DK3589730T5 - Klade f adeno-associeret virus (aav) vektor og anvendelse deraf - Google Patents
Klade f adeno-associeret virus (aav) vektor og anvendelse deraf Download PDFInfo
- Publication number
- DK3589730T5 DK3589730T5 DK18711202.4T DK18711202T DK3589730T5 DK 3589730 T5 DK3589730 T5 DK 3589730T5 DK 18711202 T DK18711202 T DK 18711202T DK 3589730 T5 DK3589730 T5 DK 3589730T5
- Authority
- DK
- Denmark
- Prior art keywords
- clade
- aav
- adeno
- vector
- associated virus
- Prior art date
Links
- 241000702421 Dependoparvovirus Species 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762464748P | 2017-02-28 | 2017-02-28 | |
| US201762591002P | 2017-11-27 | 2017-11-27 | |
| US201862614002P | 2018-01-05 | 2018-01-05 | |
| PCT/US2018/019992 WO2018160582A1 (en) | 2017-02-28 | 2018-02-27 | Adeno-associated virus (aav) clade f vector and uses therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3589730T3 DK3589730T3 (da) | 2024-03-04 |
| DK3589730T5 true DK3589730T5 (da) | 2024-09-02 |
Family
ID=61628475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18711202.4T DK3589730T5 (da) | 2017-02-28 | 2018-02-27 | Klade f adeno-associeret virus (aav) vektor og anvendelse deraf |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US11827906B2 (da) |
| EP (2) | EP4272765A3 (da) |
| JP (2) | JP7455579B2 (da) |
| KR (1) | KR20190132639A (da) |
| CN (1) | CN110741082B (da) |
| AU (2) | AU2018227440B2 (da) |
| BR (1) | BR112019017839A2 (da) |
| CA (1) | CA3053399A1 (da) |
| CL (1) | CL2019002474A1 (da) |
| CO (1) | CO2019009525A2 (da) |
| DK (1) | DK3589730T5 (da) |
| ES (1) | ES2971872T3 (da) |
| FI (1) | FI3589730T3 (da) |
| HR (1) | HRP20240257T1 (da) |
| HU (1) | HUE065885T2 (da) |
| IL (1) | IL268644A (da) |
| LT (1) | LT3589730T (da) |
| MD (1) | MD3589730T2 (da) |
| MX (1) | MX2019010275A (da) |
| PE (1) | PE20191362A1 (da) |
| PL (1) | PL3589730T3 (da) |
| PT (1) | PT3589730T (da) |
| RS (1) | RS65241B1 (da) |
| SA (1) | SA519402565B1 (da) |
| SG (4) | SG10201912973XA (da) |
| SI (1) | SI3589730T1 (da) |
| WO (1) | WO2018160582A1 (da) |
| ZA (1) | ZA201905407B (da) |
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| HUE033158T2 (en) | 2003-09-30 | 2017-11-28 | Univ Pennsylvania | Adeno-associated virus (AAV) clusters, sequences, vectors containing them, and their use |
| SG10202107733QA (en) | 2015-09-28 | 2021-09-29 | Univ North Carolina Chapel Hill | Methods and compositions for antibody-evading virus vectors |
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| JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
| DK3589730T5 (da) | 2017-02-28 | 2024-09-02 | Univ Pennsylvania | Klade f adeno-associeret virus (aav) vektor og anvendelse deraf |
| AU2018265531B2 (en) | 2017-05-11 | 2024-07-11 | The Trustees Of The University Of Pennsylvania | Gene therapy for neuronal ceroid lipofuscinoses |
| MX2020005663A (es) | 2017-11-30 | 2020-08-20 | Univ Pennsylvania | Terapia genica para mucopolisacaridosis iii a. |
| JP7384797B2 (ja) | 2017-11-30 | 2023-11-21 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | ムコ多糖症ｉｉｉｂ型のための遺伝子療法 |
| BR112020017278A2 (pt) * | 2018-02-27 | 2020-12-22 | The Trustees Of The University Of Pennsylvania | Vetores de vírus adenoassociado (aav), vetores de aav tendo desamidação de capsídeos reduzida e usos para os mesmos |
| JP2021516046A (ja) * | 2018-02-27 | 2021-07-01 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 新規アデノ随伴ウイルス（ａａｖ）ベクター、低減されたカプシド脱アミド化を有するａａｖベクター、およびその使用 |
| AU2019247746B2 (en) | 2018-04-03 | 2024-08-15 | Ginkgo Bioworks, Inc. | Antibody-evading virus vectors |
| AU2019247191A1 (en) | 2018-04-03 | 2020-10-15 | Ginkgo Bioworks, Inc. | Virus vectors for targeting ophthalmic tissues |
| CA3094311A1 (en) | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Antibody-evading virus vectors |
| CN113438954A (zh) * | 2018-10-01 | 2021-09-24 | 宾夕法尼亚州大学信托人 | 可用于治疗gm1神经节苷脂病的组合物 |
| UY38407A (es) | 2018-10-15 | 2020-05-29 | Novartis Ag | Anticuerpos estabilizadores de trem2 |
| KR20210126096A (ko) | 2019-02-15 | 2021-10-19 | 상가모 테라퓨틱스, 인코포레이티드 | 재조합 aav를 제조하기 위한 조성물 및 방법 |
| TW202045730A (zh) | 2019-02-22 | 2020-12-16 | 賓州大學委員會 | 用於治療grn相關的成年發病型神經系統退化症之重組腺相關病毒 |
| AU2020229772A1 (en) | 2019-02-26 | 2021-08-26 | The Trustees Of The University Of Pennsylvania | Compositions useful in treatment of krabbe disease |
| CN113727992A (zh) | 2019-03-21 | 2021-11-30 | 斯特里迪比奥公司 | 重组腺相关病毒载体 |
| WO2020219766A1 (en) * | 2019-04-24 | 2020-10-29 | The Trustees Of The University Of Pennsylvania | Compositions useful in treatment of rett syndrome |
| PE20220930A1 (es) * | 2019-05-03 | 2022-05-31 | Univ Pennsylvania | Composiciones utiles en el tratamiento de leucodistrofia metacromatica |
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| EP4096721A1 (en) | 2020-02-02 | 2022-12-07 | The Trustees of The University of Pennsylvania | Compositions useful for treating gm1 gangliosidosis |
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