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DK153440C - Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat - Google Patents

Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat

Info

Publication number
DK153440C
DK153440C DK499477A DK499477A DK153440C DK 153440 C DK153440 C DK 153440C DK 499477 A DK499477 A DK 499477A DK 499477 A DK499477 A DK 499477A DK 153440 C DK153440 C DK 153440C
Authority
DK
Denmark
Prior art keywords
ergotpeptidalkaloid
preparing
procedure
preparation
national pharmaceutical
Prior art date
Application number
DK499477A
Other languages
English (en)
Other versions
DK153440B (da
DK499477A (da
Inventor
Moise Azria
Thomas Cavanak
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK499477A publication Critical patent/DK499477A/da
Publication of DK153440B publication Critical patent/DK153440B/da
Application granted granted Critical
Publication of DK153440C publication Critical patent/DK153440C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/48Ergoline derivatives, e.g. lysergic acid, ergotamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01DMEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D2207/00Indexing scheme relating to details of indicating measuring values
    • G01D2207/10Displays which are primarily used in aircraft or display aircraft-specific information

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK499477A 1976-11-19 1977-11-10 Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat DK153440C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1457576 1976-11-19
CH1457576 1976-11-19
CH698977 1977-06-07
CH698977 1977-06-07

Publications (3)

Publication Number Publication Date
DK499477A DK499477A (da) 1978-05-20
DK153440B DK153440B (da) 1988-07-18
DK153440C true DK153440C (da) 1989-01-02

Family

ID=25700540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK499477A DK153440C (da) 1976-11-19 1977-11-10 Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat

Country Status (27)

Country Link
US (2) US4462983A (da)
JP (1) JPS5366440A (da)
AT (1) AT368881B (da)
AU (1) AU520754B2 (da)
CA (1) CA1103585A (da)
CS (2) CS228502B2 (da)
CY (1) CY1266A (da)
DE (2) DE2750090A1 (da)
DK (1) DK153440C (da)
ES (1) ES464275A1 (da)
FI (1) FI773376A (da)
FR (1) FR2371454A1 (da)
GB (1) GB1592563A (da)
GR (1) GR65229B (da)
HK (1) HK85984A (da)
HU (1) HU185924B (da)
IE (1) IE46167B1 (da)
IL (1) IL53419A (da)
KE (1) KE3453A (da)
MY (1) MY8400055A (da)
NL (1) NL187892C (da)
NO (1) NO773839L (da)
NZ (1) NZ185711A (da)
PH (1) PH23643A (da)
PT (1) PT67292B (da)
SE (1) SE451944B (da)
SG (1) SG61784G (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4284648A (en) * 1979-08-03 1981-08-18 The University Of Kentucky Research Foundation Nasal administration of propranolol
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
FI81258C (fi) * 1982-02-01 1990-10-10 Sandoz Ag Foerfarande foer framstaellning av en farmaceutisk komposition foer nasal administration.
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
GB8413795D0 (en) * 1984-05-30 1984-07-04 Sandoz Ltd Organic compounds
GB8426922D0 (en) * 1984-10-24 1984-11-28 Sandoz Ltd Galenic formulation
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
FR2628638B1 (fr) * 1985-03-06 1992-12-18 Sandoz Lab Dispositif de pulverisation par voie nasale d'une dose unitaire de medicament en solution
JPS61263918A (ja) * 1985-05-16 1986-11-21 Banyu Pharmaceut Co Ltd 経皮吸収用製剤
ATE78158T1 (de) * 1985-05-22 1992-08-15 Liposome Technology Inc Verfahren und system zum einatmen von liposomen.
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
US4897256A (en) * 1986-11-25 1990-01-30 Abbott Laboratories LHRH analog formulations
DE3710216A1 (de) * 1987-03-27 1988-10-06 Rentschler Arzneimittel Verwendung von dihydroergotamin und seinen salzen zur lokalen behandlung trophischer stoerungen
DE68915203T2 (de) * 1988-03-22 1994-09-22 Fisons Plc, Ipswich, Suffolk Pharmazeutische Mischungen.
US4929640A (en) * 1988-04-04 1990-05-29 George D. McAdory Medicaments intended for combined use in the improvement of lymphocyte function
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
IT1247472B (it) * 1991-05-31 1994-12-17 Fidia Spa Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
WO1993025193A1 (en) * 1992-06-12 1993-12-23 Teijin Limited Pharmaceutical preparation for intra-airway administration
ATE222754T1 (de) * 1992-06-12 2002-09-15 Teijin Ltd Ultrafeines pulver zur inhalation und dessen herstellung
ATE290864T1 (de) * 1993-03-26 2005-04-15 Franciscus Wilhelmus He Merkus Pharmazeutische zusammensetzungen zur intranasalen verabreichung von dihydroergotamin
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
KR100389080B1 (ko) * 1994-12-22 2003-10-17 아스트라제네카 악티에볼라그 부갑상선호르몬(pth)을포함하는흡입용치료제제
PL320856A1 (en) 1994-12-22 1997-11-10 Astra Ab Aerosol drug preparations
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
JP2003535042A (ja) * 2000-01-20 2003-11-25 バジリア ファルマスーチカ アーゲー 鼻腔に投与可能な環式ペプチド組成物
US20030008005A1 (en) * 2001-07-05 2003-01-09 R.T. Alamo Ventures, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
GB0208742D0 (en) * 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
GB2405334B (en) * 2002-04-17 2006-02-15 Nektar Therapeutics Uk Ltd Particulate materials
PL2425820T3 (pl) 2007-02-11 2015-08-31 Map Pharmaceuticals Inc Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych
US20120000941A1 (en) * 2010-06-30 2012-01-05 Inspire Pharmaceuticals, Inc. Medicine dispenser
NZ741171A (en) 2015-09-10 2022-01-28 Impel Neuropharma Inc In-line nasal delivery device
RU2019143750A (ru) * 2017-07-02 2021-08-03 Др. Редди'С Лабораториз Лтд. Назальные лекарственные формы дигидроэрготамина
US20190209463A1 (en) 2018-01-05 2019-07-11 Impel Neuropharma, Inc. Intranasal delivery of dihydroergotamine by precision olfactory device
GB2581431A (en) * 2018-12-11 2020-08-19 Satsuma Pharmaceuticals Inc Compositions, devices, and methods for treating or preventing headaches
CA3122396A1 (en) 2018-12-11 2020-06-18 Satsuma Pharmaceuticals, Inc. Compositions, devices, and methods for treating or preventing headaches

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063512A (en) * 1962-11-30 1967-03-30 Benger Lab Ltd Aerosols
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
US4076715A (en) * 1972-09-26 1978-02-28 Sandoz Ltd. 13-Bromo lysergic acid compounds
CA990287A (en) * 1972-09-26 1976-06-01 Sandoz Patents Limited 13-bromo-lysergic acid compounds
NL7314066A (da) * 1972-10-18 1974-04-22
US3896228A (en) * 1973-03-15 1975-07-22 Sandoz Ltd Method for treating nephrises
US3883655A (en) * 1973-10-11 1975-05-13 Sandoz Ltd Ergocornine or 2-bromo-{60 -ergocyptine in the treatment of parkinsonism
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
EP0119493A1 (en) * 1983-03-16 1984-09-26 American Cyanamid Company Use of copolymers of 2-acrylamido-2-methylpropane sulfonic acid for improving retention and dewatering in the manufacture of paper

Also Published As

Publication number Publication date
FR2371454B1 (da) 1980-08-22
SE7712693L (sv) 1978-05-20
PH23643A (en) 1989-09-27
NL7712552A (nl) 1978-05-23
FI773376A (fi) 1978-05-20
US4462983A (en) 1984-07-31
IE46167L (en) 1978-05-19
DE2750090A1 (de) 1978-06-01
AU520754B2 (en) 1982-02-25
NL187892B (nl) 1991-09-16
GB1592563A (en) 1981-07-08
DK153440B (da) 1988-07-18
NL187892C (nl) 1992-02-17
AT368881B (de) 1982-11-25
ATA825477A (de) 1982-04-15
SG61784G (en) 1985-03-15
IL53419A (en) 1982-04-30
AU3078377A (en) 1979-05-24
ES464275A1 (es) 1978-12-16
IL53419A0 (en) 1978-01-31
SE451944B (sv) 1987-11-09
HU185924B (en) 1985-03-28
PT67292A (fr) 1977-12-01
KE3453A (en) 1984-10-05
JPS6313965B2 (da) 1988-03-29
FR2371454A1 (fr) 1978-06-16
CS228502B2 (en) 1984-04-16
MY8400055A (en) 1984-12-31
PT67292B (fr) 1979-11-12
NO773839L (no) 1978-05-22
DE2802113A1 (de) 1979-07-26
IE46167B1 (en) 1983-03-09
JPS5366440A (en) 1978-06-13
US4758423A (en) 1988-07-19
CY1266A (en) 1984-11-23
CA1103585A (en) 1981-06-23
HK85984A (en) 1984-11-16
GR65229B (en) 1980-07-30
NZ185711A (en) 1980-04-28
DK499477A (da) 1978-05-20
CS228523B2 (en) 1984-05-14

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Legal Events

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PUP Patent expired