DK162018C - Fremgangsmaade til fremstilling af praeparatformer indeholdende orale antidiabetica og praeparatformer indeholdende orale antidiabetica - Google Patents

Fremgangsmaade til fremstilling af praeparatformer indeholdende orale antidiabetica og praeparatformer indeholdende orale antidiabetica

Info

Publication number: DK162018C
Authority: DK; Denmark
Prior art keywords: preparation; forms containing; containing oral; oral antidiabetics; active substance
Prior art date: 1983-06-08

Application number

DK280884A

Other languages

Danish (da)

English (en)

Other versions

DK162018B (da

DK280884D0 (da

DK280884A (da

Inventor

Rolf Brickl

Gottfried Schepky

Eckhard Rupprecht

Andreas Greischel

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-08

Filing date

1984-06-07

Publication date

1992-02-10

1984-06-07 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1984-06-07 Publication of DK280884D0 publication Critical patent/DK280884D0/da

1984-12-09 Publication of DK280884A publication Critical patent/DK280884A/da

1991-09-09 Publication of DK162018B publication Critical patent/DK162018B/da

1992-02-10 Application granted granted Critical

1992-02-10 Publication of DK162018C publication Critical patent/DK162018C/da

Links

238000000034 method Methods 0.000 title abstract 2
229940127017 oral antidiabetic Drugs 0.000 title 2
239000013543 active substance Substances 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
239000002904 solvent Substances 0.000 abstract 3
230000000694 effects Effects 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
230000004060 metabolic process Effects 0.000 abstract 1
239000003538 oral antidiabetic agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Obesity (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Plant Substances (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK280884A 1983-06-08 1984-06-07 Fremgangsmaade til fremstilling af praeparatformer indeholdende orale antidiabetica og praeparatformer indeholdende orale antidiabetica DK162018C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3320583		1983-06-08
DE19833320583 DE3320583A1 (de)	1983-06-08	1983-06-08	Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung

Publications (4)

Publication Number	Publication Date
DK280884D0 DK280884D0 (da)	1984-06-07
DK280884A DK280884A (da)	1984-12-09
DK162018B DK162018B (da)	1991-09-09
DK162018C true DK162018C (da)	1992-02-10

Family

ID=6200886

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK280884A DK162018C (da)	1983-06-08	1984-06-07	Fremgangsmaade til fremstilling af praeparatformer indeholdende orale antidiabetica og praeparatformer indeholdende orale antidiabetica

Country Status (24)

Country	Link
US (2)	US4708868A (no)
EP (1)	EP0128482B1 (no)
JP (1)	JPS6075435A (no)
KR (1)	KR910004572B1 (no)
AT (1)	ATE49886T1 (no)
AU (1)	AU562803B2 (no)
CA (1)	CA1228300A (no)
DD (1)	DD223360A5 (no)
DE (2)	DE3320583A1 (no)
DK (1)	DK162018C (no)
ES (1)	ES8601697A1 (no)
FI (1)	FI85218C (no)
GB (1)	GB2142235B (no)
GR (1)	GR82363B (no)
HK (1)	HK72287A (no)
HU (1)	HU192407B (no)
IE (1)	IE57792B1 (no)
IL (1)	IL72033A (no)
MY (1)	MY100764A (no)
NO (1)	NO168629C (no)
NZ (1)	NZ208416A (no)
PT (1)	PT78711B (no)
SG (1)	SG48087G (no)
ZA (1)	ZA844295B (no)

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CN104000779A (zh)	2007-04-23	2014-08-27	精达制药公司	促胰岛素释放肽的混悬制剂及其应用
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1983
- 1983-06-08 DE DE19833320583 patent/DE3320583A1/de not_active Withdrawn
1984
- 1984-05-31 US US06/616,010 patent/US4708868A/en not_active Expired - Lifetime
- 1984-06-01 AT AT84106271T patent/ATE49886T1/de not_active IP Right Cessation
- 1984-06-01 EP EP84106271A patent/EP0128482B1/de not_active Expired - Lifetime
- 1984-06-01 DE DE8484106271T patent/DE3481170D1/de not_active Expired - Lifetime
- 1984-06-05 IL IL72033A patent/IL72033A/xx unknown
- 1984-06-06 DD DD84263870A patent/DD223360A5/de not_active IP Right Cessation
- 1984-06-07 ZA ZA844295A patent/ZA844295B/xx unknown
- 1984-06-07 ES ES533207A patent/ES8601697A1/es not_active Expired
- 1984-06-07 HU HU842207A patent/HU192407B/hu not_active IP Right Cessation
- 1984-06-07 DK DK280884A patent/DK162018C/da not_active IP Right Cessation
- 1984-06-07 NZ NZ208416A patent/NZ208416A/en unknown
- 1984-06-07 GR GR74958A patent/GR82363B/el unknown
- 1984-06-07 CA CA000456097A patent/CA1228300A/en not_active Expired
- 1984-06-07 KR KR1019840003189A patent/KR910004572B1/ko not_active IP Right Cessation
- 1984-06-07 FI FI842295A patent/FI85218C/fi not_active IP Right Cessation
- 1984-06-07 GB GB08414528A patent/GB2142235B/en not_active Expired
- 1984-06-07 IE IE1422/84A patent/IE57792B1/en not_active IP Right Cessation
- 1984-06-07 NO NO842291A patent/NO168629C/no unknown
- 1984-06-07 JP JP59117431A patent/JPS6075435A/ja active Granted
- 1984-06-08 AU AU29241/84A patent/AU562803B2/en not_active Ceased
- 1984-06-08 PT PT78711A patent/PT78711B/pt unknown
1987
- 1987-05-30 SG SG48087A patent/SG48087G/en unknown
- 1987-07-06 MY MYPI87000950A patent/MY100764A/en unknown
- 1987-09-30 US US07/103,524 patent/US4873080A/en not_active Expired - Lifetime
- 1987-10-07 HK HK722/87A patent/HK72287A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU192407B (en)	1987-06-29
GB2142235A (en)	1985-01-16
KR910004572B1 (ko)	1991-07-06
ES533207A0 (es)	1985-11-16
PT78711B (de)	1986-10-21
CA1228300A (en)	1987-10-20
AU562803B2 (en)	1987-06-18
US4873080A (en)	1989-10-10
DK162018B (da)	1991-09-09
IE57792B1 (en)	1993-04-07
DK280884D0 (da)	1984-06-07
EP0128482A2 (de)	1984-12-19
GB2142235B (en)	1987-04-08
DE3481170D1 (de)	1990-03-08
IE841422L (en)	1984-12-08
IL72033A0 (en)	1984-10-31
HUT34349A (en)	1985-03-28
HK72287A (en)	1987-10-16
GB8414528D0 (en)	1984-07-11
MY100764A (en)	1991-02-15
SG48087G (en)	1987-08-28
FI85218C (fi)	1992-03-25
DE3320583A1 (de)	1984-12-13
FI85218B (fi)	1991-12-13
NO842291L (no)	1984-12-10
PT78711A (de)	1984-07-01
FI842295A (fi)	1984-12-09
ATE49886T1 (de)	1990-02-15
JPH0548206B2 (no)	1993-07-20
FI842295A0 (fi)	1984-06-07
KR850000241A (ko)	1985-02-26
AU2924184A (en)	1984-12-13
EP0128482B1 (de)	1990-01-31
US4708868A (en)	1987-11-24
EP0128482A3 (en)	1986-06-25
JPS6075435A (ja)	1985-04-27
DD223360A5 (de)	1985-06-12
IL72033A (en)	1987-08-31
NO168629B (no)	1991-12-09
DK280884A (da)	1984-12-09
NO168629C (no)	1992-03-18
ZA844295B (en)	1986-02-26
GR82363B (no)	1984-12-13
NZ208416A (en)	1987-06-30
ES8601697A1 (es)	1985-11-16

Publication	Publication Date	Title
DK162018C (da)	1992-02-10	Fremgangsmaade til fremstilling af praeparatformer indeholdende orale antidiabetica og praeparatformer indeholdende orale antidiabetica
DK162019C (da)	1992-02-10	Fremgangsmaade til fremstilling af orale praeparatformer indeholdende antidiabetica og orale praeparatformer indeholdende antidiabetica

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