[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DK0974356T3 - Tabletter omfattende en kombination af metformin og glibenclamid - Google Patents

Tabletter omfattende en kombination af metformin og glibenclamid

Info

Publication number
DK0974356T3
DK0974356T3 DK98401781T DK98401781T DK0974356T3 DK 0974356 T3 DK0974356 T3 DK 0974356T3 DK 98401781 T DK98401781 T DK 98401781T DK 98401781 T DK98401781 T DK 98401781T DK 0974356 T3 DK0974356 T3 DK 0974356T3
Authority
DK
Denmark
Prior art keywords
glibenclamide
metformin
tablets
combination
Prior art date
Application number
DK98401781T
Other languages
English (en)
Inventor
Yves Bonhomme
Geoffrey Nicholson
Original Assignee
Merck Sante Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0974356(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sante Sas filed Critical Merck Sante Sas
Application granted granted Critical
Publication of DK0974356T3 publication Critical patent/DK0974356T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98401781T 1998-07-15 1998-07-15 Tabletter omfattende en kombination af metformin og glibenclamid DK0974356T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98401781A EP0974356B1 (en) 1998-07-15 1998-07-15 Tablets comprising a combination of metformin and glibenclamide

Publications (1)

Publication Number Publication Date
DK0974356T3 true DK0974356T3 (da) 2003-10-27

Family

ID=8235441

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98401781T DK0974356T3 (da) 1998-07-15 1998-07-15 Tabletter omfattende en kombination af metformin og glibenclamid

Country Status (27)

Country Link
US (2) US6303146B1 (da)
EP (4) EP0974356B1 (da)
JP (2) JP2002520371A (da)
KR (2) KR100478347B1 (da)
CN (2) CN1486698A (da)
AP (1) AP1450A (da)
AR (2) AR013052A1 (da)
AT (1) ATE250418T1 (da)
AU (2) AU753604B2 (da)
BR (1) BR9906600A (da)
CA (1) CA2303537C (da)
DE (1) DE69818444T2 (da)
DK (1) DK0974356T3 (da)
DZ (1) DZ2846A1 (da)
ES (1) ES2206868T3 (da)
ID (1) ID25784A (da)
MA (1) MA24930A1 (da)
MY (1) MY129552A (da)
NZ (1) NZ503248A (da)
OA (1) OA11400A (da)
PT (1) PT974356E (da)
RU (2) RU2226396C2 (da)
SI (1) SI0974356T1 (da)
TW (2) TWI245632B (da)
UY (1) UY25611A1 (da)
WO (1) WO2000003742A2 (da)
ZA (1) ZA200001159B (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040102486A1 (en) * 1998-11-12 2004-05-27 Smithkline Beecham Corporation Novel method of treatment
US20040081697A1 (en) * 1998-11-12 2004-04-29 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
ATE390140T1 (de) 1999-11-03 2008-04-15 Bristol Myers Squibb Co Arzneimittel, umfassend eine kombination aus metformin und glibenclamide
US6586438B2 (en) * 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
US20010036479A1 (en) 2000-01-14 2001-11-01 Gillian Cave Glyburide composition
FR2816840B1 (fr) 2000-11-17 2004-04-09 Flamel Tech Sa Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
FR2816841B1 (fr) * 2000-11-22 2004-02-06 Lipha Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
CA2725833A1 (en) * 2001-01-12 2002-07-18 Sun Pharmaceutical Industries Limited Spaced drug delivery system
FR2825023B1 (fr) * 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
US20050271737A1 (en) * 2001-06-07 2005-12-08 Chinea Vanessa I Application of a bioactive agent to a substrate
US8206753B2 (en) * 2001-06-20 2012-06-26 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
ES2295369T3 (es) * 2001-07-30 2008-04-16 Mitsubishi Pharma Corporation Farmacos para mejorar la hiperglucemia postcibal.
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
ITFI20010230A1 (it) * 2001-11-29 2003-05-29 Menarini Int Operations Lu Sa Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
US7183321B2 (en) * 2001-12-17 2007-02-27 Bristol-Myers Squibb Company Antidiabetic formulation and method
DK1482919T3 (da) * 2002-01-25 2007-07-30 Silanes Sa De Cv Lab Farmaceutisk sammensætning til blodsukkerkontrol hos patienter med type 2 diabetes
WO2003072089A1 (en) * 2002-02-21 2003-09-04 Biovail Laboratories Inc. Controlled release dosage forms
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
US20030219482A1 (en) * 2002-03-21 2003-11-27 Chaudhari Sunil Sudhakar Multiparticulate compositions for once-a-day administration
CN100553625C (zh) 2002-04-09 2009-10-28 弗拉梅技术公司 活性成分微囊的口服混悬液
EP1492531B3 (fr) 2002-04-09 2012-04-11 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiée d'amoxicilline
US8911781B2 (en) 2002-06-17 2014-12-16 Inventia Healthcare Private Limited Process of manufacture of novel drug delivery system: multilayer tablet composition of thiazolidinedione and biguanides
US7445796B2 (en) * 2002-08-19 2008-11-04 L. Perrigo Company Pharmaceutically active particles of a monomodal particle size distribution and method
EP1562607A1 (en) * 2002-11-15 2005-08-17 Ranbaxy Laboratories, Ltd. Pharmaceutical dosage forms of biguanide-sulfonylurea combinations
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation
US7662366B2 (en) * 2003-04-15 2010-02-16 Chugai Seiyaku Kabushiki Kaisha Method of preventing β cell disruption in pancreatic Langerhans' islets
US20060121108A1 (en) * 2004-12-02 2006-06-08 Prasad C K System and method for producing a directly compressible, high-potency formulation of metformin hydrochloride
CN100341495C (zh) * 2004-12-29 2007-10-10 三九医药股份有限公司 格列本脲固体分散体、口服组合物及其制备方法
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
US8529537B2 (en) * 2005-08-05 2013-09-10 Kimberly-Clark Worldwide, Inc. Absorbent article with enclosures
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
EP2452683A3 (en) 2006-06-26 2012-08-22 Amgen Inc. Methods for treating atherosclerosis
WO2008062273A2 (en) * 2006-11-20 2008-05-29 Cadila Pharmaceuticals Limited Solid oral dosage form having antidiabetic drug combination
AR067557A1 (es) 2007-07-19 2009-10-14 Takeda Pharmaceutical Preparacion solida y metodo de preparacion
EP2181190B1 (en) 2007-07-26 2014-01-08 Amgen, Inc Modified lecithin-cholesterol acyltransferase enzymes
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
WO2011135106A1 (es) * 2010-04-26 2011-11-03 Smart Pharma Solutions, S.L Granulado altamente dispersable para la preparación de formulaciones de sustancias activas de altas dosis y procedimiento de obtención del mismo
RU2451506C1 (ru) 2011-06-02 2012-05-27 Сергей Юрьевич Лешков Комбинация для лечения сахарного диабета и его осложнений
CA2858572C (en) 2011-12-08 2023-01-17 Amgen Inc. Human lcat antigen binding proteins and their use in therapy
CN104127424A (zh) * 2014-07-30 2014-11-05 沈阳药科大学 格列本脲衍生物及其制备方法和应用
CN105030793A (zh) * 2015-08-25 2015-11-11 瑞阳制药有限公司 二甲双胍格列本脲胶囊及其制备方法
WO2019070109A1 (es) * 2017-10-03 2019-04-11 Infinite Clinical Research International, S.A. De C.V. Triconjugado para el tratamiento de diabetes mellitus
KR102484756B1 (ko) * 2020-11-13 2023-01-06 한국생산기술연구원 용해성 증대 및 취급용이성을 갖는 파우더 배지의 과립화 방법
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE362704C (de) * 1921-08-09 1922-11-02 Naamlooze Vennootschap Interna Vorrichtung zum Senken einer Last, insbesondere eines Rettungsbootes
US3174901A (en) 1963-01-31 1965-03-23 Jan Marcel Didier Aron Samuel Process for the oral treatment of diabetes
US4060634A (en) * 1973-09-26 1977-11-29 Boehringer Mannheim G.M.B.H. Rapidly resorbable glibenclamide
DE2348334C2 (de) 1973-09-26 1982-11-11 Boehringer Mannheim Gmbh, 6800 Mannheim Neue Zubereitungsform des N-4-[2-(5-Chlor-2-methoxybenzamido)äthyl]- phenyl-sulfonyl-N'-cyclohexylharnstoffs
US4916163A (en) 1985-06-04 1990-04-10 The Upjohn Company Spray-dried lactose formulation of micronized glyburide
DE3833439A1 (de) 1988-10-01 1991-09-12 Hoechst Ag Verfahren zur mikronisierung von glibenclamid
DK36392D0 (da) 1992-03-19 1992-03-19 Novo Nordisk As Anvendelse af kemisk forbindelse
DE4323636A1 (de) 1993-07-15 1995-01-19 Hoechst Ag Arzneistoffzubereitungen aus umhüllten, schwerstwasserlöslichen Arzneistoffen für Inhalationsarzneiformen und Verfahren zu ihrer Herstellung
TWI238064B (en) 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
IT1276130B1 (it) * 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
NZ501260A (en) 1997-06-18 2002-09-27 Smithkline Beecham P Treatment of diabetes with thiazolidinedione and metformin
US6544564B1 (en) * 2001-11-27 2003-04-08 Michael Donald Farley Cytotoxic pharmaceutical composition

Also Published As

Publication number Publication date
CN1486698A (zh) 2004-04-07
EP0974356B1 (en) 2003-09-24
EP2269613A2 (en) 2011-01-05
NZ503248A (en) 2002-09-27
DE69818444D1 (de) 2003-10-30
TW200303208A (en) 2003-09-01
CA2303537C (en) 2005-12-06
AP1450A (en) 2005-07-25
EP1011684A2 (en) 2000-06-28
RU2003126257A (ru) 2005-02-27
BR9906600A (pt) 2000-07-18
JP2003292443A (ja) 2003-10-15
SI0974356T1 (en) 2003-12-31
RU2226396C2 (ru) 2004-04-10
EP1435240A2 (en) 2004-07-07
EP0974356A1 (en) 2000-01-26
ES2206868T3 (es) 2004-05-16
TWI245632B (en) 2005-12-21
US6303146B1 (en) 2001-10-16
ZA200001159B (en) 2001-05-31
DZ2846A1 (fr) 2003-12-01
ID25784A (id) 2000-11-02
CN1146427C (zh) 2004-04-21
KR100478347B1 (ko) 2005-03-23
DE69818444T2 (de) 2004-05-06
OA11400A (en) 2004-04-08
AP2000001757A0 (en) 2000-03-31
KR20040053177A (ko) 2004-06-23
CA2303537A1 (en) 2000-01-27
PT974356E (pt) 2004-02-27
WO2000003742A3 (en) 2000-04-20
KR20010030603A (ko) 2001-04-16
MA24930A1 (fr) 2000-04-01
AR013052A1 (es) 2000-11-22
EP1435240A3 (en) 2009-08-12
RU2286788C2 (ru) 2006-11-10
AU753604B2 (en) 2002-10-24
AU2003261560A1 (en) 2005-05-26
MY129552A (en) 2007-04-30
JP2002520371A (ja) 2002-07-09
AR065970A2 (es) 2009-07-15
UY25611A1 (es) 2000-08-21
ATE250418T1 (de) 2003-10-15
CN1275082A (zh) 2000-11-29
USRE38629E1 (en) 2004-10-19
EP2269613A3 (en) 2012-10-17
WO2000003742A2 (en) 2000-01-27
AU5417999A (en) 2000-02-07
TW555560B (en) 2003-10-01

Similar Documents

Publication Publication Date Title
DK0974356T3 (da) Tabletter omfattende en kombination af metformin og glibenclamid
DK0948456T3 (da) Fremgangsmåde til fremstilling og anvendelse af en nikkelkatalysator
NO991151D0 (no) Forbindelse og anvendelse derav
DK1231918T3 (da) Hidtil ukendt præparat baseret på en thiazolidindion og metformin og anvendelse deraf
DK1130965T3 (da) Kombinationer af herbicider og modgifte
NO2008003I1 (no) Rosiglitazone maleate og metformin hydroklorid
NO972983L (no) Sulfonamider og deres anvendelse
DK1340600T3 (da) Barberapparat
NO20001914D0 (no) <alfa>-Aryl-N-alkylnitroner og farmasøytiske blandinger som inneholder slike
ID26829A (id) Turunan-turunan sulfonamida
DK1068413T3 (da) Anvendelse af en plade, særligt en vakuumtildannet plade
CY2010001I2 (el) Ετεροκινητο βενζαμιδιο
PT1047300E (pt) Misturas fungicidas a base de compostos amida e de azois
EE200100018A (et) Propoksilaati sisaldavad kütusesegud
DK1022950T3 (da) Stabiliserede blandinger af en iodopropargylforbindelse og en formaldehyddonor
NO20003601D0 (no) Nye naftyl-substituerte og anilid-substituerte sulfonamider
NO995513D0 (no) N-triazolyl-2-indolkarboksamider og deres anvendelse som CCK-A agonister
DE69928050D1 (de) Taktregenerator
NO20000682D0 (no) Pakning og dispenser
NO20013085D0 (no) Fosfororganiske forbindelser og deres anvendelse
DE59912829D1 (de) Cyclophosphamid filmtabletten
DK1137645T3 (da) Alfa-methylbenzylholdige thiourinstofinhibitorer af herpesvira indeholdende en phenylendiamingruppe
NO994504D0 (no) Anti-konvulsive isokinolyl-benzamid-derivater
PL361189A1 (en) Antidiabetic compositions containing a biguanide and a sulfonamide
DK60493D0 (da) Kemiske forbindelser, deres fremstilling og anvendelse