[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DK0621775T3 - Peptide drug-containing pellets, their preparation and use. - Google Patents

Peptide drug-containing pellets, their preparation and use.

Info

Publication number
DK0621775T3
DK0621775T3 DK93902032.7T DK93902032T DK0621775T3 DK 0621775 T3 DK0621775 T3 DK 0621775T3 DK 93902032 T DK93902032 T DK 93902032T DK 0621775 T3 DK0621775 T3 DK 0621775T3
Authority
DK
Denmark
Prior art keywords
preparation
peptide drug
containing pellets
pellets
drug
Prior art date
Application number
DK93902032.7T
Other languages
Danish (da)
Inventor
Juergen Freidenreich
Juergen Werry
Ursula Schick
Jens-Christian Wunderlich
Original Assignee
Alfatec Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4201179A external-priority patent/DE4201179A1/en
Application filed by Alfatec Pharma Gmbh filed Critical Alfatec Pharma Gmbh
Application granted granted Critical
Publication of DK0621775T3 publication Critical patent/DK0621775T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Described are pellets containing peptide drugs incorporated in a matrix consisting of gelatin or fractionated gelatin and plasticizers, the pellets having a semi-solid to gel-like consistency. Such drug forms exhibit, after application, bioadhesive properties and, by virtue of the matrix materials specified, allow or enhance the resorption of the peptide drug by the body.
DK93902032.7T 1992-01-17 1993-01-18 Peptide drug-containing pellets, their preparation and use. DK0621775T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4201179A DE4201179A1 (en) 1992-01-17 1992-01-17 Granulates or pellets comprising dispersion of active agent in hydrophilic macromolecules - are e.g. for treatment of depression, hypertension, rheumatism, etc.
US87686592A 1992-04-30 1992-04-30

Publications (1)

Publication Number Publication Date
DK0621775T3 true DK0621775T3 (en) 1997-10-06

Family

ID=25911046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93902032.7T DK0621775T3 (en) 1992-01-17 1993-01-18 Peptide drug-containing pellets, their preparation and use.

Country Status (8)

Country Link
EP (1) EP0621775B1 (en)
AT (1) ATE156350T1 (en)
AU (1) AU3343093A (en)
DE (1) DE59307073D1 (en)
DK (1) DK0621775T3 (en)
ES (1) ES2108258T3 (en)
GR (1) GR3024529T3 (en)
WO (1) WO1993013753A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE142484T1 (en) 1992-01-17 1996-09-15 Alfatec Pharma Gmbh SOLID BODY CONTAINING ACTIVE INGREDIENTS WITH A FRAMEWORK OF HYDROPHILIC MACROMOLECLES AND METHOD FOR THE PRODUCTION THEREOF
AU1677095A (en) * 1994-01-11 1995-08-01 Alkermes Controlled Therapeutics, Inc. Oral dosage form of desmopressin (ddavp)
CA2164262A1 (en) * 1995-12-01 1997-06-02 Charles J. Doillon Biostable porous material comprising composite biopolymers
US5686133A (en) * 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals
JP2000509036A (en) * 1996-04-22 2000-07-18 ピーター・アール・ロスチャイルド Stabilized anti-hepatitis B vaccine tablet
IT1293087B1 (en) * 1997-07-10 1999-02-11 Isi Ist Sierovaccinogeno Ital MICROPARTICLES BASED ON HYBRID POLYMER MATERIALS FOR THE CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE MOLECULES, PROCEDURE FOR THE
JP2001507722A (en) * 1997-11-06 2001-06-12 オーボン コーポレイション Stabilized dry pharmaceutical compositions for drug delivery and methods of preparing the same
DE19821951A1 (en) * 1998-05-15 1999-11-18 Basf Ag Orally administered solid or liquid cyclosporin compositions
DE10332160A1 (en) * 2003-07-15 2005-02-03 Röhm GmbH & Co. KG Multiparticulate dosage form containing mucoadhesively formulated peptide or protein active substances, and a method for producing the dosage form
DE102005054937A1 (en) * 2005-11-17 2007-05-24 Gelita Ag Angiogenesis promoting substrate
DE102005054938A1 (en) * 2005-11-17 2007-05-24 Gelita Ag Shaped body based on a crosslinked, gelatin-containing material, process for their preparation and their use
CA2683415C (en) 2007-04-04 2020-12-08 Sigmoid Pharma Limited An oral pharmaceutical composition
EP2586428B1 (en) 2007-04-26 2023-11-08 Sublimity Therapeutics Limited Manufacture of multiple minicapsules
DK2471518T3 (en) 2009-05-18 2017-12-04 Sigmoid Pharma Ltd COMPOSITION INCLUDING OIL DROPS
IN2012DN00781A (en) 2009-08-12 2015-06-26 Sigmoid Pharma Ltd
PL2538955T3 (en) * 2010-02-25 2016-04-29 Evonik Roehm Gmbh Pharmaceutical or nutraceutical formulation
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319792D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
PL3215127T3 (en) 2014-11-07 2021-05-17 Sublimity Therapeutics Limited Compositions comprising cyclosporin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB887901A (en) * 1960-04-13 1900-01-01
US3312594A (en) * 1963-06-21 1967-04-04 Squibb & Sons Inc Longlasting troche
GB8514090D0 (en) * 1985-06-04 1985-07-10 Sandoz Ltd Organic compounds
DE3486029T2 (en) * 1983-10-14 1993-05-13 Sumitomo Pharma IFN PREPARATION WITH DELAYED DELIVERY FOR PARENTAL ADMINISTRATION.
WO1985005029A1 (en) * 1984-05-09 1985-11-21 Medaphore Inc. Oral insulin and a method of making the same
CA1277601C (en) * 1985-12-27 1990-12-11 Shigeji Sato Method for producing sustained release formulation
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution

Also Published As

Publication number Publication date
AU3343093A (en) 1993-08-03
ATE156350T1 (en) 1997-08-15
WO1993013753A1 (en) 1993-07-22
EP0621775A1 (en) 1994-11-02
DE59307073D1 (en) 1997-09-11
EP0621775B1 (en) 1997-08-06
ES2108258T3 (en) 1997-12-16
GR3024529T3 (en) 1997-12-31

Similar Documents

Publication Publication Date Title
DK0621775T3 (en) Peptide drug-containing pellets, their preparation and use.
BR9406363A (en) Pharmaceutical composition process for the preparation of the same use and process for the treatment of diseases related to gastric acid
HUP0000737A2 (en) Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid
DE69326063D1 (en) PHARMACEUTICAL AND OTHER PHARMACEUTICAL FORMS
DK476089A (en) THERAPEUTIC ACTIVE RELATIONS AND THEIR PREPARATION
DE3875108D1 (en) PHYSIOLOGICALLY ACTIVE POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION.
RU94032150A (en) Medicinal agent exhibiting delayed release of active-acting substance
DE3674570D1 (en) N, N-DIMETHYL-1- (1- (4-CHLOROPHENYL) -CYCLOBUTYL) -3-METHYLBUTYLAMINE HYDROCHLORIDE, MONOHYDRATE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THESE.
AR002754A1 (en) PHARMACEUTICAL COMPOSITION COMPRISING MICRO-ENCAPSULATED VIABLE LACTOBACILLUS BACTERIA, AND USE OF THE COMPOSITION TO PREPARE A MEDICINAL PRODUCT
SE8504945D0 (en) PHARMACEUTICAL COMPOSITIONS CONTAINING ANTHRACYCLINE GLYCOSIDES
IT1232677B (en) PHARMACEUTICAL COMPOSITION CONTAINING RANITIDINE
ATE75945T1 (en) PHARMACEUTICAL PREPARATION FOR TREATMENT OF DIABETES MELLITUS.
DE68909772D1 (en) Diclofenac sodium drug preparation with extended release of active ingredient.
MX9202804A (en) PHARMACEUTICAL AND THERAPEUTIC COMPOSITION THAT INCLUDES A NEW MOLECULA OF INTRACELLULAR ADHESION.
NO900276D0 (en) NEW BENZOPYRANE DERIVATIVES, THEIR PREPARATION AND USE OF PHARMACEUTICAL PREPARATIONS.
DE3880212D1 (en) PHARMACEUTICAL COMPOSITION FOR SKIN ABSORPTION AND SKIN ABSORPTION REINFORCEMENT OF MEDICATIONS.
IT1237410B (en) RANITIDINE HYDROCHLORIDE TABLET AND PROCEDURE TO PRODUCE IT
DK164202C (en) PHARMACEUTICAL PREPARATIONS FOR TOPICAL USE CONTAINING INTERFERON-ALFA AND PROCEDURES FOR THEIR PREPARATION
IT8820073A0 (en) AQUEOUS PHARMACEUTICAL FORMULATIONS OF PIROXICAM AND PROCEDURE FOR THEIR PREPARATION.
DE68902300D1 (en) PHARMACEUTICAL SOLUTION CONTAINING SALBUTAMOL AND CROMOGLYCIN ACID.
GR880100775A (en) Neutrophilics activation element
DK381189D0 (en) N-2,3-BUTADIENYL-TRI- AND TETRAAMINOALKANDER DERIVATIVES AND THEIR USE
DK298389A (en) PHARMACEUTICAL PREPARATION FOR TOPICAL USE INCLUDING AN AMINE-FUNCTIONAL MEDICINE
DK578589A (en) PHARMACEUTICAL PREPARATION CONTAINING LABDANTERPENOID DERIVATIVES AND PYRIMIDO (6.1-A) ISOQUINOLIN-4 UNDERGRATES, ITS PREPARATION AND USE
DE68900926D1 (en) PHARMACEUTICAL PREPARATION CONTAINING ZIDOVUDINE AND INOSIPLEX, OR INGREDIENTS THEREOF, FOR THE TREATMENT OF AIDS-RELATED SYNDROME.