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DE3884870D1 - Verfahren zur Herstellung von Vitamin-D-Derivaten. - Google Patents

Verfahren zur Herstellung von Vitamin-D-Derivaten.

Info

Publication number
DE3884870D1
DE3884870D1 DE88306245T DE3884870T DE3884870D1 DE 3884870 D1 DE3884870 D1 DE 3884870D1 DE 88306245 T DE88306245 T DE 88306245T DE 3884870 T DE3884870 T DE 3884870T DE 3884870 D1 DE3884870 D1 DE 3884870D1
Authority
DE
Germany
Prior art keywords
vitamin
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE88306245T
Other languages
English (en)
Other versions
DE3884870T2 (de
Inventor
Sadafumi Omura
Akiko Mikami
Joji Sasaki
Kazutoshi Mizoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mercian Corp
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of DE3884870D1 publication Critical patent/DE3884870D1/de
Application granted granted Critical
Publication of DE3884870T2 publication Critical patent/DE3884870T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/826Actinomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/872Nocardia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE88306245T 1987-07-08 1988-07-08 Verfahren zur Herstellung von Vitamin-D-Derivaten. Expired - Lifetime DE3884870T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17066987 1987-07-08
JP33132387 1987-12-26

Publications (2)

Publication Number Publication Date
DE3884870D1 true DE3884870D1 (de) 1993-11-18
DE3884870T2 DE3884870T2 (de) 1994-02-03

Family

ID=26493597

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88306245T Expired - Lifetime DE3884870T2 (de) 1987-07-08 1988-07-08 Verfahren zur Herstellung von Vitamin-D-Derivaten.

Country Status (5)

Country Link
US (1) US4892821A (de)
EP (1) EP0298757B1 (de)
KR (1) KR960004452B1 (de)
DE (1) DE3884870T2 (de)
ES (1) ES2047033T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3201411B2 (ja) * 1990-06-15 2001-08-20 メルシャン株式会社 ビタミンd類の生物学的製造方法
EP0916736B1 (de) * 1996-06-27 2005-11-16 Mercian Corporation Biologisches verfahren zur herstellung von 25-hydroxylierten steroiden
TW584627B (en) 1996-07-01 2004-04-21 Chugai Pharmaceutical Co Ltd The method for purifying vitamin D derivatives and its crystalline products
WO2000061776A1 (fr) * 1999-04-14 2000-10-19 Mercian Corporation Derives de vitamine d et procede de production correspondant
SI3095447T1 (sl) 2006-02-03 2022-02-28 Opko Renal, Llc Zdravljenje pomanjkanja vitamina D s 25-hidroksivitaminom D2 in 25-hidroksivitaminom D3
JP4998957B2 (ja) 2006-05-31 2012-08-15 日本マイクロバイオファーマ株式会社 水酸化酵素遺伝子及びその用途
JP5563296B2 (ja) 2006-06-21 2014-07-30 プロヴェンティヴ セラピュティックス リミテッド ライアビリティ カンパニー 二次性副甲状腺機能亢進症の治療及び予防方法
ES2403107T3 (es) 2007-04-25 2013-05-14 Cytochroma Inc. Método de tratamiento de insuficiencia y deficiencia de vitamina D
ES2956794T3 (es) 2007-04-25 2023-12-28 Eirgen Pharma Ltd Liberación controlada de 25-hidroxivitamina D
ES2954932T3 (es) 2008-04-02 2023-11-27 Eirgen Pharma Ltd Métodos, composiciones, usos y kits útiles para la deficiencia de vitamina D y trastornos relacionados
US8545915B2 (en) * 2008-05-02 2013-10-01 Oakshire Holdings, Inc. Method and apparatus for vitamin D enhancement in mushrooms
RS60087B1 (sr) 2010-03-29 2020-05-29 Opko Ireland Global Holdings Ltd Postupci i kompozicije za snižavanje nivoa paratireoidnog hormona
US20160205981A1 (en) 2012-09-27 2016-07-21 Oakshire Holdings, Inc. Method and apparatus for vitamin d enhancement in mushrooms
US9326540B2 (en) 2012-09-27 2016-05-03 Oakshire Holdings, Inc. Method and apparatus for vitamin D enhancement in mushrooms
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
AU2017253821B2 (en) 2016-03-28 2022-11-03 Opko Ireland Global Holdings, Limited Methods of vitamin D treatment

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same
US4279826A (en) * 1980-09-22 1981-07-21 Wisconsin Alumni Research Foundation 23,25-Dihydroxyvitamin D3
US4338250A (en) * 1981-04-27 1982-07-06 Wisconsin Alumni Research Foundation 1-Hydroxylation process
US4502991A (en) * 1983-08-18 1985-03-05 Wisconsin Alumni Research Foundation 23,23-Difluoro-1α,25-dihydroxy-vitamin D3
US4719205A (en) * 1984-01-30 1988-01-12 Wisconsin Alumini Research Foundation Side-chain unsaturated 1-hydroxyvitamin D compounds
US4689180A (en) * 1984-01-30 1987-08-25 Wisconsin Alumni Research Foundation 1α,25-dihydroxy-22Z-dehydroxyvitamin D compound
JPS6144860A (ja) * 1984-08-10 1986-03-04 Taisho Pharmaceut Co Ltd 1α.25−ジヒドロキシ−26.27−ジメチルビタミンD↓3
US4717721A (en) * 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity

Also Published As

Publication number Publication date
KR960004452B1 (ko) 1996-04-06
ES2047033T3 (es) 1994-02-16
EP0298757B1 (de) 1993-10-13
EP0298757A1 (de) 1989-01-11
DE3884870T2 (de) 1994-02-03
US4892821A (en) 1990-01-09
KR890001566A (ko) 1989-03-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MERCIAN CORP., TOKIO/TOKYO, JP