DK224184D0 - Parenteralt praeparat af nimodipin,fremgangsmaade til dets fremstilling samt dets anvendelse ved bekaempelse af sygdomme - Google Patents
Parenteralt praeparat af nimodipin,fremgangsmaade til dets fremstilling samt dets anvendelse ved bekaempelse af sygdommeInfo
- Publication number
- DK224184D0 DK224184D0 DK2241/84A DK224184A DK224184D0 DK 224184 D0 DK224184 D0 DK 224184D0 DK 2241/84 A DK2241/84 A DK 2241/84A DK 224184 A DK224184 A DK 224184A DK 224184 D0 DK224184 D0 DK 224184D0
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- weight
- nimodipin
- procedure
- application
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833316510 DE3316510A1 (de) | 1983-05-06 | 1983-05-06 | Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen |
DE3316510 | 1983-05-06 |
Publications (4)
Publication Number | Publication Date |
---|---|
DK224184D0 true DK224184D0 (da) | 1984-05-04 |
DK224184A DK224184A (da) | 1984-11-07 |
DK164148B DK164148B (da) | 1992-05-18 |
DK164148C DK164148C (da) | 1992-10-26 |
Family
ID=6198265
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK224184A DK164148C (da) | 1983-05-06 | 1984-05-04 | Parenteralt praeparat af nimodipin og fremgangsmaade til dets fremstilling |
Country Status (19)
Country | Link |
---|---|
US (1) | US5114956A (da) |
EP (1) | EP0126315B1 (da) |
JP (1) | JPS59206305A (da) |
KR (1) | KR920000306B1 (da) |
AT (1) | ATE24835T1 (da) |
AU (1) | AU562293B2 (da) |
BE (1) | BE899564A (da) |
CA (1) | CA1220424A (da) |
DE (2) | DE3316510A1 (da) |
DK (1) | DK164148C (da) |
ES (1) | ES8505542A1 (da) |
FR (1) | FR2545354B1 (da) |
GR (1) | GR81609B (da) |
HK (1) | HK75889A (da) |
IL (1) | IL71744A (da) |
IT (1) | IT1181804B (da) |
PT (1) | PT78542B (da) |
SG (1) | SG44489G (da) |
ZA (1) | ZA843352B (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60246313A (ja) * | 1984-05-22 | 1985-12-06 | Yamanouchi Pharmaceut Co Ltd | 塩酸ニカルジピンの注射剤およびその製法 |
FR2585574B1 (fr) * | 1985-07-31 | 1988-09-09 | Corbiere Jerome | Nouvelles compositions pharmaceutiques anti-glaucomateuses a base de 1,4-dihydropyridines et leur procede d'obtention |
AT387518B (de) * | 1985-12-18 | 1989-02-10 | Bayer Ag | Verfahren zur herstellung von fluessigen spruehpraeparaten von dihydropyridinen |
DE3544692A1 (de) * | 1985-12-18 | 1987-06-19 | Bayer Ag | Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung |
DE3702105A1 (de) * | 1987-01-24 | 1988-08-04 | Bayer Ag | Parenterale loesung |
CA2011063C (en) * | 1989-02-28 | 1999-07-06 | Calum B. Macfarlane | Nicardipine pharmaceutical composition for parenteral administration |
RU1804845C (ru) * | 1991-02-15 | 1993-03-30 | Институт Органического Синтеза Латвийской Ан | Ноотропное вещество |
ATE532530T1 (de) * | 1994-12-12 | 2011-11-15 | Omeros Corp | Bespüllungslösung und deren verwendung zur perioperativen hemmung von schmerzen, entzündungen und/oder spasmen an einer gefässstruktur |
US6492332B1 (en) | 1995-12-12 | 2002-12-10 | Omeros Corporation | Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation |
KR100517210B1 (ko) * | 1994-12-12 | 2006-06-07 | 오메로스 코포레이션 | 통증,염증및경련억제용관주용액 |
JPH10510540A (ja) | 1994-12-12 | 1998-10-13 | オメロス メディカル システムズ,インコーポレーテッド | 灌注用溶液並びに疼痛、炎症及びけいれんの抑制法 |
US6413961B1 (en) | 1995-12-12 | 2002-07-02 | Omeros Medical Systems, Inc. | Irrigation solution and method for inhibition of pain and inflammation |
US6136799A (en) * | 1998-04-08 | 2000-10-24 | Abbott Laboratories | Cosolvent formulations |
DE10142417A1 (de) * | 2001-08-31 | 2003-03-20 | Molecular And Clinical Drug Re | Arzneimittel |
DE10142416A1 (de) * | 2001-08-31 | 2003-03-20 | Molecular And Clinical Drug Re | Verfahren zur Herstellung von Lösungen |
US8034762B2 (en) * | 2004-09-02 | 2011-10-11 | Cognosci, Inc. | Treatment of subarachnoid hemorrhage with Apo E analogs |
CA2625862A1 (en) * | 2005-10-14 | 2007-04-26 | Transform Pharmaceuticals, Inc. | Liquid pharmaceutical compositions of nimodipine |
WO2007125028A1 (de) * | 2006-04-28 | 2007-11-08 | Basf Se | Verfahren zur solubilisierung von hydrophoben wirkstoffen in wässrigem medium |
US8728504B2 (en) | 2010-02-05 | 2014-05-20 | Basf Se | Process for solubilizing hydrophobic active ingredients in aqueous medium |
EP2531548A1 (de) | 2010-02-05 | 2012-12-12 | Basf Se | Verfahren zur solubilisierung von hydrophoben wirkstoffen in wässrigem medium |
WO2012148799A1 (en) | 2011-04-28 | 2012-11-01 | Board Of Regents, The University Of Texas System | Improved parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same |
US10092553B2 (en) | 2016-04-13 | 2018-10-09 | Nortic Holdings Inc. | Stable nimodipine parenteral formulation |
SI3442586T1 (sl) | 2016-04-13 | 2023-01-31 | Acasti Pharma U.S., Inc. | Stabilna parenteralna formulacija nimopidina |
WO2019165066A2 (en) | 2018-02-22 | 2019-08-29 | Nortic Holdings Inc. | Stable nimodipine parenteral formulation |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
US4154839A (en) * | 1975-11-05 | 1979-05-15 | Bayer Aktiengesellschaft | 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine |
DE2650013C3 (de) * | 1976-10-30 | 1981-04-02 | Bayer Ag, 5090 Leverkusen | 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel |
DE2815578C2 (de) * | 1978-04-11 | 1986-01-16 | Bayer Ag, 5090 Leverkusen | Neue pharmazeutische Verwendung von Nimodipin |
DE2841667A1 (de) * | 1978-09-25 | 1980-04-10 | Bayer Ag | Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1983
- 1983-05-06 DE DE19833316510 patent/DE3316510A1/de not_active Withdrawn
-
1984
- 1984-04-24 EP EP84104563A patent/EP0126315B1/de not_active Expired
- 1984-04-24 AT AT84104563T patent/ATE24835T1/de not_active IP Right Cessation
- 1984-04-24 DE DE8484104563T patent/DE3461988D1/de not_active Expired
- 1984-04-27 ES ES531995A patent/ES8505542A1/es not_active Expired
- 1984-05-01 JP JP59086280A patent/JPS59206305A/ja active Granted
- 1984-05-02 AU AU27583/84A patent/AU562293B2/en not_active Expired
- 1984-05-03 IL IL71744A patent/IL71744A/xx not_active IP Right Cessation
- 1984-05-03 KR KR1019840002390A patent/KR920000306B1/ko not_active IP Right Cessation
- 1984-05-03 BE BE0/212864A patent/BE899564A/fr not_active IP Right Cessation
- 1984-05-04 IT IT48139/84A patent/IT1181804B/it active
- 1984-05-04 FR FR8406974A patent/FR2545354B1/fr not_active Expired
- 1984-05-04 PT PT78542A patent/PT78542B/pt unknown
- 1984-05-04 DK DK224184A patent/DK164148C/da not_active IP Right Cessation
- 1984-05-04 GR GR74600A patent/GR81609B/el unknown
- 1984-05-04 ZA ZA843352A patent/ZA843352B/xx unknown
- 1984-05-04 CA CA000453627A patent/CA1220424A/en not_active Expired
-
1989
- 1989-07-25 SG SG44489A patent/SG44489G/en unknown
- 1989-09-21 HK HK758/89A patent/HK75889A/xx not_active IP Right Cessation
-
1991
- 1991-01-15 US US07/641,323 patent/US5114956A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
SG44489G (en) | 1989-11-17 |
ZA843352B (en) | 1984-12-24 |
US5114956A (en) | 1992-05-19 |
GR81609B (da) | 1984-12-11 |
EP0126315B1 (de) | 1987-01-14 |
KR840009031A (ko) | 1984-12-24 |
ES531995A0 (es) | 1985-06-01 |
AU2758384A (en) | 1984-11-08 |
FR2545354A1 (fr) | 1984-11-09 |
DE3316510A1 (de) | 1984-11-08 |
CA1220424A (en) | 1987-04-14 |
ES8505542A1 (es) | 1985-06-01 |
ATE24835T1 (de) | 1987-01-15 |
IT1181804B (it) | 1987-09-30 |
FR2545354B1 (fr) | 1986-09-26 |
DK164148B (da) | 1992-05-18 |
EP0126315A1 (de) | 1984-11-28 |
IL71744A0 (en) | 1984-09-30 |
KR920000306B1 (ko) | 1992-01-11 |
JPH0422888B2 (da) | 1992-04-20 |
IT8448139A0 (it) | 1984-05-04 |
PT78542B (en) | 1986-07-14 |
IL71744A (en) | 1988-04-29 |
DE3461988D1 (en) | 1987-02-19 |
DK224184A (da) | 1984-11-07 |
JPS59206305A (ja) | 1984-11-22 |
DK164148C (da) | 1992-10-26 |
HK75889A (en) | 1989-09-29 |
PT78542A (en) | 1984-06-01 |
AU562293B2 (en) | 1987-06-04 |
BE899564A (fr) | 1984-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |