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DK1385515T3 - Spiropyrazole forbindelser - Google Patents

Spiropyrazole forbindelser

Info

Publication number
DK1385515T3
DK1385515T3 DK02739163T DK02739163T DK1385515T3 DK 1385515 T3 DK1385515 T3 DK 1385515T3 DK 02739163 T DK02739163 T DK 02739163T DK 02739163 T DK02739163 T DK 02739163T DK 1385515 T3 DK1385515 T3 DK 1385515T3
Authority
DK
Denmark
Prior art keywords
spiropyrazole
compounds
spiropyrazole compounds
whereinz
compound
Prior art date
Application number
DK02739163T
Other languages
English (en)
Inventor
Gary Lee
R Richard Goehring
Donald Kyle
Parviz Gharagozloo
Sam Victory
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of DK1385515T3 publication Critical patent/DK1385515T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Dental Preparations (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK02739163T 2001-04-18 2002-04-18 Spiropyrazole forbindelser DK1385515T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28467501P 2001-04-18 2001-04-18
PCT/US2002/012376 WO2002085355A1 (en) 2001-04-18 2002-04-18 Spiropyrazole compounds

Publications (1)

Publication Number Publication Date
DK1385515T3 true DK1385515T3 (da) 2008-10-27

Family

ID=23091099

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02739163T DK1385515T3 (da) 2001-04-18 2002-04-18 Spiropyrazole forbindelser

Country Status (28)

Country Link
US (2) US6635653B2 (da)
EP (1) EP1385515B1 (da)
JP (1) JP4342181B2 (da)
KR (1) KR100628292B1 (da)
CN (1) CN1516584A (da)
AT (1) ATE403429T1 (da)
AU (1) AU2002311833B2 (da)
BR (1) BR0209127A (da)
CA (1) CA2444634C (da)
CY (1) CY1108454T1 (da)
CZ (1) CZ20032849A3 (da)
DE (1) DE60228071D1 (da)
DK (1) DK1385515T3 (da)
ES (1) ES2312584T3 (da)
HK (1) HK1062885A1 (da)
HU (1) HUP0401333A3 (da)
IL (2) IL158485A0 (da)
MX (1) MXPA03009604A (da)
NO (1) NO20034660L (da)
NZ (1) NZ528978A (da)
PL (1) PL367263A1 (da)
PT (1) PT1385515E (da)
RU (1) RU2299883C2 (da)
SI (1) SI1385515T1 (da)
UA (1) UA74439C2 (da)
WO (1) WO2002085355A1 (da)
YU (1) YU82403A (da)
ZA (1) ZA200308103B (da)

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US20100009929A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
US20100028339A1 (en) * 2004-03-29 2010-02-04 Cheng Jin Q Compositions including triciribine and trastuzumab and methods of use thereof
US20110008327A1 (en) * 2004-03-29 2011-01-13 Cheng Jin Q Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
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ES2534546T3 (es) 2007-08-31 2015-04-24 Purdue Pharma Lp Compuestos de piperidina, de tipo quinoxalina sustituida, y usos de los mismos
RU2500678C2 (ru) 2008-07-21 2013-12-10 Пэдью Фарма Л.П. Замещенные хиноксалинового типа мостиковые пиперидиновые соединения и их применение
UA107943C2 (en) * 2009-11-16 2015-03-10 Lilly Co Eli Compounds of spiropiperidines as antagonists of the orl-1 receptors
EP2654751B1 (en) 2010-12-22 2016-11-23 Purdue Pharma L.P. Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof
WO2013080036A1 (en) 2011-12-01 2013-06-06 Purdue Pharma L.P. Azetidine-substituted quinoxaline-type piperidine compounds and uses thereof
US9085561B2 (en) 2012-07-30 2015-07-21 Purdue Pharma L.P. Cyclic urea- or lactam-substituted quinoxaline-type piperidines as ORL-1 modulators
US10118927B2 (en) 2012-12-27 2018-11-06 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
WO2014102588A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
WO2014102589A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Quinazolin-4(3h)-one-type piperidine compounds and uses thereof
WO2014102594A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US9040533B2 (en) 2012-12-27 2015-05-26 Purdue Pharma L.P. Oxime-substituted-quinoxaline-type piperidine compounds as ORL-1 modulators
BR112019001398A2 (pt) 2016-07-29 2019-05-07 Janssen Pharmaceutica Nv métodos para tratamento de câncer de próstata
CN111825681A (zh) * 2020-07-07 2020-10-27 扬州大学 一种合成(e)-亚苄基螺吡唑吡咯嗪酮类化合物的方法

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Also Published As

Publication number Publication date
RU2299883C2 (ru) 2007-05-27
US20030027834A1 (en) 2003-02-06
JP4342181B2 (ja) 2009-10-14
PT1385515E (pt) 2008-09-15
CA2444634A1 (en) 2002-10-31
EP1385515B1 (en) 2008-08-06
IL158485A0 (en) 2004-05-12
NO20034660D0 (no) 2003-10-17
HUP0401333A2 (hu) 2004-10-28
NZ528978A (en) 2004-06-25
NO20034660L (no) 2003-12-17
MXPA03009604A (es) 2004-04-02
YU82403A (sh) 2006-08-17
HK1062885A1 (en) 2004-12-03
BR0209127A (pt) 2006-03-21
DE60228071D1 (de) 2008-09-18
RU2003133455A (ru) 2005-05-10
KR100628292B1 (ko) 2006-09-27
CZ20032849A3 (en) 2004-03-17
WO2002085355A1 (en) 2002-10-31
HUP0401333A3 (en) 2004-11-29
CN1516584A (zh) 2004-07-28
UA74439C2 (uk) 2005-12-15
ZA200308103B (en) 2004-10-18
PL367263A1 (en) 2005-02-21
ATE403429T1 (de) 2008-08-15
AU2002311833B2 (en) 2005-04-28
ES2312584T3 (es) 2009-03-01
CY1108454T1 (el) 2014-04-09
IL158485A (en) 2009-09-01
US20040087641A1 (en) 2004-05-06
EP1385515A1 (en) 2004-02-04
JP2004531531A (ja) 2004-10-14
US6635653B2 (en) 2003-10-21
CA2444634C (en) 2011-06-07
SI1385515T1 (sl) 2008-12-31
KR20040008159A (ko) 2004-01-28
EP1385515A4 (en) 2004-06-30

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