DE69733958D1 - Verfahren zur positionierung von klonen mittels molekularen kaemmens - Google Patents
Verfahren zur positionierung von klonen mittels molekularen kaemmensInfo
- Publication number
- DE69733958D1 DE69733958D1 DE69733958T DE69733958T DE69733958D1 DE 69733958 D1 DE69733958 D1 DE 69733958D1 DE 69733958 T DE69733958 T DE 69733958T DE 69733958 T DE69733958 T DE 69733958T DE 69733958 D1 DE69733958 D1 DE 69733958D1
- Authority
- DE
- Germany
- Prior art keywords
- dna
- probes
- several
- reacting
- combing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/10—Ploidy or copy number detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Lasers (AREA)
- Control Of Stepping Motors (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Position Fixing By Use Of Radio Waves (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9613276A FR2755147B1 (fr) | 1996-10-30 | 1996-10-30 | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
FR9613276 | 1996-10-30 | ||
FR9702999A FR2755149B1 (fr) | 1996-10-30 | 1997-03-13 | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
FR9702999 | 1997-03-13 | ||
PCT/FR1997/001949 WO1998018959A1 (fr) | 1996-10-30 | 1997-10-30 | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69733958D1 true DE69733958D1 (de) | 2005-09-15 |
DE69733958T2 DE69733958T2 (de) | 2006-05-18 |
Family
ID=26233071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69733958T Expired - Lifetime DE69733958T2 (de) | 1996-10-30 | 1997-10-30 | Verfahren zur positionierung von klonen mittels molekularen kaemmens |
Country Status (10)
Country | Link |
---|---|
US (4) | US6344319B1 (de) |
EP (1) | EP0935674B1 (de) |
JP (3) | JP4226078B2 (de) |
AT (1) | ATE301724T1 (de) |
AU (1) | AU4953397A (de) |
DE (1) | DE69733958T2 (de) |
DK (1) | DK0935674T3 (de) |
ES (1) | ES2247623T3 (de) |
FR (1) | FR2755149B1 (de) |
WO (1) | WO1998018959A1 (de) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2755149B1 (fr) * | 1996-10-30 | 1999-01-15 | Pasteur Institut | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
US6696022B1 (en) * | 1999-08-13 | 2004-02-24 | U.S. Genomics, Inc. | Methods and apparatuses for stretching polymers |
WO2001093113A1 (en) * | 2000-03-28 | 2001-12-06 | Dana-Farber Cancer Institute, Inc. | Molecular database for antibody characterization |
AU2002318336A1 (en) * | 2001-06-08 | 2002-12-23 | U.S. Genomics, Inc. | Methods and products for analyzing nucleic acids based on methylation status |
CA2450479A1 (en) * | 2001-06-22 | 2003-01-03 | University Of Geneva | Method for detecting diseases caused by chromosomal imbalances |
US20030059822A1 (en) * | 2001-09-18 | 2003-03-27 | U.S. Genomics, Inc. | Differential tagging of polymers for high resolution linear analysis |
US7282330B2 (en) * | 2002-05-28 | 2007-10-16 | U.S. Genomics, Inc. | Methods and apparati using single polymer analysis |
JP2005527220A (ja) * | 2002-05-28 | 2005-09-15 | ユー.エス. ジェノミクス, インコーポレイテッド | 単一のポリマー分析を使用する方法および装置 |
US6952651B2 (en) * | 2002-06-17 | 2005-10-04 | Intel Corporation | Methods and apparatus for nucleic acid sequencing by signal stretching and data integration |
NL1021160C2 (nl) * | 2002-07-26 | 2004-01-27 | Multigen Internat B V | Werkwijze voor het bepalen van het kopieaantal van een nucleotidevolgorde. |
US7361821B2 (en) * | 2002-09-20 | 2008-04-22 | Intel Corporation | Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading |
JP4520857B2 (ja) * | 2002-09-20 | 2010-08-11 | インテル・コーポレーション | 走査型プローブ顕微鏡検査(spm)読取用の特定の情報をエンコードするナノバーコードの制御された整列 |
US7606403B2 (en) * | 2002-10-17 | 2009-10-20 | Intel Corporation | Model-based fusion of scanning probe microscopic images for detection and identification of molecular structures |
US7704687B2 (en) * | 2002-11-15 | 2010-04-27 | The Johns Hopkins University | Digital karyotyping |
US20050123944A1 (en) * | 2003-08-01 | 2005-06-09 | U.S. Genomics, Inc. | Methods and compositions related to the use of sequence-specific endonucleases for analyzing nucleic acids under non-cleaving conditions |
US20050064435A1 (en) * | 2003-09-24 | 2005-03-24 | Xing Su | Programmable molecular barcodes |
US20050147976A1 (en) * | 2003-12-29 | 2005-07-07 | Xing Su | Methods for determining nucleotide sequence information |
US20050151126A1 (en) * | 2003-12-31 | 2005-07-14 | Intel Corporation | Methods of producing carbon nanotubes using peptide or nucleic acid micropatterning |
WO2005089524A2 (en) * | 2004-03-19 | 2005-09-29 | U.S. Genomics, Inc. | Compositions and methods for detection of single molecules |
US7736818B2 (en) | 2004-12-27 | 2010-06-15 | Inphase Technologies, Inc. | Holographic recording medium and method of making it |
US8551760B2 (en) * | 2005-09-05 | 2013-10-08 | Shimadzu Corporation | Substrate for immobilizing biopolymer and method of immobilizing biopolymer by using the same |
WO2007076128A2 (en) * | 2005-12-23 | 2007-07-05 | Nanostring Technologies, Inc. | Nanoreporters and methods of manufacturing and use thereof |
ES2402939T3 (es) | 2005-12-23 | 2013-05-10 | Nanostring Technologies, Inc. | Composiciones que comprenden macromoléculas inmovilizadas y orientadas y métodos para su preparación |
US20100285993A1 (en) * | 2006-02-14 | 2010-11-11 | Gregory Prelich | Systematic Genomic Library and Uses Thereof |
EP2030011B1 (de) * | 2006-05-22 | 2017-02-01 | Nanostring Technologies, Inc. | Systeme und verfahren zur analyse von nanoreportern |
WO2008079169A2 (en) * | 2006-07-19 | 2008-07-03 | Bionanomatrix, Inc. | Nanonozzle device arrays: their preparation and use for macromolecular analysis |
JP5211790B2 (ja) * | 2007-03-26 | 2013-06-12 | 住友化学株式会社 | Dnaメチル化測定方法 |
KR101522741B1 (ko) * | 2007-03-28 | 2015-05-26 | 바이오나노 제노믹스, 인크. | 나노채널 어레이를 사용하는 거대분자 분석 방법 |
JP5555157B2 (ja) * | 2007-04-10 | 2014-07-23 | ナノストリング テクノロジーズ, インコーポレイテッド | ナノレポーターにおける使用のための標的特異的配列を同定するための方法およびコンピュータシステム |
JP5260981B2 (ja) * | 2008-02-22 | 2013-08-14 | 株式会社日立ハイテクノロジーズ | 真空処理装置 |
JP5730762B2 (ja) | 2008-06-30 | 2015-06-10 | バイオナノ ジェノミックス、インク. | 単一分子全ゲノム解析のための方法及び装置 |
JP2010068800A (ja) * | 2008-08-19 | 2010-04-02 | Sumitomo Chemical Co Ltd | Dnaを定量又は検出する方法 |
EP2175037B1 (de) | 2008-09-26 | 2017-10-11 | Genomic Vision | Verfahren zur Analyse von D4Z4-Tandemwiederholungsarrays von Nukleinsäure und Kit dafür |
CN108467887A (zh) | 2008-11-18 | 2018-08-31 | 生物纳米基因公司 | 多核苷酸作图和测序 |
US8709717B2 (en) | 2009-04-03 | 2014-04-29 | Illumina, Inc. | Generation of uniform fragments of nucleic acids using patterned substrates |
CN105734170A (zh) | 2010-04-23 | 2016-07-06 | 基因组影像公司 | 通过由分子梳检测基因组和感染性病毒dna的病毒感染的诊断 |
EP3078754A1 (de) | 2010-09-24 | 2016-10-12 | Genomic Vision | Verfahren für den nachweis, die quantifizierung und kartierung von schäden und/oder reparaturen von dna-strängen |
WO2012164401A1 (en) | 2011-06-03 | 2012-12-06 | Genomic Vision | Assessment of cancer risk based on rnu2 cnv and interplay between rnu2 cnv and brca1 |
WO2013064896A1 (en) * | 2011-10-31 | 2013-05-10 | Genomic Vision | Method for identifying or detecting genomic rearrangements in a biological sample |
US9028776B2 (en) | 2012-04-18 | 2015-05-12 | Toxic Report Llc | Device for stretching a polymer in a fluid sample |
US20140371088A1 (en) | 2013-06-14 | 2014-12-18 | Nanostring Technologies, Inc. | Multiplexable tag-based reporter system |
US20180135080A1 (en) | 2016-11-15 | 2018-05-17 | Genomic Vision Sa | Method for the monitoring of modified nucleases induced-gene editing events by molecular combing |
EP3548637A1 (de) | 2016-11-29 | 2019-10-09 | Genomic Vision | Verfahren zum entwurf eines satzes von polynukleotidsequenzen zur analyse von spezifischen ereignissen in einer genetischen region von interesse |
CN111566211A (zh) * | 2017-11-29 | 2020-08-21 | X基因组公司 | 新兴的核酸测序技术 |
CA3140900A1 (en) * | 2019-05-29 | 2020-12-03 | Xgenomes Corp. | Sequencing by emergence |
JP7456776B2 (ja) | 2020-01-16 | 2024-03-27 | 日清紡マイクロデバイス株式会社 | 炭化珪素半導体装置の製造方法 |
WO2021222512A1 (en) | 2020-04-30 | 2021-11-04 | Dimensiongen | Devices and methods for macromolecular manipulation |
EP4158064A1 (de) | 2020-06-01 | 2023-04-05 | Dimensiongen | Vorrichtungen und verfahren zur genomanalyse |
WO2022035729A1 (en) | 2020-08-10 | 2022-02-17 | Dimensiongen | Devices and methods for multi-dimensional genome analysis |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5079169A (en) * | 1990-05-22 | 1992-01-07 | The Regents Of The Stanford Leland Junior University | Method for optically manipulating polymer filaments |
JP3123249B2 (ja) * | 1991-09-10 | 2001-01-09 | 株式会社日立製作所 | Dna分子の長さ計測方法および計測装置 |
ATE205542T1 (de) * | 1992-03-04 | 2001-09-15 | Univ California | Vergleichende genomhybridisierung |
WO1994016104A1 (en) * | 1993-01-08 | 1994-07-21 | Ctrc Research Foundation | Color imaging system for use in molecular biology |
US5472842A (en) * | 1993-10-06 | 1995-12-05 | The Regents Of The University Of California | Detection of amplified or deleted chromosomal regions |
AU8102694A (en) | 1993-11-17 | 1995-06-06 | Id Biomedical Corporation | Cycling probe cleavage detection of nucleic acid sequences |
FR2716263B1 (fr) | 1994-02-11 | 1997-01-17 | Pasteur Institut | Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon. |
US5830645A (en) * | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
US5851769A (en) * | 1995-09-27 | 1998-12-22 | The Regents Of The University Of California | Quantitative DNA fiber mapping |
WO1997018326A1 (en) * | 1995-11-13 | 1997-05-22 | Institut Pasteur | Ultrahigh resolution comparative nucleic acid hybridization to combed dna fibers |
FR2755149B1 (fr) * | 1996-10-30 | 1999-01-15 | Pasteur Institut | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
-
1997
- 1997-03-13 FR FR9702999A patent/FR2755149B1/fr not_active Expired - Lifetime
- 1997-10-30 EP EP97912288A patent/EP0935674B1/de not_active Expired - Lifetime
- 1997-10-30 AU AU49533/97A patent/AU4953397A/en not_active Abandoned
- 1997-10-30 DE DE69733958T patent/DE69733958T2/de not_active Expired - Lifetime
- 1997-10-30 WO PCT/FR1997/001949 patent/WO1998018959A1/fr active IP Right Grant
- 1997-10-30 US US09/297,302 patent/US6344319B1/en not_active Expired - Lifetime
- 1997-10-30 ES ES97912288T patent/ES2247623T3/es not_active Expired - Lifetime
- 1997-10-30 DK DK97912288T patent/DK0935674T3/da active
- 1997-10-30 JP JP52013998A patent/JP4226078B2/ja not_active Expired - Lifetime
- 1997-10-30 AT AT97912288T patent/ATE301724T1/de active
-
2001
- 2001-08-03 US US09/921,302 patent/US20020048767A1/en not_active Abandoned
-
2003
- 2003-03-11 US US10/386,354 patent/US7368234B2/en not_active Expired - Fee Related
-
2007
- 2007-11-15 JP JP2007296974A patent/JP4223538B2/ja not_active Expired - Lifetime
- 2007-11-15 JP JP2007297006A patent/JP4223539B2/ja not_active Expired - Lifetime
-
2008
- 2008-03-18 US US12/076,408 patent/US7732143B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2755149B1 (fr) | 1999-01-15 |
US6344319B1 (en) | 2002-02-05 |
EP0935674A1 (de) | 1999-08-18 |
US20040033510A1 (en) | 2004-02-19 |
DK0935674T3 (da) | 2005-12-05 |
US20020048767A1 (en) | 2002-04-25 |
JP2008067716A (ja) | 2008-03-27 |
DE69733958T2 (de) | 2006-05-18 |
ES2247623T3 (es) | 2006-03-01 |
JP4223538B2 (ja) | 2009-02-12 |
EP0935674B1 (de) | 2005-08-10 |
WO1998018959A1 (fr) | 1998-05-07 |
US7368234B2 (en) | 2008-05-06 |
JP2008061651A (ja) | 2008-03-21 |
US20090123926A1 (en) | 2009-05-14 |
JP4223539B2 (ja) | 2009-02-12 |
FR2755149A1 (fr) | 1998-04-30 |
US7732143B2 (en) | 2010-06-08 |
ATE301724T1 (de) | 2005-08-15 |
AU4953397A (en) | 1998-05-22 |
JP2001507929A (ja) | 2001-06-19 |
JP4226078B2 (ja) | 2009-02-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |