DE3316597C1 - Gelatinous preparation, and the use thereof as a medicament - Google Patents

Abstract

A gelatinous preparation based on a neutralised, high-molecular-weight polyacrylic acid and water and containing a dye and isopropanol, menthol, camphor and optionally rosemary oil and arnica petal extract for use as a medicament and drug in human and veterinary medicine.

Description

The invention relates to a gel-like preparation based on a neutralized polyacrylic acid and Water that, in order to be usable as a care product, still has a certain combination of active ingredients contains. It can be used as a care product in both human and veterinary areas, however, the veterinary sector is preferred and use as a care product is very particularly preferred for horses.

Heavily stressed parts of the body, especially muscles, require special care, for example after athletic use, cooling to avoid permanent swelling. The simplest and most common The method of cooling with water used presupposes the presence of cold water and is often one The bandage needs to be changed for a short period of time in order to achieve adequate cooling.

The object of the invention is to create an aqueous gel-like composition which, due to its combination of active ingredients and a high water content when applied to body parts have a cooling effect and which, if desired, do not require a bandage.

This object is achieved by a gel-like preparation based on a neutralized high molecular weight Polyacrylic acid and water, which still contains a dye. The gel is characterized in that it consists of

0.1 to 1.0% by weight of neutralized polyacrylic acid, 75 to 96% by weight of water

3 to 20% by weight isopropanol
0.05 to 0.5 wt. 96 menthol
0.2 to 5.0 wt. 96 camphor

consists.

0.3 to 0.5% by weight of rosemary oil is also preferred and / or 0.2 to 2.0% by weight arnica flower extract in isopropanol.

A particularly preferred composition consists of:

0.3 to 0.6% by weight polyacrylic acid

85 to 94 wt% water

4 to 10% by weight isopropanol
0.08 to 0.3 wt% menthol

0.2 to 3.0% by weight of camphor and optionally 0.2 to 2.0% by weight of rosemary oil and / or
0.2 to 2% by weight arnica flower extract
in isopropanol.

The following composition is particularly preferred:

0.4% by weight of high molecular weight polyacrylic acid
92.5 wt% water

0.7% by weight aqueous NH ₄ OH (12.5%)

5.0% by weight isopropanol

0.1 wt%. menthol

0.5 wt. - 96 fighters

0.5 wt. 96 arnica flower extract

0.3% by weight of rosemary oil and a small amount of color, for example patent blue V, to give the gel a light blue color.

Carboxy-vinyl polymers, in particular polyacrylic acid with a very high molecular weight, have proven to be particularly suitable for such gels because they produce very high viscosities even in low concentrations in water. Such gels are not breeding grounds for bacteria, even in neutralized form. To set a suitable pH, the polyacrylic acid is neutralized with a suitable base, to a pH in the neutral range. Suitable bases are aqueous ammonia, diisopropylamine, triethylamine, di- (2-ethylhaxyOamine and / or triamylamine. The bases can also be used in mixtures with one another.
The composition is a highly effective so-called fresh gel for heavily stressed body parts and develops a strong cooling effect. Applied to uncovered surfaces of body parts, it has a blood circulation-promoting, anti-inflammatory, anti-inflammatory and decongestant effect, so that overall a strong refreshing effect is achieved, which dissipates heat to a large extent from the tissue.

Due to the gel structure, the preparation can be applied to body parts without difficulty and remains adhere, so that bandaging can easily be dispensed with. However, if so desired, they can air-permeable bandages can be used to create packs with the gel.

A particularly advantageous field of application of the composition according to the invention is use as a fresh gel for heavily stressed horse legs. It acts as a care product to withstand heavy use of the Horses to dissipate the first heat from the run. The strong cooling combination of active ingredients invigorates and refreshes

physical activity and the addition of alcohol has a preventive effect against permanent swellings. The best and most effective way to use it is to use the Apply gel thinly to wet legs of horses that have been sprayed with water, massage in briefly and then apply again in a thicker layer. The legs can remain uncovered, as can a bandage be created. The optimal exposure time is 2 to 12 hours, after which it can be washed off with water will.

In the human area, however, one is usually shorter Prefer exposure times. The gel can be easily washed off with water without any problems.

If necessary, it can also be diluted with water in a ratio of 1:10 to 1:20 to make packs and To carry out ablutions.

The particularly suitable active ingredient combination of isopropanol, menthol, camphor and if necessary, rosemary oil and / or arnica blossom extract in isopropanol creates a pleasant cooling effect without irritating the skin.

For the production, the high molecular weight polyacrylic acid, which is available in powder form, is placed in water stirred in or sprinkled in and left to stand and homogenized by stirring. Then can a dye are introduced and it is neutralized with one of the bases mentioned to a pH value of 6.5 to 8.5.

Menthol, camphor, and rosemary oils are made in isopropanol taken up and premixed, this solution then entered into the gel.

The arnica flower extract is made by preparing arnica flowers with isopropanol for 10 days, then squeezed out and filtered. The macerate obtained in this way can then also be used to absorb menthol, camphor

and optionally rosemary oil can be used in this way to then convert the active ingredient combination into the to be able to enter and incorporate prepared aqueous gel.

example

For a 100 kilo batch of the invention Gels are used:

0.36 kg of high molecular weight polyacrylic acid
0.615 kg of 12.59% aqueous ammonia
92.3 kg of water
5.0 liters of isopropanol
0.1 kg of menthol
0.5 kg of camphor
0.3 to 0.5 liters of rosemary oil
0.5 kg arnica flower extract in isopropanol

For example, 200 mg of patent blue V are used as the dye to give the gel a light blue color.

- <> For production, the water is submitted and the Polyacrylic acid stirred in in the cold and then neutralized with ammonia. The other components will be premixed in isopropanol and then incorporated the active ingredient mixture into the gel.

2> The slightly blue stable gel produced in this way can be packed in cans or tubes and put on the market. The gel-like preparation according to the example is in particular as an animal care product for the care and treatment of heavily used

■ Suitable for parts of the body. When using for cooling The gel is particularly suitable and effective for horse legs after a correspondingly high level of sporting activity and greatly facilitates the maintenance measures required after the stresses.

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Claims (5)

Patent claims: 1. Gel-like preparation based on a neutralized high molecular weight polyacrylic acid and water, which contains a dye, characterized in that they are out 0.1 to 1.0% by weight of neutralized
Polyacrylic acid 75 to 96 wt% water
3 to 20% by weight isopropanol
0.05 to 0.5 wt% menthol
0.2 to 5.0 wt. 96 camphor consists. 2. Gel-like preparation according to claim 1, characterized in that the polyacrylic acid _{is neutralized with aqueous NH 4} OH, isopropylamine, diisopropylamine, triethylamine, di- (2 ethylhexyl) amine, triamylamine or a mixture of one or more of these bases. 3. Gel-like preparation according to claims 1 or 2, characterized in that it still 0.3 to 0.5% by weight of rosemary oil and / or
0.2 to 2.0% by weight arnica flower extract
in isopropanol contains. 4. Use of the gel-like preparation according to Claims 1 to 3 as a care product and remedy in the Human area 5. Use of the gel-like preparation according to Claims 1 to 3 as a care product and remedy in the Veterinary sector.