2020-09-08
RS62847B1 (sr) 2022-02-28
PL3650459T3 (pl) 2024-02-26
HRP20231536T1 (hr) 2024-03-15
HUE063406T2 (hu) 2024-01-28
JP6872501B2 (ja) 2021-05-19
FI3650459T3 (fi) 2023-11-28
EP3650459B1 (en) 2023-09-06
LT3650458T (lt) 2023-10-10
DK3650459T5 (da) 2024-08-26
EP4276059A2 (en) 2023-11-15
RS64899B1 (sr) 2023-12-29
AU2016222755A1 (en) 2017-08-31
EP3262059A4 (en) 2018-12-05
PT3650459T (pt) 2023-12-06
WO2016138184A1 (en) 2016-09-01
US20180245241A1 (en) 2018-08-30
ES2904997T3 (es) 2022-04-06
US20210324538A1 (en) 2021-10-21
US20200378031A1 (en) 2020-12-03
JP7109618B6 (ja) 2022-08-22
HRP20230928T1 (hr) 2023-11-24
JP7109618B2 (ja) 2022-07-29
DK3262059T3 (da) 2022-01-31

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