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DE69409874D1 - 16-Gliederige Makrolid-Derivate und Verfahren zu deren Herstellung - Google Patents

16-Gliederige Makrolid-Derivate und Verfahren zu deren Herstellung

Info

Publication number
DE69409874D1
DE69409874D1 DE69409874T DE69409874T DE69409874D1 DE 69409874 D1 DE69409874 D1 DE 69409874D1 DE 69409874 T DE69409874 T DE 69409874T DE 69409874 T DE69409874 T DE 69409874T DE 69409874 D1 DE69409874 D1 DE 69409874D1
Authority
DE
Germany
Prior art keywords
hydrogen atom
macrolide derivatives
link
preparation
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69409874T
Other languages
English (en)
Other versions
DE69409874T2 (de
Inventor
Keiichi Ajito
Osamu Hara
Ken-Ichi Kurihara
Nobue Kikuchi
Minako Araake
Akira Shimizu
Tsuneo Okonogi
Shigeharu Inouye
Seiji Shibahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP16941893A external-priority patent/JP3023041B2/ja
Priority claimed from JP5300686A external-priority patent/JPH07149788A/ja
Priority claimed from JP6105096A external-priority patent/JPH07309889A/ja
Priority claimed from JP6126654A external-priority patent/JPH07330791A/ja
Priority claimed from JP6145125A external-priority patent/JPH0812696A/ja
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Application granted granted Critical
Publication of DE69409874D1 publication Critical patent/DE69409874D1/de
Publication of DE69409874T2 publication Critical patent/DE69409874T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69409874T 1993-07-08 1994-07-08 16-Gliederige Makrolid-Derivate und Verfahren zu deren Herstellung Expired - Fee Related DE69409874T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP16941893A JP3023041B2 (ja) 1993-07-08 1993-07-08 新規１６員環マクロリド誘導体
JP5300686A JPH07149788A (ja) 1993-11-30 1993-11-30 新規１６員環マクロリド誘導体及びそれらの効率的製造法
JP6105096A JPH07309889A (ja) 1994-05-19 1994-05-19 新規１６員環マクロリド誘導体及びそれらの新規製造法
JP6126654A JPH07330791A (ja) 1994-06-08 1994-06-08 新規１６員環マクロリド誘導体及びそれらの新規包括的製造法
JP6145125A JPH0812696A (ja) 1994-06-27 1994-06-27 新規１６員環マクロリド誘導体及びそれらの効率的製造法

Publications (2)

Publication Number Publication Date
DE69409874D1 true DE69409874D1 (de) 1998-06-04
DE69409874T2 DE69409874T2 (de) 1999-01-21

Family

ID=27526205

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69409874T Expired - Fee Related DE69409874T2 (de) 1993-07-08 1994-07-08 16-Gliederige Makrolid-Derivate und Verfahren zu deren Herstellung

Country Status (8)

Country Link
US (1) US5602106A (de)
EP (1) EP0633266B1 (de)
KR (1) KR100360568B1 (de)
CN (2) CN1046534C (de)
AT (1) ATE165604T1 (de)
CA (1) CA2127578A1 (de)
DE (1) DE69409874T2 (de)
ES (1) ES2115816T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4951400A (en) * 1999-06-01 2000-12-18 Meiji Seika Kaisha Ltd. 3-modified leucomycin derivatives
WO2007144876A1 (en) 2006-06-12 2007-12-21 Ramot At Tel-Aviv University Ltd. Methods for treating cancer
CN102344946B (zh) * 2010-08-02 2014-06-25 中牧实业股份有限公司 一种生物转化合成普拉特霉素a1的方法
AU2012211760A1 (en) * 2011-01-31 2013-08-15 Meiji Seika Pharma Co., Ltd. Novel macrolide derivative
MX2015008146A (es) 2012-12-24 2016-01-20 Univ Ramot Agentes para tratar enfermedades geneticas derivadas de mutaciones sin sentido y metodos para identificarlas.
JP6959355B2 (ja) * 2017-04-06 2021-11-02 沈陽福洋医薬科技有限公司Ｓｈｅｎｙａｎｇ Ｆｕｙａｎｇ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏ．， Ｌｔｄ 腫瘍を治療および／または予防する薬物の調製におけるカリマイシンおよびその薬学的に許容可能な塩の応用
EP3639829B1 (de) * 2017-07-04 2022-02-09 Shenyang Fuyang Pharmaceutical Technology Co., Ltd. Verwendung von isovalerylspiramycin i oder iii zur herstellung eines arzneimittels zur behandlung und/oder vorbeugung von tumoren und arzneimittel

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2638458A1 (fr) * 1988-10-27 1990-05-04 Adir Nouveaux derives de la tylosine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP3063943B2 (ja) * 1992-02-26 2000-07-12 明治製菓株式会社 血漿中において抗菌活性の持続する新規１６員環マクロリド誘導体及びその合成中間体とそれらの製造法
ES2131549T3 (es) * 1992-10-29 1999-08-01 Meiji Seika Kaisha Derivados macrolidas de 16 eslabones y su procedimiento de preparacion.

Also Published As

Publication number Publication date
EP0633266B1 (de) 1998-04-29
CN1046534C (zh) 1999-11-17
CN1219539A (zh) 1999-06-16
DE69409874T2 (de) 1999-01-21
ES2115816T3 (es) 1998-07-01
CA2127578A1 (en) 1995-01-09
CN1093134C (zh) 2002-10-23
KR100360568B1 (en) 2003-03-12
ATE165604T1 (de) 1998-05-15
US5602106A (en) 1997-02-11
CN1106818A (zh) 1995-08-16
EP0633266A1 (de) 1995-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee