DE2222491C3 - Steroid-21-salpetersäureester der Pregnanreihe, solche enthaltende Arzneimittel und Verfahren zur Herstellung derselben - Google Patents

Steroid-21-salpetersäureester der Pregnanreihe, solche enthaltende Arzneimittel und Verfahren zur Herstellung derselben

Info

Publication number: DE2222491C3
Authority: DE; Germany
Prior art keywords: nitric acid; steroid; acid esters; acid ester; dione
Prior art date: 1971-05-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

DE2222491A

Other languages

German (de)

English (en)

Other versions

DE2222491A1 (de

DE2222491B2 (de

Inventor

Anna Boor Geb. Mezei

Eva Dr. Czizer

Katalin Goergenyi Geb. Kiss

Sandor Dr. Holly

Mate Kovatsits

Tamas Szen

Jozsef Dr. Szeged Toth

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Richter Gedeon Vegyeszeti Gyar Nyrt

Original Assignee

Richter Gedeon Vegyeszeti Gyar RT

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-05-07

Filing date

1972-05-08

Publication date

1978-05-03

1972-05-08 Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT

1972-11-16 Publication of DE2222491A1 publication Critical patent/DE2222491A1/de

1977-09-29 Publication of DE2222491B2 publication Critical patent/DE2222491B2/de

1978-05-03 Application granted granted Critical

1978-05-03 Publication of DE2222491C3 publication Critical patent/DE2222491C3/de

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE2222491A 1971-05-07 1972-05-08 Steroid-21-salpetersäureester der Pregnanreihe, solche enthaltende Arzneimittel und Verfahren zur Herstellung derselben Expired DE2222491C3 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HURI429A HU164115B (xx)	1971-05-07	1971-05-07

Publications (3)

Publication Number	Publication Date
DE2222491A1 DE2222491A1 (de)	1972-11-16
DE2222491B2 DE2222491B2 (de)	1977-09-29
DE2222491C3 true DE2222491C3 (de)	1978-05-03

Family

ID=11000864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE2222491A Expired DE2222491C3 (de)	1971-05-07	1972-05-08	Steroid-21-salpetersäureester der Pregnanreihe, solche enthaltende Arzneimittel und Verfahren zur Herstellung derselben

Country Status (15)

Country	Link
JP (1)	JPS5330707B1 (xx)
AT (1)	AT316767B (xx)
AU (1)	AU469581B2 (xx)
CA (1)	CA975755A (xx)
CS (2)	CS171259B2 (xx)
DD (1)	DD98668A5 (xx)
DE (1)	DE2222491C3 (xx)
ES (1)	ES402230A1 (xx)
FR (1)	FR2143664A1 (xx)
HU (1)	HU164115B (xx)
NL (1)	NL7206134A (xx)
PL (1)	PL75494B1 (xx)
SE (2)	SE385590B (xx)
SU (1)	SU493963A3 (xx)
YU (1)	YU34701B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5707984A (en) *	1995-12-08	1998-01-13	G. D. Searle & Co.	Steroid nitrite/nitrate ester derivatives useful as anti-inflammatory drugs
US5792758A (en) *	1995-12-08	1998-08-11	G. D. Searle & Co.	Steroid nitrite ester derivatives useful as anti-inflammatory drugs
US5824669A (en) *	1996-03-22	1998-10-20	Nitromed, Inc.	Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
US5837698A (en) *	1996-05-02	1998-11-17	G. D. Searle & Co.	Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs
US5985862A (en) *	1996-05-02	1999-11-16	G.D. Searle & Co.	Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs
IT1285770B1 (it)	1996-10-04	1998-06-18	Nicox Sa	Composti corticoidei
ITMI20020148A1 (it)	2002-01-29	2003-07-29	Nicox Sa	Nuovi corticosteroidi
AU2008213046B2 (en)	2007-02-05	2013-02-14	Nicox S.A.	Nitric oxide releasing steroids
EP2805720B1 (en)	2008-05-28	2019-08-07	ReveraGen BioPharma, Inc.	Non-hormonal steroid modulators of NF-KB for treatment of disease
EP2556083A4 (en)	2010-04-05	2013-12-04	Validus Biopharma Inc	NONHORMONAL STEROID MODULATORS OF NF-KAPPA-B FOR DISEASE TREATMENT
US8716268B2 (en)	2010-06-07	2014-05-06	Chao Liu	Nitrate esters of corticoid compounds useful as diuretics
WO2017004205A1 (en)	2015-06-29	2017-01-05	Reveragen Biopharma, Inc.	NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US11382922B2 (en)	2019-03-07	2022-07-12	Reveragen Biopharma, Inc.	Aqueous oral pharmaceutical suspension compositions

1971
- 1971-05-07 HU HURI429A patent/HU164115B/hu unknown
1972
- 1972-04-20 AT AT345872A patent/AT316767B/de not_active IP Right Cessation
- 1972-04-22 ES ES402230A patent/ES402230A1/es not_active Expired
- 1972-04-26 YU YU1117/72A patent/YU34701B/xx unknown
- 1972-04-28 DD DD162651A patent/DD98668A5/xx unknown
- 1972-05-01 AU AU41722/72A patent/AU469581B2/en not_active Expired
- 1972-05-04 JP JP4376772A patent/JPS5330707B1/ja active Pending
- 1972-05-04 FR FR7215938A patent/FR2143664A1/fr active Granted
- 1972-05-05 NL NL7206134A patent/NL7206134A/xx not_active Application Discontinuation
- 1972-05-05 PL PL15518272A patent/PL75494B1/pl unknown
- 1972-05-05 SU SU1783400A patent/SU493963A3/ru active
- 1972-05-05 CS CS2266*[A patent/CS171259B2/cs unknown
- 1972-05-05 CS CS3050A patent/CS171258B2/cs unknown
- 1972-05-05 SE SE7205915A patent/SE385590B/xx unknown
- 1972-05-05 CA CA141,366A patent/CA975755A/en not_active Expired
- 1972-05-08 DE DE2222491A patent/DE2222491C3/de not_active Expired
1975
- 1975-03-21 SE SE7503290A patent/SE7503290L/xx unknown

Also Published As

Publication number	Publication date
CA975755A (en)	1975-10-07
DE2222491A1 (de)	1972-11-16
DE2222491B2 (de)	1977-09-29
FR2143664A1 (en)	1973-02-09
ES402230A1 (es)	1975-03-16
SE385590B (sv)	1976-07-12
PL75494B1 (xx)	1974-12-31
CS171259B2 (xx)	1976-10-29
SU493963A3 (ru)	1975-11-28
DD98668A5 (xx)	1973-07-05
NL7206134A (xx)	1972-11-09
AU4172272A (en)	1973-11-08
YU34701B (en)	1979-12-31
AU469581B2 (en)	1976-02-19
YU111772A (en)	1979-07-10
JPS5330707B1 (xx)	1978-08-29
AT316767B (de)	1974-07-25
HU164115B (xx)	1973-12-28
FR2143664B1 (xx)	1976-07-02
CS171258B2 (xx)	1976-10-29
SE7503290L (xx)	1975-03-21

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Legal Events

Date	Code	Title	Description
1978-05-03	C3	Grant after two publication steps (3rd publication)
1982-08-26	8339	Ceased/non-payment of the annual fee