DE602005007874D1 - Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden - Google Patents
Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotidenInfo
- Publication number
- DE602005007874D1 DE602005007874D1 DE602005007874T DE602005007874T DE602005007874D1 DE 602005007874 D1 DE602005007874 D1 DE 602005007874D1 DE 602005007874 T DE602005007874 T DE 602005007874T DE 602005007874 T DE602005007874 T DE 602005007874T DE 602005007874 D1 DE602005007874 D1 DE 602005007874D1
- Authority
- DE
- Germany
- Prior art keywords
- present
- encoding
- reaction
- decoding
- coding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000006243 chemical reaction Methods 0.000 title abstract 5
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000000523 sample Substances 0.000 abstract 4
- 230000003321 amplification Effects 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55615704P | 2004-03-24 | 2004-03-24 | |
US55622404P | 2004-03-24 | 2004-03-24 | |
US55616304P | 2004-03-24 | 2004-03-24 | |
US55616204P | 2004-03-24 | 2004-03-24 | |
US63068104P | 2004-11-24 | 2004-11-24 | |
PCT/US2005/009882 WO2005094532A2 (en) | 2004-03-24 | 2005-03-24 | Encoding and decoding reactions for determining target polynucleotides |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005007874D1 true DE602005007874D1 (de) | 2008-08-14 |
Family
ID=35064420
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005014453T Active DE602005014453D1 (de) | 2004-03-24 | 2005-03-24 | Ligation und amplifikationsreaktionen zur bestimmung von zielmolekülen |
DE602005007874T Active DE602005007874D1 (de) | 2004-03-24 | 2005-03-24 | Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005014453T Active DE602005014453D1 (de) | 2004-03-24 | 2005-03-24 | Ligation und amplifikationsreaktionen zur bestimmung von zielmolekülen |
Country Status (6)
Country | Link |
---|---|
US (2) | US7601821B2 (de) |
EP (3) | EP2161346B1 (de) |
JP (2) | JP2007530051A (de) |
AT (2) | ATE399884T1 (de) |
DE (2) | DE602005014453D1 (de) |
WO (2) | WO2005094532A2 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7153658B2 (en) * | 2002-09-19 | 2006-12-26 | Applera Corporation | Methods and compositions for detecting targets |
US7570443B2 (en) | 2003-09-19 | 2009-08-04 | Applied Biosystems, Llc | Optical camera alignment |
WO2005094532A2 (en) | 2004-03-24 | 2005-10-13 | Applera Corporation | Encoding and decoding reactions for determining target polynucleotides |
WO2006076017A2 (en) * | 2004-04-30 | 2006-07-20 | Applera Corporation | Methods and kits for identifying target nucleotides in mixed populations |
US7364855B2 (en) * | 2004-04-30 | 2008-04-29 | Applera Corporation | Methods and kits for methylation detection |
US7575863B2 (en) * | 2004-05-28 | 2009-08-18 | Applied Biosystems, Llc | Methods, compositions, and kits comprising linker probes for quantifying polynucleotides |
US20060019288A1 (en) * | 2004-06-30 | 2006-01-26 | Applera Corporation | Methods, reaction mixtures, and kits for ligating polynucleotides |
US7642055B2 (en) * | 2004-09-21 | 2010-01-05 | Applied Biosystems, Llc | Two-color real-time/end-point quantitation of microRNAs (miRNAs) |
CN101351542A (zh) * | 2005-07-15 | 2009-01-21 | 阿普尔拉公司 | 液体加工装置和方法 |
WO2007011903A2 (en) | 2005-07-15 | 2007-01-25 | Applera Corporation | Analyzing messenger rna and micro rna in the same reaction mixture |
WO2007024800A2 (en) * | 2005-08-22 | 2007-03-01 | Applera Corporation | Device and method for making discrete volumes of a first fluid in contact with a second fluid, which are immiscible with each other |
EP1924713B1 (de) * | 2005-08-24 | 2011-11-09 | Life Technologies Corporation | Verfahren zur quantifizierung von sirnas, mirnas und polymorphen mirnas |
JP2009536525A (ja) * | 2006-05-10 | 2009-10-15 | ディクステリティー ダイアグノーティクス | 化学反応性オリゴヌクレオチドプローブを使用した核酸標的の検出 |
US8597938B2 (en) * | 2007-10-12 | 2013-12-03 | Qiagen Sciences Llc | System for providing control reactions for real time RT-PCR |
WO2009100449A1 (en) * | 2008-02-08 | 2009-08-13 | Fluidigm Corporation | Dynamic array assay methods |
WO2010027870A2 (en) * | 2008-08-26 | 2010-03-11 | Fluidigm Corporation | Assay methods for increased throughput of samples and/or targets |
EP3216874A1 (de) | 2008-09-05 | 2017-09-13 | TOMA Biosciences, Inc. | Verfahren zum stratifizieren und annotieren der behandlungsoptionen eines krebsmedikaments |
JP5608998B2 (ja) * | 2009-03-31 | 2014-10-22 | 東洋紡株式会社 | 保存安定性に優れた核酸増幅検出試薬キット |
EP2414544B1 (de) * | 2009-04-01 | 2014-04-23 | DXTerity Diagnostics Incorporated | Chemische ligationsabhängige sondenamplifizierung (clpa) |
CN103952482A (zh) * | 2009-04-02 | 2014-07-30 | 弗卢伊蒂格姆公司 | 用于对目标核酸进行条形码化的多引物扩增方法 |
EP2464755B1 (de) | 2009-11-05 | 2016-03-09 | Epicentre Technologies Corporation | Verfahren und kits zur 3'-enden-markierung von rna |
CN102648295B (zh) * | 2009-12-07 | 2017-08-08 | 伊鲁米那股份有限公司 | 用于多重基因分型的多样品索引 |
WO2011100057A2 (en) * | 2010-02-09 | 2011-08-18 | Eugene Spier | Methods and compositions for universal detection of nucleic acids |
EP3572528A1 (de) | 2010-09-24 | 2019-11-27 | The Board of Trustees of the Leland Stanford Junior University | Direkte erfassung, amplifikation und sequenzierung einer ziel-dna unter verwendung immobilisierter primer |
WO2012054933A2 (en) * | 2010-10-22 | 2012-04-26 | Fluidigm Corporation | Universal probe assay methods |
US20120288857A1 (en) * | 2011-02-03 | 2012-11-15 | Fluidigm Corporation | Multifunctional probe-primers |
WO2012142003A2 (en) | 2011-04-15 | 2012-10-18 | Life Technologies Corporation | Chemical ligation |
CN108342453A (zh) | 2011-05-09 | 2018-07-31 | 富鲁达公司 | 基于探针的核酸检测 |
US9745616B2 (en) | 2011-05-17 | 2017-08-29 | Dxterity Diagnostics Incorporated | Methods and compositions for detecting target nucleic acids |
CN112592960B (zh) | 2011-05-20 | 2024-08-27 | 富鲁达公司 | 核酸编码反应 |
US20140242587A1 (en) * | 2011-10-03 | 2014-08-28 | University Of Florida Research Foundation, Inc. | Rapid and Reliable Detection of Infectious Agents |
CN104487097B (zh) | 2011-12-30 | 2019-01-18 | 华盛顿大学商业中心 | 具有窄带发射的发色聚合物点 |
WO2013106807A1 (en) | 2012-01-13 | 2013-07-18 | Curry John D | Scalable characterization of nucleic acids by parallel sequencing |
EP4361609A3 (de) | 2012-02-03 | 2024-07-17 | California Institute of Technology | Signalkodierung und -dekodierung in multiplexierten biochemischen assays |
SG11201404899VA (en) | 2012-02-14 | 2014-10-30 | Univ Cornell | Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions |
JP2015519900A (ja) | 2012-05-21 | 2015-07-16 | フリューダイム・コーポレイション | 粒子集団の単粒子解析方法及び単粒子単離方法 |
EP3901243A1 (de) | 2012-08-03 | 2021-10-27 | California Institute of Technology | Multiplexing und quantifizierung in pcr mit reduzierter hardware und reduzierten anforderungen |
EP2971172B1 (de) | 2013-03-14 | 2019-07-24 | Cornell University | Verfahren zur relativen quantifizierung von veränderungen in einer dna-methylierung mit kombinierten nuklease-, ligations- und polymerasereaktionen |
WO2015153571A2 (en) | 2014-04-01 | 2015-10-08 | Cornell University | Detection of dna methylation using combined nuclease ligation reactions |
EP3154696B1 (de) | 2014-06-10 | 2020-04-08 | DxTerity Diagnostics Incorporated | Vorrichtungen und verfahren zur entnahme und stabilisierung biologischer proben |
CN107002145B (zh) | 2014-10-08 | 2021-07-30 | 康奈尔大学 | 一种用于鉴定样品中的含有靶核苷酸序列的一个或多个核酸分子的方法 |
WO2017044993A2 (en) * | 2015-09-08 | 2017-03-16 | Affymetrix, Inc. | Nucleic acid analysis by joining barcoded polynucleotide probes |
US11118216B2 (en) | 2015-09-08 | 2021-09-14 | Affymetrix, Inc. | Nucleic acid analysis by joining barcoded polynucleotide probes |
US11117113B2 (en) | 2015-12-16 | 2021-09-14 | Fluidigm Corporation | High-level multiplex amplification |
WO2017218777A1 (en) | 2016-06-17 | 2017-12-21 | California Institute Of Technology | Nucleic acid reactions and related methods and compositions |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
US5494810A (en) | 1990-05-03 | 1996-02-27 | Cornell Research Foundation, Inc. | Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease |
DK51092D0 (da) | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
WO1993020236A1 (en) | 1992-04-03 | 1993-10-14 | Applied Biosystems, Inc. | Probe composition and method |
WO1996015271A1 (en) | 1994-11-16 | 1996-05-23 | Abbott Laboratories | Multiplex ligations-dependent amplification |
GB9609441D0 (en) | 1996-05-04 | 1996-07-10 | Zeneca Ltd | Process |
WO1997045559A1 (en) | 1996-05-29 | 1997-12-04 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions |
US7014994B1 (en) * | 1999-03-19 | 2006-03-21 | Cornell Research Foundation,Inc. | Coupled polymerase chain reaction-restriction-endonuclease digestion-ligase detection reaction process |
US6331393B1 (en) | 1999-05-14 | 2001-12-18 | University Of Southern California | Process for high-throughput DNA methylation analysis |
EP1257664A4 (de) | 2000-01-28 | 2006-04-05 | Althea Technologies Inc | Verfahren zur analyse der genexpression |
CA2410950A1 (en) * | 2000-05-30 | 2001-12-06 | Hans-Michael Wenz | Methods for detecting target nucleic acids using coupled ligation and amplification |
US6620586B2 (en) | 2001-02-20 | 2003-09-16 | Applied Gene Technologies, Inc. | Methods and compositions for analyzing nucleic acids |
US20030119004A1 (en) * | 2001-12-05 | 2003-06-26 | Wenz H. Michael | Methods for quantitating nucleic acids using coupled ligation and amplification |
EP1319718A1 (de) | 2001-12-14 | 2003-06-18 | Keygene N.V. | Hochdurchsatzanalyse und Detektion von mehreren Zielsequenzen |
