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DE60105243D1 - Oral anzuwendende tramadolhaltige Teilchen zur einmal täglichen Verabreichung - Google Patents

Oral anzuwendende tramadolhaltige Teilchen zur einmal täglichen Verabreichung

Info

Publication number
DE60105243D1
DE60105243D1 DE60105243T DE60105243T DE60105243D1 DE 60105243 D1 DE60105243 D1 DE 60105243D1 DE 60105243 T DE60105243 T DE 60105243T DE 60105243 T DE60105243 T DE 60105243T DE 60105243 D1 DE60105243 D1 DE 60105243D1
Authority
DE
Germany
Prior art keywords
once daily
containing particles
daily administration
tramadol
oral tramadol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60105243T
Other languages
English (en)
Other versions
DE60105243T2 (de
Inventor
Francis Vanderbist
Antonio Sereno
Philippe Baudier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SMB TECHNOLOGY MARCHE EN FAMEN
Original Assignee
SMB TECHNOLOGY MARCHE EN FAMEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SMB TECHNOLOGY MARCHE EN FAMEN filed Critical SMB TECHNOLOGY MARCHE EN FAMEN
Publication of DE60105243D1 publication Critical patent/DE60105243D1/de
Application granted granted Critical
Publication of DE60105243T2 publication Critical patent/DE60105243T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60105243T 2000-09-22 2001-02-14 Oral anzuwendende tramadolhaltige Teilchen zur einmal täglichen Verabreichung Expired - Lifetime DE60105243T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00870214 2000-09-22
EP00870214 2000-09-22

Publications (2)

Publication Number Publication Date
DE60105243D1 true DE60105243D1 (de) 2004-10-07
DE60105243T2 DE60105243T2 (de) 2005-11-24

Family

ID=32946830

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60105243T Expired - Lifetime DE60105243T2 (de) 2000-09-22 2001-02-14 Oral anzuwendende tramadolhaltige Teilchen zur einmal täglichen Verabreichung

Country Status (5)

Country Link
EP (1) EP1190712B1 (de)
AT (1) ATE274906T1 (de)
DE (1) DE60105243T2 (de)
ES (1) ES2228789T3 (de)
PT (1) PT1190712E (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI319713B (en) 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US8487002B2 (en) 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
NZ565591A (en) 2005-09-09 2011-07-29 Labopharm Inc Trazodone and cross linked high amylose starch composition for once a day administration
CZ300468B6 (cs) * 2007-09-20 2009-05-27 Zentiva, A. S Léková forma obsahující tramadol s kontrolovaným uvolnováním po dobu 24 hodin a zpusob její prípravy
JP6005636B2 (ja) 2010-07-06 2016-10-12 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Ｇａｂａ類似体及びオピオイドを含む新規胃内滞留型剤形

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4329794C2 (de) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
US5395626A (en) * 1994-03-23 1995-03-07 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
AU2021997A (en) * 1996-03-08 1997-09-22 Nycomed Danmark A/S Modified release multiple-units dosage composition
DE19901687B4 (de) * 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
EP1146862B1 (de) * 1999-01-29 2003-04-23 Disphar International B.V. Pharmazeutische zusammensetzungen

Also Published As

Publication number Publication date
DE60105243T2 (de) 2005-11-24
ATE274906T1 (de) 2004-09-15
PT1190712E (pt) 2005-01-31
ES2228789T3 (es) 2005-04-16
EP1190712A1 (de) 2002-03-27
EP1190712B1 (de) 2004-09-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition