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DK175843B1 - Polypeptider af overfladeaktive alvelolarproteiner (ASP), farmaceutisk sammensætning indeholdende polypeptidet, DNA-ekspressionssystem der koder for polypeptidet, samt fremgangsmåde til fremstilling af polypeptider med ASP-aktivitet - Google Patents

Polypeptider af overfladeaktive alvelolarproteiner (ASP), farmaceutisk sammensætning indeholdende polypeptidet, DNA-ekspressionssystem der koder for polypeptidet, samt fremgangsmåde til fremstilling af polypeptider med ASP-aktivitet Download PDF

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Publication number
DK175843B1
DK175843B1 DK199001101A DK110190A DK175843B1 DK 175843 B1 DK175843 B1 DK 175843B1 DK 199001101 A DK199001101 A DK 199001101A DK 110190 A DK110190 A DK 110190A DK 175843 B1 DK175843 B1 DK 175843B1
Authority
DK
Denmark
Prior art keywords
polypeptide
asp
polypeptides
alvelolar
surfactant
Prior art date
Application number
DK199001101A
Other languages
Danish (da)
English (en)
Other versions
DK110190A (da
DK110190D0 (da
Inventor
Bradley J Benson
Robert T White
W Schilling James Jr
Douglas Buckley
Robert M Scarborough
Barbara Cordell
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of DK110190D0 publication Critical patent/DK110190D0/da
Publication of DK110190A publication Critical patent/DK110190A/da
Application granted granted Critical
Publication of DK175843B1 publication Critical patent/DK175843B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Seasonings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
DK199001101A 1987-11-04 1990-05-03 Polypeptider af overfladeaktive alvelolarproteiner (ASP), farmaceutisk sammensætning indeholdende polypeptidet, DNA-ekspressionssystem der koder for polypeptidet, samt fremgangsmåde til fremstilling af polypeptider med ASP-aktivitet DK175843B1 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11709987A 1987-11-04 1987-11-04
US26644388A 1988-11-01 1988-11-01
PCT/US1988/003899 WO1989004326A1 (en) 1987-11-04 1988-11-02 Alveolar surfactant proteins

Publications (3)

Publication Number Publication Date
DK110190D0 DK110190D0 (da) 1990-05-03
DK110190A DK110190A (da) 1990-07-04
DK175843B1 true DK175843B1 (da) 2005-03-29

Family

ID=26814915

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199001101A DK175843B1 (da) 1987-11-04 1990-05-03 Polypeptider af overfladeaktive alvelolarproteiner (ASP), farmaceutisk sammensætning indeholdende polypeptidet, DNA-ekspressionssystem der koder for polypeptidet, samt fremgangsmåde til fremstilling af polypeptider med ASP-aktivitet

Country Status (9)

Country Link
EP (1) EP0383837B1 (de)
JP (1) JP2602968B2 (de)
KR (2) KR960010558B1 (de)
AT (1) ATE163013T1 (de)
AU (1) AU625394B2 (de)
CA (1) CA1340461C (de)
DK (1) DK175843B1 (de)
IL (1) IL88293A0 (de)
WO (1) WO1989004326A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104853A (en) * 1984-12-11 1992-04-14 California Biotechnology Inc. Alveolar surfactant proteins having cys to ser mutations
US5164369A (en) * 1988-01-06 1992-11-17 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
JPH04501204A (ja) * 1988-08-11 1992-03-05 サイオス　ノバ　インコーポレイテッド 異種タンパク発現を安定させる方法およびそれに使用するベクター
CA2063273C (en) * 1989-07-11 2002-09-24 Bradley J. Benson Surfactant compositions and methods
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
EP0733645B1 (de) * 1993-12-08 2003-03-19 Mitsubishi Pharma Corporation Neuartiges sythetisches Peptil, diese enthaltende Zusammensetzung und Arznei-Zusammensetzung und Arznei gegen das Atemnotsyndrom
DE4418936A1 (de) * 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
DE69924617T2 (de) 1998-07-24 2006-01-12 Altana Pharma Ag Immunologische Bestimmung des hydrophoben Lungensurfaktantproteins SP-C
AU5074400A (en) 1999-06-17 2001-01-09 Byk Gulden Lomberg Chemische Fabrik Gmbh Surfactant protein c esters
WO2001019392A1 (en) 1999-09-16 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
CA2463459C (en) 2001-10-11 2013-06-18 Altana Pharma Ag Novel use of pulmonary surfactant
WO2003053455A1 (en) 2001-12-12 2003-07-03 Penn State Research Foundation Surfactant prevention of lung complications from cancer chemotherapy
AU2005268755B2 (en) 2004-08-06 2011-04-07 Takeda Gmbh Composition comprising a pulmonary surfactant and a TNF-derived peptide
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
ATE538814T1 (de) 2005-01-06 2012-01-15 Discovery Lab Inc Dosierungsschema unter verwendung eines tensids zur behandlung oder verhinderung von lungendysplasien
US8221772B2 (en) 2006-09-19 2012-07-17 Discovery Laboratories Inc. Pulmonary surfactant formulations and methods for promoting mucus clearance
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
AU2009262243B2 (en) 2008-06-25 2015-01-29 Braasch Biotech Llc Compositions and methods for enhanced somatostatin immunogenicity
WO2009157926A1 (en) 2008-06-25 2009-12-30 Braasch Biotech Llc Chloramphenicol acetyl transferase (cat)-defective somatostatin fusion protein and uses thereof
CN102271666A (zh) 2008-12-10 2011-12-07 Paka肺部医药公司 用于向肺脏递送药物的方法和组合物
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation
US10441652B2 (en) 2014-08-21 2019-10-15 Braasch Biotech Llc Methods for improving immunological response in vaccinated animals
DE102016125491A1 (de) 2016-12-22 2018-06-28 Bombardier Transportation Gmbh Zugverband mit mindestens einer Aufhängungsvorrichtung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI82266C (fi) * 1982-10-19 1991-02-11 Cetus Corp Foerfarande foer framstaellning av il-2 -mutein.
WO1988003170A1 (en) * 1986-10-24 1988-05-05 Whitsett Jeffrey A Pulmonary hydrophobic surfactant-associated proteins

Also Published As

Publication number Publication date
AU625394B2 (en) 1992-07-09
KR960010558B1 (ko) 1996-08-02
EP0383837B1 (de) 1998-02-04
JPH03502095A (ja) 1991-05-16
EP0383837A4 (en) 1991-09-11
DK110190A (da) 1990-07-04
EP0383837A1 (de) 1990-08-29
DK110190D0 (da) 1990-05-03
CA1340461C (en) 1999-03-23
IL88293A0 (en) 1989-06-30
KR900700505A (ko) 1990-08-13
ATE163013T1 (de) 1998-02-15
AU2797989A (en) 1989-06-01
WO1989004326A1 (en) 1989-05-18
JP2602968B2 (ja) 1997-04-23

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