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DE69834195D1 - Stabilisierte tramadol formulierungen mit verzögerter freisetzung - Google Patents

Stabilisierte tramadol formulierungen mit verzögerter freisetzung

Info

Publication number
DE69834195D1
DE69834195D1 DE69834195T DE69834195T DE69834195D1 DE 69834195 D1 DE69834195 D1 DE 69834195D1 DE 69834195 T DE69834195 T DE 69834195T DE 69834195 T DE69834195 T DE 69834195T DE 69834195 D1 DE69834195 D1 DE 69834195D1
Authority
DE
Germany
Prior art keywords
tramadol
stabilized
matrix
dosage form
storage conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69834195T
Other languages
English (en)
Other versions
DE69834195T2 (de
Inventor
Benjamin Oshlack
Hua-Pin Huang
Mark Chasin
Paul Goldenheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Publication of DE69834195D1 publication Critical patent/DE69834195D1/de
Application granted granted Critical
Publication of DE69834195T2 publication Critical patent/DE69834195T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69834195T 1997-07-02 1998-07-02 Stabilisierte tramadol formulierungen mit verzögerter freisetzung Expired - Lifetime DE69834195T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5160297P 1997-07-02 1997-07-02
US51602 1997-07-02
PCT/US1998/014087 WO1999001111A1 (en) 1997-07-02 1998-07-02 Stabilized sustained release tramadol formulations

Publications (2)

Publication Number Publication Date
DE69834195D1 true DE69834195D1 (de) 2006-05-24
DE69834195T2 DE69834195T2 (de) 2007-03-29

Family

ID=21972304

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69834195T Expired - Lifetime DE69834195T2 (de) 1997-07-02 1998-07-02 Stabilisierte tramadol formulierungen mit verzögerter freisetzung

Country Status (12)

Country Link
US (2) US6306438B1 (de)
EP (1) EP1009387B1 (de)
JP (2) JP3739410B2 (de)
AT (1) ATE322892T1 (de)
AU (1) AU8293498A (de)
CA (1) CA2270975C (de)
CY (1) CY1106112T1 (de)
DE (1) DE69834195T2 (de)
DK (1) DK1009387T3 (de)
ES (1) ES2263211T3 (de)
PT (1) PT1009387E (de)
WO (1) WO1999001111A1 (de)

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US6645527B2 (en) 2003-11-11
US20020102302A1 (en) 2002-08-01
DK1009387T3 (da) 2006-08-14
EP1009387B1 (de) 2006-04-12
CY1106112T1 (el) 2011-06-08
PT1009387E (pt) 2006-08-31
US6306438B1 (en) 2001-10-23
JP2004002419A (ja) 2004-01-08
AU8293498A (en) 1999-01-25
EP1009387A1 (de) 2000-06-21
ES2263211T3 (es) 2006-12-01
DE69834195T2 (de) 2007-03-29
CA2270975C (en) 2003-04-01
WO1999001111A1 (en) 1999-01-14
CA2270975A1 (en) 1999-01-14
ATE322892T1 (de) 2006-04-15
JP2000510487A (ja) 2000-08-15
JP3739410B2 (ja) 2006-01-25
EP1009387A4 (de) 2004-08-25

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