DE60238856D1 - Anthranilsäureamide und ihre pharmazeutische verwendung - Google Patents

Anthranilsäureamide und ihre pharmazeutische verwendung

Info

Publication number: DE60238856D1
Authority: DE; Germany
Prior art keywords: acid amide; pharmaceutical use; anthranilic acid; anthranilic; pharmaceutical
Prior art date: 2001-11-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60238856T

Other languages

English (en)

Inventor

Guido Bold

Pascal Furet

Paul William Manley

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee

Novartis AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-08

Filing date

2002-11-07

Publication date

2011-02-17

2002-11-07 Application filed by Novartis AG filed Critical Novartis AG

2011-02-17 Application granted granted Critical

2011-02-17 Publication of DE60238856D1 publication Critical patent/DE60238856D1/de

2022-11-08 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/40—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Indole Compounds (AREA)

DE60238856T 2001-11-08 2002-11-07 Anthranilsäureamide und ihre pharmazeutische verwendung Expired - Lifetime DE60238856D1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB0126901.8A GB0126901D0 (en)	2001-11-08	2001-11-08	Organic compounds
GBGB0212917.9A GB0212917D0 (en)	2001-11-08	2002-06-05	Organic compounds
PCT/EP2002/012445 WO2003040101A1 (en)	2001-11-08	2002-11-07	Anthranilic acid amides and pharmaceutical use thereof

Publications (1)

Publication Number	Publication Date
DE60238856D1 true DE60238856D1 (de)	2011-02-17

Family

ID=26246753

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60238856T Expired - Lifetime DE60238856D1 (de)	2001-11-08	2002-11-07	Anthranilsäureamide und ihre pharmazeutische verwendung

Country Status (25)

Country	Link
US (1)	US7067543B2 (de)
EP (2)	EP1446381B1 (de)
JP (1)	JP4179989B2 (de)
KR (1)	KR100633814B1 (de)
CN (1)	CN100467450C (de)
AR (1)	AR037261A1 (de)
AT (1)	ATE494278T1 (de)
AU (1)	AU2002342889B2 (de)
BR (1)	BR0213939A (de)
CA (1)	CA2462390C (de)
DE (1)	DE60238856D1 (de)
GB (2)	GB0126901D0 (de)
HR (1)	HRP20040412A2 (de)
IL (1)	IL161163A0 (de)
MX (1)	MXPA04004390A (de)
MY (1)	MY136322A (de)
NO (1)	NO326986B1 (de)
NZ (1)	NZ532587A (de)
PE (1)	PE20030540A1 (de)
PL (1)	PL368417A1 (de)
PT (1)	PT1446381E (de)
RS (1)	RS29404A (de)
RU (1)	RU2315756C2 (de)
TW (1)	TWI260985B (de)
WO (1)	WO2003040101A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7307088B2 (en)	2002-07-09	2007-12-11	Amgen Inc.	Substituted anthranilic amide derivatives and methods of use
GB0229022D0 (en) *	2002-12-12	2003-01-15	Novartis Ag	Organic Compounds
UA89035C2 (ru)	2003-12-03	2009-12-25	Лео Фарма А/С	Эфиры гидроксамовых кислот и их фармацевтическое применение
BR122015027139B1 (pt)	2004-01-28	2016-05-10	Mitsui Chemicals Inc	compostos derivados de amida, inseticida compreendendo os mesmos e método de uso dos mesmos como inseticida
DE102004009238A1 (de) *	2004-02-26	2005-09-08	Merck Patent Gmbh	Arylamid-Derivate
JPWO2006070878A1 (ja) *	2004-12-28	2008-06-12	アステラス製薬株式会社	カルボン酸誘導体またはその塩
EP2145873A1 (de) *	2008-06-17	2010-01-20	Commissariat A L'energie Atomique	Neue Verbindungen, die eine Schutzaktivität gegen die Wirkung von Toxinen und Viren über einen intrazellulären Wirkungsmechanismus entfalten
PL2346827T3 (pl)	2008-08-27	2014-04-30	Leo Pharma As	Pochodne pirydyny jako inhibitory receptora VEGFR-2 i białkowej kinazy tyrozynowej
JP2011057661A (ja) *	2009-08-14	2011-03-24	Bayer Cropscience Ag	殺虫性カルボキサミド類

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3226394A (en) *	1964-06-16	1965-12-28	Shulton Inc	Pyridylethylated anthranilamides and derivatives thereof
WO1998014449A1 (en)	1996-10-02	1998-04-09	Novartis Ag	Fused pyrazole derivatives and processes for their preparation
GB9824579D0 (en)	1998-11-10	1999-01-06	Novartis Ag	Organic compounds

2001
- 2001-11-08 GB GBGB0126901.8A patent/GB0126901D0/en not_active Ceased
2002
- 2002-06-05 GB GBGB0212917.9A patent/GB0212917D0/en not_active Ceased
- 2002-11-06 TW TW091132668A patent/TWI260985B/zh active
- 2002-11-06 PE PE2002001081A patent/PE20030540A1/es not_active Application Discontinuation
- 2002-11-06 AR ARP020104236A patent/AR037261A1/es not_active Application Discontinuation
- 2002-11-07 CN CNB028214307A patent/CN100467450C/zh not_active Expired - Fee Related
- 2002-11-07 MY MYPI20024160A patent/MY136322A/en unknown
- 2002-11-07 AT AT02779536T patent/ATE494278T1/de active
- 2002-11-07 US US10/494,222 patent/US7067543B2/en not_active Expired - Fee Related
- 2002-11-07 JP JP2003542147A patent/JP4179989B2/ja not_active Expired - Fee Related
- 2002-11-07 NZ NZ532587A patent/NZ532587A/en not_active IP Right Cessation
- 2002-11-07 EP EP02779536A patent/EP1446381B1/de not_active Expired - Lifetime
- 2002-11-07 PT PT02779536T patent/PT1446381E/pt unknown
- 2002-11-07 EP EP10180423A patent/EP2269988B1/de not_active Expired - Lifetime
- 2002-11-07 RS YUP-294/04A patent/RS29404A/sr unknown
- 2002-11-07 PL PL02368417A patent/PL368417A1/xx not_active Application Discontinuation
- 2002-11-07 MX MXPA04004390A patent/MXPA04004390A/es active IP Right Grant
- 2002-11-07 BR BR0213939-1A patent/BR0213939A/pt not_active IP Right Cessation
- 2002-11-07 RU RU2004117548/04A patent/RU2315756C2/ru not_active IP Right Cessation
- 2002-11-07 KR KR1020047007000A patent/KR100633814B1/ko not_active IP Right Cessation
- 2002-11-07 DE DE60238856T patent/DE60238856D1/de not_active Expired - Lifetime
- 2002-11-07 WO PCT/EP2002/012445 patent/WO2003040101A1/en active IP Right Grant
- 2002-11-07 AU AU2002342889A patent/AU2002342889B2/en not_active Ceased
- 2002-11-07 IL IL16116302A patent/IL161163A0/xx unknown
- 2002-11-07 CA CA2462390A patent/CA2462390C/en not_active Expired - Fee Related
2004
- 2004-05-07 HR HR20040412A patent/HRP20040412A2/hr not_active Application Discontinuation
- 2004-05-25 NO NO20042137A patent/NO326986B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU2002342889B2 (en)	2007-03-01
GB0212917D0 (en)	2002-07-17
MY136322A (en)	2008-09-30
US7067543B2 (en)	2006-06-27
KR100633814B1 (ko)	2006-10-13
PE20030540A1 (es)	2003-08-05
NZ532587A (en)	2006-02-24
JP4179989B2 (ja)	2008-11-12
AR037261A1 (es)	2004-11-03
KR20050044374A (ko)	2005-05-12
CN1578768A (zh)	2005-02-09
RS29404A (en)	2007-02-05
NO326986B1 (no)	2009-03-30
ATE494278T1 (de)	2011-01-15
US20040248947A1 (en)	2004-12-09
WO2003040101A1 (en)	2003-05-15
BR0213939A (pt)	2004-08-31
CA2462390A1 (en)	2003-05-15
EP2269988A3 (de)	2011-02-16
PT1446381E (pt)	2011-01-31
CA2462390C (en)	2011-01-11
EP1446381B1 (de)	2011-01-05
IL161163A0 (en)	2004-08-31
PL368417A1 (en)	2005-03-21
GB0126901D0 (en)	2002-01-02
CN100467450C (zh)	2009-03-11
EP1446381A1 (de)	2004-08-18
TWI260985B (en)	2006-09-01
MXPA04004390A (es)	2005-05-16
RU2315756C2 (ru)	2008-01-27
HRP20040412A2 (en)	2005-06-30
NO20042137L (no)	2004-05-25
RU2004117548A (ru)	2005-06-10
EP2269988B1 (de)	2012-05-23
TW200300086A (en)	2003-05-16
JP2005508382A (ja)	2005-03-31
EP2269988A2 (de)	2011-01-05

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ATE279438T1 (de)	2004-10-15	Entzündungshemmende verbindungen und ihre verwendung
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HUP0302845A3 (en)	2005-11-28	4-fluoro-n-indan-2-yl benzamide and its use as pharmaceutical
EE200300311A (et)	2003-10-15	Ftalasinoon-piperidinoderivaadid, nende kasutamine ja ravim
ATE419366T1 (de)	2009-01-15	Tyra-gene und ihre verwendung
DE60230883D1 (de)	2009-03-05	Neue formulierungen und ihre verwendung
DE50206094D1 (de)	2006-05-11	Substituierte isoindole und ihre verwendung
DE60217089D1 (de)	2007-02-08	Lipidsenkende biphenylcarbonsäureamide
DE60230162D1 (de)	2009-01-15	Polymerisate und ihre verwendung
DE60238856D1 (de)	2011-02-17	Anthranilsäureamide und ihre pharmazeutische verwendung
DE50202730D1 (de)	2005-05-12	Substituierte isoindole und ihre verwendung
AU2002342889A1 (en)	2003-07-24	Anthranilic acid amides and pharmaceutical use thereof
DE602004022169D1 (de)	2009-09-03	Tetrahydrocarbazolderivate und deren pharmazeutische verwendung
NO20054662D0 (no)	2005-10-11	Farmasoytisk sammensetning omfattende 5-metyl-2-2'-(klor-6'-fluoranilin)fenyleddiksyre
DE60222252D1 (de)	2007-10-18	Acrylester und ihre verwendung

Legal Events

Date	Code	Title	Description
2011-06-16	8328	Change in the person/name/address of the agent	Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN