DE69224124D1 - Verfahren zur Herstellung von Dihomo-Gamma-Linolensäure und das in dieser enthaltende Lipid - Google Patents
Verfahren zur Herstellung von Dihomo-Gamma-Linolensäure und das in dieser enthaltende LipidInfo
- Publication number
- DE69224124D1 DE69224124D1 DE69224124T DE69224124T DE69224124D1 DE 69224124 D1 DE69224124 D1 DE 69224124D1 DE 69224124 T DE69224124 T DE 69224124T DE 69224124 T DE69224124 T DE 69224124T DE 69224124 D1 DE69224124 D1 DE 69224124D1
- Authority
- DE
- Germany
- Prior art keywords
- dihomo
- linolenic acid
- gamma
- preparation
- lipid contained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000002632 lipids Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 title 1
- 235000021298 Dihomo-γ-linolenic acid Nutrition 0.000 title 1
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 title 1
- 229960004488 linolenic acid Drugs 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Fats And Perfumes (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25196491A JP3354581B2 (ja) | 1991-09-30 | 1991-09-30 | ジホモ−γ−リノレン酸及びこれを含有する脂質の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69224124D1 true DE69224124D1 (de) | 1998-02-26 |
DE69224124T2 DE69224124T2 (de) | 1998-05-07 |
Family
ID=17230612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69224124T Expired - Lifetime DE69224124T2 (de) | 1991-09-30 | 1992-09-30 | Verfahren zur Herstellung von Dihomo-Gamma-Linolensäure und das in dieser enthaltende Lipid |
Country Status (9)
Country | Link |
---|---|
US (2) | US6280982B1 (de) |
EP (1) | EP0535940B1 (de) |
JP (1) | JP3354581B2 (de) |
AT (1) | ATE162551T1 (de) |
CA (1) | CA2079364C (de) |
DE (1) | DE69224124T2 (de) |
DK (1) | DK0535940T3 (de) |
ES (1) | ES2111052T3 (de) |
HK (1) | HK1007052A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3792309B2 (ja) | 1996-08-30 | 2006-07-05 | サントリー株式会社 | 不飽和脂肪酸含有油脂の製造方法 |
EP2308988A1 (de) | 1996-12-27 | 2011-04-13 | Suntory Holdings Limited | Medium zur Kultivierung von Mikroorganismen und Verfahren zur Herstellung von ungesättigten Fettsäuren oder Lipiden damit |
ATE408701T1 (de) * | 1997-03-04 | 2008-10-15 | Suntory Ltd | Verfahren zur herstellung von hochungesättigten fettsäuren und hochungesättigte fettsäuren enthaltendes lipid |
JP2000069987A (ja) | 1998-08-28 | 2000-03-07 | Suntory Ltd | アラキドン酸含有脂質並びにジホモ−γ−リノレン酸含有脂質の製造方法 |
ATE529502T1 (de) | 1999-08-13 | 2011-11-15 | Suntory Holdings Ltd | Lipidausscheidender mikroorganismus und verfahren zur herstellung des lipids und lipidkugeln mit darin eingeschlossenem lipid durch verwendung von mikroorganismen |
JP4088097B2 (ja) | 2002-04-26 | 2008-05-21 | サントリー株式会社 | 高度不飽和脂肪酸含有脂質の製造方法 |
KR101460259B1 (ko) | 2002-10-11 | 2014-11-10 | 닛폰 스이산 가부시키가이샤 | 불비누화 물질 함량을 저감시킨 미생물 유지의 제조 방법 및 그 유지 |
EP2239316A1 (de) | 2004-08-12 | 2010-10-13 | Nippon Suisan Kaisha, Ltd. | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuen unter Anwendung einer neuartigen Zellerhaltungstechnik |
US20080269329A1 (en) * | 2004-08-24 | 2008-10-30 | Shigeaki Fujikawa | Process for Production of Microbial Fat/Oil Containing Discretional Amount of Diacylglycerol and Said Fat/Oil |
JP4624040B2 (ja) | 2004-09-06 | 2011-02-02 | 日本水産株式会社 | 菌体培養方法 |
JP4849806B2 (ja) | 2005-02-08 | 2012-01-11 | 日本水産株式会社 | 新規な菌体処理方法を用いた高度不飽和脂肪酸の製造方法 |
CA2599112C (en) | 2005-02-14 | 2013-10-22 | Suntory Limited | Composition comprising dihomo-.gamma.-linolenic acid (dgla) as the active ingredient |
US8871808B2 (en) | 2006-06-22 | 2014-10-28 | Ben-Gurion University Of The Negev Research And Development Authority Et Al. | Over-production of dihomo linolenic acid by a mutant strain of Parietochloris incisa |
JP5101894B2 (ja) | 2007-01-15 | 2012-12-19 | サントリーホールディングス株式会社 | 高度不飽和脂肪酸及びこれを含有する脂質の製造方法 |
AU2007357796B2 (en) * | 2007-08-13 | 2014-05-08 | Ben-Gurion University Of The Negev Research And Development Authority | Over-production of dihomo gamma linolenic acid by a mutant strain of Parietochloris incisa |
GB0907413D0 (en) | 2009-04-29 | 2009-06-10 | Equateq Ltd | Novel methods |
WO2011154947A2 (en) * | 2010-06-10 | 2011-12-15 | Ben-Gurion University Of The Negev Research And Development Authority | D5 desaturase-defective mutant gene and use thereof |
EP2708230B1 (de) | 2011-05-12 | 2024-10-02 | Nissui Corporation | Zusammensetzung zur äusserlichen anwendung auf der haut für entzündliche erkrankungen |
EP2826384A1 (de) | 2013-07-16 | 2015-01-21 | Evonik Industries AG | Verfahren zur Trocknung von Biomasse |
JP6824038B2 (ja) * | 2013-12-04 | 2021-02-03 | 日本水産株式会社 | ジホモ−γ−リノレン酸含有微生物油及びジホモ−γ−リノレン酸含有微生物菌体 |
MX2016015961A (es) | 2014-06-04 | 2017-04-05 | Dignity Sciences Ltd | Composiciones farmacéuticas que comprenden ácido dihomo-gamma-linolénico (dgla) y uso de las mismas. |
ES2870093T3 (es) | 2014-10-02 | 2021-10-26 | Evonik Operations Gmbh | Biomasa que contiene PUFA con estabilidad celular elevada y su empleo para la producción de piensos |
US11324234B2 (en) | 2014-10-02 | 2022-05-10 | Evonik Operations Gmbh | Method for raising animals |
US11464244B2 (en) | 2014-10-02 | 2022-10-11 | Evonik Operations Gmbh | Feedstuff of high abrasion resistance and good stability in water, containing PUFAs |
EP3200606B1 (de) | 2014-10-02 | 2021-03-31 | Evonik Operations GmbH | Verfahren zur herstellung eines pufas enthaltenden futtermittels durch extrusion einer pufas enthaltenden biomasse des typs labyrinthulomycetes |
CN114040797A (zh) | 2018-12-28 | 2022-02-11 | 日本水产株式会社 | 花生四烯酸含量减少的含二高-γ-亚麻酸的微生物油 |
WO2021065659A1 (ja) | 2019-10-01 | 2021-04-08 | サントリーホールディングス株式会社 | アクアポリン3の発現調節を介した腸機能改善用組成物及びその使用 |
US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0722513B2 (ja) | 1986-07-08 | 1995-03-15 | サントリー株式会社 | ビスホモ―γ―リノレン酸及びこれを含有する脂質の製造方法 |
EP0273708B1 (de) | 1986-12-26 | 1994-03-23 | Sagami Chemical Research Center | Verfahren zur Herstellung von Eicosapentaensäure |
JPS6447384A (en) | 1987-08-19 | 1989-02-21 | Idemitsu Petrochemical Co | Production of lipid containing bis-homo-gamma-linolenic acid and/or arachidonic acid |
JPS6447385A (en) | 1987-08-19 | 1989-02-21 | Idemitsu Petrochemical Co | Production of lipid containing bis-homo-gamma-linolenic acid and/or arachidonic acid |
US5034321A (en) | 1987-08-19 | 1991-07-23 | Idemitsu Petrochemical Co., Ltd. | Method for the production of lipids containing bis-homo-γ-linolenic acid |
JP2746371B2 (ja) * | 1987-12-21 | 1998-05-06 | サントリー株式会社 | ビスホモ−γ−リノレン酸及びこれを含有する脂質の製造方法 |
JPH01228486A (ja) | 1988-03-09 | 1989-09-12 | Suntory Ltd | 奇数鎖高度不飽和脂肪酸及びこれを含有する脂質の製造方法 |
JPH02268690A (ja) | 1989-04-10 | 1990-11-02 | Idemitsu Petrochem Co Ltd | ビスホモ―γ―リノレン酸含有脂質の製造法 |
JP2740854B2 (ja) | 1989-07-18 | 1998-04-15 | 出光石油化学株式会社 | ジホモ―γ―リノレン酸の製造法および脂肪酸の△5位不飽和化反応抑制剤 |
JP2958361B2 (ja) | 1989-05-24 | 1999-10-06 | 出光石油化学株式会社 | ジホモ―γ―リノレン酸の製造法および脂肪酸の△5位不飽和化反応抑制剤 |
US5093249A (en) | 1989-05-24 | 1992-03-03 | Idemitsu Petrochemical Co., Ltd. | Process for production of dihomo-γ-linolenic acid and inhibitor for unsaturation reaction at Δ5-position of fatty acid |
US5997852A (en) * | 1995-01-18 | 1999-12-07 | Taisho Pharmaceutical Co., Ltd. | Remedy for dermatitis |
US6107334A (en) * | 1998-02-23 | 2000-08-22 | Wake Forest University | Dietary control of arachidonic acid metabolism |
-
1991
- 1991-09-30 JP JP25196491A patent/JP3354581B2/ja not_active Expired - Lifetime
-
1992
- 1992-09-29 CA CA002079364A patent/CA2079364C/en not_active Expired - Lifetime
- 1992-09-30 DK DK92308928.8T patent/DK0535940T3/da active
- 1992-09-30 DE DE69224124T patent/DE69224124T2/de not_active Expired - Lifetime
- 1992-09-30 ES ES92308928T patent/ES2111052T3/es not_active Expired - Lifetime
- 1992-09-30 EP EP92308928A patent/EP0535940B1/de not_active Expired - Lifetime
- 1992-09-30 AT AT92308928T patent/ATE162551T1/de active
-
1994
- 1994-04-20 US US08/230,879 patent/US6280982B1/en not_active Expired - Lifetime
-
1998
- 1998-06-23 HK HK98106120A patent/HK1007052A1/xx not_active IP Right Cessation
-
2001
- 2001-01-18 US US09/761,828 patent/US6602690B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2079364C (en) | 2003-04-08 |
JP3354581B2 (ja) | 2002-12-09 |
US6602690B2 (en) | 2003-08-05 |
EP0535940B1 (de) | 1998-01-21 |
CA2079364A1 (en) | 1993-03-31 |
ATE162551T1 (de) | 1998-02-15 |
DE69224124T2 (de) | 1998-05-07 |
HK1007052A1 (en) | 1999-03-26 |
US6280982B1 (en) | 2001-08-28 |
DK0535940T3 (da) | 1998-04-27 |
JPH0591887A (ja) | 1993-04-16 |
ES2111052T3 (es) | 1998-03-01 |
US20010021522A1 (en) | 2001-09-13 |
EP0535940A1 (de) | 1993-04-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: SUNTORY HOLDINGS LTD., OSAKA, JP |
|
R071 | Expiry of right |
Ref document number: 535940 Country of ref document: EP |