DK0612745T3 - Fremgangsmåde til fremstilling af 1,2,3,4,10,14b-hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepin og salte deraf - Google Patents
Fremgangsmåde til fremstilling af 1,2,3,4,10,14b-hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepin og salte derafInfo
- Publication number
- DK0612745T3 DK0612745T3 DK94101043T DK94101043T DK0612745T3 DK 0612745 T3 DK0612745 T3 DK 0612745T3 DK 94101043 T DK94101043 T DK 94101043T DK 94101043 T DK94101043 T DK 94101043T DK 0612745 T3 DK0612745 T3 DK 0612745T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyrazino
- azepine
- hexahydro
- preparation
- dibenzo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4305659A DE4305659A1 (de) | 1993-02-24 | 1993-02-24 | Verfahren zur Herstellung von 1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepin und seiner Salze |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0612745T3 true DK0612745T3 (da) | 1999-08-16 |
Family
ID=6481214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94101043T DK0612745T3 (da) | 1993-02-24 | 1994-01-25 | Fremgangsmåde til fremstilling af 1,2,3,4,10,14b-hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepin og salte deraf |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0612745B1 (da) |
JP (1) | JP3364519B2 (da) |
AT (1) | ATE174335T1 (da) |
DE (2) | DE4305659A1 (da) |
DK (1) | DK0612745T3 (da) |
ES (1) | ES2124802T3 (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102558075A (zh) | 2004-12-03 | 2012-07-11 | 先灵公司 | 作为cb1拮抗剂的取代哌嗪 |
AR059021A1 (es) | 2006-01-18 | 2008-03-05 | Schering Corp | Moduladores de receptores cannabinoides |
BRPI0814806A2 (pt) | 2007-06-28 | 2015-02-03 | Intervet Int Bv | Pirazinas substituídas como antagonistas de cb1 |
CN117777144A (zh) * | 2023-12-26 | 2024-03-29 | 仁和堂药业有限公司 | 一种盐酸米安色林新晶型ⅱ及其制备方法 |
CN117777146A (zh) * | 2023-12-29 | 2024-03-29 | 仁和堂药业有限公司 | 一种盐酸米安色林一水合物新晶型ⅰ及其制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL179906C (nl) * | 1974-02-09 | 1986-12-01 | Akzo Nv | Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten. |
-
1993
- 1993-02-24 DE DE4305659A patent/DE4305659A1/de not_active Withdrawn
-
1994
- 1994-01-25 ES ES94101043T patent/ES2124802T3/es not_active Expired - Lifetime
- 1994-01-25 EP EP94101043A patent/EP0612745B1/de not_active Expired - Lifetime
- 1994-01-25 DE DE59407418T patent/DE59407418D1/de not_active Expired - Lifetime
- 1994-01-25 DK DK94101043T patent/DK0612745T3/da active
- 1994-01-25 AT AT94101043T patent/ATE174335T1/de active
- 1994-02-14 JP JP01745794A patent/JP3364519B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0612745A1 (de) | 1994-08-31 |
ES2124802T3 (es) | 1999-02-16 |
DE59407418D1 (de) | 1999-01-21 |
JPH06312988A (ja) | 1994-11-08 |
JP3364519B2 (ja) | 2003-01-08 |
EP0612745B1 (de) | 1998-12-09 |
ATE174335T1 (de) | 1998-12-15 |
DE4305659A1 (de) | 1994-08-25 |
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