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DE3874229D1 - Verwendung von dioxopiperidin-derivaten zur herstellung eines topischen praeparates als analgetika. - Google Patents

Verwendung von dioxopiperidin-derivaten zur herstellung eines topischen praeparates als analgetika.

Info

Publication number
DE3874229D1
DE3874229D1 DE8888305317T DE3874229T DE3874229D1 DE 3874229 D1 DE3874229 D1 DE 3874229D1 DE 8888305317 T DE8888305317 T DE 8888305317T DE 3874229 T DE3874229 T DE 3874229T DE 3874229 D1 DE3874229 D1 DE 3874229D1
Authority
DE
Germany
Prior art keywords
prepair
analgetic
topical
production
dioxopiperidine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888305317T
Other languages
English (en)
Other versions
DE3874229T2 (de
Inventor
Malcolm Henry Traffod Roberts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878714033A external-priority patent/GB8714033D0/en
Priority claimed from GB878714374A external-priority patent/GB8714374D0/en
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Publication of DE3874229D1 publication Critical patent/DE3874229D1/de
Application granted granted Critical
Publication of DE3874229T2 publication Critical patent/DE3874229T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE8888305317T 1987-06-16 1988-06-10 Verwendung von dioxopiperidin-derivaten zur herstellung eines topischen praeparates als analgetika. Expired - Fee Related DE3874229T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878714033A GB8714033D0 (en) 1987-06-16 1987-06-16 Dioxopiperidine derivatives as analgesics
GB878714374A GB8714374D0 (en) 1987-06-19 1987-06-19 Dioxopiperidine derivatives

Publications (2)

Publication Number Publication Date
DE3874229D1 true DE3874229D1 (de) 1992-10-08
DE3874229T2 DE3874229T2 (de) 1993-03-25

Family

ID=26292364

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888305317T Expired - Fee Related DE3874229T2 (de) 1987-06-16 1988-06-10 Verwendung von dioxopiperidin-derivaten zur herstellung eines topischen praeparates als analgetika.

Country Status (10)

Country Link
US (1) US4871750A (de)
EP (1) EP0295836B1 (de)
JP (1) JPS6416763A (de)
AU (1) AU606424B2 (de)
DE (1) DE3874229T2 (de)
DK (1) DK328288A (de)
GB (1) GB2205745B (de)
IL (1) IL86745A0 (de)
PH (1) PH24807A (de)
PT (1) PT87737B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177086A (en) * 1988-11-10 1993-01-05 National Research Development Corporation Memory-enhancing compositions containing dioxopiperidine derivatives
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US5589480A (en) * 1994-08-17 1996-12-31 Elkhoury; George F. Topical application of opioid analgesic drugs such as morphine
US5866143A (en) * 1995-03-24 1999-02-02 El Khoury And Stein, Ltd. Topical application of opioid drugs such as morphine for relief of itching and skin disease
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
US5919473A (en) * 1997-05-12 1999-07-06 Elkhoury; George F. Methods and devices for delivering opioid analgesics to wounds via a subdermal implant
US6143278A (en) * 1998-02-23 2000-11-07 Elkhoury; George F. Topical application of opioid analgesic drugs such as morphine
US6011022A (en) * 1998-03-03 2000-01-04 El Khoury; George F. Topical application of muscarinic analgesic drugs such as neostigmine
US5994330A (en) * 1998-11-09 1999-11-30 El Khoury; Georges F. Topical application of muscarinic agents such as neostigmine for treatment of acne and other inflammatory conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1455687A (en) * 1972-12-28 1976-11-17 Aspro Nicholas Ltd Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines
US4461771A (en) * 1983-03-01 1984-07-24 Gittos Maurice W Treatment of migraine with dioxopiperidine derivatives
AT392276B (de) * 1984-01-25 1991-02-25 Glaxo Group Ltd Verfahren zur herstellung von neuen tetrahydrocarbazol-derivaten
EP0452765B1 (de) * 1985-09-11 1999-10-20 Btg International Limited Pharmazeutische Zubereitungen und medizinische Verwendungen von Dioxopiperidinderivaten, insbesondere als Verstärker der Immunantwort sowie als antivirale und antibakterielle Wirkstoffe
CA1316112C (en) * 1986-09-08 1993-04-13 Maurice Ward Gittos Anxiolytic compositions containing dioxopiperidine derivatives
GB8626936D0 (en) * 1986-11-11 1986-12-10 Ferrosan As Treatment

Also Published As

Publication number Publication date
EP0295836A2 (de) 1988-12-21
EP0295836A3 (en) 1989-07-19
AU606424B2 (en) 1991-02-07
PH24807A (en) 1990-10-30
GB8813796D0 (en) 1988-07-13
DK328288A (da) 1988-12-17
GB2205745A (en) 1988-12-21
PT87737A (pt) 1989-05-31
IL86745A0 (en) 1988-11-30
DK328288D0 (da) 1988-06-15
AU1767688A (en) 1988-12-22
GB2205745B (en) 1990-09-19
EP0295836B1 (de) 1992-09-02
US4871750A (en) 1989-10-03
PT87737B (pt) 1994-09-30
DE3874229T2 (de) 1993-03-25
JPS6416763A (en) 1989-01-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee