DK1657310T3 - Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf - Google Patents

Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf

Info

Publication number: DK1657310T3
Authority: DK; Denmark
Prior art keywords: derivatives; preparation; dihydroxy esters; dihydroxy; esters
Prior art date: 2000-05-09

Application number

DK06002032T

Other languages

English (en)

Inventor

Robert Antony Holt

Christopher David Reeve

Andrew John Blacker

Original Assignee

Astrazeneca Uk Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-09

Filing date

2001-05-01

Publication date

2007-10-29

2001-05-01 Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd

2007-10-29 Application granted granted Critical

2007-10-29 Publication of DK1657310T3 publication Critical patent/DK1657310T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK06002032T 2000-05-09 2001-05-01 Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf DK1657310T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0011120.3A GB0011120D0 (en)	2000-05-09	2000-05-09	Process
GB0011120		2001-05-01

Publications (1)

Publication Number	Publication Date
DK1657310T3 true DK1657310T3 (da)	2007-10-29

Family

ID=9891211

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK01925699T DK1282719T3 (da)	2000-05-09	2001-05-01	Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf
DK06002032T DK1657310T3 (da)	2000-05-09	2001-05-01	Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf
DK06019415.6T DK1726658T3 (da)	2000-05-09	2001-05-01	Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK01925699T DK1282719T3 (da)	2000-05-09	2001-05-01	Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK06019415.6T DK1726658T3 (da)	2000-05-09	2001-05-01	Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf

Country Status (34)

Country	Link
US (4)	US7157255B2 (da)
EP (3)	EP1282719B1 (da)
JP (1)	JP4733901B2 (da)
KR (2)	KR100914675B1 (da)
CN (1)	CN1196793C (da)
AR (2)	AR028074A1 (da)
AT (3)	ATE330020T1 (da)
AU (2)	AU5238301A (da)
BR (1)	BR0110667A (da)
CA (2)	CA2408004C (da)
CY (3)	CY1105376T1 (da)
CZ (3)	CZ302674B6 (da)
DE (3)	DE60129865T2 (da)
DK (3)	DK1282719T3 (da)
EE (1)	EE05062B1 (da)
ES (3)	ES2264981T3 (da)
GB (1)	GB0011120D0 (da)
HK (3)	HK1051708A1 (da)
HU (1)	HUP0302216A3 (da)
IL (4)	IL152608A0 (da)
IS (1)	IS2290B (da)
MX (1)	MXPA02010955A (da)
MY (1)	MY127751A (da)
NO (1)	NO20025377L (da)
NZ (1)	NZ522407A (da)
PL (3)	PL208377B1 (da)
PT (3)	PT1726658E (da)
RU (1)	RU2266961C2 (da)
SI (3)	SI1657310T1 (da)
SK (2)	SK287524B6 (da)
TW (1)	TWI240753B (da)
UA (1)	UA73774C2 (da)
WO (1)	WO2001085975A1 (da)
ZA (1)	ZA200208937B (da)

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ATE448209T1 (de)	2002-12-16	2009-11-15	Astrazeneca Uk Ltd	Verfahren zur herstellung von pyrimidinverbindungen
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CN102373250B (zh) *	2011-11-08	2012-08-22	张家港市信谊化工有限公司	阿伐他汀钙侧链中间体的制备方法
CN102618596A (zh) *	2012-03-20	2012-08-01	中国药科大学	一种非水相体系中生物转化制备关附庚素的方法
WO2014203045A1 (en)	2013-06-20	2014-12-24	Lupin Limited	A novel, green and cost effective process for synthesis of tert-butyl (3r,5s)-6-oxo-3,5-dihydroxy-3,5-o-isopropylidene-hexanoate
CN105503816B (zh) *	2016-02-17	2018-02-13	中节能万润股份有限公司	一种固体(4R‑cis)‑6‑甲酰基‑2,2‑二甲基‑1,3‑二氧己环‑4‑乙酸叔丁酯的制备方法
CN108530416B (zh) *	2017-11-02	2020-05-12	江苏阿尔法药业有限公司	一种瑞舒伐他汀中间体的制备方法
CN109574830B (zh) *	2019-01-04	2021-04-13	浙江宏元药业股份有限公司	一种瑞舒伐他汀钙中间体及其制备方法和应用
KR102384854B1 (ko)	2021-06-15	2022-04-11	한대성	풀빅산 및 일라이트를 이용한 침대

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2000
- 2000-05-09 GB GBGB0011120.3A patent/GB0011120D0/en not_active Ceased
2001
- 2001-01-05 UA UA2002129795A patent/UA73774C2/uk unknown
- 2001-05-01 AT AT01925699T patent/ATE330020T1/de active
- 2001-05-01 CZ CZ20110204A patent/CZ302674B6/cs not_active IP Right Cessation
- 2001-05-01 IL IL15260801A patent/IL152608A0/xx unknown
- 2001-05-01 WO PCT/GB2001/001915 patent/WO2001085975A1/en active Application Filing
- 2001-05-01 HU HU0302216A patent/HUP0302216A3/hu unknown
- 2001-05-01 DE DE60129865T patent/DE60129865T2/de not_active Expired - Lifetime
- 2001-05-01 AT AT06002032T patent/ATE369437T1/de active
- 2001-05-01 BR BR0110667-8A patent/BR0110667A/pt not_active IP Right Cessation
- 2001-05-01 ES ES01925699T patent/ES2264981T3/es not_active Expired - Lifetime
- 2001-05-01 PL PL387243A patent/PL208377B1/pl not_active IP Right Cessation
- 2001-05-01 SI SI200130758T patent/SI1657310T1/sl unknown
- 2001-05-01 AT AT06019415T patent/ATE458823T1/de active
- 2001-05-01 JP JP2001582563A patent/JP4733901B2/ja not_active Expired - Lifetime
- 2001-05-01 DK DK01925699T patent/DK1282719T3/da active
- 2001-05-01 EE EEP200200628A patent/EE05062B1/xx not_active IP Right Cessation
- 2001-05-01 ES ES06019415T patent/ES2340190T3/es not_active Expired - Lifetime
- 2001-05-01 SI SI200130963T patent/SI1726658T1/sl unknown
- 2001-05-01 MX MXPA02010955A patent/MXPA02010955A/es active IP Right Grant
- 2001-05-01 AU AU5238301A patent/AU5238301A/xx active Pending
- 2001-05-01 PL PL387244A patent/PL208379B1/pl not_active IP Right Cessation
- 2001-05-01 EP EP01925699A patent/EP1282719B1/en not_active Expired - Lifetime
- 2001-05-01 DE DE60120685T patent/DE60120685T2/de not_active Expired - Lifetime
- 2001-05-01 SK SK5088-2008A patent/SK287524B6/sk not_active IP Right Cessation
- 2001-05-01 ES ES06002032T patent/ES2289722T3/es not_active Expired - Lifetime
- 2001-05-01 SI SI200130591T patent/SI1282719T1/sl unknown
- 2001-05-01 PT PT06019415T patent/PT1726658E/pt unknown
- 2001-05-01 CA CA2408004A patent/CA2408004C/en not_active Expired - Fee Related
- 2001-05-01 EP EP06019415A patent/EP1726658B1/en not_active Expired - Lifetime
- 2001-05-01 NZ NZ522407A patent/NZ522407A/en not_active IP Right Cessation
- 2001-05-01 EP EP06002032A patent/EP1657310B1/en not_active Expired - Lifetime
- 2001-05-01 RU RU2002132884/13A patent/RU2266961C2/ru not_active IP Right Cessation
- 2001-05-01 DK DK06002032T patent/DK1657310T3/da active
- 2001-05-01 CN CNB018124895A patent/CN1196793C/zh not_active Expired - Lifetime
- 2001-05-01 SK SK1589-2002A patent/SK286746B6/sk not_active IP Right Cessation
- 2001-05-01 PT PT06002032T patent/PT1657310E/pt unknown
- 2001-05-01 KR KR1020027014987A patent/KR100914675B1/ko not_active IP Right Cessation
- 2001-05-01 CZ CZ20023675A patent/CZ302632B6/cs not_active IP Right Cessation
- 2001-05-01 AU AU2001252383A patent/AU2001252383B2/en not_active Ceased
- 2001-05-01 CZ CZ20110205A patent/CZ302675B6/cs not_active IP Right Cessation
- 2001-05-01 DK DK06019415.6T patent/DK1726658T3/da active
- 2001-05-01 PT PT01925699T patent/PT1282719E/pt unknown
- 2001-05-01 KR KR1020087005996A patent/KR100996977B1/ko not_active IP Right Cessation
- 2001-05-01 US US10/275,092 patent/US7157255B2/en not_active Expired - Lifetime
- 2001-05-01 PL PL359336A patent/PL208359B1/pl not_active IP Right Cessation
- 2001-05-01 DE DE60141424T patent/DE60141424D1/de not_active Expired - Lifetime
- 2001-05-01 CA CA002677945A patent/CA2677945A1/en not_active Abandoned
- 2001-05-03 AR ARP010102091A patent/AR028074A1/es active IP Right Grant
- 2001-05-04 TW TW090110741A patent/TWI240753B/zh not_active IP Right Cessation
- 2001-05-08 MY MYPI20012105A patent/MY127751A/en unknown
2002
- 2002-11-03 IL IL152608A patent/IL152608A/en not_active IP Right Cessation
- 2002-11-04 ZA ZA200208937A patent/ZA200208937B/en unknown
- 2002-11-07 IS IS6609A patent/IS2290B/is unknown
- 2002-11-08 NO NO20025377A patent/NO20025377L/no not_active Application Discontinuation
2003
- 2003-06-05 HK HK03103991A patent/HK1051708A1/xx not_active IP Right Cessation
2006
- 2006-04-27 US US11/412,047 patent/US7416865B2/en not_active Expired - Lifetime
- 2006-09-12 CY CY20061101301T patent/CY1105376T1/el unknown
- 2006-09-22 HK HK06110633A patent/HK1090090A1/xx not_active IP Right Cessation
2007
- 2007-02-09 HK HK07101586.1A patent/HK1096998A1/xx not_active IP Right Cessation
- 2007-10-05 CY CY20071101270T patent/CY1106910T1/el unknown
2008
- 2008-07-23 US US12/178,424 patent/US7732171B2/en not_active Expired - Fee Related
- 2008-08-12 IL IL193405A patent/IL193405A/en not_active IP Right Cessation
- 2008-08-12 IL IL193404A patent/IL193404A/en not_active IP Right Cessation
- 2008-09-15 AR ARP080104001A patent/AR070946A2/es not_active Application Discontinuation
2010
- 2010-04-27 US US12/768,459 patent/US7888083B2/en not_active Expired - Fee Related
- 2010-04-27 CY CY20101100376T patent/CY1109991T1/el unknown

