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DE69233323D1 - Pflanzliche mittelkettige thioesterasen - Google Patents

Pflanzliche mittelkettige thioesterasen

Info

Publication number
DE69233323D1
DE69233323D1 DE69233323T DE69233323T DE69233323D1 DE 69233323 D1 DE69233323 D1 DE 69233323D1 DE 69233323 T DE69233323 T DE 69233323T DE 69233323 T DE69233323 T DE 69233323T DE 69233323 D1 DE69233323 D1 DE 69233323D1
Authority
DE
Germany
Prior art keywords
medium chain
vegetable medium
thioesterases
chain thioesterases
plant thioesterases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69233323T
Other languages
English (en)
Other versions
DE69233323T2 (de
Inventor
Alois Voelker
Maelor Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Calgene LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calgene LLC filed Critical Calgene LLC
Publication of DE69233323D1 publication Critical patent/DE69233323D1/de
Application granted granted Critical
Publication of DE69233323T2 publication Critical patent/DE69233323T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings or cooking oils
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6418Fatty acids by hydrolysis of fatty acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fats And Perfumes (AREA)
DE69233323T 1991-05-21 1992-05-21 Pflanzliche mittelkettige thioesterasen Expired - Lifetime DE69233323T2 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US70486191A 1991-05-21 1991-05-21
US704861 1991-05-21
US77309691A 1991-10-07 1991-10-07
US773096 1991-10-07
US78226391A 1991-10-24 1991-10-24
US782263 1991-10-24
US07/824,247 US5512482A (en) 1990-04-26 1992-01-22 Plant thioesterases
US824247 1992-01-22
PCT/US1992/004332 WO1992020236A1 (en) 1991-05-21 1992-05-21 Plant medium-chain thioesterases

Publications (2)

Publication Number Publication Date
DE69233323D1 true DE69233323D1 (de) 2004-04-22
DE69233323T2 DE69233323T2 (de) 2005-02-24

Family

ID=27505488

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69233323T Expired - Lifetime DE69233323T2 (de) 1991-05-21 1992-05-21 Pflanzliche mittelkettige thioesterasen

Country Status (8)

