DE68906647D1 - Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel. - Google Patents

Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel.

Info

Publication number: DE68906647D1
Authority: DE; Germany
Prior art keywords: hydroxy; loweralkyl; hydrogen; tetrahydroaminoacridine; production
Prior art date: 1988-11-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE8989121037T

Other languages

English (en)

Other versions

DE68906647T2 (de

Inventor

Gregory Michael Shutske

John Dick Tomer Iv

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aventis Pharmaceuticals Inc

Original Assignee

Hoechst Roussel Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-11-16

Filing date

1989-11-14

Publication date

1993-06-24

1989-11-14 Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc

1993-06-24 Publication of DE68906647D1 publication Critical patent/DE68906647D1/de

1993-10-07 Application granted granted Critical

1993-10-07 Publication of DE68906647T2 publication Critical patent/DE68906647T2/de

2009-11-15 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
- C07D219/12—Amino-alkylamino radicals attached in position 9

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Saccharide Compounds (AREA)

DE89121037T 1988-11-16 1989-11-14 Hydroxy-1,2,3,4-tetrahydroaminoacridine, Verfahren für ihre Herstellung und ihre Verwendung als Arzneimittel. Expired - Fee Related DE68906647T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US27178888A	1988-11-16	1988-11-16

Publications (2)

Publication Number	Publication Date
DE68906647D1 true DE68906647D1 (de)	1993-06-24
DE68906647T2 DE68906647T2 (de)	1993-10-07

Family

ID=23037088

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE89121037T Expired - Fee Related DE68906647T2 (de)	1988-11-16	1989-11-14	Hydroxy-1,2,3,4-tetrahydroaminoacridine, Verfahren für ihre Herstellung und ihre Verwendung als Arzneimittel.

Country Status (15)

Country	Link
EP (1)	EP0369388B1 (de)
KR (1)	KR0156241B1 (de)
AT (1)	ATE89553T1 (de)
CA (1)	CA2003023C (de)
DE (1)	DE68906647T2 (de)
DK (1)	DK168290B1 (de)
ES (1)	ES2054987T3 (de)
FI (1)	FI90417C (de)
HU (2)	HU208674B (de)
IE (1)	IE63038B1 (de)
IL (1)	IL92307A0 (de)
NO (1)	NO894547L (de)
NZ (1)	NZ231376A (de)
PT (1)	PT92319B (de)
ZA (1)	ZA898720B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200462B (de) *	1990-09-27	1993-02-21	Hoechst Roussel Pharma
GB2264707A (en) *	1991-06-18	1993-09-08	Roger Michael Marchbanks	Acridine derivatives for treating alzheimer's disease
US5422350A (en) *	1992-09-10	1995-06-06	Warner-Lambert Company	Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
US5466696A (en) *	1992-09-10	1995-11-14	Warner Lambert Company	Tacrine and cytochrome P450 oxidase inhibitors and methods of use
WO2019207604A1 (en) *	2018-04-25	2019-10-31	Rajiv Gandhi Centre For Biotechnology	Tacrine derivatives targeting nmda receptor, acetylcholine esterase, butyryl choline and beta secretase activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0179383B1 (de) *	1984-10-25	1991-05-29	Hoechst-Roussel Pharmaceuticals Incorporated	9-Amino-1,2,3,4-tetrahydroacridin-1-ol und verwandte Verbindungen, Verfahren zu ihrer Herstellung und Verwendung als Arzneimittel
IL85741A (en) *	1987-03-17	1996-05-14	Hoechst Roussel Pharma	Transformed Tetra-Hydroacridines Process for their preparation and pharmaceutical preparations containing A-amino-Tetra-Transformed Hydroacridines