Also Published As

Publication number	Publication date
EP1282719A1 (en)	2003-02-12
PT1726658E (pt)	2010-04-15
CZ302674B6 (cs)	2011-08-24
ES2264981T3 (es)	2007-02-01
CA2677945A1 (en)	2001-11-15
US7888083B2 (en)	2011-02-15
US20080280336A1 (en)	2008-11-13
IL193405A0 (en)	2009-02-11
PL359336A1 (en)	2004-08-23
DE60129865T2 (de)	2008-05-08
DE60120685D1 (de)	2006-07-27
KR20030032949A (ko)	2003-04-26
MXPA02010955A (es)	2003-05-27
RU2266961C2 (ru)	2005-12-27
DE60120685T2 (de)	2007-06-14
EE05062B1 (et)	2008-08-15
CZ20023675A3 (cs)	2003-02-12
DK1726658T3 (da)	2010-05-17
PT1282719E (pt)	2006-09-29
PL208377B1 (pl)	2011-04-29
AU5238301A (en)	2001-11-20
PT1657310E (pt)	2007-09-26
CZ302675B6 (cs)	2011-08-24
IL193404A (en)	2010-04-29
DK1282719T3 (da)	2006-10-02
CY1106910T1 (el)	2012-09-26
KR100996977B1 (ko)	2010-11-26
ES2289722T3 (es)	2008-02-01
US7732171B2 (en)	2010-06-08
CY1109991T1 (el)	2014-09-10
US20030134900A1 (en)	2003-07-17
EP1282719B1 (en)	2006-06-14
PL208359B1 (pl)	2011-04-29
EE200200628A (et)	2004-04-15
PL208379B1 (pl)	2011-04-29
US7416865B2 (en)	2008-08-26
MY127751A (en)	2006-12-29
DE60129865D1 (de)	2007-09-20
UA73774C2 (en)	2005-09-15
BR0110667A (pt)	2003-03-25
DE60141424D1 (de)	2010-04-08
SK286746B6 (sk)	2009-04-06
IL193405A (en)	2010-04-29
CY1105376T1 (el)	2010-04-28
KR100914675B1 (ko)	2009-08-28
JP2003532427A (ja)	2003-11-05
HK1090090A1 (en)	2006-12-15
US7157255B2 (en)	2007-01-02
HK1096998A1 (en)	2007-06-15
CN1440461A (zh)	2003-09-03
SK287524B6 (sk)	2011-01-04
SI1726658T1 (sl)	2010-05-31
ZA200208937B (en)	2003-08-28
US20100209984A1 (en)	2010-08-19
SI1282719T1 (sl)	2006-10-31
EP1657310A1 (en)	2006-05-17
KR20080042129A (ko)	2008-05-14
SI1657310T1 (sl)	2007-12-31
EP1657310B1 (en)	2007-08-08
NO20025377L (no)	2003-01-07
IL193404A0 (en)	2009-02-11
ES2340190T3 (es)	2010-05-31
IL152608A0 (en)	2003-06-24
CZ302632B6 (cs)	2011-08-10
US20060194297A1 (en)	2006-08-31
EP1726658A3 (en)	2008-12-24
CA2408004A1 (en)	2001-11-15
AU2001252383B2 (en)	2005-04-14
AR070946A2 (es)	2010-05-19
CA2408004C (en)	2010-04-13
CN1196793C (zh)	2005-04-13
NO20025377D0 (no)	2002-11-08
ATE330020T1 (de)	2006-07-15
ATE369437T1 (de)	2007-08-15
EP1726658B1 (en)	2010-02-24
JP4733901B2 (ja)	2011-07-27
EP1726658A2 (en)	2006-11-29
IS6609A (is)	2002-11-07
SK15892002A3 (sk)	2003-04-01
HUP0302216A3 (en)	2011-03-28
AR028074A1 (es)	2003-04-23
TWI240753B (en)	2005-10-01
ATE458823T1 (de)	2010-03-15
IL152608A (en)	2009-05-04
WO2001085975A1 (en)	2001-11-15
HK1051708A1 (en)	2003-08-15
IS2290B (is)	2007-10-15
NZ522407A (en)	2004-06-25
HUP0302216A2 (hu)	2003-10-28
GB0011120D0 (en)	2000-06-28

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