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DK175843B1 - Polypeptider af overfladeaktive alvelolarproteiner (ASP), farmaceutisk sammensætning indeholdende polypeptidet, DNA-ekspressionssystem der koder for polypeptidet, samt fremgangsmåde til fremstilling af polypeptider med ASP-aktivitet - Google Patents

Polypeptider af overfladeaktive alvelolarproteiner (ASP), farmaceutisk sammensætning indeholdende polypeptidet, DNA-ekspressionssystem der koder for polypeptidet, samt fremgangsmåde til fremstilling af polypeptider med ASP-aktivitet Download PDF

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Publication number
DK175843B1
DK175843B1 DK199001101A DK110190A DK175843B1 DK 175843 B1 DK175843 B1 DK 175843B1 DK 199001101 A DK199001101 A DK 199001101A DK 110190 A DK110190 A DK 110190A DK 175843 B1 DK175843 B1 DK 175843B1
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DK
Denmark
Prior art keywords
polypeptide
asp
polypeptides
alvelolar
surfactant
Prior art date
Application number
DK199001101A
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English (en)
Other versions
DK110190D0 (da
DK110190A (da
Inventor
Bradley J Benson
Robert T White
W Schilling James Jr
Douglas Buckley
Robert M Scarborough
Barbara Cordell
Original Assignee
Byk Gulden Lomberg Chem Fab
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Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of DK110190D0 publication Critical patent/DK110190D0/da
Publication of DK110190A publication Critical patent/DK110190A/da
Application granted granted Critical
Publication of DK175843B1 publication Critical patent/DK175843B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Seasonings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
DK199001101A 1987-11-04 1990-05-03 Polypeptider af overfladeaktive alvelolarproteiner (ASP), farmaceutisk sammensætning indeholdende polypeptidet, DNA-ekspressionssystem der koder for polypeptidet, samt fremgangsmåde til fremstilling af polypeptider med ASP-aktivitet DK175843B1 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11709987A 1987-11-04 1987-11-04
US26644388A 1988-11-01 1988-11-01
PCT/US1988/003899 WO1989004326A1 (en) 1987-11-04 1988-11-02 Alveolar surfactant proteins

Publications (3)

Publication Number Publication Date
DK110190D0 DK110190D0 (da) 1990-05-03
DK110190A DK110190A (da) 1990-07-04
DK175843B1 true DK175843B1 (da) 2005-03-29

Family

ID=26814915

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199001101A DK175843B1 (da) 1987-11-04 1990-05-03 Polypeptider af overfladeaktive alvelolarproteiner (ASP), farmaceutisk sammensætning indeholdende polypeptidet, DNA-ekspressionssystem der koder for polypeptidet, samt fremgangsmåde til fremstilling af polypeptider med ASP-aktivitet

Country Status (9)

Country Link
EP (1) EP0383837B1 (da)
JP (1) JP2602968B2 (da)
KR (2) KR960010558B1 (da)
AT (1) ATE163013T1 (da)
AU (1) AU625394B2 (da)
CA (1) CA1340461C (da)
DK (1) DK175843B1 (da)
IL (1) IL88293A0 (da)
WO (1) WO1989004326A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104853A (en) * 1984-12-11 1992-04-14 California Biotechnology Inc. Alveolar surfactant proteins having cys to ser mutations
US5164369A (en) * 1988-01-06 1992-11-17 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
AU4216689A (en) * 1988-08-11 1990-03-05 California Biotechnology, Inc. Method for stabilizing heterologous protein expression and vectors for use therein
CA2063273C (en) * 1989-07-11 2002-09-24 Bradley J. Benson Surfactant compositions and methods
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
CA2178345A1 (en) * 1993-12-08 1995-06-15 Tsunetomo Takei Novel synthetic peptide, lung surfactant containing the same, and remedy for respiratory distress syndrome
DE4418936A1 (de) * 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
AU4908799A (en) 1998-07-24 2000-02-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Determination of the hydrophobic pulmonary surfactant protein sp-c
ES2278609T3 (es) 1999-06-17 2007-08-16 Altana Pharma Ag Esteres tensioactivos de la proteina c.
WO2001019392A1 (en) 1999-09-16 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
AU2002338882B2 (en) 2001-10-11 2008-04-03 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Novel use of pulmonary surfactant
US6998384B2 (en) 2001-12-12 2006-02-14 The Penn State Research Foundation Surfactant prevention of lung complications from cancer chemotherapy
JP5108515B2 (ja) 2004-08-06 2012-12-26 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺サーファクタント及びｔｎｆ由来ペプチドを含有する組成物
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US7541331B2 (en) 2005-01-06 2009-06-02 Discovery Laboratories, Inc. Surfactant treatment regimen
RU2455021C2 (ru) 2006-09-19 2012-07-10 Дискавери Лабораториз, Инк. Композиции легочных сурфактантов и способы их применения, содействующие очищению от слизи
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
MX2010014078A (es) 2008-06-25 2011-04-11 Braasch Biotech Llc Composiciones y metodos para inmunogenecidad mejorada de somatostatina.
MX2010014082A (es) 2008-06-25 2011-04-07 Braasch Biotech Llc Proteina de fusion de somatostatina deficiente en cloranfenicol-acetil-transferasa y usos de la misma.
WO2010068754A2 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation
WO2016029013A2 (en) 2014-08-21 2016-02-25 Braasch Biotech Llc Methods for improving immunological response in vaccinated animals
DE102016125491A1 (de) 2016-12-22 2018-06-28 Bombardier Transportation Gmbh Zugverband mit mindestens einer Aufhängungsvorrichtung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56026B1 (en) * 1982-10-19 1991-03-27 Cetus Corp Cysteine-depleted muteins of biologically active proteins
EP0290516A4 (en) * 1986-10-24 1989-11-14 Jeffrey A Whitsett PROTEINS RELATED TO SURFACE-EFFECTIVE HYDROPHOBIC LUNG ACTIVE SUBSTANCES.

Also Published As

Publication number Publication date
JP2602968B2 (ja) 1997-04-23
CA1340461C (en) 1999-03-23
KR960010558B1 (ko) 1996-08-02
AU2797989A (en) 1989-06-01
EP0383837B1 (en) 1998-02-04
JPH03502095A (ja) 1991-05-16
IL88293A0 (en) 1989-06-30
AU625394B2 (en) 1992-07-09
DK110190D0 (da) 1990-05-03
WO1989004326A1 (en) 1989-05-18
ATE163013T1 (de) 1998-02-15
DK110190A (da) 1990-07-04
EP0383837A1 (en) 1990-08-29
EP0383837A4 (en) 1991-09-11
KR900700505A (ko) 1990-08-13

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