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DK0621775T3 - Peptidlægemiddelholdige pellets, deres fremstilling og anvendelse. - Google Patents

Peptidlægemiddelholdige pellets, deres fremstilling og anvendelse.

Info

Publication number
DK0621775T3
DK0621775T3 DK93902032.7T DK93902032T DK0621775T3 DK 0621775 T3 DK0621775 T3 DK 0621775T3 DK 93902032 T DK93902032 T DK 93902032T DK 0621775 T3 DK0621775 T3 DK 0621775T3
Authority
DK
Denmark
Prior art keywords
preparation
peptide drug
containing pellets
pellets
drug
Prior art date
Application number
DK93902032.7T
Other languages
English (en)
Inventor
Juergen Freidenreich
Juergen Werry
Ursula Schick
Jens-Christian Wunderlich
Original Assignee
Alfatec Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4201179A external-priority patent/DE4201179A1/de
Application filed by Alfatec Pharma Gmbh filed Critical Alfatec Pharma Gmbh
Application granted granted Critical
Publication of DK0621775T3 publication Critical patent/DK0621775T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK93902032.7T 1992-01-17 1993-01-18 Peptidlægemiddelholdige pellets, deres fremstilling og anvendelse. DK0621775T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4201179A DE4201179A1 (de) 1992-01-17 1992-01-17 Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung
US87686592A 1992-04-30 1992-04-30

Publications (1)

Publication Number Publication Date
DK0621775T3 true DK0621775T3 (da) 1997-10-06

Family

ID=25911046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93902032.7T DK0621775T3 (da) 1992-01-17 1993-01-18 Peptidlægemiddelholdige pellets, deres fremstilling og anvendelse.

Country Status (8)

Country Link
EP (1) EP0621775B1 (da)
AT (1) ATE156350T1 (da)
AU (1) AU3343093A (da)
DE (1) DE59307073D1 (da)
DK (1) DK0621775T3 (da)
ES (1) ES2108258T3 (da)
GR (1) GR3024529T3 (da)
WO (1) WO1993013753A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59309678D1 (de) 1992-01-17 1999-08-05 Alfatec Pharma Gmbh Verfahren zur Herstellung von Wirkstoff enthaltenden Pulvern, Granulaten oder Pellets mit einem Gerüst aus hydrophilen Makromolekülen und ihre Verwendung
AU1677095A (en) * 1994-01-11 1995-08-01 Alkermes Controlled Therapeutics, Inc. Oral dosage form of desmopressin (ddavp)
CA2164262A1 (en) * 1995-12-01 1997-06-02 Charles J. Doillon Biostable porous material comprising composite biopolymers
US5686133A (en) * 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals
CN1216471A (zh) * 1996-04-22 1999-05-12 彼得·R·罗斯席尔德 稳定的抗乙型肝炎疫苗片
IT1293087B1 (it) * 1997-07-10 1999-02-11 Isi Ist Sierovaccinogeno Ital Microparticelle a base di materiali polimerici ibridi per il rilascio controllato di molecole biologicamente attive, procedimento per la
AU1307399A (en) * 1997-11-06 1999-05-31 Orbon Corporation Stabilized, dry pharmaceutical compositions for drug delivery and methods of preparing same
DE19821951A1 (de) * 1998-05-15 1999-11-18 Basf Ag Cyclosporin-Zubereitungen
DE10332160A1 (de) * 2003-07-15 2005-02-03 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
DE102005054937A1 (de) * 2005-11-17 2007-05-24 Gelita Ag Angiogenese förderndes Substrat
DE102005054938A1 (de) * 2005-11-17 2007-05-24 Gelita Ag Formkörper auf Basis eines vernetzten, Gelatine enthaltenden Materials, Verfahren zu deren Herstellung sowie deren Verwendung
CN103120653B (zh) 2007-04-04 2015-09-30 希格默伊德药业有限公司 一种口服药物组合物
EP2061587A1 (en) 2007-04-26 2009-05-27 Sigmoid Pharma Limited Manufacture of multiple minicapsules
DK2432455T3 (da) * 2009-05-18 2015-02-16 Sigmoid Pharma Ltd Sammensætning omfattende oliedråber
CA2770570A1 (en) 2009-08-12 2011-02-17 Sigmoid Pharma Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
RU2604861C2 (ru) 2010-02-25 2016-12-10 Эвоник Рем ГмбХ Фармацевтический или нутрицевтический состав
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
GB201319792D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
DK3215127T3 (da) 2014-11-07 2021-02-01 Sublimity Therapeutics Ltd Sammensætninger omfattende cyclosporin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB887901A (da) * 1960-04-13 1900-01-01
US3312594A (en) * 1963-06-21 1967-04-04 Squibb & Sons Inc Longlasting troche
GB8514090D0 (en) * 1985-06-04 1985-07-10 Sandoz Ltd Organic compounds
DE3486029T2 (de) * 1983-10-14 1993-05-13 Sumitomo Pharma Ifn-praeparat mit verzoegerter abgabe fuer parentale verabreichung.
EP0179904A1 (en) * 1984-05-09 1986-05-07 Medaphore Inc. Oral insulin and a method of making the same
ATE87469T1 (de) * 1985-12-27 1993-04-15 Sumitomo Pharma Verfahren zur herstellung einer formulierung mit verzoegerter freisetzung.
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution

Also Published As

Publication number Publication date
WO1993013753A1 (de) 1993-07-22
EP0621775B1 (de) 1997-08-06
ES2108258T3 (es) 1997-12-16
DE59307073D1 (de) 1997-09-11
ATE156350T1 (de) 1997-08-15
GR3024529T3 (en) 1997-12-31
EP0621775A1 (de) 1994-11-02
AU3343093A (en) 1993-08-03

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