Country Link
US (1) US5512482A (de)
EP (1) EP0557469B1 (de)
JP (1) JP2002238386A (de)
AT (1) ATE262042T1 (de)
CA (1) CA2109580C (de)
DE (1) DE69233323T2 (de)
ES (1) ES2217253T3 (de)
WO (1) WO1992020236A1 (de)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
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US7053267B2 (en) * 1990-03-16 2006-05-30 Calgene Llc Plant seed oils
US6028247A (en) * 1990-04-26 2000-02-22 Voelker; Toni Alois Plant C18:1 preferring thioesterases
US5512482A (en) * 1990-04-26 1996-04-30 Calgene, Inc. Plant thioesterases
US5455167A (en) * 1991-05-21 1995-10-03 Calgene Inc. Medium-chain thioesterases in plants
GB9204583D0 (en) * 1992-03-03 1992-04-15 Unilever Plc Recombinant plant enzyme
US5850022A (en) * 1992-10-30 1998-12-15 Calgene, Inc. Production of myristate in plant cells
US5654495A (en) * 1992-10-30 1997-08-05 Calgene, Inc. Production of myristate in plant cells
CA2169094A1 (en) * 1993-09-03 1995-03-09 Reinhard Topfer Medium chain-specific thioesterases
US6133506A (en) * 1993-09-04 2000-10-17 Max-Planck-Gesellschaft Zur Forerung Der Wissenschaft E.V. Keto-acyl-(ACP) reductase promoter from cuphea lanceolata
WO1995013390A2 (en) * 1993-11-10 1995-05-18 Calgene, Inc. Plant acyl acp thioesterase sequences
US5807893A (en) * 1993-11-18 1998-09-15 Voelker; Toni Alois Plant thioesterases and use for modification of fatty acid composition in plant seed oils
US6093568A (en) * 1994-04-06 2000-07-25 Calgene, Inc. Plant lysophosphatidic acid acyltransferases
US5910630A (en) * 1994-04-06 1999-06-08 Davies; Huw Maelor Plant lysophosphatidic acid acyltransferases
US5563058A (en) * 1994-04-06 1996-10-08 Calgene, Inc. Plant lysophosphatidic acid acyltransferases
ES2128057T3 (es) * 1994-05-10 1999-05-01 Unilever Nv Un procedimiento para preparar una materia grasa solida, una materia grasa solida y un producto untable de grasa plastica que comprende dicha materia grasa solida.
AU706866B2 (en) * 1994-08-31 1999-06-24 E.I. Du Pont De Nemours And Company Nucleotide sequences of canola and soybean palmitoyl-acp thioesterase genes and their use in the regulation of fatty acid content of the oils of soybean and canola plants
JP3256952B2 (ja) 1994-11-09 2002-02-18 日本製紙株式会社 植物への遺伝子導入用ベクター、並びにこれを用いた遺伝子導入植物の作成方法及び植物への遣伝子多重導入方法
EP0830453A2 (de) * 1995-05-15 1998-03-25 Calgene, Inc. Genmanipulierung von pflanzenthioesterasen und pflanzenthioesterasen mit neuer substratspezifität
US5955329A (en) * 1995-05-15 1999-09-21 Calgene, Inc. Engineering plant thioesterases for altered substrate specificity
US6150512A (en) * 1995-05-15 2000-11-21 Yuan; Ling Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity
WO1997012047A1 (en) * 1995-09-29 1997-04-03 Calgene, Inc. Plant stearoyl-acp thioesterase sequences and methods to increase stearate content in plant seed oils
WO1997016978A1 (en) * 1995-11-10 1997-05-15 Unilever N.V. Edible fat spread
CA2251786A1 (en) * 1996-04-15 1997-10-23 Anthony J. Del Vecchio Food products containing structured triglycerides
AR013633A1 (es) * 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US5972664A (en) * 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6075183A (en) * 1997-04-11 2000-06-13 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US7745694B1 (en) 1997-04-11 2010-06-29 Monsanto Technology Llc Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US6051754A (en) * 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US6331664B1 (en) 1997-05-05 2001-12-18 Dow Agrosciences Llc Acyl-ACP thioesterase nucleic acids from maize and methods of altering palmitic acid levels in transgenic plants therewith
US7455999B2 (en) * 1998-01-22 2008-11-25 Metabolix, Inc. Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate)
US6426448B1 (en) 1998-05-11 2002-07-30 E. I. Du Pont De Nemours And Company Gene combinations that alter the quality and functionality of soybean oil
US6365802B2 (en) 1998-08-14 2002-04-02 Calgene Llc Methods for increasing stearate content in soybean oil
US7592015B2 (en) 1999-06-04 2009-09-22 Consejo Superior De Investigaciones Cientificas Use of high oleic high stearic oils
US6388113B1 (en) 1999-06-04 2002-05-14 Consejo Superior De Investigaciones Cientificas ( Csic) High oleic/high stearic sunflower oils
WO2000074470A1 (en) 1999-06-04 2000-12-14 Consejo Superior De Investigaciones Cientificas High oleic high stearic plants, seeds and oils
BR0015641A (pt) * 1999-11-24 2002-07-09 Du Pont Polinucleotìdeo isolado, sequência de polinucleotìdeos, complemento isolado do polinucleotìdeo, molécula de ácido nucléico isolado, gene quimérico, célula, planta transgênica, método de transformação de uma célula, método de produção de uma planta transgênica, método de produção de um fragmento de polinucleotìdeo, método de alteração do nìvel de expressão de oleoil-acp tioesterase em uma célula hospedeira
WO2002008403A2 (en) 2000-07-25 2002-01-31 Calgene Llc Nucleic acid sequences encoding beta-ketoacyl-acp synthase and uses thereof
US8232078B2 (en) * 2001-11-28 2012-07-31 Bio-Rad Laboratories, Inc. Methods of using improved polymerases
EP2216405A1 (de) 2002-05-03 2010-08-11 Monsanto Technology LLC Saatspezifische USP-Promotoren zur Expression von Genen in Pflanzen
US7078234B2 (en) 2002-12-18 2006-07-18 Monsanto Technology Llc Maize embryo-specific promoter compositions and methods for use thereof
EP1613730A4 (de) 2003-03-28 2007-12-05 Monsanto Technology Llc Neue pflanzenpromotoren zur verwendung in der frühen samenentwicklungsphase
WO2006089950A2 (en) 2005-02-26 2006-08-31 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
US8034994B2 (en) * 2005-04-19 2011-10-11 Basf Plant Science Gmbh Starchy-endosperm and/or germinating embryo-specific expression in mono-cotyledonous plants
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PL2167667T3 (pl) 2007-07-09 2015-10-30 Bayer Cropscience Nv Roślina Brassica zawierająca zmutowane allele tłuszczowej tioesterazy acylo-ACP
JP2011508047A (ja) * 2007-12-27 2011-03-10 サイバス,エルエルシー アルキルエステル脂肪酸配合物およびその用途
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WO2011011568A2 (en) 2009-07-24 2011-01-27 The Regenst Of The University Of California Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms
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US9650655B2 (en) 2012-07-20 2017-05-16 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
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JP6491881B2 (ja) 2012-12-27 2019-03-27 花王株式会社 アシル−acpチオエステラーゼ
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US9567615B2 (en) 2013-01-29 2017-02-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
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US9783836B2 (en) 2013-03-15 2017-10-10 Terravia Holdings, Inc. Thioesterases and cells for production of tailored oils
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Also Published As

Publication number Publication date
CA2109580A1 (en) 1992-11-26
ATE262042T1 (de) 2004-04-15
US5512482A (en) 1996-04-30
ES2217253T3 (es) 2004-11-01
EP0557469A1 (de) 1993-09-01
EP0557469A4 (de) 1993-07-14
EP0557469B1 (de) 2004-03-17
WO1992020236A1 (en) 1992-11-26
DE69233323T2 (de) 2005-02-24
JP2002238386A (ja) 2002-08-27
CA2109580C (en) 2009-08-04

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