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DK1094816T3 - Biphenylsulfonamider som dobbelte angiotensin-endothelin-receptorantagonister - Google Patents

Biphenylsulfonamider som dobbelte angiotensin-endothelin-receptorantagonister

Info

Publication number
DK1094816T3
DK1094816T3 DK99935406T DK99935406T DK1094816T3 DK 1094816 T3 DK1094816 T3 DK 1094816T3 DK 99935406 T DK99935406 T DK 99935406T DK 99935406 T DK99935406 T DK 99935406T DK 1094816 T3 DK1094816 T3 DK 1094816T3
Authority
DK
Denmark
Prior art keywords
receptor antagonists
endothelin receptor
biphenylsulfonamides
dual angiotensin
compounds
Prior art date
Application number
DK99935406T
Other languages
English (en)
Inventor
Natesan Murugesan
John E Tellew
John E Macor
Zhengxiang Gu
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK1094816T3 publication Critical patent/DK1094816T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/12—Antidiarrhoeals
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C07D261/16—Benzene-sulfonamido isoxazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Emergency Medicine (AREA)
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  • Ophthalmology & Optometry (AREA)
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DK99935406T 1998-07-06 1999-07-01 Biphenylsulfonamider som dobbelte angiotensin-endothelin-receptorantagonister DK1094816T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9184798P 1998-07-06 1998-07-06
PCT/US1999/015063 WO2000001389A1 (en) 1998-07-06 1999-07-01 Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists

Publications (1)

Publication Number Publication Date
DK1094816T3 true DK1094816T3 (da) 2009-04-06

Family

ID=22229932

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99935406T DK1094816T3 (da) 1998-07-06 1999-07-01 Biphenylsulfonamider som dobbelte angiotensin-endothelin-receptorantagonister

Country Status (29)

Country Link
EP (2) EP2002837A1 (da)
JP (2) JP2002519380A (da)
KR (1) KR20010083092A (da)
CN (1) CN1149196C (da)
AT (1) ATE416772T1 (da)
AU (1) AU767456B2 (da)
BG (1) BG65404B1 (da)
BR (1) BR9911621A (da)
CA (1) CA2336714A1 (da)
CZ (1) CZ200172A3 (da)
DE (1) DE69940063D1 (da)
DK (1) DK1094816T3 (da)
EE (1) EE200100006A (da)
ES (1) ES2318899T3 (da)
GE (1) GEP20033114B (da)
HU (1) HUP0104634A3 (da)
ID (1) ID26984A (da)
IL (1) IL140622A0 (da)
LT (2) LT4854B (da)
LV (1) LV12639B (da)
NO (1) NO20010062L (da)
NZ (1) NZ508118A (da)
PL (2) PL201048B1 (da)
PT (1) PT1094816E (da)
RU (1) RU2001103044A (da)
SK (1) SK18822000A3 (da)
TR (1) TR200100149T2 (da)
WO (1) WO2000001389A1 (da)
ZA (1) ZA200006772B (da)

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CA2336714A1 (en) 2000-01-13
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