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DK138419B - Fremgangsmåde til fremstilling af 1alfa-hydroxycholecalciferol. - Google Patents

Fremgangsmåde til fremstilling af 1alfa-hydroxycholecalciferol.

Info

Publication number
DK138419B
DK138419B DK601072AA DK601072A DK138419B DK 138419 B DK138419 B DK 138419B DK 601072A A DK601072A A DK 601072AA DK 601072 A DK601072 A DK 601072A DK 138419 B DK138419 B DK 138419B
Authority
DK
Denmark
Prior art keywords
hydroxycholecalciferol
1alpha
preparation
Prior art date
Application number
DK601072AA
Other languages
English (en)
Other versions
DK138419C (da
Inventor
Hector Floyd Deluca
Heinrich Konstantin Schnoes
Michael Francis Holick
Erich Joseph Semmler
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22757377&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK138419(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Priority to DK144275A priority Critical patent/DK137163B/da
Priority to DK7577A priority patent/DK140946B/da
Publication of DK138419B publication Critical patent/DK138419B/da
Application granted granted Critical
Publication of DK138419C publication Critical patent/DK138419C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK601072AA 1971-12-02 1972-12-01 Fremgangsmåde til fremstilling af 1alfa-hydroxycholecalciferol. DK138419B (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK144275A DK137163B (da) 1971-12-02 1975-04-04 Vitaminholdigt dyrefoder.
DK7577A DK140946B (da) 1971-12-02 1977-01-07 1alfa, 3beta-diacetoxy-cholesta-5,7-dien til anvendelse som mellemprodukt ved fremstilling af 1alfa-hydroxycholecalciferol.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20430571A 1971-12-02 1971-12-02

Publications (2)

Publication Number Publication Date
DK138419B true DK138419B (da) 1978-09-04
DK138419C DK138419C (da) 1979-02-12

Family

ID=22757377

Family Applications (1)

Application Number Title Priority Date Filing Date
DK601072AA DK138419B (da) 1971-12-02 1972-12-01 Fremgangsmåde til fremstilling af 1alfa-hydroxycholecalciferol.

Country Status (9)

Country Link
US (1) US3741996A (da)
JP (1) JPS5654315B2 (da)
CA (1) CA966828A (da)
CH (2) CH579042A5 (da)
DE (1) DE2259661C3 (da)
DK (1) DK138419B (da)
FR (1) FR2162113B1 (da)
GB (1) GB1359407A (da)
NL (1) NL159093B (da)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670190A (en) * 1973-01-10 1987-06-02 Hesse Robert H 1-α-hydroxy vitamin D compounds and process for preparing same
US5472957A (en) * 1973-01-10 1995-12-05 Research Institute For Medicine And Chemistry Chemical compounds and process
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
ZA74158B (en) * 1973-01-10 1975-03-26 Res Inst Medicine Chem Chemical process
US3887545A (en) * 1973-11-12 1975-06-03 Hoffmann La Roche Synthesis of 1{60 -hydroxylated cholesterol derivatives
US3879548A (en) * 1974-01-21 1975-04-22 Wisconsin Alumni Res Found Method of treating milk fever in dairy cattle with 1-alpha-hydroxycholecalciferol
JPS5119752A (en) * 1974-08-07 1976-02-17 Masayuki Ishikawa 1 arufua* 2 arufuaa jihidorokishikorekarushifuerooruno seiho
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4035493A (en) * 1975-06-09 1977-07-12 Wisconsin Alumni Research Foundation Rodenticide
JPS5265261A (en) * 1975-11-27 1977-05-30 Teijin Ltd Synthesis of 1alpha-hyaroxy-provitamine d compounds
JPS5265262A (en) * 1975-11-27 1977-05-30 Teijin Ltd Synthesis of 1alpha acyloxy-provitamine d compounds
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 1α―ヒドロキシビタミンD類軟カプセルの製造方法
JPS53147051A (en) * 1977-05-24 1978-12-21 Teijin Ltd 1alpha-hydroxy-24-dehydro-vitamin d3 and its preparation
IT1106130B (it) * 1977-06-13 1985-11-11 Merck & Co Inc Derivati di 24-deidrovitamina d3 e loro preparazione
US4230700A (en) * 1977-12-07 1980-10-28 The Procter & Gamble Company Methods for inhibiting mobilization of calcium phosphate in animal tissue
US4330537A (en) * 1977-12-07 1982-05-18 The Procter & Gamble Company Compositions for inhibiting mobilization of calcium phosphate in animal tissue
JPS557215A (en) * 1978-06-30 1980-01-19 Teijin Ltd Preparation of active vitamin d3 or its oh-protected derivative and/or its corresponding previtamin d3 or its oh-protected derivative
US4201881A (en) * 1979-03-28 1980-05-06 Wisconsin Alumni Research Foundation 24,24-Difluoro-1α,25-dihydroxycholecalciferol
JPS5626820A (en) * 1979-08-10 1981-03-16 Chugai Pharmaceut Co Ltd Immunosuppressing agent
JPS5626819A (en) * 1979-08-10 1981-03-16 Chugai Pharmaceut Co Ltd Preventive for hypoimmunity
IL59221A0 (en) * 1980-01-25 1980-05-30 Yeda Res & Dev Method of improving the shell quality of poultry eggs
US4254045A (en) * 1980-04-21 1981-03-03 Wisconsin Alumni Research Foundation 1α-Hydroxy-2β-fluorocholecalciferol
EP0078704B1 (en) * 1981-11-02 1987-04-29 Research Institute For Medicine And Chemistry Inc. Intermediates in the synthesis of vitamin d derivatives
DE3590020T1 (de) * 1984-01-30 1986-01-23 Wisconsin Alumni Research Foundation, Madison, Wis. In der Seitenkette ungesättigte 1-Hydroxyvitamin D-Verbindungen
US5120722A (en) * 1984-02-08 1992-06-09 Hoffmann-La Roche Inc. Trihydroxy-cholecacliferol and trihydroxy-ergocalciferol for treating leukemia
US4588716A (en) * 1984-05-04 1986-05-13 Wisconsin Alumni Research Foundation Method for treating metabolic bone disease in mammals
US5316770A (en) * 1989-02-16 1994-05-31 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5366736A (en) * 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
AU5185790A (en) * 1989-02-16 1990-09-05 University Of Georgia Research Foundation, Inc., The Treatment of tibial dyschondroplasia
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
US6025346A (en) * 1990-09-21 2000-02-15 Bone Care International, Inc. 1α-hydroxy vitamin D4 and novel intermediates and analogues
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US5801164A (en) * 1990-09-21 1998-09-01 Bone Care International, Inc. Methods of treating osteoporosis prophylactically or therapeutically
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5763429A (en) * 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US6929797B2 (en) * 1997-02-13 2005-08-16 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
US6087350A (en) * 1997-08-29 2000-07-11 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
AU762481C (en) * 1998-03-27 2004-08-19 Oregon Health Sciences University Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders
WO2001040177A2 (en) 1999-12-02 2001-06-07 Women And Infants Hospital Esters of vitamin d3 and uses thereof
IL153378A0 (en) * 2000-07-18 2003-07-06 Bone Care Internat Inc STABILIZED 1alpha-HYDROXY VITAMIN D
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20080039434A1 (en) 2004-03-01 2008-02-14 Bioxell S. P.A. Treatment of Interstitial Cystitis with Vitamin D Compounds
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
EP1812011A1 (en) 2004-11-12 2007-08-01 Bioxell S.p.a. Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
NZ575355A (en) * 2006-09-14 2012-03-30 Dsm Ip Assets Bv Food supplementation composition containing one or more vitamin d3 compounds and one or more magnesium salts
US20110207952A1 (en) * 2010-02-22 2011-08-25 Rafael Avila Cholesterol extraction from algae and preparation of vegan vitamin d3

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565924A (en) * 1968-07-01 1971-02-23 Wisconsin Alumni Res Found 25-hydroxycholfcalciferol
US3702810A (en) * 1971-03-02 1972-11-14 Wisconsin Alumni Res Found Photochemical method for preparing 25-hydroxytachysterol3

Also Published As

Publication number Publication date
JPS4862750A (da) 1973-09-01
CH579042A5 (da) 1976-08-31
FR2162113B1 (da) 1975-10-31
DK138419C (da) 1979-02-12
CH574455A5 (da) 1976-04-15
GB1359407A (en) 1974-07-10
CA966828A (en) 1975-04-29
US3741996A (en) 1973-06-26
DE2259661C3 (de) 1975-12-18
DE2259661A1 (de) 1973-06-07
NL159093B (nl) 1979-01-15
FR2162113A1 (da) 1973-07-13
JPS5654315B2 (da) 1981-12-24
DE2259661B2 (de) 1975-05-15
NL7216324A (da) 1973-06-05

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