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DE60043702D1 - Prostaglandin-derivate - Google Patents

Prostaglandin-derivate

Info

Publication number
DE60043702D1
DE60043702D1 DE60043702T DE60043702T DE60043702D1 DE 60043702 D1 DE60043702 D1 DE 60043702D1 DE 60043702 T DE60043702 T DE 60043702T DE 60043702 T DE60043702 T DE 60043702T DE 60043702 D1 DE60043702 D1 DE 60043702D1
Authority
DE
Germany
Prior art keywords
group
cycloalkyl
alkyl
integer
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60043702T
Other languages
English (en)
Inventor
Fumie Sato
Tohru Tanami
Hideo Tanaka
Naoya Ono
Makoto Yagi
Hitomi Hirano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE60043702D1 publication Critical patent/DE60043702D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60043702T 1999-09-10 2000-09-08 Prostaglandin-derivate Expired - Lifetime DE60043702D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP25672799 1999-09-10
JP32380499 1999-11-15
JP2000189121 2000-06-23
PCT/JP2000/006162 WO2001019790A1 (fr) 1999-09-10 2000-09-08 Derives de prostaglandine

Publications (1)

Publication Number Publication Date
DE60043702D1 true DE60043702D1 (de) 2010-03-04

Family

ID=27334555

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60043702T Expired - Lifetime DE60043702D1 (de) 1999-09-10 2000-09-08 Prostaglandin-derivate

Country Status (14)

Country Link
US (1) US6740772B1 (de)
EP (1) EP1211242B1 (de)
JP (1) JP4563636B2 (de)
KR (1) KR100698433B1 (de)
CN (1) CN1222509C (de)
AT (1) ATE455098T1 (de)
AU (1) AU766983B2 (de)
CA (1) CA2384718C (de)
DE (1) DE60043702D1 (de)
DK (1) DK1211242T3 (de)
ES (1) ES2337981T3 (de)
HK (1) HK1048466B (de)
PT (1) PT1211242E (de)
WO (1) WO2001019790A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040266880A1 (en) * 2002-02-22 2004-12-30 Fumie Sato Antipruritics
DE60329008D1 (de) * 2002-07-12 2009-10-08 Taisho Pharmaceutical Co Ltd Prostaglandinderivate
EP1527781B1 (de) * 2002-08-09 2008-07-23 Taisho Pharmaceutical Co., Ltd Antipruritisches mittel
US7737182B2 (en) 2002-08-09 2010-06-15 Taisho Pharmaceutical Co., Ltd. Pharmaceuticals for xerosis
AU2003301900A1 (en) * 2002-11-13 2004-06-03 Fumie Sato Antipruritic drug
JP5382898B2 (ja) * 2004-02-06 2014-01-08 大正製薬株式会社 乾皮症治療剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029681A (en) 1976-02-13 1977-06-14 The Upjohn Company 13,14-Didehydro-PG analogs
HU206084B (en) 1987-07-17 1992-08-28 Schering Ag Process for producing 9-halogen-/z/-prostaglandin derivatives and pharmaceutical compositions comprising such active ingredient
US5891910A (en) 1987-07-17 1999-04-06 Schering Aktiengesellschaft 9-halogen-(Z) prostaglandin derivatives, process for their production and their use as pharmaceutical agents
DE4036140A1 (de) 1990-11-09 1992-05-14 Schering Ag 9-halogen-11ss-hydroxy-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JP2502009B2 (ja) 1992-06-08 1996-05-29 サンデン株式会社 自動販売機
KR950703527A (ko) * 1992-10-20 1995-09-20 후미에 사토 프로스타글란딘 유도체
JP3502952B2 (ja) * 1992-10-20 2004-03-02 大正製薬株式会社 プロスタグランジン誘導体
DE4330177A1 (de) * 1993-08-31 1995-03-02 Schering Ag Neue 9-Chlor-prostaglandin-derivate
JP3579448B2 (ja) * 1993-12-29 2004-10-20 大正製薬株式会社 プロスタグランジン誘導体、その塩およびその使用
JP3506485B2 (ja) * 1994-04-19 2004-03-15 大正製薬株式会社 プロスタグランジン誘導体
DE69922916T2 (de) * 1998-07-14 2005-06-09 Alcon Manufacturing Ltd., Fort Worth Polypropylenbasierte behälter für prostaglandin-enthaltende produkte

Also Published As

Publication number Publication date
US6740772B1 (en) 2004-05-25
EP1211242B1 (de) 2010-01-13
CA2384718C (en) 2009-12-01
AU766983B2 (en) 2003-10-30
JP4563636B2 (ja) 2010-10-13
CN1222509C (zh) 2005-10-12
KR100698433B1 (ko) 2007-03-22
EP1211242A4 (de) 2004-11-03
ATE455098T1 (de) 2010-01-15
DK1211242T3 (da) 2010-04-26
ES2337981T3 (es) 2010-05-03
CN1373752A (zh) 2002-10-09
HK1048466B (zh) 2006-04-07
HK1048466A1 (en) 2003-04-04
CA2384718A1 (en) 2001-03-22
KR20020043581A (ko) 2002-06-10
EP1211242A1 (de) 2002-06-05
PT1211242E (pt) 2010-02-10
WO2001019790A1 (fr) 2001-03-22
AU6876700A (en) 2001-04-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition