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DE69942459D1 - Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung - Google Patents

Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung

Info

Publication number
DE69942459D1
DE69942459D1 DE69942459T DE69942459T DE69942459D1 DE 69942459 D1 DE69942459 D1 DE 69942459D1 DE 69942459 T DE69942459 T DE 69942459T DE 69942459 T DE69942459 T DE 69942459T DE 69942459 D1 DE69942459 D1 DE 69942459D1
Authority
DE
Germany
Prior art keywords
nucleic acid
acid molecules
tif
copying
isolated nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69942459T
Other languages
English (en)
Inventor
Laure Dumoutier
Jamila Louhed
Jean-Christophe Renauld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Priority claimed from PCT/US1999/024424 external-priority patent/WO2000024758A1/en
Application granted granted Critical
Publication of DE69942459D1 publication Critical patent/DE69942459D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69942459T 1998-10-26 1999-10-18 Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung Expired - Lifetime DE69942459D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/178,973 US6274710B1 (en) 1998-10-26 1998-10-26 Antibodies which specifically bind T Cell inducible factors (TIFs)
US09/354,243 US6359117B1 (en) 1998-10-26 1999-07-16 Isolated nucleic acid molecules which encode T cell inducible factors (TIFs), the proteins encoded, and uses therefor
PCT/US1999/024424 WO2000024758A1 (en) 1998-10-26 1999-10-18 ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE T CELL INDUCIBLE FACTORS (TIFs), THE PROTEINS ENCODED, AND USES THEREOF

Publications (1)

Publication Number Publication Date
DE69942459D1 true DE69942459D1 (de) 2010-07-15

Family

ID=22654680

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69942459T Expired - Lifetime DE69942459D1 (de) 1998-10-26 1999-10-18 Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung

Country Status (5)

Country Link
US (3) US6274710B1 (de)
CN (1) CN1789411A (de)
AT (1) ATE469911T1 (de)
DE (1) DE69942459D1 (de)
ES (1) ES2346831T3 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
US6551799B2 (en) * 1999-12-07 2003-04-22 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US6274710B1 (en) * 1998-10-26 2001-08-14 Ludwig Institute For Cancer Research Antibodies which specifically bind T Cell inducible factors (TIFs)
US7081528B2 (en) * 1998-10-26 2006-07-25 Ludwig Institute For Cancer Research Isolated nucleic acid molecules encoding T cell derived inducible factors
US7307161B1 (en) * 1999-04-28 2007-12-11 Genetics Institute, Llc Human Gil-19/AE289 polynucleotides
US6939545B2 (en) 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
WO2000065027A2 (en) * 1999-04-28 2000-11-02 Genetics Institute, Inc. Human gil-19/ae289 proteins and polynucleotides encoding same
DE60043895D1 (de) * 1999-12-03 2010-04-08 Zymogenetics Inc Menschliches zytokinrezeptor
US7226591B2 (en) * 2000-05-22 2007-06-05 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
US20030012788A1 (en) * 2000-07-27 2003-01-16 Jean-Christophe Renauld Method for influencing kinase pathways with IL-22
DE60123998T2 (de) * 2000-08-08 2007-09-06 Zymogenetics, Inc., Seattle Lösliche zcyctor 11 cytokinrezeptoren
US7638604B2 (en) * 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
US20030099608A1 (en) * 2001-03-27 2003-05-29 Presnell Scott R. Human cytokine receptor
JP4504023B2 (ja) * 2002-03-22 2010-07-14 ザイモジェネティクス インコーポレーティッド 抗ｉｌ−ｔｉｆ抗体および炎症において使用する方法
CN102690350A (zh) * 2003-03-24 2012-09-26 津莫吉尼蒂克斯公司 抗il-22ra抗体和结合伴侣以及在炎症中的使用方法
ES2347672T3 (es) * 2004-10-22 2010-11-03 Zymogenetics, Inc. Anticuerpos dirigidos contra il-22ra y compañeros de union procedimientos de uso en enefermedades inflamatorias.
CN100515491C (zh) * 2005-01-04 2009-07-22 健能隆医药技术（上海）有限公司 白介素-22的医药用途
JP2008532931A (ja) * 2005-02-08 2008-08-21 ザイモジェネティクス， インコーポレイテッド 抗ｉｌ−２０、抗ｉｌ−２２および抗ｉｌ−２２ｒａ抗体ならびに結合パートナー、ならびに炎症における使用法
EP1954719A2 (de) * 2005-12-02 2008-08-13 Genentech Inc. Zusammensetzungen und verfahren zur behandlung von krankheiten und leiden in zusammenhang mit zytokin-signalisierung sowie unter verwendung an il-22 und il-22r bindender antikörper
TW200744634A (en) * 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
TWI417301B (zh) 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途
CN101361968B (zh) 2007-08-06 2011-08-03 健能隆医药技术（上海）有限公司 白介素-22在治疗脂肪肝中的应用
CN102260343A (zh) 2010-05-25 2011-11-30 健能隆医药技术（上海）有限公司 重组人g-csf二聚体在治疗神经损伤疾病中的用途
CN102380091A (zh) 2010-08-31 2012-03-21 健能隆医药技术（上海）有限公司 白介素-22在治疗病毒性肝炎中的应用
AU2012289433B2 (en) 2011-07-25 2017-07-27 Evive Biotechnology (Shanghai) Ltd Use of G-CSF dimer in preparation of medicament for treatment of neurodegenerative diseases
CN103182072B (zh) 2011-12-27 2017-05-03 健能隆医药技术（上海）有限公司 白介素‑22在治疗和预防神经损伤疾病或神经退行性疾病中的用途
US20150246095A1 (en) 2012-10-03 2015-09-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza
EP3065777B2 (de) 2013-11-07 2023-07-12 Memorial Sloan-Kettering Cancer Center Il-22 zur verwendung in der behandlung von gastrointestinaler graft-versus- host-reaktion
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 Il-22二聚体在制备静脉注射药物中的应用
CN104623639A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 白介素22二聚体在制备治疗胰腺炎药物中的应用
EP3167892A1 (de) 2015-11-10 2017-05-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Verfahren und pharmazeutische zusammensetzungen zur vorbeugung oder behandlung von entzündlichen darmerkrankungen
US11510966B2 (en) 2016-04-15 2022-11-29 Evive Biotechnology (Shanghai) Ltd Use of IL-22 in treating necrotizing enterocolitis
KR20210019464A (ko) 2018-06-05 2021-02-22 바이오아트라, 인코퍼레이티드 항 il-22 항체, 항체 단편, 이의 면역접합체 및 이의 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4208799A (en) 1998-05-29 1999-12-13 Human Genome Sciences, Inc. Interleukins-21 and 22
US6274710B1 (en) 1998-10-26 2001-08-14 Ludwig Institute For Cancer Research Antibodies which specifically bind T Cell inducible factors (TIFs)
US7081528B2 (en) * 1998-10-26 2006-07-25 Ludwig Institute For Cancer Research Isolated nucleic acid molecules encoding T cell derived inducible factors
US6331613B1 (en) 1998-10-26 2001-12-18 Ludwig Institue For Cancer Research Isolated nucleic acid molecules which encode T cell inducible factors (TIFS), the proteins encoded, and uses thereof
US7307161B1 (en) * 1999-04-28 2007-12-11 Genetics Institute, Llc Human Gil-19/AE289 polynucleotides
US6939545B2 (en) 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
WO2000065027A2 (en) * 1999-04-28 2000-11-02 Genetics Institute, Inc. Human gil-19/ae289 proteins and polynucleotides encoding same
AU5047600A (en) 1999-05-27 2000-12-18 Schering Corporation Mammalian interleukin-10 homologs: il-d110 and il-d210
US20030012788A1 (en) 2000-07-27 2003-01-16 Jean-Christophe Renauld Method for influencing kinase pathways with IL-22

Also Published As

Publication number Publication date
US7972833B2 (en) 2011-07-05
US20080213881A1 (en) 2008-09-04
US6359117B1 (en) 2002-03-19
ES2346831T3 (es) 2010-10-20
CN1789411A (zh) 2006-06-21
US6274710B1 (en) 2001-08-14
ATE469911T1 (de) 2010-06-15

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