[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DK3349775T3 - Fastfase-peptidsyntesefremgangsmåder og tilhørende systemer - Google Patents

Fastfase-peptidsyntesefremgangsmåder og tilhørende systemer Download PDF

Info

Publication number
DK3349775T3
DK3349775T3 DK16847410.4T DK16847410T DK3349775T3 DK 3349775 T3 DK3349775 T3 DK 3349775T3 DK 16847410 T DK16847410 T DK 16847410T DK 3349775 T3 DK3349775 T3 DK 3349775T3
Authority
DK
Denmark
Prior art keywords
peptime
solid phase
related systems
synthesis procedures
procedures
Prior art date
Application number
DK16847410.4T
Other languages
English (en)
Inventor
Dale Arlington Thomas Iii
Alexander James Mijalis
Bradley L Pentelute
Mark David Simon
Andrea Adamo
Patrick Louis Heider
Klavs F Jensen
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Application granted granted Critical
Publication of DK3349775T3 publication Critical patent/DK3349775T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C07K1/084—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/24—Stationary reactors without moving elements inside
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/24—Stationary reactors without moving elements inside

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK16847410.4T 2015-09-17 2016-09-16 Fastfase-peptidsyntesefremgangsmåder og tilhørende systemer DK3349775T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562220232P 2015-09-17 2015-09-17
PCT/US2016/052179 WO2017049115A1 (en) 2015-09-17 2016-09-16 Solid phase peptide synthesis methods and associated systems

Publications (1)

Publication Number Publication Date
DK3349775T3 true DK3349775T3 (da) 2022-03-07

Family

ID=58276573

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16847410.4T DK3349775T3 (da) 2015-09-17 2016-09-16 Fastfase-peptidsyntesefremgangsmåder og tilhørende systemer

Country Status (7)

Country Link
US (3) US20170081359A1 (da)
EP (2) EP3960753A1 (da)
JP (1) JP7054922B2 (da)
CN (1) CN108289925A (da)
CA (1) CA2999027A1 (da)
DK (1) DK3349775T3 (da)
WO (1) WO2017049115A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9169287B2 (en) 2013-03-15 2015-10-27 Massachusetts Institute Of Technology Solid phase peptide synthesis processes and associated systems
EP3350197A4 (en) * 2015-09-17 2019-04-24 Massachusetts Institute of Technology METHODS AND SYSTEMS FOR SYNTHESIZING SOLID-STATE PEPTIDE
WO2020252266A1 (en) * 2019-06-14 2020-12-17 Mytide Therapeutics, Inc. A manufacturing process for peptide and protein production
US11049590B1 (en) 2020-02-12 2021-06-29 Peptilogics, Inc. Artificial intelligence engine architecture for generating candidate drugs
SE2050293A1 (en) * 2020-03-17 2021-09-18 Peptisystems Ab Peptide synthesis and system thereof
US11834480B2 (en) 2020-08-03 2023-12-05 Amide Technologies Protein inhibitors with reduced immunogenicity and resistance to degradation, and methods for their preparation and use
US20220165359A1 (en) 2020-11-23 2022-05-26 Peptilogics, Inc. Generating anti-infective design spaces for selecting drug candidates
US11512345B1 (en) 2021-05-07 2022-11-29 Peptilogics, Inc. Methods and apparatuses for generating peptides by synthesizing a portion of a design space to identify peptides having non-canonical amino acids
US11587643B2 (en) 2021-05-07 2023-02-21 Peptilogics, Inc. Methods and apparatuses for a unified artificial intelligence platform to synthesize diverse sets of peptides and peptidomimetics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668476A (en) * 1984-03-23 1987-05-26 Applied Biosystems, Inc. Automated polypeptide synthesis apparatus
US5807525A (en) * 1995-08-17 1998-09-15 Hybridon, Inc. Apparatus and process for multi stage solid phase synthesis of long chained organic molecules
EP0909176B1 (en) * 1997-02-11 2002-10-09 Mallinckrodt Inc. Reactor and method for solid phase peptide synthesis
WO2014042591A1 (en) * 2012-09-11 2014-03-20 Heptagon Micro Optics Pte. Ltd. Manufacture of truncated lenses, of pairs of truncated lenses and of corresponding devices
US9169287B2 (en) * 2013-03-15 2015-10-27 Massachusetts Institute Of Technology Solid phase peptide synthesis processes and associated systems

Also Published As

Publication number Publication date
EP3349775B1 (en) 2021-12-01
EP3349775A1 (en) 2018-07-25
US20230174572A1 (en) 2023-06-08
EP3960753A1 (en) 2022-03-02
CN108289925A (zh) 2018-07-17
CA2999027A1 (en) 2017-03-23
US20170081359A1 (en) 2017-03-23
US20210188901A1 (en) 2021-06-24
JP7054922B2 (ja) 2022-04-15
EP3349775A4 (en) 2019-05-15
JP2018528965A (ja) 2018-10-04
WO2017049115A1 (en) 2017-03-23

Similar Documents

Publication Publication Date Title
DK3380101T3 (da) Eif4-a-inhiberende forbindelser og fremgangsmåder relateret dertil
DK3354282T3 (da) Glycan-terapeutiske midler og relaterede fremgangsmåder deraf
DK3329001T3 (da) Genomredigeringssystemer og anvendelsesfremgangsmåder
DK3265947T3 (da) Fremgangsmåde og system til kryptering
DK3280441T3 (da) Anti-sortilin-antistoffer og fremgangsmåder til anvendelse deraf
DK3258951T3 (da) Anti-pvrig antistoffer og fremgangsmåder for anvendelse
DK3180907T3 (da) Lægemiddelinformationssystem og fremgangsmåde
DK3200615T3 (da) Kaloriefrie sødestoffer og fremgangsmåder til syntetisering
DK3183260T3 (da) Modificerede oligonukleotider og fremgangsmåder til deres syntese
DK3155024T3 (da) Opholdsstrukturer og relaterede fremgangsmåder
DK3129912T3 (da) Fremgangsmåde og system til sikring af data
DK3349775T3 (da) Fastfase-peptidsyntesefremgangsmåder og tilhørende systemer
DK3265571T3 (da) Fler-vektorsystem og anvendelse heraf
DK3116911T3 (da) Anti-mcam-antistoffer og tilhørende fremgangsmåder til anvendelse
DK3215493T3 (da) Syntese af copanlisib og dihydrochloridsalt deraf
DK3283058T3 (da) Ribociclib-tablet
DK3314589T3 (da) Alarmsystem og fremgangsmåde
DK3389669T3 (da) Triterpensaponinvarianter, syntesefremgangsmåder og anvendelse deraf
DK3231016T3 (da) Fotovoltaikmodul og fotovoltaiksystem
DK3227715T3 (da) Fremgangsmåder og systemer til positionssporing
DK3256479T3 (da) 4-substituerede benzoxaborolforbindelser og anvendelser deraf
DK3161412T3 (da) Fremgangsmåde og system til indeksering
DK3365321T3 (da) Solabegron-zwitterion og anvendelser deraf
DK3280405T3 (da) Inhibitorer og anvendelser deraf
DK3245219T3 (da) Glypicanepitoper og anvendelser deraf