1989
- 1989-11-14 NZ NZ231376A patent/NZ231376A/en unknown
- 1989-11-14 FI FI895416A patent/FI90417C/fi not_active IP Right Cessation
- 1989-11-14 AT AT89121037T patent/ATE89553T1/de not_active IP Right Cessation
- 1989-11-14 EP EP89121037A patent/EP0369388B1/de not_active Expired - Lifetime
- 1989-11-14 ES ES89121037T patent/ES2054987T3/es not_active Expired - Lifetime
- 1989-11-14 IL IL92307A patent/IL92307A0/xx unknown
- 1989-11-14 KR KR1019890016456A patent/KR0156241B1/ko not_active IP Right Cessation
- 1989-11-14 DE DE89121037T patent/DE68906647T2/de not_active Expired - Fee Related
- 1989-11-15 DK DK571989A patent/DK168290B1/da not_active IP Right Cessation
- 1989-11-15 ZA ZA898720A patent/ZA898720B/xx unknown
- 1989-11-15 NO NO89894547A patent/NO894547L/no unknown
- 1989-11-15 IE IE365989A patent/IE63038B1/en not_active IP Right Cessation
- 1989-11-15 PT PT92319A patent/PT92319B/pt active IP Right Grant
- 1989-11-15 CA CA002003023A patent/CA2003023C/en not_active Expired - Fee Related
- 1989-11-16 HU HU593189A patent/HU208674B/hu unknown
1995
- 1995-06-22 HU HU95P/P00336P patent/HU211701A9/hu unknown

Also Published As

Publication number	Publication date
DE68906647T2 (de)	1993-10-07
EP0369388A1 (de)	1990-05-23
FI90417C (fi)	1994-02-10
IE893659L (en)	1990-05-16
NZ231376A (en)	1992-05-26
NO894547L (no)	1990-05-18
HU208674B (en)	1993-12-28
HU895931D0 (en)	1990-02-28
FI895416A0 (fi)	1989-11-14
IE63038B1 (en)	1995-03-22
KR0156241B1 (ko)	1998-11-16
DK168290B1 (da)	1994-03-07
DK571989A (da)	1990-05-17
ZA898720B (en)	1990-08-29
KR900007809A (ko)	1990-06-02
IL92307A0 (en)	1990-07-26
FI90417B (fi)	1993-10-29
NO894547D0 (no)	1989-11-15
HUT53087A (en)	1990-09-28
DK571989D0 (da)	1989-11-15
CA2003023C (en)	2001-05-29
HU211701A9 (en)	1995-12-28
ES2054987T3 (es)	1994-08-16
ATE89553T1 (de)	1993-06-15
PT92319B (pt)	1995-08-09
CA2003023A1 (en)	1990-05-16
EP0369388B1 (de)	1993-05-19
PT92319A (pt)	1990-05-31

Publication	Publication Date	Title
DE3772905D1 (de)	1991-10-17	Alpha-alkyl-4-amino-3-chinolin-methanole und 1-(4-aralkylamino-3-chinolyl)alkanone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE69031259D1 (de)	1997-09-18	Mit Physostigmine verwandte N-aminocarbamate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE68906647D1 (de)	1993-06-24	Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel.
ATE111899T1 (de)	1994-10-15	1,2,3,4-tetrahydro-1,9-acridindiamine, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente.
ATE79118T1 (de)	1992-08-15	N-pyridinyl-9h-carbazol-9-amine, verfahren zu ihrer herstellung und ihre verwendung als medikamente.
ATE104298T1 (de)	1994-04-15	Kondensierte heterocyclische derivate von 1,2,3,4-tetrahydroacridin, verfahren zu ihrer herstellung und ihre verwendung als medikament.
HU9402434D0 (en)	1994-10-28	Process for producing 2,3,4,5-tetrahydro-1h-3-benzodiazepines and pharmaceutically acceptable acid additional salts thereof
ATE122047T1 (de)	1995-05-15	4,5,5a,6-tetrahydro-3h-isoxyzolo(5,4,3- k1)acridinderivate, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente.
MX25922A (es)	1993-10-01	Pirido (3,4-b) pirrolo (1,2-e)(1,4,5)oxadiazepinasy compuestos analogos relacionados un procedimiento para su preparacion y su uso como medicamentos
ATE173734T1 (de)	1998-12-15	Heteroarenylpiperazine, verfahren zu ihrer herstellung und ihre anwendung als medikamente
EP0258048A3 (en)	1988-11-09	2-amino-3-aroyl-gamma-oxobenzenebutanoic acids and esters

Legal Events

Date	Code	Title	Description
1994-06-16	8364	No opposition during term of opposition
2004-09-23	8339	Ceased/non-payment of the annual fee