WO2003060163A2 (en) * | 2001-12-28 | 2003-07-24 | Keygene N.V. | Discrimination and detection of target nucleotide sequences using mass spectrometry |
US6960436B2 (en) * | 2002-02-06 | 2005-11-01 | Epigenomics Ag | Quantitative methylation detection in DNA samples |
US7176002B2 (en) * | 2002-05-16 | 2007-02-13 | Applera Corporation | Universal-tagged oligonucleotide primers and methods of use |
US7153658B2 (en) | 2002-09-19 | 2006-12-26 | Applera Corporation | Methods and compositions for detecting targets |
JP2006500033A (ja) | 2002-09-19 | 2006-01-05 | アプレラ コーポレイション | 標的を検出するための方法および組成物 |
US20040235005A1 (en) | 2002-10-23 | 2004-11-25 | Ernest Friedlander | Methods and composition for detecting targets |
US20040110134A1 (en) | 2002-12-05 | 2004-06-10 | Wenz H. Michael | Methods for quantitating nucleic acids using coupled ligation and amplification |
WO2005026389A2 (en) | 2003-08-29 | 2005-03-24 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Ligation-based method of analysis of single nucleotide polymorphisms on genomic dna |
WO2005094532A2 (en) | 2004-03-24 | 2005-10-13 | Applera Corporation | Encoding and decoding reactions for determining target polynucleotides |
-
2005
- 2005-03-24 WO PCT/US2005/009882 patent/WO2005094532A2/en active Search and Examination
- 2005-03-24 JP JP2007505241A patent/JP2007530051A/ja active Pending
- 2005-03-24 AT AT05732398T patent/ATE399884T1/de not_active IP Right Cessation
- 2005-03-24 US US11/090,830 patent/US7601821B2/en not_active Expired - Fee Related
- 2005-03-24 DE DE602005014453T patent/DE602005014453D1/de active Active
- 2005-03-24 AT AT05760637T patent/ATE431433T1/de not_active IP Right Cessation
- 2005-03-24 EP EP09004414.0A patent/EP2161346B1/de not_active Not-in-force
- 2005-03-24 EP EP05760637A patent/EP1727913B8/de not_active Not-in-force
- 2005-03-24 US US11/090,468 patent/US7604937B2/en not_active Expired - Fee Related
- 2005-03-24 WO PCT/US2005/010184 patent/WO2005098040A2/en not_active Application Discontinuation
- 2005-03-24 DE DE602005007874T patent/DE602005007874D1/de active Active
- 2005-03-24 EP EP05732398A patent/EP1730312B1/de not_active Not-in-force
- 2005-03-24 JP JP2007505187A patent/JP2007530048A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1727913B1 (de) | 2009-05-13 |
WO2005098040A3 (en) | 2006-03-23 |
EP2161346B1 (de) | 2013-06-19 |
ATE431433T1 (de) | 2009-05-15 |
EP1727913B8 (de) | 2009-08-19 |
JP2007530051A (ja) | 2007-11-01 |
WO2005094532A3 (en) | 2005-12-22 |
WO2005098040A2 (en) | 2005-10-20 |
EP1730312A2 (de) | 2006-12-13 |
WO2005094532A2 (en) | 2005-10-13 |
US7604937B2 (en) | 2009-10-20 |
WO2005098040A8 (en) | 2005-12-01 |
US7601821B2 (en) | 2009-10-13 |
EP2161346A1 (de) | 2010-03-10 |
JP2007530048A (ja) | 2007-11-01 |
EP1727913A2 (de) | 2006-12-06 |
US20050260640A1 (en) | 2005-11-24 |
EP1730312B1 (de) | 2008-07-02 |
DE602005014453D1 (de) | 2009-06-25 |
ATE399884T1 (de) | 2008-07-15 |
US20050272071A1 (en) | 2005-12-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US |
|
8380 | Miscellaneous part iii |
Free format text: PFANDRECHT |
|
8380 | Miscellaneous part iii |
Free format text: PFANDRECHT AUFGEHOBEN |