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DE69205566D1 - Herpes-simplex-impfstoff, der hsv-glycoprotein-gd und 3-deacyl monophosphoryl-lipid-a enthaelt. - Google Patents

Herpes-simplex-impfstoff, der hsv-glycoprotein-gd und 3-deacyl monophosphoryl-lipid-a enthaelt.

Info

Publication number
DE69205566D1
DE69205566D1 DE69205566T DE69205566T DE69205566D1 DE 69205566 D1 DE69205566 D1 DE 69205566D1 DE 69205566 T DE69205566 T DE 69205566T DE 69205566 T DE69205566 T DE 69205566T DE 69205566 D1 DE69205566 D1 DE 69205566D1
Authority
DE
Germany
Prior art keywords
enthaelt
impfstoff
hsv
simplex
herpes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69205566T
Other languages
English (en)
Other versions
DE69205566T3 (de
DE69205566T2 (de
Inventor
Myriam Francotte
Jean-Paul Prieels
Moncef Slaoui
Nathalie Garcon-Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10691946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69205566(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by SmithKline Beecham Biologicals SA filed Critical SmithKline Beecham Biologicals SA
Publication of DE69205566D1 publication Critical patent/DE69205566D1/de
Application granted granted Critical
Publication of DE69205566T2 publication Critical patent/DE69205566T2/de
Publication of DE69205566T3 publication Critical patent/DE69205566T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69205566T 1991-03-21 1992-03-17 Herpes-simplex-impfstoff, der hsv-glycoprotein-gd und 3-deacyl monophosphoryl-lipid-a enthaelt. Expired - Lifetime DE69205566T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9105992A GB9105992D0 (en) 1991-03-21 1991-03-21 Vaccine
PCT/EP1992/000592 WO1992016231A1 (en) 1991-03-21 1992-03-17 HERPES SIMPLEX VACCINE COMPRISING HSV GLYCOPROTEIN gD AND 3 dEACYLATED MONOPHOSPHORYL LIPID A

Publications (3)

Publication Number Publication Date
DE69205566D1 true DE69205566D1 (en) 1995-11-23
DE69205566T2 DE69205566T2 (de) 1996-04-18
DE69205566T3 DE69205566T3 (de) 2002-09-05

Family

ID=10691946

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69205566T Expired - Lifetime DE69205566T3 (de) 1991-03-21 1992-03-17 Herpes-simplex-impfstoff, der hsv-glycoprotein-gd und 3-deacyl monophosphoryl-lipid-a enthaelt.

Country Status (34)

Country Link
US (1) US6027730A (de)
EP (1) EP0576478B2 (de)
JP (1) JP3530526B2 (de)
KR (1) KR100224329B1 (de)
CN (2) CN1058191C (de)
AP (1) AP298A (de)
AT (1) ATE129160T1 (de)
AU (1) AU650521B2 (de)
BR (1) BR9205745A (de)
CA (1) CA2106492C (de)
CY (1) CY1936A (de)
CZ (1) CZ280505B6 (de)
DE (1) DE69205566T3 (de)
DK (1) DK0576478T4 (de)
ES (1) ES2081102T5 (de)
FI (1) FI107881B (de)
GB (1) GB9105992D0 (de)
GR (1) GR3017884T3 (de)
HK (1) HK1004525A1 (de)
HU (1) HU218025B (de)
IE (1) IE69560B1 (de)
IL (1) IL101290A (de)
MA (1) MA22471A1 (de)
MX (1) MX9201245A (de)
MY (1) MY110086A (de)
NO (1) NO307499B1 (de)
NZ (1) NZ242057A (de)
PL (1) PL170059B1 (de)
PT (1) PT100262B (de)
SA (1) SA92120459B1 (de)
SK (1) SK279190B6 (de)
WO (1) WO1992016231A1 (de)
YU (1) YU28392A (de)
ZA (1) ZA922011B (de)

