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DE3765181D1 - Isocarbacycline und verfahren zu ihrer herstellung. - Google Patents

Isocarbacycline und verfahren zu ihrer herstellung.

Info

Publication number
DE3765181D1
DE3765181D1 DE8787303883T DE3765181T DE3765181D1 DE 3765181 D1 DE3765181 D1 DE 3765181D1 DE 8787303883 T DE8787303883 T DE 8787303883T DE 3765181 T DE3765181 T DE 3765181T DE 3765181 D1 DE3765181 D1 DE 3765181D1
Authority
DE
Germany
Prior art keywords
isocarbacycline
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787303883T
Other languages
English (en)
Inventor
Atsuo Hazato
Toshio Tanaka
Noriaki Okamura
Kiyoahi Bannai
Seizi Kurozumi
Masaaki Suzuki
Ryoji Noyori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61099470A external-priority patent/JPS62258330A/ja
Priority claimed from JP21911786A external-priority patent/JPH0714948B2/ja
Priority claimed from JP61219118A external-priority patent/JPS6377853A/ja
Priority claimed from JP21911986A external-priority patent/JP2713333B2/ja
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of DE3765181D1 publication Critical patent/DE3765181D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8787303883T 1986-05-01 1987-04-30 Isocarbacycline und verfahren zu ihrer herstellung. Expired - Lifetime DE3765181D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP61099470A JPS62258330A (ja) 1986-05-01 1986-05-01 ６，７−二置換−２−ヒドロキシ−３−メチレンビシクロ〔３．３．０〕オクタン類の製造法
JP21911786A JPH0714948B2 (ja) 1986-09-19 1986-09-19 イソカルバサイクリン類の製法
JP61219118A JPS6377853A (ja) 1986-09-19 1986-09-19 イソカルバサイクリン類およびその製造法
JP21911986A JP2713333B2 (ja) 1986-09-19 1986-09-19 イソカルバサイクリン類及びその製造法

Publications (1)

Publication Number Publication Date
DE3765181D1 true DE3765181D1 (de) 1990-10-31

Family

ID=27468736

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787303883T Expired - Lifetime DE3765181D1 (de) 1986-05-01 1987-04-30 Isocarbacycline und verfahren zu ihrer herstellung.

Country Status (4)

Country Link
US (1) US4788319A (de)
EP (1) EP0247740B1 (de)
KR (1) KR940003361B1 (de)
DE (1) DE3765181D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206416A (en) * 1985-09-13 1993-04-27 Teijin Limited Isocarbacyclin derivative
US5283349A (en) * 1985-09-13 1994-02-01 Teijin Limited 2,6,7-trisubstituted-3-methylenebicyclo(3.3.0)-octanes, and process for production thereof
DE68927885T2 (de) * 1988-12-23 1997-06-26 Teijin Ltd Verwendung von isokarbacyclinen zur vorbeugung oder behandlung von organkrankheiten
US5364883A (en) * 1988-12-23 1994-11-15 Teijin Limited Isocarbocyclins for the treatment of liver and kidney diseases
US5216187A (en) * 1989-12-05 1993-06-01 Daiso Co., Ltd. Optically active 2-methylenepentane derivative and process for preparing same
DE4202665A1 (de) * 1992-01-28 1993-07-29 Schering Ag Prostacyclin- und carbacyclinderivate als mittel zur behandlung von multipler sklerose
US20140114086A1 (en) * 2012-10-22 2014-04-24 The University Of North Carolina At Greensboro Clinprost, Isocarbacyclin And Analogs Thereof And Methods Of Making The Same

Also Published As

Publication number Publication date
EP0247740B1 (de) 1990-09-26
US4788319A (en) 1988-11-29
KR870011087A (ko) 1987-12-19
EP0247740A2 (de) 1987-12-02
EP0247740A3 (en) 1988-01-27
KR940003361B1 (ko) 1994-04-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee