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ES2055241T3 - Compuestos anti-psicoticos. - Google Patents

Compuestos anti-psicoticos.

Info

Publication number
ES2055241T3
ES2055241T3 ES90114860T ES90114860T ES2055241T3 ES 2055241 T3 ES2055241 T3 ES 2055241T3 ES 90114860 T ES90114860 T ES 90114860T ES 90114860 T ES90114860 T ES 90114860T ES 2055241 T3 ES2055241 T3 ES 2055241T3
Authority
ES
Spain
Prior art keywords
represented
choh
alkyl
hydrogen
psychotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90114860T
Other languages
English (en)
Inventor
Albert A Carr
Francis P Miller
John M Kane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2055241T3 publication Critical patent/ES2055241T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

EL PRESENTE INVENTO ESTA DIRIGIDO A UNA NUEVA CLASE DE AGENTE TERAPEUTICO DE LA FORMULA: EN LA QUE Y ESTA REPRESENTADO POR CO O CHOH; T ESTA REPRESENTADO POR CO O CHOH; X ESTA REPRESENTADO POR HIDROGENO O POR ALQUIL C1-6; N ESTA REPRESENTADO POR LOS ENTEROS 3 O 4; R Y R1 SON CADA UNO INDEPENDIENTEMENTE REPRESENTADOS POR HIDROGENO, ALQUIL C1-6, ALCOXI C1-6, HALOGENO, -OH O -CF3; Y SUS SALES DE ADICCION DE ACIDO ACEPTABLES FARMACEUTICAMENTE, QUE SON UTILES COMO AGENTES ANTI-SICOTICOS Y COMO ANALGESICOS.
ES90114860T 1989-08-03 1990-08-02 Compuestos anti-psicoticos. Expired - Lifetime ES2055241T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38903689A 1989-08-03 1989-08-03

Publications (1)

Publication Number Publication Date
ES2055241T3 true ES2055241T3 (es) 1994-08-16

Family

ID=23536563

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90114860T Expired - Lifetime ES2055241T3 (es) 1989-08-03 1990-08-02 Compuestos anti-psicoticos.

Country Status (9)

Country Link
EP (1) EP0411631B1 (es)
JP (1) JP2954992B2 (es)
AT (1) ATE104294T1 (es)
AU (1) AU625238B2 (es)
CA (1) CA2022451C (es)
DD (1) DD296923A5 (es)
DE (1) DE69008069T2 (es)
DK (1) DK0411631T3 (es)
ES (1) ES2055241T3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
CA2097317C (en) * 1990-12-14 2002-02-12 Albert A. Carr Antiallergic piperdinyl benzimidazoles
GB9305644D0 (en) * 1993-03-18 1993-05-05 Merck Sharp & Dohme Therapeutic agents
EP0689535B1 (en) * 1993-03-18 1998-09-23 MERCK SHARP & DOHME LTD. Benzimidazole derivatives
GB9306578D0 (en) * 1993-03-30 1993-05-26 Merck Sharp & Dohme Therapeutic agents
AU6435594A (en) * 1993-04-15 1994-11-08 Merck Sharp & Dohme Limited Indole derivatives as dopamine d4 antagonists
US20120220603A1 (en) * 2009-09-04 2012-08-30 Zalicus Pharmaceuticals Ltd. Substituted heterocyclic derivatives for the treatment of pain and epilepsy
US10208023B2 (en) 2013-03-01 2019-02-19 Mark G. DeGiacomo Heterocyclic inhibitors of the sodium channel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles

Also Published As

Publication number Publication date
AU625238B2 (en) 1992-07-02
DE69008069D1 (de) 1994-05-19
CA2022451A1 (en) 1991-02-04
DD296923A5 (de) 1991-12-19
JP2954992B2 (ja) 1999-09-27
DE69008069T2 (de) 1994-07-28
AU6012390A (en) 1991-02-07
CA2022451C (en) 2001-01-23
EP0411631A1 (en) 1991-02-06
EP0411631B1 (en) 1994-04-13
ATE104294T1 (de) 1994-04-15
DK0411631T3 (da) 1994-05-16
JPH0366683A (ja) 1991-03-22

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