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DE69428136T3 (de) * 1993-03-23 2008-07-10 Smithkline Beecham Biologicals S.A. 3-0-Deazylierte Monophosphoryl Lipid A enthaltende Impfstoff-Zusammensetzungen
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CA2209360C (en) 1994-12-28 2010-07-06 University Of Kentucky Recombinant monoclonal anti-idiotype antibody 3h1 sequences relating to human carcinoembryonic antigen
US6949244B1 (en) 1995-12-20 2005-09-27 The Board Of Trustees Of The University Of Kentucky Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof
US6235280B1 (en) 1996-04-12 2001-05-22 Malaya Chatterjee Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1
US20020041872A1 (en) 1996-04-12 2002-04-11 Malaya Chatterjee Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1
US6468782B1 (en) 1996-12-05 2002-10-22 Quadrant Healthcare (Uk) Limited Methods of preserving prokaryotic cells and compositions obtained thereby
US6274143B1 (en) 1997-06-13 2001-08-14 Malaya Chatterjee Methods of delaying development of HMFG-associated tumors using anti-idiotype antibody 11D10
US6355244B1 (en) 1997-11-17 2002-03-12 University Of Kentucky Research Foundation Methods and compositions for the treatment of psoriasis
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US9273326B2 (en) 2004-04-30 2016-03-01 The Brigham And Women's Hospital, Inc. Tetracycline-regulated gene expression in HSV-1 vectors
EP2305296A1 (de) 2004-09-22 2011-04-06 GlaxoSmithKline Biologicals SA Immunogene Zusammensetzung zur Verwendung zur Impfung gegen Staphylokokken
JP2008534467A (ja) 2005-03-23 2008-08-28 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 組成物
SI2384765T1 (sl) 2005-12-22 2017-03-31 Glaxosmithkline Biologicals S.A. Streptococcus pneumoniae vakcina
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
MX337528B (es) 2006-03-30 2016-03-09 Glaxosmithkline Biolog Sa Composición inmunogénica que comprende un sacárido capsular estafilocócico o-acetilado y una proteína estafilocócica.
JP5639760B2 (ja) 2006-07-17 2014-12-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム インフルエンザワクチン
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
EP2468300B1 (de) 2006-09-26 2017-12-20 Infectious Disease Research Institute Impfstoffzusammensetzung mit einem synthetischen Adjuvans
TW200908994A (en) 2007-04-20 2009-03-01 Glaxosmithkline Biolog Sa Vaccine
MX2009013949A (es) 2007-06-26 2010-05-24 Glaxosmithkline Biolog Sa Vacuna que comprende conjugados de polisacárido capsular de streptococcus pneumoniae.
CN102458463B (zh) 2009-05-22 2017-01-18 健诺西生物科学公司 针对ⅱ型单纯疱疹病毒的疫苗:诱发免疫应答的组合物和方法
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EP3329936A1 (de) 2011-08-22 2018-06-06 Nanobio Corporation Impfstoff gegen den herpes-simplex-virus als nanoemulsion
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EP2941269B1 (de) 2013-01-07 2020-12-09 Mucosal Vaccine Technologies LLC Therapeutische impfstoffe zur behandlung von herpes-simplex-virus-typ 2-infektionen
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WO1994019013A1 (en) * 1993-02-19 1994-09-01 Smithkline Beecham Corporation Influenza vaccine compositions containing 3-o-deacylated monophosphoryl lipid a
DE69428136T3 (de) * 1993-03-23 2008-07-10 Smithkline Beecham Biologicals S.A. 3-0-Deazylierte Monophosphoryl Lipid A enthaltende Impfstoff-Zusammensetzungen
WO1994027636A1 (en) * 1993-05-25 1994-12-08 American Cyanamid Company Adjuvants for vaccines against respiratory syncytial virus

Also Published As

Publication number Publication date
CN1201692A (zh) 1998-12-16
EP0576478B2 (de) 2001-04-18
DK0576478T3 (da) 1995-12-04
CZ280505B6 (cs) 1996-02-14
DK0576478T4 (da) 2001-07-23
MX9201245A (es) 1992-10-01
PL170059B1 (pl) 1996-10-31
CA2106492C (en) 2003-12-09
KR100224329B1 (ko) 1999-10-15
DE69205566T3 (de) 2002-09-05
FI934134A (fi) 1993-09-21
NO933343D0 (no) 1993-09-20
IL101290A (en) 1996-07-23
CN1101226C (zh) 2003-02-12
MA22471A1 (fr) 1992-10-01
US6027730A (en) 2000-02-22
EP0576478A1 (de) 1994-01-05
SK279190B6 (sk) 1998-07-08
ES2081102T3 (es) 1996-02-16
ES2081102T5 (es) 2001-09-01
AP9200368A0 (en) 1992-04-30
FI107881B (fi) 2001-10-31
ATE129160T1 (de) 1995-11-15
CY1936A (en) 1992-03-17
NZ242057A (en) 1993-12-23
HUT67052A (en) 1995-01-30
AP298A (en) 1994-01-14
JP3530526B2 (ja) 2004-05-24
MY110086A (en) 1997-12-31
CZ195893A3 (en) 1994-07-13
HK1004525A1 (en) 1998-11-27
SK94693A3 (en) 1994-05-11
IE69560B1 (en) 1996-10-02
HU218025B (hu) 2000-05-28
CA2106492A1 (en) 1992-09-22
ZA922011B (en) 1993-01-27
PT100262B (pt) 2001-05-31
BR9205745A (pt) 1994-10-18
SA92120459B1 (ar) 2005-06-14
PT100262A (pt) 1993-06-30
EP0576478B1 (de) 1995-10-18
GR3017884T3 (en) 1996-01-31
YU28392A (sh) 1994-11-15
AU650521B2 (en) 1994-06-23
IE920881A1 (en) 1992-09-23
WO1992016231A1 (en) 1992-10-01
GB9105992D0 (en) 1991-05-08
CN1058191C (zh) 2000-11-08
FI934134A0 (fi) 1993-09-21
CN1065997A (zh) 1992-11-11
IL101290A0 (en) 1992-11-15
DE69205566T2 (de) 1996-04-18
JPH06505727A (ja) 1994-06-30
NO307499B1 (no) 2000-04-17
AU1365792A (en) 1992-10-21
NO933343L (no) 1993-09-20
HU9302645D0 (en) 1994-01-28

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