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DK224184D0 - Parenteralt praeparat af nimodipin,fremgangsmaade til dets fremstilling samt dets anvendelse ved bekaempelse af sygdomme - Google Patents

Parenteralt praeparat af nimodipin,fremgangsmaade til dets fremstilling samt dets anvendelse ved bekaempelse af sygdomme

Info

Publication number
DK224184D0
DK224184D0 DK2241/84A DK224184A DK224184D0 DK 224184 D0 DK224184 D0 DK 224184D0 DK 2241/84 A DK2241/84 A DK 2241/84A DK 224184 A DK224184 A DK 224184A DK 224184 D0 DK224184 D0 DK 224184D0
Authority
DK
Denmark
Prior art keywords
preparation
weight
nimodipin
procedure
application
Prior art date
Application number
DK2241/84A
Other languages
English (en)
Other versions
DK164148B (da
DK224184A (da
DK164148C (da
Inventor
Dieter Hoff
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK224184D0 publication Critical patent/DK224184D0/da
Publication of DK224184A publication Critical patent/DK224184A/da
Publication of DK164148B publication Critical patent/DK164148B/da
Application granted granted Critical
Publication of DK164148C publication Critical patent/DK164148C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
DK224184A 1983-05-06 1984-05-04 Parenteralt praeparat af nimodipin og fremgangsmaade til dets fremstilling DK164148C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833316510 DE3316510A1 (de) 1983-05-06 1983-05-06 Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
DE3316510 1983-05-06

Publications (4)

Publication Number Publication Date
DK224184D0 true DK224184D0 (da) 1984-05-04
DK224184A DK224184A (da) 1984-11-07
DK164148B DK164148B (da) 1992-05-18
DK164148C DK164148C (da) 1992-10-26

Family

ID=6198265

Family Applications (1)

Application Number Title Priority Date Filing Date
DK224184A DK164148C (da) 1983-05-06 1984-05-04 Parenteralt praeparat af nimodipin og fremgangsmaade til dets fremstilling

Country Status (19)

Country Link
US (1) US5114956A (da)
EP (1) EP0126315B1 (da)
JP (1) JPS59206305A (da)
KR (1) KR920000306B1 (da)
AT (1) ATE24835T1 (da)
AU (1) AU562293B2 (da)
BE (1) BE899564A (da)
CA (1) CA1220424A (da)
DE (2) DE3316510A1 (da)
DK (1) DK164148C (da)
ES (1) ES8505542A1 (da)
FR (1) FR2545354B1 (da)
GR (1) GR81609B (da)
HK (1) HK75889A (da)
IL (1) IL71744A (da)
IT (1) IT1181804B (da)
PT (1) PT78542B (da)
SG (1) SG44489G (da)
ZA (1) ZA843352B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60246313A (ja) * 1984-05-22 1985-12-06 Yamanouchi Pharmaceut Co Ltd 塩酸ニカルジピンの注射剤およびその製法
FR2585574B1 (fr) * 1985-07-31 1988-09-09 Corbiere Jerome Nouvelles compositions pharmaceutiques anti-glaucomateuses a base de 1,4-dihydropyridines et leur procede d'obtention
AT387518B (de) * 1985-12-18 1989-02-10 Bayer Ag Verfahren zur herstellung von fluessigen spruehpraeparaten von dihydropyridinen
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
DE3702105A1 (de) * 1987-01-24 1988-08-04 Bayer Ag Parenterale loesung
CA2011063C (en) * 1989-02-28 1999-07-06 Calum B. Macfarlane Nicardipine pharmaceutical composition for parenteral administration
RU1804845C (ru) * 1991-02-15 1993-03-30 Институт Органического Синтеза Латвийской Ан Ноотропное вещество
ATE532530T1 (de) * 1994-12-12 2011-11-15 Omeros Corp Bespüllungslösung und deren verwendung zur perioperativen hemmung von schmerzen, entzündungen und/oder spasmen an einer gefässstruktur
US6492332B1 (en) 1995-12-12 2002-12-10 Omeros Corporation Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
KR100517210B1 (ko) * 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
JPH10510540A (ja) 1994-12-12 1998-10-13 オメロス メディカル システムズ,インコーポレーテッド 灌注用溶液並びに疼痛、炎症及びけいれんの抑制法
US6413961B1 (en) 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
US6136799A (en) * 1998-04-08 2000-10-24 Abbott Laboratories Cosolvent formulations
DE10142417A1 (de) * 2001-08-31 2003-03-20 Molecular And Clinical Drug Re Arzneimittel
DE10142416A1 (de) * 2001-08-31 2003-03-20 Molecular And Clinical Drug Re Verfahren zur Herstellung von Lösungen
US8034762B2 (en) * 2004-09-02 2011-10-11 Cognosci, Inc. Treatment of subarachnoid hemorrhage with Apo E analogs
CA2625862A1 (en) * 2005-10-14 2007-04-26 Transform Pharmaceuticals, Inc. Liquid pharmaceutical compositions of nimodipine
WO2007125028A1 (de) * 2006-04-28 2007-11-08 Basf Se Verfahren zur solubilisierung von hydrophoben wirkstoffen in wässrigem medium
US8728504B2 (en) 2010-02-05 2014-05-20 Basf Se Process for solubilizing hydrophobic active ingredients in aqueous medium
EP2531548A1 (de) 2010-02-05 2012-12-12 Basf Se Verfahren zur solubilisierung von hydrophoben wirkstoffen in wässrigem medium
WO2012148799A1 (en) 2011-04-28 2012-11-01 Board Of Regents, The University Of Texas System Improved parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
US10092553B2 (en) 2016-04-13 2018-10-09 Nortic Holdings Inc. Stable nimodipine parenteral formulation
SI3442586T1 (sl) 2016-04-13 2023-01-31 Acasti Pharma U.S., Inc. Stabilna parenteralna formulacija nimopidina
WO2019165066A2 (en) 2018-02-22 2019-08-29 Nortic Holdings Inc. Stable nimodipine parenteral formulation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
US4154839A (en) * 1975-11-05 1979-05-15 Bayer Aktiengesellschaft 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
DE2650013C3 (de) * 1976-10-30 1981-04-02 Bayer Ag, 5090 Leverkusen 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
DE2841667A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
SG44489G (en) 1989-11-17
ZA843352B (en) 1984-12-24
US5114956A (en) 1992-05-19
GR81609B (da) 1984-12-11
EP0126315B1 (de) 1987-01-14
KR840009031A (ko) 1984-12-24
ES531995A0 (es) 1985-06-01
AU2758384A (en) 1984-11-08
FR2545354A1 (fr) 1984-11-09
DE3316510A1 (de) 1984-11-08
CA1220424A (en) 1987-04-14
ES8505542A1 (es) 1985-06-01
ATE24835T1 (de) 1987-01-15
IT1181804B (it) 1987-09-30
FR2545354B1 (fr) 1986-09-26
DK164148B (da) 1992-05-18
EP0126315A1 (de) 1984-11-28
IL71744A0 (en) 1984-09-30
KR920000306B1 (ko) 1992-01-11
JPH0422888B2 (da) 1992-04-20
IT8448139A0 (it) 1984-05-04
PT78542B (en) 1986-07-14
IL71744A (en) 1988-04-29
DE3461988D1 (en) 1987-02-19
DK224184A (da) 1984-11-07
JPS59206305A (ja) 1984-11-22
DK164148C (da) 1992-10-26
HK75889A (en) 1989-09-29
PT78542A (en) 1984-06-01
AU562293B2 (en) 1987-06-04
BE899564A (fr) 1984-11-05

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Legal Events

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PUP Patent expired