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IT1276130B1 - Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo - Google Patents

Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo

Info

Publication number
IT1276130B1
IT1276130B1 IT95MI002337A ITMI952337A IT1276130B1 IT 1276130 B1 IT1276130 B1 IT 1276130B1 IT 95MI002337 A IT95MI002337 A IT 95MI002337A IT MI952337 A ITMI952337 A IT MI952337A IT 1276130 B1 IT1276130 B1 IT 1276130B1
Authority
IT
Italy
Prior art keywords
glibenclamide
metformin
diabetes mellitus
association
contain
Prior art date
Application number
IT95MI002337A
Other languages
English (en)
Inventor
Giulio Barelli
Regis Massimo De
Original Assignee
Gentili Ist Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11372517&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1276130(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gentili Ist Spa filed Critical Gentili Ist Spa
Priority to IT95MI002337A priority Critical patent/IT1276130B1/it
Publication of ITMI952337A0 publication Critical patent/ITMI952337A0/it
Priority to DE0869796T priority patent/DE869796T1/de
Priority to US09/610,548 priority patent/USRE37330E1/en
Priority to DE69627883T priority patent/DE69627883T2/de
Priority to PT96938124T priority patent/PT869796E/pt
Priority to AT96938124T priority patent/ATE238802T1/de
Priority to BR9611448A priority patent/BR9611448A/pt
Priority to US09/029,371 priority patent/US5922769A/en
Priority to CA002237571A priority patent/CA2237571C/en
Priority to DK96938124T priority patent/DK0869796T3/da
Priority to AU75668/96A priority patent/AU7566896A/en
Priority to PCT/EP1996/004860 priority patent/WO1997017975A1/en
Priority to EP96938124A priority patent/EP0869796B1/en
Priority to ES96938124T priority patent/ES2150889T3/es
Publication of ITMI952337A1 publication Critical patent/ITMI952337A1/it
Publication of IT1276130B1 publication Critical patent/IT1276130B1/it
Application granted granted Critical
Priority to HK98112887A priority patent/HK1011525A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT95MI002337A 1995-11-14 1995-11-14 Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo IT1276130B1 (it)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IT95MI002337A IT1276130B1 (it) 1995-11-14 1995-11-14 Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
ES96938124T ES2150889T3 (es) 1995-11-14 1996-11-07 Combinacion de glibenclamida-metformina para el tratamiento de la diabetes mellitus tipo ii.
US09/029,371 US5922769A (en) 1995-11-14 1996-11-07 Glibenclamide-metformin combination for the treatment of diabetes mellitus of type II
AU75668/96A AU7566896A (en) 1995-11-14 1996-11-07 A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii
DE69627883T DE69627883T2 (de) 1995-11-14 1996-11-07 Zusammensetzung von glibenclamid und metformine zur behandlung von diabetes mellitis typ ii
PT96938124T PT869796E (pt) 1995-11-14 1996-11-07 Associacao de glibenclamida - metformina para o tratamento da diabetes mellitus de tipo ii
AT96938124T ATE238802T1 (de) 1995-11-14 1996-11-07 Zusammensetzung von glibenclamid und metformine zur behandlung von diabetes mellitis typ ii
BR9611448A BR9611448A (pt) 1995-11-14 1996-11-07 Combinação de glibenclamida-metformina para o tratamento de diabetes melito do tipo ii
DE0869796T DE869796T1 (de) 1995-11-14 1996-11-07 Zusammensetzung von glibenclamid und metformine zur behandlung von diabetes mellitis typ ii
CA002237571A CA2237571C (en) 1995-11-14 1996-11-07 A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii
DK96938124T DK0869796T3 (da) 1995-11-14 1996-11-07 Glibenclamid-metformin-kombination til behandling af diabetes mellitus type II
US09/610,548 USRE37330E1 (en) 1995-11-14 1996-11-07 Glibenclamide-metformin combination for the treatment of diabetes mellitus of type II
PCT/EP1996/004860 WO1997017975A1 (en) 1995-11-14 1996-11-07 A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii
EP96938124A EP0869796B1 (en) 1995-11-14 1996-11-07 A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii
HK98112887A HK1011525A1 (en) 1995-11-14 1998-12-07 A glibenclamide-metformin combination for the treatment of diabetes mellitus of type ii

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI002337A IT1276130B1 (it) 1995-11-14 1995-11-14 Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo

Publications (3)

Publication Number Publication Date
ITMI952337A0 ITMI952337A0 (it) 1995-11-14
ITMI952337A1 ITMI952337A1 (it) 1997-05-14
IT1276130B1 true IT1276130B1 (it) 1997-10-27

Family

ID=11372517

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95MI002337A IT1276130B1 (it) 1995-11-14 1995-11-14 Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo

Country Status (12)

Country Link
US (2) USRE37330E1 (it)
EP (1) EP0869796B1 (it)
AT (1) ATE238802T1 (it)
AU (1) AU7566896A (it)
BR (1) BR9611448A (it)
DE (2) DE869796T1 (it)
DK (1) DK0869796T3 (it)
ES (1) ES2150889T3 (it)
HK (1) HK1011525A1 (it)
IT (1) IT1276130B1 (it)
PT (1) PT869796E (it)
WO (1) WO1997017975A1 (it)

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US6291495B1 (en) 1997-02-24 2001-09-18 Robert B. Rieveley Method and composition for the treatment of diabetes
DE69822505T2 (de) * 1997-12-08 2005-01-20 Bristol-Myers Squibb Co. Neue metformin-salze und verfahren
US6099859A (en) 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
HRP990080B1 (en) * 1999-03-12 2003-04-30 Vladimir Leko Plant mixture and a medical preparation for the treatment of diabetes mellitus, type ii, obtained therefrom
EP0974356B1 (en) * 1998-07-15 2003-09-24 Merck Sante Tablets comprising a combination of metformin and glibenclamide
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
AU753933B2 (en) * 1998-09-18 2002-10-31 The, Yong Telephonic transaction system
US6958324B2 (en) * 1998-12-02 2005-10-25 Inotek Pharmaceuticals Corporation Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease
US7056539B2 (en) 1999-03-12 2006-06-06 Vladimir Leko Process and product extracted from herbal composition useful in controlling diabetes mellitus type II
JP2003520759A (ja) * 1999-08-31 2003-07-08 アンドルックス ファーマスーティカルズ インコーポレーテッド 単位核を有する徐放性錠剤
IL149139A0 (en) * 1999-11-03 2002-11-10 Bristol Myers Squibb Co Pharmaceutical compositions containing metformin and glyburide
US6586438B2 (en) 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
US20010036479A1 (en) * 2000-01-14 2001-11-01 Gillian Cave Glyburide composition
WO2001052860A2 (en) * 2000-01-24 2001-07-26 Inotek Corporation Method and composition for modulating an immune response
ES2392705T3 (es) * 2000-10-02 2012-12-13 Usv Ltd. Composiciones farmacéuticas de liberación sostenida que contienen metformina y método para su producción
US6866866B1 (en) * 2000-11-03 2005-03-15 Andrx Labs, Llc Controlled release metformin compositions
US20060034922A1 (en) * 2000-11-03 2006-02-16 Andrx Labs, Llc Controlled release metformin compositions
FR2816840B1 (fr) * 2000-11-17 2004-04-09 Flamel Tech Sa Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
FR2816841B1 (fr) * 2000-11-22 2004-02-06 Lipha Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
ATE508738T1 (de) 2001-01-12 2011-05-15 Sun Pharma Advanced Res Co Ltd System zur beabstandeten abgabe von arzneimitteln
DK1377276T3 (da) * 2001-04-10 2012-01-02 Sun Pharma Advanced Res Co Ltd Beregning af puls-frigivelsessammensætning
FR2825023B1 (fr) * 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
DK1420774T3 (da) * 2001-08-31 2008-11-24 Australian Biomedical Company Fremstilling og diabetisk anvendelse af gibberelliner
KR20040044992A (ko) * 2001-09-28 2004-05-31 썬 파마슈티컬 인더스트리스 리미티드 당뇨병 치료용 투여형태
FR2830447B1 (fr) * 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
ITFI20010230A1 (it) * 2001-11-29 2003-05-29 Menarini Int Operations Lu Sa Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
US7183321B2 (en) * 2001-12-17 2007-02-27 Bristol-Myers Squibb Company Antidiabetic formulation and method
ATE361065T1 (de) 2002-01-25 2007-05-15 Silanes Sa De Cv Lab Pharmazeutische zusammensetzung zur kontrolle des blutzuckers bei patienten mit typ 2 diabetes
US6682759B2 (en) 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
WO2003068209A1 (en) * 2002-02-14 2003-08-21 Sonus Pharmaceuticals, Inc. Metformin salts of lipophilic acids
US7811593B2 (en) * 2002-03-25 2010-10-12 Jian Luo Pharmaceutical composition with combined active agents and methods for using the same
ATE407674T1 (de) * 2002-04-09 2008-09-15 Flamel Tech Sa Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
EP1492511B3 (fr) 2002-04-09 2012-05-02 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
US8911781B2 (en) 2002-06-17 2014-12-16 Inventia Healthcare Private Limited Process of manufacture of novel drug delivery system: multilayer tablet composition of thiazolidinedione and biguanides
EP1549296A4 (en) 2002-08-02 2006-08-09 Penwest Pharmaceuticals Co METFORMIN FORMULATIONS WITH DELAYED RELEASE
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation
WO2004108067A2 (en) * 2003-04-03 2004-12-16 Sun Pharmaceutical Industries Limited Programmed drug delivery system
US20050013863A1 (en) * 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
US20060073213A1 (en) * 2004-09-15 2006-04-06 Hotamisligil Gokhan S Reducing ER stress in the treatment of obesity and diabetes
WO2006031931A2 (en) * 2004-09-15 2006-03-23 The President And Fellows Of Harvard College Reducing er stress in the treatment of obesity and diabetes
JOP20180109A1 (ar) * 2005-09-29 2019-01-30 Novartis Ag تركيبة جديدة
FR2896157B1 (fr) 2006-01-13 2008-09-12 Merck Sante Soc Par Actions Si Combinaison de derives de triazine et d'agents de stimulation de secretion d'insuline.
WO2008062273A2 (en) * 2006-11-20 2008-05-29 Cadila Pharmaceuticals Limited Solid oral dosage form having antidiabetic drug combination
CN105030793A (zh) * 2015-08-25 2015-11-11 瑞阳制药有限公司 二甲双胍格列本脲胶囊及其制备方法

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DE2325581A1 (de) 1973-05-19 1974-12-05 Hoechst Ag Partiell hydrierte 1h-indeno eckige klammer auf 1,2-b eckige klammer zu -pyridin-derivate und verfahren zu ihrer herstellung
JPS5936885B2 (ja) 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
DE2720926C2 (de) 1977-05-10 1983-02-17 Hoechst Ag, 6000 Frankfurt Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung
GB8613689D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
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JP3338119B2 (ja) 1993-04-14 2002-10-28 呉羽化学工業株式会社 抗糖尿病剤

Also Published As

Publication number Publication date
HK1011525A1 (en) 1999-07-16
ES2150889T1 (es) 2000-12-16
AU7566896A (en) 1997-06-05
WO1997017975A1 (en) 1997-05-22
BR9611448A (pt) 1999-03-23
ITMI952337A0 (it) 1995-11-14
EP0869796B1 (en) 2003-05-02
PT869796E (pt) 2003-09-30
USRE37330E1 (en) 2001-08-14
ES2150889T3 (es) 2004-01-01
ATE238802T1 (de) 2003-05-15
US5922769A (en) 1999-07-13
DK0869796T3 (da) 2003-08-18
DE69627883D1 (de) 2003-06-05
ITMI952337A1 (it) 1997-05-14
EP0869796A1 (en) 1998-10-14
DE869796T1 (de) 2001-04-19
DE69627883T2 (de) 2004-05-19

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