DK0736009T3 - N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter - Google Patents

N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter

Info

Publication number: DK0736009T3
Authority: DK; Denmark
Prior art keywords: arylpiperidines; arylpiperazines; oxides; antipsychotic drugs; antipsychotic
Prior art date: 1993-12-23

Application number

DK95906100T

Other languages

English (en)

Inventor

Allen B Reitz

Mark E Mcdonnell

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-23

Filing date

1994-12-22

Publication date

2002-10-07

1994-12-22 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

2002-10-07 Application granted granted Critical

2002-10-07 Publication of DK0736009T3 publication Critical patent/DK0736009T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/24—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK95906100T 1993-12-23 1994-12-22 N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter DK0736009T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17338293A	1993-12-23	1993-12-23
PCT/US1994/014850 WO1995017385A1 (en)	1993-12-23	1994-12-22	N-oxides of 4-arylpiperazines and 4-arylpiperidines as antipsychotic drugs

Publications (1)

Publication Number	Publication Date
DK0736009T3 true DK0736009T3 (da)	2002-10-07

Family

ID=22631753

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95906100T DK0736009T3 (da)	1993-12-23	1994-12-22	N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter

Country Status (16)

Country	Link
EP (1)	EP0736009B1 (da)
JP (1)	JPH09507077A (da)
AT (1)	ATE223898T1 (da)
AU (1)	AU687501B2 (da)
CA (1)	CA2179735A1 (da)
DE (1)	DE69431360T2 (da)
DK (1)	DK0736009T3 (da)
ES (1)	ES2183862T3 (da)
IL (1)	IL112099A (da)
MX (1)	MX9500228A (da)
NZ (1)	NZ278261A (da)
PT (1)	PT736009E (da)
RU (1)	RU2123001C1 (da)
SI (1)	SI0736009T1 (da)
WO (1)	WO1995017385A1 (da)
ZA (1)	ZA9410287B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE46117E1 (en)	1999-12-22	2016-08-23	Teva Pharmaceuticals International Gmbh	Modulators of dopamine neurotransmission
MXPA03001276A (es) *	2000-08-11	2003-09-05	Ono Pharmaceutical Co	Derivados de piperidina y farmacos que contienen esos derivados como el ingrediente activo.
ES2278321T3 (es)	2003-06-12	2007-08-01	Btg International Limited	Hidroxilamina ciclica como compuestos psicoactivos.
NZ580856A (en) *	2007-04-12	2011-11-25	Nsab Af Neurosearch Sweden Ab	N-oxide and/or di-n-oxide derivatives of dopamine receptor stabilizers/modulators displaying improved cardiovascular side-effects profiles
US9012476B2 (en)	2011-12-08	2015-04-21	IVAX International GmbH	Hydrobromide salt of pridopidine
WO2013152105A1 (en)	2012-04-04	2013-10-10	IVAX International GmbH	Pharmaceutical compositions for combination therapy
EP3236964A4 (en)	2014-12-22	2018-09-19	Teva Pharmaceuticals International GmbH	L-tartrate salt of pridopidine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE914218A1 (en) *	1991-09-11	1993-03-24	Mcneilab Inc	Novel 4-arylpiperazines and 4-arylpiperidines
FR2697251B1 (fr) *	1992-10-22	1994-12-02	Synthelabo	N-oxydes de dérivés de 1-(4-chlorophényl)-2-[4-[(4-fluorophényl)méthyl] pipéridin-1-yl]éthanol, leur procédé de préparation et leur application en thérapeutique.

1994
- 1994-12-21 IL IL11209994A patent/IL112099A/xx not_active IP Right Cessation
- 1994-12-22 CA CA002179735A patent/CA2179735A1/en not_active Abandoned
- 1994-12-22 NZ NZ278261A patent/NZ278261A/en unknown
- 1994-12-22 SI SI9430427T patent/SI0736009T1/xx unknown
- 1994-12-22 ZA ZA9410287A patent/ZA9410287B/xx unknown
- 1994-12-22 DK DK95906100T patent/DK0736009T3/da active
- 1994-12-22 AU AU14446/95A patent/AU687501B2/en not_active Ceased
- 1994-12-22 EP EP95906100A patent/EP0736009B1/en not_active Expired - Lifetime
- 1994-12-22 ES ES95906100T patent/ES2183862T3/es not_active Expired - Lifetime
- 1994-12-22 WO PCT/US1994/014850 patent/WO1995017385A1/en active IP Right Grant
- 1994-12-22 AT AT95906100T patent/ATE223898T1/de not_active IP Right Cessation
- 1994-12-22 RU RU96115155A patent/RU2123001C1/ru not_active IP Right Cessation
- 1994-12-22 JP JP7517623A patent/JPH09507077A/ja not_active Ceased
- 1994-12-22 PT PT95906100T patent/PT736009E/pt unknown
- 1994-12-22 DE DE69431360T patent/DE69431360T2/de not_active Expired - Fee Related
1995
- 1995-01-02 MX MX9500228A patent/MX9500228A/es not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0736009A1 (en)	1996-10-09
AU1444695A (en)	1995-07-10
DE69431360D1 (de)	2002-10-17
MX9500228A (es)	1997-02-28
SI0736009T1 (en)	2003-04-30
JPH09507077A (ja)	1997-07-15
ZA9410287B (en)	1996-06-24
AU687501B2 (en)	1998-02-26
PT736009E (pt)	2003-01-31
CA2179735A1 (en)	1995-06-29
ATE223898T1 (de)	2002-09-15
NZ278261A (en)	1998-08-26
RU2123001C1 (ru)	1998-12-10
WO1995017385A1 (en)	1995-06-29
EP0736009B1 (en)	2002-09-11
IL112099A0 (en)	1995-03-15
DE69431360T2 (de)	2003-01-23
IL112099A (en)	1999-07-14
ES2183862T3 (es)	2003-04-01

Publication	Publication Date	Title
DK0563345T3 (da)	2002-10-14	Nye 4-arylpiperaziner og 4-arylpiperidiner
DK0559019T3 (da)	2000-03-27	14-beta-hydroxy-10-deacetyl-baccatin III og derivater deraf som antitumormidler
PT789578E (pt)	2003-10-31	Inibidores da protease multicatalitica
AU6787390A (en)	1991-06-13	Nitrogen-containing spirocycles
DE59510421D1 (de)	2002-11-21	Substituierte Pyridylpyrazole
DK1097173T3 (da)	2008-09-01	Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler
ATE167670T1 (de)	1998-07-15	N-alkylthiopolyaminderivate als radioprotektive mittel
NO952205L (no)	1995-06-02	Heterocykliske karbamater, fremgangsmåte for fremstilling derav og medikamenter
DK0638068T3 (da)	1999-11-22	Fremgangsmåde til fremstilling af (S)-3-amino-1-substitueret-pyrrolidiner
DK0736009T3 (da)	2002-10-07	N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter
SE8500107D0 (sv)	1985-01-10	Neue 8alfa-acylaminoergoline
FI955118A0 (fi)	1995-10-27	Herbisidiset substituoidut 1-fenyyli- tai 1-pyridinyyli-bentsotriatsolit
ES2104174T3 (es)	1997-10-01	Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.
TR199701298T1 (xx)	1998-02-21	Tetralinler.
TR200001122T2 (tr)	2000-08-21	Farmasötikler olarak bifenil türevleri.
ATE339204T1 (de)	2006-10-15	Freisetzungsregulierende zubereitungen
CO4770971A1 (es)	1999-04-30	Compuestos quimicos
UY24326A1 (es)	2000-12-29	Nuevas piperidinas.
GR1001368B (el)	1993-10-29	Φαρμακευτικοί φορείς.
DK0779075T3 (da)	2002-02-18	Anvendelse af 3-alpha-hydroxy-5-alpha-androsta-16-en som lægemidler