DE69126568D1 - Neues physiologisch aktives Schweinepeptid (CNP-53) - Google Patents

Neues physiologisch aktives Schweinepeptid (CNP-53)

Info

Publication number: DE69126568D1
Authority: DE; Germany
Prior art keywords: cnp; physiologically active; new physiologically; active pig; peptide
Prior art date: 1990-07-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69126568T

Other languages

English (en)

Other versions

DE69126568T2 (de

Inventor

Hisayuki Matsuo

Kenji Kangawa

Naoto Minamino

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-13

Filing date

1991-07-12

Publication date

1997-07-24

1991-07-12 Application filed by Individual filed Critical Individual

1997-07-24 Publication of DE69126568D1 publication Critical patent/DE69126568D1/de

1997-11-27 Application granted granted Critical

1997-11-27 Publication of DE69126568T2 publication Critical patent/DE69126568T2/de

2011-07-13 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
102000012421 C-Type Natriuretic Peptide Human genes 0.000 title 1
101800000060 C-type natriuretic peptide Proteins 0.000 title 1
101800000433 CNP-53 Proteins 0.000 title 1
UHSBKBYWHCBDCJ-DYGWFTAGSA-N natriuretic peptide, c-type Chemical compound N1C(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)CN)CSSC[C@@H](C(O)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H]1CC1=CC=CC=C1 UHSBKBYWHCBDCJ-DYGWFTAGSA-N 0.000 title 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 2
125000000539 amino acid group Chemical group 0.000 abstract 1
239000002934 diuretic Substances 0.000 abstract 1
230000001077 hypotensive effect Effects 0.000 abstract 1
230000001452 natriuretic effect Effects 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Animal Behavior & Ethology (AREA)
Biophysics (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Diabetes (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DE69126568T 1990-07-13 1991-07-12 Neues physiologisch aktives Schweinepeptid (CNP-53) Expired - Lifetime DE69126568T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2186582A JP2930380B2 (ja)	1990-07-13	1990-07-13	ブタ由来新規生理活性ペプチド（ｃｎｐ―５３）

Publications (2)

Publication Number	Publication Date
DE69126568D1 true DE69126568D1 (de)	1997-07-24
DE69126568T2 DE69126568T2 (de)	1997-11-27

Family

ID=16191066

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69126568T Expired - Lifetime DE69126568T2 (de)	1990-07-13	1991-07-12	Neues physiologisch aktives Schweinepeptid (CNP-53)

Country Status (8)

Country	Link
US (1)	US5340920A (de)
EP (1)	EP0466174B1 (de)
JP (1)	JP2930380B2 (de)
AT (1)	ATE154641T1 (de)
DE (1)	DE69126568T2 (de)
DK (1)	DK0466174T3 (de)
ES (1)	ES2104635T3 (de)
GR (1)	GR3024581T3 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100691545B1 (ko) *	1998-09-28	2007-03-09	산텐 세이야꾸 가부시키가이샤	나트륨 이뇨 펩티드를 유효 성분으로하는 누액 분비 촉진또는 각결막 장해 치료용 점안제
BRPI0203172B8 (pt)	2001-09-28	2021-05-25	Nakao Kazuwa	composição farmacêutica para acondroplasia
CN1960758B (zh) *	2004-03-31	2014-10-22	中外制药株式会社	关节炎的治疗剂或预防剂
CN1960757A (zh)	2004-03-31	2007-05-09	中尾一和	身高增加用组合物
DK2348114T3 (en)	2004-04-21	2018-09-03	Alexion Pharma Inc	BONE DELIVERY CONJUGATES AND PROCEDURE TO USE IT FOR TARGETING PROTEINS AGAINST BONE
AR069409A1 (es)	2007-11-21	2010-01-20	Biomarin Pharm Inc	Variantes de peptidos natriureticos de tipo c
KR102225470B1 (ko)	2009-05-20	2021-03-10	바이오마린 파머수티컬 인크.	씨형 나트륨이뇨 펩티드의 변이체
US9266939B2 (en)	2010-12-27	2016-02-23	Alexion Pharmaceuticals, Inc.	Compositions comprising natriuretic peptides and methods of use thereof
WO2013058833A1 (en)	2011-10-19	2013-04-25	Enobia Canada Limited Partnership	Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
US10052366B2 (en)	2012-05-21	2018-08-21	Alexion Pharmaceuticsl, Inc.	Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
US10822596B2 (en)	2014-07-11	2020-11-03	Alexion Pharmaceuticals, Inc.	Compositions and methods for treating craniosynostosis
WO2016090251A1 (en)	2014-12-05	2016-06-09	Alexion Pharmaceuticals, Inc.	Treating seizure with recombinant alkaline phosphatase
AU2016211447B2 (en)	2015-01-28	2021-09-23	Alexion Pharmaceuticals, Inc.	Methods of treating a subject with an alkaline phosphatase deficiency
HK1257341A1 (zh)	2015-08-17	2019-10-18	Alexion Pharmaceuticals, Inc.	鹼性磷酸酯的製造
WO2017058822A1 (en)	2015-09-28	2017-04-06	Alexion Pharmaceuticals, Inc.	Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia
JP2018533571A (ja)	2015-10-30	2018-11-15	アレクシオンファーマシューティカルズ，インコーポレイテッド	患者の頭蓋縫合早期癒合症を治療するための方法
EP3426286A4 (de)	2016-03-08	2019-12-04	Alexion Pharmaceuticals, Inc.	Verfahren zur behandlung von hypophosphatasie bei kindern
EP3436020A4 (de)	2016-04-01	2019-12-25	Alexion Pharmaceuticals, Inc.	Verfahren zur behandlung von hypophosphatasie bei jugendlichen und erwachsenen
US11186832B2 (en)	2016-04-01	2021-11-30	Alexion Pharmaceuticals, Inc.	Treating muscle weakness with alkaline phosphatases
EP3464573A4 (de)	2016-06-06	2020-02-19	Alexion Pharmaceuticals, Inc.	Auswirkungen von metallen auf die herstellung von alkalischen phosphatasen
US11116821B2 (en)	2016-08-18	2021-09-14	Alexion Pharmaceuticals, Inc.	Methods for treating tracheobronchomalacia
AU2018243320B2 (en)	2017-03-31	2025-03-27	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia (HPP) in adults and adolescents
WO2019190752A1 (en)	2018-03-30	2019-10-03	Alexion Pharmaceuticals, Inc.	Manufacturing of glycoproteins
WO2020033867A2 (en)	2018-08-10	2020-02-13	Alexion Pharmaceuticals, Inc.	Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase
WO2022173987A1 (en)	2021-02-12	2022-08-18	Alexion Pharmaceuticals, Inc.	Alkaline phosphatase polypeptides and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2544929B2 (ja) *	1987-06-17	1996-10-16	第一化学薬品株式会社	新規生理活性ペプチド
US5114923A (en) *	1988-05-31	1992-05-19	California Biotechnology Inc.	Recombinant techniques for production of novel natriuretic and vasodilator peptides

1990
- 1990-07-13 JP JP2186582A patent/JP2930380B2/ja not_active Expired - Lifetime
1991
- 1991-07-12 AT AT91111629T patent/ATE154641T1/de not_active IP Right Cessation
- 1991-07-12 DK DK91111629.1T patent/DK0466174T3/da active
- 1991-07-12 EP EP91111629A patent/EP0466174B1/de not_active Expired - Lifetime
- 1991-07-12 ES ES91111629T patent/ES2104635T3/es not_active Expired - Lifetime
- 1991-07-12 US US07/728,221 patent/US5340920A/en not_active Expired - Lifetime
- 1991-07-12 DE DE69126568T patent/DE69126568T2/de not_active Expired - Lifetime
1997
- 1997-08-29 GR GR970402223T patent/GR3024581T3/el unknown

Also Published As

Publication number	Publication date
JP2930380B2 (ja)	1999-08-03
DK0466174T3 (da)	1998-01-12
JPH0474198A (ja)	1992-03-09
US5340920A (en)	1994-08-23
EP0466174A1 (de)	1992-01-15
ATE154641T1 (de)	1997-07-15
EP0466174B1 (de)	1997-06-18
ES2104635T3 (es)	1997-10-16
GR3024581T3 (en)	1997-12-31
DE69126568T2 (de)	1997-11-27

Publication	Publication Date	Title
DE69126568D1 (de)	1997-07-24	Neues physiologisch aktives Schweinepeptid (CNP-53)
IL74426A (en)	1989-09-10	Atrial peptides and pharmaceutical compositions comprising them
DK1188768T3 (da)	2009-09-21	LHRH-antagonisk-peptider
DE69233068D1 (de)	2003-06-26	Serin-reiche peptidlinker
SE8605189L (sv)	1987-06-05	Nya kalcitoninderivat
DK0466175T3 (da)	1998-09-07	Porcint CNP-gen og præcursor-protein
NO971621D0 (no)	1997-04-09	Keratinocyttvekstfaktoranaloger
BG97123A (bg)	1993-12-24	Производни на човешка, стимулирана от жлъчните соли, липаза и фармацевтични състави на тяхна основа
SE9603468D0 (sv)	1996-09-23	New compounds
SE7712634L (sv)	1978-05-12	Ny polypeptid med serumkalciumreducerande aktivitet
SE8702520D0 (sv)	1987-06-16	Mammal intestine hormone precursor
DK0490383T3 (da)	1997-02-17	Peptider af HIV-gag-proteinet, fremstilling og anvendelse deraf
AU2254588A (en)	1989-03-09	Biologically active segments of several growth hormones
EP0687685A4 (de)	1998-07-01	Physiologisch-aktive peptide
EP0441763A3 (en)	1992-01-15	Heparin-binding growth factor
DE3882233D1 (de)	1993-08-12	Gefaessaktive peptide.
SE9603461D0 (sv)	1996-09-23	New compounds
SE9603463D0 (sv)	1996-09-23	New compounds
SE9603462D0 (sv)	1996-09-23	New compounds
DK53290A (da)	1990-03-01	Syntetiske gaer-leader-peptider

Legal Events

Date	Code	Title	Description
1998-07-16	8364	No opposition during term of opposition