US7244349B2
(en)
|
1997-12-17 |
2007-07-17 |
Molecular Devices Corporation |
Multiaperture sample positioning and analysis system
|
US20020144905A1
(en)
|
1997-12-17 |
2002-10-10 |
Christian Schmidt |
Sample positioning and analysis system
|
DE19948473A1
(de)
*
|
1999-10-08 |
2001-04-12 |
Nmi Univ Tuebingen |
Verfahren und Vorrichtung zum Messen an in einer flüssigen Umgebung befindlichen Zellen
|
FR2802078B1
(fr)
*
|
1999-12-14 |
2003-10-03 |
Univ Joseph Fourier |
Microelectrode support de cellules a membrane excitable
|
AU2001271898B2
(en)
*
|
2000-07-07 |
2006-10-05 |
Bristol-Myers Squibb Company |
Electrophysiology configuration suitable for high throughput screening of compounds for drug discovery
|
US7270730B2
(en)
|
2000-08-04 |
2007-09-18 |
Essen Instruments, Inc. |
High-throughput electrophysiological measurement system
|
US7067046B2
(en)
|
2000-08-04 |
2006-06-27 |
Essen Instruments, Inc. |
System for rapid chemical activation in high-throughput electrophysiological measurements
|
AU2001287472A1
(en)
*
|
2000-09-19 |
2002-04-02 |
Cytion Sa |
Sample positioning and analysis system
|
US6932893B2
(en)
|
2000-10-02 |
2005-08-23 |
Sophion Bioscience A/S |
System for electrophysiological measurements
|
EP1322955B1
(de)
*
|
2000-10-02 |
2012-06-13 |
Sophion Bioscience A/S |
System für elektrophysiologische messungen
|
US6776896B1
(en)
|
2000-10-11 |
2004-08-17 |
Axon Instruments, Inc. |
Method of positioning cells for electrophysiological testing
|
WO2002055653A1
(fr)
*
|
2001-01-09 |
2002-07-18 |
Matsushita Electric Industrial Co., Ltd. |
Dispositif de mesure du potentiel extracellulaire, procede permettant de mesurer le potentiel extracellulaire a l'aide dudit dispositif et appareil utilise pour cribler rapidement le medicament apporte par ce dernier
|
US20060029955A1
(en)
|
2001-03-24 |
2006-02-09 |
Antonio Guia |
High-density ion transport measurement biochip devices and methods
|
EP1372828A4
(de)
|
2001-03-24 |
2008-10-29 |
Aviva Biosciences Corp |
Biochips mit ionentransporterfassungsstrukturen und verwendungsverfahren
|
WO2002103354A1
(en)
*
|
2001-06-20 |
2002-12-27 |
Sophion Bioscience A/S |
An apparatus and method for determining and/or monitoring electrophysiological properties of ion channels
|
US6899800B2
(en)
|
2001-06-20 |
2005-05-31 |
Axon Instruments, Inc. |
Polymeric electrode for electrophysiological testing
|
JP2003043009A
(ja)
*
|
2001-07-30 |
2003-02-13 |
Matsushita Electric Ind Co Ltd |
生体試料の発する物理化学的変化を検出するデバイスおよび装置
|
DE10142393C1
(de)
*
|
2001-08-30 |
2003-01-23 |
Fraunhofer Ges Forschung |
Vorrichtung und Verfahren zur Erfassung bioelektrischer Signale aus elektrophysiologisch aktiven Bereichen in Sphäroiden
|
DE10202887B4
(de)
*
|
2002-01-25 |
2004-05-06 |
Advalytix Ag |
Zellanalyseverfahren
|
WO2003067251A2
(en)
*
|
2002-02-05 |
2003-08-14 |
The University Court Of The University Of Glasgow |
Device for performing cell assays
|
EP2347824A3
(de)
|
2002-02-12 |
2012-03-07 |
Cellectricon Ab |
Systeme und Verfahren zur schnellen Änderung der Lösungsumgebung um Sensoren
|
US7470518B2
(en)
|
2002-02-12 |
2008-12-30 |
Cellectricon Ab |
Systems and method for rapidly changing the solution environment around sensors
|
GB0207845D0
(en)
*
|
2002-04-04 |
2002-05-15 |
Lgc Ltd |
Apparatus, methods and means for biochemical analysis
|
DK1495105T3
(da)
*
|
2002-04-17 |
2007-06-04 |
Sophion Bioscience As |
Substrat og fremgangsmåde til måling af elektrofysiologiske egenskaber for cellemenbraner
|
GB2398635A
(en)
*
|
2003-02-21 |
2004-08-25 |
Sophion Bioscience As |
A substrate providing a cell gigaseal for a patch clamp
|
CA2485099C
(en)
|
2002-05-04 |
2017-09-26 |
Aviva Biosciences Corporation |
Apparatus including ion transport detecting structures and methods of use
|
JP3624292B2
(ja)
*
|
2002-05-13 |
2005-03-02 |
松下電器産業株式会社 |
生体試料の活動信号計測装置および計測方法
|
ES2208082B1
(es)
*
|
2002-05-29 |
2005-09-16 |
Jose Luis Bardasano Rubio |
Dispositivo para la medida del potencial de la accion transmembrana en preparaciones celulares bajo la accion de campos electromagneticos de frecuencia e intensidad variables.
|
JP3945338B2
(ja)
*
|
2002-08-01 |
2007-07-18 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
JP3945317B2
(ja)
*
|
2002-06-05 |
2007-07-18 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
JP3925439B2
(ja)
*
|
2003-03-07 |
2007-06-06 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
JP4552423B2
(ja)
*
|
2003-11-21 |
2010-09-29 |
パナソニック株式会社 |
細胞外電位測定デバイスおよびこれを用いた細胞外電位の測定方法
|
US8202439B2
(en)
|
2002-06-05 |
2012-06-19 |
Panasonic Corporation |
Diaphragm and device for measuring cellular potential using the same, manufacturing method of the diaphragm
|
JP3861831B2
(ja)
*
|
2003-03-07 |
2006-12-27 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
WO2006132116A1
(ja)
|
2005-06-07 |
2006-12-14 |
Matsushita Electric Industrial Co., Ltd. |
細胞電気生理測定デバイスおよびその製造方法
|
WO2003104788A1
(ja)
|
2002-06-05 |
2003-12-18 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
WO2007072790A1
(ja)
|
2005-12-20 |
2007-06-28 |
Matsushita Electric Industrial Co., Ltd. |
細胞電気生理センサ
|
AU2003251124A1
(en)
*
|
2002-06-07 |
2003-12-22 |
Sophion Bioscience A/S |
Screening methods
|
US8263375B2
(en)
|
2002-12-20 |
2012-09-11 |
Acea Biosciences |
Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
|
US7560269B2
(en)
|
2002-12-20 |
2009-07-14 |
Acea Biosciences, Inc. |
Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
|
US8206903B2
(en)
|
2002-12-20 |
2012-06-26 |
Acea Biosciences |
Device and method for electroporation-based delivery of molecules into cells and dynamic monitoring of cell responses
|
US7732127B2
(en)
|
2002-12-20 |
2010-06-08 |
Acea Biosciences, Inc. |
Dynamic monitoring of cell adhesion and spreading using the RT-CES system
|
US7470533B2
(en)
|
2002-12-20 |
2008-12-30 |
Acea Biosciences |
Impedance based devices and methods for use in assays
|
CA2493108C
(en)
*
|
2002-07-20 |
2011-08-30 |
Xiaobo Wang |
Impedance based devices and methods for use in assays
|
US7468255B2
(en)
|
2002-12-20 |
2008-12-23 |
Acea Biosciences |
Method for assaying for natural killer, cytotoxic T-lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology
|
US7810380B2
(en)
|
2003-03-25 |
2010-10-12 |
Tearlab Research, Inc. |
Systems and methods for collecting tear film and measuring tear film osmolarity
|
WO2004018690A1
(en)
*
|
2002-08-21 |
2004-03-04 |
Cellectricon Ab |
System and method for obtaining and maintaining high resistance seals in patch clamp recordings
|
EP1801586B1
(de)
*
|
2002-08-21 |
2010-10-13 |
Cellectricon Ab |
System zur Gewinnung und Erhaltung hochresistenter Verschlüsse bei Patch-Clamp-Aufzeichnungen
|
FR2844052B1
(fr)
|
2002-08-28 |
2005-07-01 |
Commissariat Energie Atomique |
Dispositif de mesure de l'activite electrique d'elements biologiques et ses applications
|
US8232074B2
(en)
|
2002-10-16 |
2012-07-31 |
Cellectricon Ab |
Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells
|
US10539523B2
(en)
|
2002-12-20 |
2020-01-21 |
Acea Biosciences, Inc. |
System and method for monitoring cardiomyocyte beating, viability, morphology, and electrophysiological properties
|
US9612234B2
(en)
|
2008-05-05 |
2017-04-04 |
Acea Biosciences, Inc. |
Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (RTCA) cardio instruments
|
US10551371B2
(en)
|
2003-11-10 |
2020-02-04 |
Acea Biosciences, Inc. |
System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function
|
US10215748B2
(en)
|
2002-12-20 |
2019-02-26 |
Acea Biosciences, Inc. |
Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways
|
US11346797B2
(en)
|
2002-12-20 |
2022-05-31 |
Agilent Technologies, Inc. |
System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties
|
GB0303920D0
(en)
|
2003-02-21 |
2003-03-26 |
Sophion Bioscience As |
Capillary stop
|
EP1602922B1
(de)
|
2003-03-07 |
2016-01-13 |
Panasonic Intellectual Property Management Co., Ltd. |
Extrazellularpotential-messeinrichtung und verfahren zu ihrer herstellung
|
JP4728956B2
(ja)
*
|
2003-06-10 |
2011-07-20 |
イサム リサーチ デベロップメント カンパニー オブ ザ ヘブルー ユニバーシティ オブ エルサレム |
生体細胞との通信のための電子装置
|
EP1692258A4
(de)
|
2003-11-12 |
2007-03-21 |
Xiao Xu |
Elektronische echtzeit-zellwahrnehmungssysteme und anwendungen für tests auf zellbasis
|
CA2556219A1
(en)
*
|
2004-02-09 |
2005-08-25 |
Acea Biosciences, Inc. |
Methods for assaying cells using cell-substrate impedance monitoring
|
FR2866958B1
(fr)
|
2004-02-26 |
2006-08-04 |
Commissariat Energie Atomique |
Procede et dispositif de controle du positionnement d'un element biologique sur un support
|
WO2006012571A1
(en)
*
|
2004-07-23 |
2006-02-02 |
Electronic Bio Sciences, Llc |
Method and apparatus for sensing a time varying current passing through an ion channel
|
JPWO2006022092A1
(ja)
|
2004-08-25 |
2008-05-08 |
松下電器産業株式会社 |
細胞電位測定プローブ
|
JP2006184207A
(ja)
*
|
2004-12-28 |
2006-07-13 |
Matsushita Electric Ind Co Ltd |
細胞膜の特性および状態の少なくとも一方の電気的測定方法および電気的測定装置
|
US20060216203A1
(en)
*
|
2005-03-28 |
2006-09-28 |
Mds Sciex (Us) A Division Of Mds Pharma Services (Us) Inc. |
Multiwell sample plate with integrated impedance electrodes and connection scheme
|
JP4661539B2
(ja)
*
|
2005-11-11 |
2011-03-30 |
パナソニック株式会社 |
細胞電気生理センサおよびその製造方法
|
US7608417B2
(en)
*
|
2005-11-14 |
2009-10-27 |
Panasonic Corporation |
Cell electro-physiological sensor and method of manufacturing the same
|
JP2009156572A
(ja)
*
|
2006-04-06 |
2009-07-16 |
National Institutes Of Natural Sciences |
イオンチャンネルタンパク質バイオセンサー
|
US8071363B2
(en)
|
2006-05-25 |
2011-12-06 |
Panasonic Corporation |
Chip for cell electrophysiological sensor, cell electrophysiological sensor using the same, and manufacturing method of chip for cell electrophysiological sensor
|
EP2037258A4
(de)
|
2006-07-06 |
2013-12-04 |
Panasonic Corp |
Vorrichtung für zellelektrophysiologiesensor, zellelektrophysiologiesensor unter verwendung der vorrichtung sowie verfahren zur herstellung der zellelektrophysiologiesensorvorrichtung
|
US8041515B2
(en)
|
2006-09-20 |
2011-10-18 |
Acea Biosciences, Inc. |
Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents
|
EP2153224B1
(de)
*
|
2007-05-04 |
2012-12-19 |
Tecella, LLC |
Teilsystem und verfahren zur verwendung in patch-clamp-systemen
|
EP2172415B1
(de)
|
2007-09-11 |
2016-11-02 |
Panasonic Intellectual Property Management Co., Ltd. |
Silizium-struktur und methode zu deren herstellung
|
WO2009137440A1
(en)
|
2008-05-05 |
2009-11-12 |
Acea Biosciences, Inc. |
Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution
|
CA2804564A1
(en)
|
2010-07-09 |
2012-01-12 |
Sophion Bioscience A/S |
A chip assembly for use in a microfluidic analysis system
|
JP5575623B2
(ja)
*
|
2010-12-03 |
2014-08-20 |
マルボシ酢株式会社 |
誘電特性測定用耐圧容器センサーに用いる絶縁体
|
JP6037717B2
(ja)
*
|
2011-12-20 |
2016-12-07 |
国立研究開発法人科学技術振興機構 |
プレーナーパッチクランプ装置、該装置用電極部及び細胞イオンチャンネル電流計測方法
|
JP6290096B2
(ja)
*
|
2012-01-09 |
2018-03-07 |
ソフィオン・バイオサイエンス・アクティーゼルスカブ |
改良されたパッチエリアの細胞付着性
|
DE102013007295B4
(de)
*
|
2013-04-26 |
2015-06-25 |
Universität Rostock |
Elektrophysiologische Messanordnung und elektrophysiologisches Messverfahren
|
EP3040410B1
(de)
|
2013-08-30 |
2018-04-25 |
Japan Science and Technology Agency |
Flache patch-clamp-vorrichtung und verfahren verwendend die patch-clamp vorrichtung
|
EP3792615A1
(de)
|
2014-09-23 |
2021-03-17 |
Tearlab Research, Inc. |
System zur integration einer mikrofluidischen tränenprobenahme und lateral-flow-analyse von interessierenden analyten
|
US12066428B2
(en)
|
2015-11-20 |
2024-08-20 |
Agilent Technologies, Inc. |
Cell-substrate impedance monitoring of cancer cells
|
WO2017175879A1
(ja)
*
|
2016-04-05 |
2017-10-12 |
シャープ株式会社 |
センサ装置、検出方法、及びセンサユニット
|
JP6676486B2
(ja)
*
|
2016-04-05 |
2020-04-08 |
シャープ株式会社 |
検出方法
|
WO2018161063A1
(en)
|
2017-03-03 |
2018-09-07 |
Acea Biosciences, Inc. |
METHODS AND SYSTEMS FOR FUNCTIONAL MATURATION OF iPSC AND ESC DERIVED CARDIOMYOCYTES
|
TWI695166B
(zh)
*
|
2017-11-03 |
2020-06-01 |
國立臺灣大學 |
一種多離子感測電極陣列試片及其感測裝置
|
JP7229110B2
(ja)
*
|
2019-06-25 |
2023-02-27 |
株式会社Screenホールディングス |
細胞電位測定装置
|
JP7469092B2
(ja)
*
|
2020-03-23 |
2024-04-16 |
株式会社Screenホールディングス |
細胞保持容器
|
US20210301245A1
(en)
|
2020-03-29 |
2021-09-30 |
Agilent Technologies, Inc. |
Systems and methods for electronically and optically monitoring biological samples
|
WO2023131694A1
(en)
|
2022-01-07 |
2023-07-13 |
Sophion Bioscience A/S |
Pipette guidance in multiple-well plate patch-clamp
|
JP2025502078A
(ja)
|
2022-01-07 |
2025-01-24 |
ソフィオン・バイオサイエンス・アクティーゼルスカブ |
半自動パッチクランプ装置およびパッチクランプ手順を実行する方法
|