DE59006037D1 - Verfahren zur Herstellung von 1-(Aminomethyl)cyclohexanessigsäure. - Google Patents
Verfahren zur Herstellung von 1-(Aminomethyl)cyclohexanessigsäure.Info
- Publication number
- DE59006037D1 DE59006037D1 DE59006037T DE59006037T DE59006037D1 DE 59006037 D1 DE59006037 D1 DE 59006037D1 DE 59006037 T DE59006037 T DE 59006037T DE 59006037 T DE59006037 T DE 59006037T DE 59006037 D1 DE59006037 D1 DE 59006037D1
- Authority
- DE
- Germany
- Prior art keywords
- cyanocyclohexyl
- aminomethyl
- preparation
- acetic acid
- cyclohexane acetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH412889 | 1989-11-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE59006037D1 true DE59006037D1 (de) | 1994-07-14 |
Family
ID=4270351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE59006037T Expired - Fee Related DE59006037D1 (de) | 1989-11-16 | 1990-11-14 | Verfahren zur Herstellung von 1-(Aminomethyl)cyclohexanessigsäure. |
Country Status (14)
Country | Link |
---|---|
US (2) | US5095148A (no) |
EP (1) | EP0432504B1 (no) |
JP (1) | JPH03176459A (no) |
AT (1) | ATE106861T1 (no) |
CA (1) | CA2030107A1 (no) |
DE (1) | DE59006037D1 (no) |
DK (1) | DK0432504T3 (no) |
ES (1) | ES2057334T3 (no) |
FI (1) | FI905584A (no) |
IL (1) | IL96360A0 (no) |
NO (1) | NO177531C (no) |
PT (1) | PT95894B (no) |
RU (1) | RU2029761C1 (no) |
YU (1) | YU215290A (no) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ293759B6 (cs) * | 1996-03-14 | 2004-07-14 | Warner-Lambert Company | Substituovaná cyklická aminokyselina, její použití a farmaceutický prostředek na její bázi |
US6372792B1 (en) | 1996-04-26 | 2002-04-16 | Guy Chouinard | Method for treating anxiety, anxiety disorders and insomnia |
US6255526B1 (en) | 1996-12-24 | 2001-07-03 | Teva Pharmaceutical Industries Ltd. | Preparation of gabapentin |
WO1999018063A2 (en) | 1997-10-07 | 1999-04-15 | Warner-Lambert Company | Process for preparing a cyclic amino acid anticonvulsant compound |
HU225502B1 (en) * | 1998-12-29 | 2007-01-29 | Richter Gedeon Vegyeszet | Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates |
CZ200339A3 (cs) * | 2000-06-16 | 2003-06-18 | Teva Pharmaceutical Industries Ltd. | Stabilní gabapentin vykazující neutrální pH |
AU2003262383A1 (en) * | 2002-04-16 | 2003-11-03 | Taro Pharmaceutical Industries Ltd. | Process for preparing gabapentin |
AU2002356424A1 (en) * | 2002-11-18 | 2004-06-15 | Nicholas Piramal India Limited | Improved process for preparation of gabapentin |
EP1628656B1 (en) * | 2003-03-25 | 2008-10-15 | Kiel Laboratories, Inc. | Gabapentin tannate in liquid and/or semi-solid dosage forms |
EP1622603A4 (en) | 2003-03-25 | 2010-03-24 | Kiel Lab Inc | GABAPENTINIC PHENOLIC ACID SALTS IN SOLID DOSAGE FORMS AND METHODS OF USE |
WO2004093866A1 (en) * | 2003-03-25 | 2004-11-04 | Kiel Laboratories, Inc. | Process for preparing phenolic acid salts of gabapentin |
US7439387B2 (en) * | 2003-04-21 | 2008-10-21 | Matrix Laboratories Ltd. | Process for the preparation of Gabapentin form-II |
US20050187295A1 (en) * | 2004-02-19 | 2005-08-25 | Surendra Kalyan | Processes for the preparation of gabapentin |
GB0416228D0 (en) | 2004-07-20 | 2004-08-25 | Sandoz Ind Products S A | Process for the preparation of gabapentin |
EP2038249B1 (en) * | 2006-06-30 | 2013-09-11 | ZaCh System S.p.A. | Process for preparing gabapentin |
CN101585778B (zh) * | 2008-05-19 | 2014-08-13 | 上海臣邦医药科技有限公司 | 一种普瑞巴林制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2264354A (en) * | 1937-12-22 | 1941-12-02 | Ig Farbenindustrie Ag | Addition products of dienes and unsaturated esters, ketones, or nitriles |
US2467927A (en) * | 1947-05-29 | 1949-04-19 | Goodrich Co B F | Preparation of monomeric alkyl alpha-cyano-acrylates |
DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE2611690A1 (de) * | 1976-03-19 | 1977-09-22 | Goedecke Ag | Cyclische sulfonyloxyimide |
YU162789A (en) * | 1988-09-01 | 1990-12-31 | Lonza Ag | 2-aza-4-(alcoxycarbonyl) spiro/4,5/decan-3-ones |
AU633612B2 (en) * | 1989-08-25 | 1993-02-04 | Warner-Lambert Company | Improved process for cyclic amino acid anticonvulsant compounds |
-
1990
- 1990-11-12 FI FI905584A patent/FI905584A/fi not_active IP Right Cessation
- 1990-11-13 YU YU215290A patent/YU215290A/sh unknown
- 1990-11-14 EP EP90121827A patent/EP0432504B1/de not_active Expired - Lifetime
- 1990-11-14 ES ES90121827T patent/ES2057334T3/es not_active Expired - Lifetime
- 1990-11-14 DK DK90121827.1T patent/DK0432504T3/da active
- 1990-11-14 DE DE59006037T patent/DE59006037D1/de not_active Expired - Fee Related
- 1990-11-14 AT AT90121827T patent/ATE106861T1/de not_active IP Right Cessation
- 1990-11-14 JP JP2306361A patent/JPH03176459A/ja active Pending
- 1990-11-15 CA CA002030107A patent/CA2030107A1/en not_active Abandoned
- 1990-11-15 PT PT95894A patent/PT95894B/pt not_active IP Right Cessation
- 1990-11-15 NO NO904953A patent/NO177531C/no unknown
- 1990-11-15 RU SU904831479A patent/RU2029761C1/ru active
- 1990-11-15 US US07/612,985 patent/US5095148A/en not_active Expired - Fee Related
- 1990-11-15 IL IL96360A patent/IL96360A0/xx unknown
-
1991
- 1991-07-10 US US07/727,939 patent/US5130455A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NO177531B (no) | 1995-06-26 |
NO177531C (no) | 1995-10-04 |
US5095148A (en) | 1992-03-10 |
NO904953D0 (no) | 1990-11-15 |
PT95894A (pt) | 1991-09-13 |
EP0432504B1 (de) | 1994-06-08 |
ES2057334T3 (es) | 1994-10-16 |
IL96360A0 (en) | 1991-08-16 |
ATE106861T1 (de) | 1994-06-15 |
CA2030107A1 (en) | 1991-05-17 |
EP0432504A1 (de) | 1991-06-19 |
YU215290A (sh) | 1993-05-28 |
RU2029761C1 (ru) | 1995-02-27 |
NO904953L (no) | 1991-05-21 |
FI905584A0 (fi) | 1990-11-12 |
DK0432504T3 (da) | 1994-07-04 |
FI905584A (fi) | 1991-05-17 |
PT95894B (pt) | 1998-01-30 |
JPH03176459A (ja) | 1991-07-31 |
US5130455A (en) | 1992-07-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |