DK248078A - Phatalaziner og fremgangsmaade til fremstilling deraf - Google Patents

Phatalaziner og fremgangsmaade til fremstilling deraf

Info

Publication number: DK248078A
Authority: DK; Denmark
Prior art keywords: phatalazines; manufacture; methods
Prior art date: 1977-06-03

Application number

DK248078A

Other languages

English (en)

Inventor

S F Campbell

J C Danilewicz

A G Evans

A L Ham

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-06-03

Filing date

1978-06-02

Publication date

1978-12-04

1978-06-02 Application filed by Pfizer filed Critical Pfizer

1978-12-04 Publication of DK248078A publication Critical patent/DK248078A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK248078A 1977-06-03 1978-06-02 Phatalaziner og fremgangsmaade til fremstilling deraf DK248078A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2358277		1977-06-03

Publications (1)

Publication Number	Publication Date
DK248078A true DK248078A (da)	1978-12-04

Family

ID=10198020

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK248078A DK248078A (da)	1977-06-03	1978-06-02	Phatalaziner og fremgangsmaade til fremstilling deraf

Country Status (29)

Country	Link
US (1)	US4289772A (da)
JP (1)	JPS5416488A (da)
AR (2)	AR222013A1 (da)
AT (2)	AT362792B (da)
AU (1)	AU505373B1 (da)
BE (1)	BE867727A (da)
CA (1)	CA1111850A (da)
DD (1)	DD137355A5 (da)
DE (1)	DE2824064A1 (da)
DK (1)	DK248078A (da)
EG (1)	EG13527A (da)
ES (4)	ES470470A1 (da)
FI (1)	FI781753A (da)
FR (1)	FR2392986A1 (da)
GB (1)	GB2000136B (da)
GR (1)	GR74402B (da)
HU (1)	HU179745B (da)
IL (1)	IL54842A (da)
IN (3)	IN148482B (da)
IT (1)	IT1094944B (da)
LU (1)	LU79761A1 (da)
NL (1)	NL7806016A (da)
NO (1)	NO781935L (da)
NZ (1)	NZ187453A (da)
PL (3)	PL116420B1 (da)
PT (1)	PT68126A (da)
SE (1)	SE7806519L (da)
SU (2)	SU856383A3 (da)
ZA (1)	ZA783183B (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4370328A (en) *	1977-11-03	1983-01-25	Pfizer Inc.	Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
IL59619A0 (en) *	1979-03-28	1980-06-30	Pfizer	Phthalazine derivatives,their preparation and pharmaceutical compositions containing them
PL135545B1 (en) *	1980-03-01	1985-11-30	Wyeth John & Brother Ltd	Process for preparing novel derivatives of piperidine
GB8320958D0 (en) *	1983-08-03	1983-09-07	Pfizer Ltd	Quinazoline cardiac stimulants
US5001125A (en) *	1984-03-26	1991-03-19	Janssen Pharmaceutica N.V.	Anti-virally active pyridazinamines
US4882354A (en) *	1987-12-16	1989-11-21	Norwich Eaton Pharmaceuticals, Inc.	N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
US5300515A (en) *	1991-01-31	1994-04-05	Kyorin Pharmaceutical Co., Ltd.	Carbamic acid derivatives and method for preparing the same
JP3169188B2 (ja) *	1991-01-31	2001-05-21	杏林製薬株式会社	カルバミン酸誘導体及びその製造方法
EP0621267A1 (en) *	1993-04-07	1994-10-26	Shell Internationale Researchmaatschappij B.V.	Spiropiperidine derivatives and their use as fungicides
US5728712A (en) *	1995-05-19	1998-03-17	Chiroscience Limited	3,4-disubstituted-phenylsulphonamides and their therapeutic use
WO1998007430A1 (fr) *	1996-08-20	1998-02-26	Eisai Co., Ltd.	Medicament contre les defaillances de l'erection, renfermant un compose a base de pyridazine fondue
US20030186963A1 (en)	2001-09-14	2003-10-02	Dorwald Florencio Zaragoza	Substituted piperidines
DE60335118D1 (de) *	2002-08-16	2011-01-05	Janssen Pharmaceutica Nv	Piperidinylverbindungen, die selektiv an integrine binden
US20040224986A1 (en) *	2002-08-16	2004-11-11	Bart De Corte	Piperidinyl targeting compounds that selectively bind integrins
US20060019975A1 (en) *	2004-07-23	2006-01-26	Pfizer Inc	Novel piperidyl derivatives of quinazoline and isoquinoline
TW200630337A (en)	2004-10-14	2006-09-01	Euro Celtique Sa	Piperidinyl compounds and the use thereof
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
US7678363B2 (en)	2005-08-26	2010-03-16	Braincells Inc	Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP1940389A2 (en)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
US20070112017A1 (en)	2005-10-31	2007-05-17	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
EP1981868A2 (en) *	2006-01-27	2008-10-22	Pfizer Products Inc.	Aminophthalazine derivative compounds
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
WO2007110449A1 (en)	2006-03-29	2007-10-04	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use
WO2007118854A1 (en)	2006-04-13	2007-10-25	Euro-Celtique S.A.	Benzenesulfonamide compounds and the use thereof
WO2007118853A1 (en)	2006-04-13	2007-10-25	Euro-Celtique S.A.	Benzenesulfonamide compounds and their use as blockers of calcium channels
AU2007249435A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 HT receptor mediated neurogenesis
WO2007134136A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
EP1900731A1 (de) *	2006-09-07	2008-03-19	Bayer Schering Pharma Aktiengesellschaft	N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren
EP1903037A1 (de) *	2006-09-07	2008-03-26	Bayer Schering Pharma Aktiengesellschaft	1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
EP2068872A1 (en)	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
US8399486B2 (en)	2007-04-09	2013-03-19	Purdue Pharma L.P.	Benzenesulfonyl compounds and the use thereof
CN101778837A (zh)	2007-08-07	2010-07-14	弗·哈夫曼-拉罗切有限公司	作为nk3受体拮抗剂的吡咯烷芳基-醚
CA2697325A1 (en)	2007-08-22	2009-02-26	F. Hoffmann-La Roche Ag	Pyrrolidine aryl-ether as nk3 receptor antagonists
KR101174980B1 (ko) *	2007-09-14	2012-08-17	에프. 호프만-라 로슈 아게	Ｎｋ３ 수용체 길항제로서의 피페리딘 유도체
US8765736B2 (en)	2007-09-28	2014-07-01	Purdue Pharma L.P.	Benzenesulfonamide compounds and the use thereof
US20100216805A1 (en)	2009-02-25	2010-08-26	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
AR077014A1 (es)	2009-06-19	2011-07-27	Lilly Co Eli	Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
WO2013106547A1 (en)	2012-01-10	2013-07-18	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
CN113087654B (zh) *	2021-04-15	2022-12-23	苏州昊帆生物股份有限公司	哌啶-4-丁胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1094044A (en) *	1965-07-12	1967-12-06	Vantorex Ltd	Phthalazine derivatives
GB1199768A (en)	1966-10-31	1970-07-22	Pfizer & Co C	Nitrogen Heterocycles and process for their preparation
GB1293565A (en) *	1969-05-03	1972-10-18	Aspro Nicholas Ltd	Aminophthalazines and pharmaceutical compositions thereof
GB1460389A (en)	1974-07-25	1977-01-06	Pfizer Ltd	4-substituted quinazoline cardiac stimulants

1978
- 1978-05-15 IN IN364/DEL/78A patent/IN148482B/en unknown
- 1978-06-01 IT IT24106/78A patent/IT1094944B/it active
- 1978-06-01 NZ NZ187453A patent/NZ187453A/xx unknown
- 1978-06-01 PT PT68126A patent/PT68126A/pt unknown
- 1978-06-01 DE DE19782824064 patent/DE2824064A1/de not_active Ceased
- 1978-06-01 BE BE188257A patent/BE867727A/xx unknown
- 1978-06-01 IL IL54842A patent/IL54842A/xx unknown
- 1978-06-01 JP JP6627978A patent/JPS5416488A/ja active Granted
- 1978-06-01 GR GR56414A patent/GR74402B/el unknown
- 1978-06-01 GB GB7826202A patent/GB2000136B/en not_active Expired
- 1978-06-01 FI FI781753A patent/FI781753A/fi not_active Application Discontinuation
- 1978-06-02 SU SU782624349A patent/SU856383A3/ru active
- 1978-06-02 PL PL1978217896A patent/PL116420B1/pl unknown
- 1978-06-02 HU HU78PI629A patent/HU179745B/hu unknown
- 1978-06-02 CA CA304,700A patent/CA1111850A/en not_active Expired
- 1978-06-02 NL NL7806016A patent/NL7806016A/xx not_active Application Discontinuation
- 1978-06-02 DK DK248078A patent/DK248078A/da not_active Application Discontinuation
- 1978-06-02 AU AU36839/78A patent/AU505373B1/en not_active Expired
- 1978-06-02 SE SE7806519A patent/SE7806519L/xx unknown
- 1978-06-02 NO NO781935A patent/NO781935L/no unknown
- 1978-06-02 AT AT0400878A patent/AT362792B/de not_active IP Right Cessation
- 1978-06-02 ES ES470470A patent/ES470470A1/es not_active Expired
- 1978-06-02 AR AR272434A patent/AR222013A1/es active
- 1978-06-02 ZA ZA00783183A patent/ZA783183B/xx unknown
- 1978-06-02 FR FR7816545A patent/FR2392986A1/fr active Granted
- 1978-06-02 PL PL1978207337A patent/PL113208B1/pl unknown
- 1978-06-02 PL PL1978217897A patent/PL116437B1/pl unknown
- 1978-06-02 DD DD78205751A patent/DD137355A5/xx unknown
- 1978-06-02 LU LU79761A patent/LU79761A1/fr unknown
- 1978-06-03 EG EG354/78A patent/EG13527A/xx active
1979
- 1979-03-01 ES ES478199A patent/ES478199A1/es not_active Expired
- 1979-03-01 ES ES478201A patent/ES478201A1/es not_active Expired
- 1979-03-01 ES ES478200A patent/ES478200A1/es not_active Expired
- 1979-06-18 SU SU792777649A patent/SU862826A3/ru active
- 1979-12-13 US US06/103,342 patent/US4289772A/en not_active Expired - Lifetime
1980
- 1980-02-12 AR AR279935A patent/AR223999A1/es active
- 1980-05-20 IN IN368/DEL/80A patent/IN149550B/en unknown
- 1980-06-10 AT AT0305080A patent/AT363096B/de not_active IP Right Cessation
1981
- 1981-01-13 IN IN19/DEL/81A patent/IN149973B/en unknown

Also Published As

Publication number	Publication date
IN149973B (da)	1982-06-19
PL113208B1 (en)	1980-11-29
IN148482B (da)	1981-03-07
ES478200A1 (es)	1980-01-01
AT362792B (de)	1981-06-10
JPS5416488A (en)	1979-02-07
ES478199A1 (es)	1980-01-16
ES478201A1 (es)	1980-02-01
NL7806016A (nl)	1978-12-05
AU505373B1 (en)	1979-11-15
DE2824064A1 (de)	1978-12-14
NZ187453A (en)	1980-12-19
SU862826A3 (ru)	1981-09-07
LU79761A1 (fr)	1980-01-22
NO781935L (no)	1978-12-05
AR223999A1 (es)	1981-10-15
AR222013A1 (es)	1981-04-15
PL207337A1 (pl)	1979-06-04
IT1094944B (it)	1985-08-10
GB2000136B (en)	1982-01-06
ES470470A1 (es)	1979-09-01
EG13527A (en)	1981-12-31
HU179745B (en)	1982-12-28
AT363096B (de)	1981-07-10
US4289772A (en)	1981-09-15
SU856383A3 (ru)	1981-08-15
IL54842A (en)	1982-01-31
GR74402B (da)	1984-06-28
FI781753A (fi)	1978-12-04
PL116420B1 (en)	1981-06-30
JPS5538351B2 (da)	1980-10-03
IN149550B (da)	1982-01-16
FR2392986A1 (fr)	1978-12-29
PL116437B1 (en)	1981-06-30
PT68126A (en)	1978-07-01
ZA783183B (en)	1979-06-27
DD137355A5 (de)	1979-08-29
SE7806519L (sv)	1978-12-04
GB2000136A (en)	1979-01-04
ATA305080A (de)	1980-12-15
IL54842A0 (en)	1978-08-31
ATA400878A (de)	1980-11-15
CA1111850A (en)	1981-11-03
FR2392986B1 (da)	1982-07-16
IT7824106A0 (it)	1978-06-01
BE867727A (fr)	1978-12-01

