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DK3087183T3 - Modulation af angiopoietin-3-lignende ekspression - Google Patents

Modulation af angiopoietin-3-lignende ekspression Download PDF

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Publication number
DK3087183T3
DK3087183T3 DK14874081.4T DK14874081T DK3087183T3 DK 3087183 T3 DK3087183 T3 DK 3087183T3 DK 14874081 T DK14874081 T DK 14874081T DK 3087183 T3 DK3087183 T3 DK 3087183T3
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Prior art keywords
angiopoietin
modulation
expression
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DK14874081.4T
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English (en)
Inventor
Susan M Freier
Mark J Graham
Rosanne M Crooke
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Ionis Pharmaceuticals Inc
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Publication of DK3087183T3 publication Critical patent/DK3087183T3/da

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
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    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • A—HUMAN NECESSITIES
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    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
    • A—HUMAN NECESSITIES
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DK14874081.4T 2013-12-24 2014-12-24 Modulation af angiopoietin-3-lignende ekspression DK3087183T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361920652P 2013-12-24 2013-12-24
PCT/US2014/072303 WO2015100394A1 (en) 2013-12-24 2014-12-24 Modulation of angiopoietin-like 3 expression

Publications (1)

Publication Number Publication Date
DK3087183T3 true DK3087183T3 (da) 2020-09-14

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DK14874081.4T DK3087183T3 (da) 2013-12-24 2014-12-24 Modulation af angiopoietin-3-lignende ekspression

Country Status (19)

Country Link
US (3) US20170037409A1 (da)
EP (2) EP3770259A1 (da)
JP (2) JP6643996B2 (da)
KR (2) KR102298476B1 (da)
CN (3) CN105814204B (da)
AU (2) AU2014369900B2 (da)
BR (1) BR112016013473A2 (da)
CA (1) CA2931510A1 (da)
DK (1) DK3087183T3 (da)
ES (1) ES2830257T3 (da)
HU (1) HUE052243T2 (da)
IL (2) IL245707B (da)
MX (1) MX2016008462A (da)
NZ (1) NZ720286A (da)
PL (1) PL3087183T3 (da)
PT (1) PT3087183T (da)
RU (1) RU2706964C2 (da)
SI (1) SI3087183T1 (da)
WO (1) WO2015100394A1 (da)

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CN118291456A (zh) 2017-12-01 2024-07-05 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
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WO2019105435A1 (zh) 2017-12-01 2019-06-06 苏州瑞博生物技术有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
EP3719126A4 (en) * 2017-12-01 2021-10-20 Suzhou Ribo Life Science Co., Ltd. NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING NUCLEIC ACID, ASSOCIATED PREPARATION PROCESS AND USE
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WO2020099525A2 (en) * 2018-11-13 2020-05-22 Lipigon Pharmaceuticals Ab Oligonucleotides influencing the regulation of the fatty acid metabolism
CN111973617A (zh) * 2019-05-23 2020-11-24 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
WO2021207710A2 (en) * 2020-04-09 2021-10-14 Verve Therapeutics, Inc. Base editing of angptl3 and methods of using same for treatment of disease
EP4229200A1 (en) * 2020-10-16 2023-08-23 Sanofi Novel rna compositions and methods for inhibiting angptl3
CN113956345B (zh) * 2021-09-10 2024-04-23 北京大学 Angpt4蛋白及其编码基因在调控心脏损伤后的修复与再生能力中的应用
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WO2023134705A1 (zh) * 2022-01-11 2023-07-20 上海金中锘美生物医药科技有限公司 抑制angptl3表达的rna干扰剂及其用途
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US20220403393A1 (en) 2022-12-22
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