DE3884870D1 - Verfahren zur Herstellung von Vitamin-D-Derivaten. - Google Patents
Verfahren zur Herstellung von Vitamin-D-Derivaten.Info
- Publication number
- DE3884870D1 DE3884870D1 DE88306245T DE3884870T DE3884870D1 DE 3884870 D1 DE3884870 D1 DE 3884870D1 DE 88306245 T DE88306245 T DE 88306245T DE 3884870 T DE3884870 T DE 3884870T DE 3884870 D1 DE3884870 D1 DE 3884870D1
- Authority
- DE
- Germany
- Prior art keywords
- vitamin
- derivatives
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003710 vitamin D derivatives Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/826—Actinomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/872—Nocardia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17066987 | 1987-07-08 | ||
JP33132387 | 1987-12-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3884870D1 true DE3884870D1 (de) | 1993-11-18 |
DE3884870T2 DE3884870T2 (de) | 1994-02-03 |
Family
ID=26493597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE88306245T Expired - Lifetime DE3884870T2 (de) | 1987-07-08 | 1988-07-08 | Verfahren zur Herstellung von Vitamin-D-Derivaten. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4892821A (de) |
EP (1) | EP0298757B1 (de) |
KR (1) | KR960004452B1 (de) |
DE (1) | DE3884870T2 (de) |
ES (1) | ES2047033T3 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3201411B2 (ja) * | 1990-06-15 | 2001-08-20 | メルシャン株式会社 | ビタミンd類の生物学的製造方法 |
EP0916736B1 (de) * | 1996-06-27 | 2005-11-16 | Mercian Corporation | Biologisches verfahren zur herstellung von 25-hydroxylierten steroiden |
TW584627B (en) | 1996-07-01 | 2004-04-21 | Chugai Pharmaceutical Co Ltd | The method for purifying vitamin D derivatives and its crystalline products |
WO2000061776A1 (fr) * | 1999-04-14 | 2000-10-19 | Mercian Corporation | Derives de vitamine d et procede de production correspondant |
SI3095447T1 (sl) | 2006-02-03 | 2022-02-28 | Opko Renal, Llc | Zdravljenje pomanjkanja vitamina D s 25-hidroksivitaminom D2 in 25-hidroksivitaminom D3 |
JP4998957B2 (ja) | 2006-05-31 | 2012-08-15 | 日本マイクロバイオファーマ株式会社 | 水酸化酵素遺伝子及びその用途 |
JP5563296B2 (ja) | 2006-06-21 | 2014-07-30 | プロヴェンティヴ セラピュティックス リミテッド ライアビリティ カンパニー | 二次性副甲状腺機能亢進症の治療及び予防方法 |
ES2403107T3 (es) | 2007-04-25 | 2013-05-14 | Cytochroma Inc. | Método de tratamiento de insuficiencia y deficiencia de vitamina D |
ES2956794T3 (es) | 2007-04-25 | 2023-12-28 | Eirgen Pharma Ltd | Liberación controlada de 25-hidroxivitamina D |
ES2954932T3 (es) | 2008-04-02 | 2023-11-27 | Eirgen Pharma Ltd | Métodos, composiciones, usos y kits útiles para la deficiencia de vitamina D y trastornos relacionados |
US8545915B2 (en) * | 2008-05-02 | 2013-10-01 | Oakshire Holdings, Inc. | Method and apparatus for vitamin D enhancement in mushrooms |
RS60087B1 (sr) | 2010-03-29 | 2020-05-29 | Opko Ireland Global Holdings Ltd | Postupci i kompozicije za snižavanje nivoa paratireoidnog hormona |
US20160205981A1 (en) | 2012-09-27 | 2016-07-21 | Oakshire Holdings, Inc. | Method and apparatus for vitamin d enhancement in mushrooms |
US9326540B2 (en) | 2012-09-27 | 2016-05-03 | Oakshire Holdings, Inc. | Method and apparatus for vitamin D enhancement in mushrooms |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
AU2017253821B2 (en) | 2016-03-28 | 2022-11-03 | Opko Ireland Global Holdings, Limited | Methods of vitamin D treatment |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4284577A (en) * | 1979-02-16 | 1981-08-18 | Sachiko Yamada | Novel vitamin D3 derivative and process for preparing the same |
US4279826A (en) * | 1980-09-22 | 1981-07-21 | Wisconsin Alumni Research Foundation | 23,25-Dihydroxyvitamin D3 |
US4338250A (en) * | 1981-04-27 | 1982-07-06 | Wisconsin Alumni Research Foundation | 1-Hydroxylation process |
US4502991A (en) * | 1983-08-18 | 1985-03-05 | Wisconsin Alumni Research Foundation | 23,23-Difluoro-1α,25-dihydroxy-vitamin D3 |
US4719205A (en) * | 1984-01-30 | 1988-01-12 | Wisconsin Alumini Research Foundation | Side-chain unsaturated 1-hydroxyvitamin D compounds |
US4689180A (en) * | 1984-01-30 | 1987-08-25 | Wisconsin Alumni Research Foundation | 1α,25-dihydroxy-22Z-dehydroxyvitamin D compound |
JPS6144860A (ja) * | 1984-08-10 | 1986-03-04 | Taisho Pharmaceut Co Ltd | 1α.25−ジヒドロキシ−26.27−ジメチルビタミンD↓3 |
US4717721A (en) * | 1985-05-30 | 1988-01-05 | Howard W. Bremer | Sidechain homo-vitamin D compounds with preferential anti-cancer activity |
-
1988
- 1988-07-05 US US07/215,316 patent/US4892821A/en not_active Expired - Lifetime
- 1988-07-07 KR KR1019880008420A patent/KR960004452B1/ko not_active IP Right Cessation
- 1988-07-08 EP EP88306245A patent/EP0298757B1/de not_active Expired - Lifetime
- 1988-07-08 ES ES88306245T patent/ES2047033T3/es not_active Expired - Lifetime
- 1988-07-08 DE DE88306245T patent/DE3884870T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR960004452B1 (ko) | 1996-04-06 |
ES2047033T3 (es) | 1994-02-16 |
EP0298757B1 (de) | 1993-10-13 |
EP0298757A1 (de) | 1989-01-11 |
DE3884870T2 (de) | 1994-02-03 |
US4892821A (en) | 1990-01-09 |
KR890001566A (ko) | 1989-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: MERCIAN CORP., TOKIO/TOKYO, JP |