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DE19375071I2 - Oberflächenaktive Zusammensetzungen für die Lunge . - Google Patents

Oberflächenaktive Zusammensetzungen für die Lunge .

Info

Publication number
DE19375071I2
DE19375071I2 DE19813164207 DE3164207C DE19375071I2 DE 19375071 I2 DE19375071 I2 DE 19375071I2 DE 19813164207 DE19813164207 DE 19813164207 DE 3164207 C DE3164207 C DE 3164207C DE 19375071 I2 DE19375071 I2 DE 19375071I2
Authority
DE
Germany
Prior art keywords
lung
surfactant composition
synthetic
fatty alcohol
alveolar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE19813164207
Other languages
English (en)
Other versions
DE3164207D1 (en
Inventor
John A Clements
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California San Diego UCSD
Original Assignee
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley
Application granted granted Critical
Publication of DE19375071I2 publication Critical patent/DE19375071I2/de
Active legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Dental Preparations (AREA)
DE19813164207 1980-10-24 1981-10-14 Oberflächenaktive Zusammensetzungen für die Lunge . Active DE19375071I2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/200,216 US4312860A (en) 1980-10-24 1980-10-24 Lung surfactant compositions

Publications (1)

Publication Number Publication Date
DE19375071I2 true DE19375071I2 (de) 2006-05-04

Family

ID=22740789

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19813164207 Active DE19375071I2 (de) 1980-10-24 1981-10-14 Oberflächenaktive Zusammensetzungen für die Lunge .
DE8181108298T Expired DE3164207D1 (en) 1980-10-24 1981-10-14 Lung surfactant compositions

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8181108298T Expired DE3164207D1 (en) 1980-10-24 1981-10-14 Lung surfactant compositions

Country Status (9)

Country Link
US (1) US4312860A (de)
EP (1) EP0050793B1 (de)
JP (1) JPS5799524A (de)
AT (1) ATE7853T1 (de)
BG (1) BG60737B2 (de)
CA (1) CA1184503A (de)
CS (1) CS384991A3 (de)
DE (2) DE19375071I2 (de)
NL (1) NL930059I2 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3229179C2 (de) * 1982-08-05 1986-04-17 A. Nattermann & Cie GmbH, 5000 Köln Lungensurfactant
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US5840527A (en) * 1984-12-11 1998-11-24 Byk Gulden Lomberg Chemische Fabrik Gmbh Recombinant alveolar surfactant protein
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US5169761A (en) * 1984-12-11 1992-12-08 California Biotechnology Inc. Dna encoding and expression systems for alveolar surfactant proteins
AU587472B2 (en) * 1985-05-22 1989-08-17 Liposome Technology, Inc. Liposome inhalation method and system
US5110806A (en) * 1985-06-26 1992-05-05 The Regents Of The University Of California Lung surfactant compositions
US4826821A (en) * 1985-06-26 1989-05-02 The Regents Of The University Of California Lung surfactant compositions
FR2586587B1 (fr) * 1985-08-30 1987-10-23 Adir Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent.
US4812314A (en) * 1986-02-24 1989-03-14 Yissum Research & Dev. Co. Of The Hebrew Univ. Of Jerusalem And Hadassah Medical Organization Lipid replacement therapy
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
IT1203873B (it) * 1987-04-08 1989-02-23 Chiesi Farma Spa Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e
US4861756A (en) * 1988-03-08 1989-08-29 Merrell Dow Pharmaceuticals Inc. Synthetic pulmonary surfactant
US5207220A (en) * 1989-12-12 1993-05-04 Burroughs Wellcome Co. Method for administering pharmaceuticals, including liquid surfactant, to the lungs
US5614216A (en) * 1990-10-17 1997-03-25 The Liposome Company, Inc. Synthetic lung surfactant
GB9120005D0 (en) * 1991-09-19 1991-11-06 Wellcome Found Method of administering phospholipid dispersions
US5622715A (en) * 1994-06-10 1997-04-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of improving renal function
US6235308B1 (en) 1994-06-10 2001-05-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of treating hypertension
US5698537A (en) * 1996-06-18 1997-12-16 Clarion Pharmaceuticals Inc. Method of lowering the viscosity of mucus
US5883084A (en) * 1998-06-08 1999-03-16 Clarion Pharmaceuticals Inc. Treatment of respiratory diseases utilizing α-tocopheryl-phosphocholine
US6180142B1 (en) * 1998-08-21 2001-01-30 The Regents Of The University Of California Reduction of surfactant inactivation in pulmonary surfactant therapy
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
EP1265527A2 (de) * 2000-03-13 2002-12-18 Medi-Physics, Inc. Diagnostische verfahren unter verwendung direkter injizierung von gasförmigem hyperpolarisiertem 129 xenon
GB0026239D0 (en) * 2000-10-26 2000-12-13 Britannia Pharmaceuticals Ltd Surface active lipids in treatment of wet lung
CA2564868C (en) * 2004-04-28 2013-11-26 Molecules For Health, Inc. Methods for treating or preventing restenosis and other vascular proliferative disorders
US7638493B2 (en) * 2004-04-29 2009-12-29 Sannamu Lee Artificial pulmonary surfactant compositions and use of the same
CA2702094C (en) 2007-10-10 2018-05-01 Parion Sciences, Inc. Delivering osmolytes by nasal cannula
US8945605B2 (en) 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
WO2012170677A1 (en) 2011-06-07 2012-12-13 Parion Sciences, Inc. Methods of treatment
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
SG11201407867VA (en) 2012-05-29 2014-12-30 Parion Sciences Inc Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases
CA2896686A1 (en) 2012-12-17 2014-06-26 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
WO2014099676A1 (en) 2012-12-17 2014-06-26 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
NZ709197A (en) 2012-12-17 2020-06-26 Parion Sciences Inc 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
US11219843B2 (en) * 2019-07-08 2022-01-11 Nik Paya Karen Pharmed Extraction of animal-derived pulmonary surfactants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE388023C (de) * 1922-02-14 1924-01-07 Chem Fab Verfahren zur Herstellung von waesserigen Lezithinemulsionen
US3577446A (en) * 1968-09-09 1971-05-04 American Home Prod Phosphatidylalkanolamine derivatives
DE2629135A1 (de) * 1976-06-29 1978-01-12 Nattermann A & Cie Neue phospholipid-derivate von prostaglandinen und verfahren zu ihrer herstellung
DE2900300A1 (de) * 1979-01-05 1980-07-17 Lebrecht Von Dr Klitzing Verfahren einer prophylaxe zur vermeidung des atemnotsyndroms bei fruehgeborenen und bei der schocklunge

Also Published As

Publication number Publication date
JPS5799524A (en) 1982-06-21
EP0050793A1 (de) 1982-05-05
JPH0343252B2 (de) 1991-07-01
BG60737B2 (bg) 1996-01-31
DE3164207D1 (en) 1984-07-19
CS384991A3 (en) 1992-10-14
US4312860A (en) 1982-01-26
CA1184503A (en) 1985-03-26
ATE7853T1 (de) 1984-06-15
NL930059I1 (nl) 1993-09-01
NL930059I2 (nl) 1994-01-03
EP0050793B1 (de) 1984-06-13

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