Publication	Publication Date	Title
DK248078A (da)	1978-12-04	Phatalaziner og fremgangsmaade til fremstilling deraf
DK454178A (da)	1979-04-13	Acylanilider og fremgangsmaade til fremstilling deraf
DK137378A (da)	1978-10-01	Taeppe og fremgangsmaade til fremstilling deraf
DK102177A (da)	1977-09-10	Aminoalkyl-heterocycliske forbindelser og fremgangsmade til fremstilling deraf
DK389478A (da)	1979-03-08	Termoplastiske aromatiske polyetherketoner og fremgangsmaade til fremstilling deraf
DK556978A (da)	1979-06-16	Acylanilid og fremgangsmaade til fremstilling deraf
DK372878A (da)	1979-02-26	Thiadiazolylcephalosporinanaloge og fremgangsmaade til fremstilling deraf
DK319277A (da)	1978-01-15	Hydroxysuccinimidestere fremgangsmade til fremstilling heraf og anvendelse heraf
DK474078A (da)	1979-04-27	Endeloest forbindelsesbaand og fremgangsmaade til fremstilling deraf
DK502977A (da)	1978-05-17	Antracyklinderivat og fremgangsmaade til fremstilling deraf
DK335876A (da)	1977-01-25	3-oximer af d-17alfa-ethynyl-19-nortestosteronestere og fremgangsmade til fremstilling deraf
DK308578A (da)	1979-02-02	Meningokokvaccine og fremgangsmaade til fremstilling heraf
DK495578A (da)	1979-05-09	Quinazolderivater og fremgangsmaade til fremstilling deraf
DK581378A (da)	1979-06-24	Keramisk form og fremgangsmaade til fremstilling deraf
DK96177A (da)	1977-09-06	4-androsten-3-oner og fremgangsmade til fremstilling heraf
DK266578A (da)	1978-12-22	Herbicide cyklopropylmethoxyanilider og fremgangsmaade til fremstilling deraf
DK12478A (da)	1978-07-13	Dithienylalkylaminer og fremgangsmaade til fremstilling deraf
DK413578A (da)	1979-03-22	Isoquinolinderivater og fremgangsmaade til fremstilling deraf
DK554078A (da)	1979-06-09	Tetrapeptider og fremgangsmaade til fremstilling deraf
DK224279A (da)	1979-12-01	Polyjodbenzenderivater og fremgangsmaade til fremstilling deraf
DK151570C (da)	1988-06-06	Afsvovlningsmiddel og fremgangsmaade til fremstilling deraf
DK270279A (da)	1979-12-28	Cystaminderivater og fremgangsmaade til fremstilling deraf
DK213878A (da)	1978-11-17	17beta-hydroxy-4-androsten-3-on og fremgangsmaade til fremstilling heraf
DK54678A (da)	1978-08-09	Azetidinonderivater og fremgangsmaade til fremstilling deraf
DK111578A (da)	1978-09-15	Steroid/spirooxazolidiner og fremgangsmaade til fremstilling deraf

Legal Events

Date	Code	Title	Description
1984-03-17	AHS	Application shelved for other reasons than non-payment